Bacopa Monnieri 1000 mg Ingredients & Drug Interactions
by tnvitamins
What is this page for?
First and foremost: checking Bacopa Monnieri 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bacopa Monnieri 1000 mg is a dietary supplement by tnvitamins with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 930 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacopa leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bacopa Monnieri 1000 mg by tnvitamins
Ask about any prescription or over-the-counter medication and we check it for interactions with Bacopa Monnieri 1000 mg by tnvitamins — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bacopa Monnieri 1000 mg by tnvitamins
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: bacopa leaf extract at 1000 mg per capsule. Bacopa is a plant traditionally used in Ayurvedic medicine, and the extract form concentrates its active compounds.
The inactive ingredients are rice flour, magnesium stearate, and gelatin (the capsule itself).
Does it work?
Couldn't assess
The evidence for bacopa's effectiveness isn't established in the data we hold. Studies have looked at it for Alzheimer disease, sexual dysfunction, ADHD, back pain, and cognitive function and impairment, but the data we have rates all of these as insufficient reliable evidence to rate.
That doesn't mean it doesn't work — it means larger, high-quality trials are needed to say for sure.
How safe is it?
Well-documented data
Bacopa is generally well tolerated in studies, but quality and long-term safety data are limited. The most common side effects are gastrointestinal: abdominal cramps, diarrhea, nausea, dry mouth, and headache.
Rates of stomach or bowel upset have ranged from 12% to 30% in trials. Some people have also reported drowsiness, insomnia, vivid dreams, bloating, and loss of appetite.
There isn't enough safety information to use bacopa during pregnancy or while breastfeeding — the data advises against it in both cases. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist before taking it.
Meds to double-check
Moderate interaction found
Before taking bacopa, check with your doctor or pharmacist if you take any medications broken down by your liver's CYP450 enzymes (CYP1A2, CYP2C19, CYP2C9, or CYP3A4 substrates) — bacopa may raise their levels and side effects. Also flag anticholinergic drugs, cholinergic drugs, cevimeline (Evoxac), or thyroid hormone replacements.
Use the medication search tool on this page to look up your prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Bacopa might appeal to you if you're looking into traditional remedies for memory or focus, but keep in mind the evidence isn't clear yet. The big thing to watch is medication interactions — it affects how your liver processes a very large number of drugs, so you'll want to check your exact prescriptions before starting.
Talk it over with your doctor or pharmacist first, especially if you take any medications for anticholinergic effects, cholinergic conditions, thyroid problems, or dry mouth.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bacopa Monnieri 1000 mg, straight from the product label.
| Brand | tnvitamins |
|---|---|
| Barcode (UPC) | X0033XXK63 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 276869 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bacopa Monnieri 1000 mg by tnvitamins, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bacopa leaf extract | 1000 mg | -- |
Other ingredients: Rice Flour, Magnesium Stearate, Gelatin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement for adults, take two (2) capsules daily, preferably with a meal or as directed by a health care professional.
Formula
Bacopa monnieri is a revered Ayurvedic herb.
Bacopa monnieri is a revered Ayurvedic herb.
Bacopa monnieri 1000 mg per serving
Precautions
Keep out of reach of children.
Caution: Pregnant or lactating women should consult a doctor before use.
If you are under medical supervision, please consult a doctor before use. Discontinue use and consult a doctor if any adverse reactions occur.
Storage
Store in a cool, dry place.
General Statements
Bacopa monnieri capsule...psules) by TNVitamins New
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bacopa Monnieri 1000 mg by tnvitamins label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bacopa Monnieri 1000 mg by tnvitamins
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Bacopa leaf extract
Interacts with930 drugs
Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...
Bacopa leaf extract monograph & interactionsOther (inactive) ingredients: Rice Flour, Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.
Bacopa Monnieri 1000 mg by tnvitamins Drug Interactions
HelloPharmacist Interaction Report
Bacopa Monnieri 1000 mg by tnvitamins has documented interactions with a significant number of medications.
The most serious concern is with drugs metabolized by your liver's cytochrome P450 enzymes — a system that breaks down many prescriptions. Bacopa may slow the clearance of these drugs, raising their levels in your blood and increasing the risk of side effects.
The affected enzyme systems are CYP1A2, CYP2C19, CYP2C9, and CYP3A4, all rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Beyond liver metabolism, bacopa may interfere with anticholinergic drugs (medications that block acetylcholine, used for conditions like overactive bladder and motion sickness) and cholinergic drugs (which boost acetylcholine, used in some cases of myasthenia gravis or Alzheimer disease) — it could weaken one and amplify the other. Bacopa also carries a Moderate interaction with cevimeline (Evoxac), a drug for dry mouth in Sjogren syndrome; one documented case involved serious symptoms like rapid heartbeat and nausea after a single bacopa dose.
There's also a Minor interaction with thyroid hormone, as bacopa may add to its effects.
Altogether, these interactions span 931 individual medications. Before you start bacopa, use the medication checker below to see if any of your prescriptions fall into these categories, and discuss the results with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bacopa Monnieri 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bacopa Monnieri 1000 mg interact with 930 drugs. Click any drug to see the details.
1 of the 1 ingredient in Bacopa Monnieri 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Bacopa leaf extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
Read the full Bacopa Leaf Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acalabrutinib interactionAcepromazineAtravet
How Acepromazine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Leaf Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractAnticholinergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Bacopa Monnieri 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Bacopa Leaf Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bacopa Monnieri 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bacopa leaf extract
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Brand information
Manufacturer and brand details for Bacopa Monnieri 1000 mg, from the product label.
tnvitamins
See all tnvitamins products- Name
- Total Nutrition, Inc.
- City
- Farmingdale
- State
- NY
- ZipCode
- 11735
- Phone Number
- (631) 694-9777
Bacopa Monnieri 1000 mg by tnvitamins: Common Questions
Does Bacopa Monnieri 1000 mg by tnvitamins interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is bacopa and what's it used for?
What are the most common side effects?
Is it safe to take while pregnant or breastfeeding?
How does bacopa interact with medications?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bacopa Monnieri 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bacopa Monnieri 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bacopa Monnieri 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacopa 12 references
- Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
- Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
- Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
- Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
- Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
- Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
- Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
- Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
- Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
- Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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