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Dietary supplement

Beet Root 1000 mg Ingredients & Drug Interactions

by Spring Valley

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Beet Root 1000 mg is a dietary supplement by Spring Valley with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Beet Root 1000 mg by Spring Valley

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beet at 1000 mg per capsule. Beet is a root vegetable used in supplements chiefly for its potential effects on exercise performance and muscle soreness.

The capsule itself is filled with inactive ingredients—rice powder, gelatin, vegetable magnesium stearate, and silica—which are binders and flow agents that help deliver the beet powder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: general wellness and phytonutrient support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Hypertension, Pregnancy-induced hypertension, circulation — and 2 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Exercise-induced muscle soreness.
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Pregnancy-induced hypertension, Pulmonary hypertension, Exercise-induced muscle damage.

Beet shows possibly effective evidence for athletic performance and for reducing exercise-induced muscle soreness. The evidence for COPD is possibly ineffective.

For cholesterol levels (dyslipidemia) and cognitive function, there isn't enough reliable evidence in our data to rate it either way. If you're considering this for a specific health goal, talk with your pharmacist about what the research actually supports.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and generally well tolerated by most adults. However, concentrated supplements like this one lack the long-term safety data that food forms have, so use caution—especially with long-term use.

Short-term use for medicinal purposes appears well tolerated. The most common side effects are harmless: red stools and red urine from the pigment.

Rarely, black stools have been reported; one case involved a patient on blood thinners. Theoretically, large amounts could lower calcium levels or stress the kidneys, though this is uncommon.

We hold no safety data for beet during lactation.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting, double-check any medications metabolized by the liver enzyme CYP3A4 (Moderate severity)—this is the most serious interaction. Also check CYP1A2 substrates and blood pressure medications (both Minor severity).

Use the search tool below with your exact drug names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Beet Root may appeal to you if you're an athlete or regularly exercise and want to explore its possible effects on performance or muscle soreness. If you take any medications broken down by your liver—especially CYP3A4 or CYP1A2 substrates—or any blood pressure medication, check with your pharmacist first.

The interactions are theoretical but plausible, and you'll want to make sure this supplement won't interfere with your drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Root 1000 mg, straight from the product label.

Brand Spring Valley
Barcode (UPC) 681131151108
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2018
DSLD ID 178424
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Root 1000 mg by Spring Valley, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
681131151108
IngredientAmount% DV
Beet1000 mg--

Other ingredients: Rice powder, Gelatin, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Please recycle

General wellness Used for centuries for its naturally-occurring phytonutrients.

Product of China

General

Item No. WM 8860 B8860 A 446901

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Beet Root 1000 mg per serving

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take two capsules up to three times daily, preferably with meals.

Formulation

No gluten, dairy, soy, peanuts, artificial colors, artificial flavors, sweeteners, preservatives.

Precautions

Warning: Pregnant or nursing women, individuals taking medication(s) or persons who have a health condition should consult their doctor before using this product.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

For your protection, do not use if seal under cap is broken or missing.

Storage

Store at room temperature 59(0)- 86(0)F (15(0)- 30(0)C). Keep bottle tightly closed.

Brand IP Statement(s)

Quality Guaranteed Spring Valley products are produced under strict quality guidelines. If you are unhappy with this product, we’ll replace it or refund your money.

See for yourself

Beet Root 1000 mg by Spring Valley label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beet Root 1000 mg by Spring Valley

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Beet

Interacts with
861 drugs
1000 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet monograph & interactions

Other (inactive) ingredients: Rice powder, Gelatin, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Root 1000 mg by Spring Valley Drug Interactions

Want to check YOUR meds against Beet Root 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet 861

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Root 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Beet Root 1000 mg, from the product label.

Spring Valley

See all Spring Valley products
Name
Wal-Mart Stores, Inc.
City
Bentonville
State
AR
ZipCode
72716
Phone Number
1-866-251-1662
Web Address
Walmart.com/springvalley
Pharmacist Counseling Corner

Beet Root 1000 mg by Spring Valley: Common Questions

Does Beet Root 1000 mg by Spring Valley interact with any medications?
Yes. Based on its ingredients, Beet Root 1000 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Root 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet root interfere with my blood pressure medication?
Beet contains nitrates that can relax blood vessels and lower blood pressure, so there's a theoretical Minor-severity interaction with blood pressure drugs. However, one clinical study using concentrated beetroot juice found no significant blood pressure change. Still, check your specific medication with the tool on this page to be sure.
What are the side effects?
The most common are red stools and red urine—completely harmless, just from the beet pigment. Black stools have been reported rarely. In very large amounts, beet could theoretically lower calcium or stress the kidneys, but these are uncommon.
Does this supplement actually boost athletic performance?
The evidence says beet is possibly effective for athletic performance and for reducing muscle soreness after exercise. That means some research supports it, but the evidence isn't definitive. Talk with your pharmacist about whether it's worth trying for your goals.
Can I take this while breastfeeding?
We don't hold safety data for beet during lactation. Talk with your doctor or pharmacist—they can help you weigh whether this supplement is right for you during breastfeeding.
Why does the label say it's 1000 mg if beet as food is safe?
Beet the food is fine and widely eaten. But this is a concentrated supplement, and concentrated forms lack the long-term safety evidence that regular food has. We advise caution, especially with ongoing use.
What are the inactive ingredients?
The capsule contains rice powder, gelatin, vegetable magnesium stearate, and silica—these are standard binders and flow agents that help deliver the active beet ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Root 1000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Root 1000 mg label
Go deeper

The Full Monographs Behind Beet Root 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Beet Root 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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