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Dietary supplement

Arthritis-Ease Ingredients & Drug Interactions

by Earth Friend Herb Co.

Arthritis-Ease label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Arthritis-Ease against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Arthritis-Ease is a dietary supplement by Earth Friend Herb Co. with 4 active ingredients. Its ingredients are commonly taken for source of iodine and minerals, thyroid support, respiratory issues and cough.Based on those ingredients, 23 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Irish Moss, Lobelia, Hydrangea. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Arthritis-Ease by Earth Friend Herb Co.

Ask about any prescription or over-the-counter medication and we check it for interactions with Arthritis-Ease by Earth Friend Herb Co. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Arthritis-Ease by Earth Friend Herb Co.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.

Arthritis-Ease contains 4 ingredients total. The active ingredients are Irish Moss, Lobelia, Hydrangea, and Iceland Moss — each is a plant-derived ingredient used traditionally for joint support.

The product is delivered as a liquid and also contains alcohol and glycerin as inactive ingredients (these help preserve and deliver the herbs).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness data we hold is limited. Lobelia is rated possibly ineffective for smoking cessation, which is not the intended use here — no effectiveness information is on file for any of the ingredients for arthritis or joint support.

The evidence, ingredient by ingredient Sea Moss Lobelia Hydrangea Iceland Moss

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lobelia carries serious toxicity concerns and is rated likely unsafe in pregnancy and while breastfeeding. It can cause nausea, vomiting, diarrhea, dizziness, throat irritation, and at higher doses (600 mg or above) more severe effects like rapid heart rate, low blood pressure, convulsions, and even death — some users have reported these side effects at doses as low as 50 mg.

Hydrangea and Iceland Moss have limited human safety data; both should be avoided in pregnancy and while breastfeeding. Hydrangea may cause stomach upset, dizziness, and chest tightness.

Iceland Moss can irritate the stomach and may be contaminated with lead if consumed long-term in large amounts.

Side effects, ingredient by ingredient Sea Moss Lobelia Hydrangea Iceland Moss

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Lobelia, Hydrangea, Sea Moss.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 23 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, do not start Arthritis-Ease without checking with your doctor or pharmacist — both lobelia and hydrangea may increase lithium levels in your blood, and your dose may need adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is not recommended for pregnant or breastfeeding people, especially because of lobelia's toxicity profile. If you take lithium, check with your pharmacist or doctor before starting — both lobelia and hydrangea may affect how your body handles it.

Anyone with a history of stomach problems or sensitivity to these herbs should also talk to their pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Arthritis-Ease, straight from the product label.

Brand Earth Friend Herb Co.
Net contents 1 Fluid Ounce; 30 mL
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 323583
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Arthritis-Ease by Earth Friend Herb Co., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
10 Drop(s)
Servings per container
30
IngredientAmount% DV
Irish Moss0 NP--
Lobelia0 NP--
Hydrangea0 NP--
Iceland Moss0 NP--

Other ingredients: Alcohol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Use 10 drops 3x daily. Take straight-then drink water.

Precautions

Keep away from children.

Not for use with pregnancy or nursing.

General Statements

An Elijah Free formula

Formulation

All certified organic or wild crafted herbs.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Arthritis-Ease by Earth Friend Herb Co. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Arthritis-Ease label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Arthritis-Ease by Earth Friend Herb Co.

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Irish Moss

Interacts with
22 drugs
0 NP per serving

Sea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human...

Irish Moss monograph & interactions

Lobelia

Interacts with
1 drug
0 NP per serving

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking...

Lobelia monograph & interactions

Hydrangea

Interacts with
1 drug
0 NP per serving

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to...

Hydrangea monograph & interactions

Iceland Moss

No known
interactions
0 NP per serving

Iceland moss is a lichen traditionally used as a soothing remedy for dry cough and throat or mouth irritation, mainly because of its mucilage (gel-for...

Iceland Moss monograph & interactions

Other (inactive) ingredients: Alcohol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Arthritis-Ease by Earth Friend Herb Co. Drug Interactions

Want to check YOUR meds against Arthritis-Ease?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
23Drugs
23 Moderate

Ingredients driving the most interactions

Irish Moss 22
Lobelia 1
Hydrangea 1

Individual Drug Interactions

The ingredients in Arthritis-Ease interact with 23 drugs. Click any drug to see the details.

3 of the 4 ingredients in Arthritis-Ease interact with drugs. Each result below shows which ingredient is responsible. Irish Moss Lobelia Hydrangea

Each ingredient & the kinds of drugs it affects

For each ingredient in Arthritis-Ease with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Irish Moss3 drug types · 22 drugs

Amiodarone (Cordarone)

Theoretically, combining sea moss with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with sea moss, which contains approximately 4-7 mcg of iodine per gram, might increase the risk of adverse effects from iodine, including altered thyroid function.

Likelihood Possible Evidence D
Antithyroid Drugs

Due to its iodine content, sea moss might alter the effects of antithyroid drugs.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of antithyroid drugs.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, sea moss might alter the effects of thyroid hormone.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of thyroid hormone.

Likelihood Possible Evidence D
Irish Moss full monograph & interactions

Lobelia1 drug type · 1 drug

Lithium

Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Lobelia full monograph & interactions

Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Hydrangea full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Arthritis-Ease, from the product label.

Earth Friend Herb Co.

See all Earth Friend Herb Co. products
Name
Exsula Foods Inc.
Street Address
PO Box 44459
City
Tacoma
State
WA
ZipCode
98448
Phone Number
253-874-9092
Web Address
www.exsula.com
Pharmacist Counseling Corner

Arthritis-Ease by Earth Friend Herb Co.: Common Questions

Does Arthritis-Ease by Earth Friend Herb Co. interact with any medications?
Yes. Based on its ingredients, Arthritis-Ease has a known interaction with 23 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Arthritis-Ease contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Lobelia is rated likely unsafe in both pregnancy and breastfeeding due to toxicity concerns. Hydrangea and Iceland Moss also lack enough safety data to recommend them during pregnancy or while breastfeeding. Talk with your doctor or pharmacist for other options.
What's lobelia, and why is it in here?
Lobelia is a plant traditionally used for various purposes; it's included in this arthritis formula for its herbal properties. The concern is that lobelia can be toxic, especially at higher doses, and even small amounts (as low as 50 mg) can cause nausea, vomiting, or dizziness.
How much lobelia is in each dose?
The product facts don't list the dose per serving, so you'll need to check the label or contact the manufacturer to know how much lobelia you'd be taking.
What are the inactive ingredients?
This liquid contains alcohol and glycerin — these are not active herbs but help preserve and deliver the product. If you avoid alcohol, note that this formula contains it.
Can this really help arthritis?
We don't have effectiveness data on file for any of these ingredients specifically for arthritis or joint support, so I can't tell you from the research we hold whether this product works for that purpose.
What side effects might I notice?
Lobelia can cause nausea, vomiting, diarrhea, dizziness, tremors, and throat irritation even at low doses. Hydrangea may cause stomach upset or dizziness. At high doses, lobelia carries risks of rapid heart rate, low blood pressure, and serious toxicity. Stop and call your doctor if you feel very unwell.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Arthritis-Ease label
Go deeper

The Full Monographs Behind Arthritis-Ease’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sea Moss

Interacts with 22 drugs

Sea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human evidence for most of its health claims i...

Read the full Sea Moss monograph → Herb & supplement monograph

Lobelia

Interacts with 1 drug

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...

Read the full Lobelia monograph → Herb & supplement monograph

Hydrangea

Interacts with 1 drug

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to confirm it works for any condition. Beca...

Read the full Hydrangea monograph → Herb & supplement monograph

Iceland Moss

Iceland moss is a lichen traditionally used as a soothing remedy for dry cough and throat or mouth irritation, mainly because of its mucilage (gel-forming fibers). High-quality human studies...

Read the full Iceland Moss monograph →
Sources

Sources & How We Checked

Arthritis-Ease's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sea Moss 3 references
  1. Darias-Rosales J, Rubio C, Gutiérrez ÁJ, Paz S, Hardisson A. Risk assessment of iodine intake from the consumption of red seaweeds (Palmaria palmata and Chondrus crispus). Environ Sci Pollut Res Int 2020;27(36):45737-45741. PubMed
  2. U.S. Department of Agriculture (USDA). Agricultural Research Service. FoodData Central. Seaweed, irishmoss, raw. April 2019. Available at: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168456/nutrients. Accessed Aug. 30, 2022.
  3. Palmieri B, Vadalà M, Laurino C. Clinical effects of overwintered-stressed Chondrus Crispus and non-overwintered-stressed Chondrus crispus dietary supplementations. Asian J Med Sci. 2018; 9(6): 7-13. DOI

See these in context on the Sea Moss monograph →

Lobelia 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
  5. Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
  6. Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed

See these in context on the Lobelia monograph →

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Iceland Moss 3 references
  1. Tyler VE. Herbs of Choice. Binghamton, NY: Pharmaceutical Products Press, 1994.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Iceland Moss monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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