Belly Mend Ingredients & Drug Interactions
by Bioray
What is this page for?
First and foremost: checking Belly Mend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Belly Mend is a dietary supplement by Bioray with 1 active ingredient. Its ingredients are commonly taken for digestive health and regularity, antibiotic-associated diarrhea, irritable bowel syndrome (ibs).Based on those ingredients, 1,494 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are CytoFlora Probiotics Lystates. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Belly Mend by Bioray
Ask about any prescription or over-the-counter medication and we check it for interactions with Belly Mend by Bioray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Belly Mend by Bioray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Belly Mend contains 20 ingredients, including several live probiotic strains and herbal extracts. The probiotics — Lactobacillus acidophilus, Lactobacillus helveticus, Bifidobacterium longum, Bifidobacterium bifidum, and others — are meant to support gut health.
The herbal components include milk thistle, reishi mushroom, maitake mushroom, turkey tail mushroom, agaricus mushroom, cilantro, olive, chlorella (as NDF), and red root. The liquid also contains inactive ingredients: glycerin, deionized water, and natural raspberry flavor.
Does it work?
Moderate evidence
The probiotics in this product show mixed evidence. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, helicobacter pylori infection, and bacterial vaginosis, but possibly ineffective for atopic disease.
Bifidobacterium bifidum is possibly effective for IBS and respiratory tract infections. Most other probiotic strains and herbal ingredients in this product — including reishi, maitake, agaricus, turkey tail, and milk thistle — either have insufficient evidence to rate or show no clear benefit.
Milk thistle alone is possibly effective for diabetes, and turkey tail is possibly effective for cancer, but the evidence for most other uses listed is not established in our data.
How safe is it?
Well-documented data
The probiotic strains are generally well tolerated in healthy adults and children, though they can rarely cause gastrointestinal side effects like bloating, gas, abdominal pain, and diarrhea — especially early on. There's a rare but serious concern: in very ill or immunocompromised people, these live organisms can occasionally cause bloodstream infections (bacteremia) or sepsis, so those with weakened immune systems should check with their doctor first.
Reishi mushroom is generally well tolerated short-term but long-term safety isn't well studied; it should be avoided in pregnancy and breastfeeding. Milk thistle is well tolerated but should be avoided in pregnancy; safety during breastfeeding is limited.
Cilantro, agaricus, turkey tail, and maitake should all be avoided in pregnancy and breastfeeding due to insufficient safety data. Chlorella is generally well tolerated but can cause photosensitivity in some people and should be avoided in pregnancy and breastfeeding.
Red root has very little modern safety data, so it's best used only under professional guidance and avoided in pregnancy and breastfeeding.
Meds to double-check
Moderate interaction found
Before taking Belly Mend, check with your pharmacist if you're on antibiotic drugs (probiotics can be killed by them), blood thinners like warfarin, blood pressure medications, diabetes medications, morphine, chemotherapy drugs (especially cyclophosphamide and tamoxifen), or hepatitis C antivirals. The interaction severity for most of these is Moderate.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Belly Mend may appeal to people looking for probiotic and herbal digestive support, particularly those interested in IBS or post-antibiotic gut health. However, if you take blood thinners, diabetes medications, blood pressure medications, or are seriously ill or immunocompromised, talk with your pharmacist or doctor first — this product has several documented interactions.
If you're pregnant or breastfeeding, discuss it with your healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 14 of 20 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Belly Mend, straight from the product label.
| Brand | Bioray |
|---|---|
| Barcode (UPC) | 646858160055 |
| Net contents | 60 mL; 2 Fluid Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 321518 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Belly Mend by Bioray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 720 mg | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Lactobacillus salivarius | 0 NP | -- |
| Bifidobacterium longum infantis | 0 NP | -- |
| Lactobacillus plantarum | 0 NP | -- |
| Bifidobacterium longum | 0 NP | -- |
| Bifidobacterium bifidum | 0 NP | -- |
| Lactobacillus paracasei | 0 NP | -- |
| Lactobacillus casei | 0 NP | -- |
| Lactobacillus helveticus | 0 NP | -- |
| Lactobacillus rhamnosus | 0 NP | -- |
| Lactobacillus reuteri | 0 NP | -- |
| Olive | 0 NP | -- |
| Reishi Mushroom | 0 NP | -- |
| Milk Thistle | 0 NP | -- |
| Cilantro | 0 NP | -- |
| Agaricus blazei Mushroom | 0 NP | -- |
| Turkey Tail Mushroom | 0 NP | -- |
| Maitake Mushroom | 0 NP | -- |
| CytoFlora Probiotics Lystates | 0 NP | -- |
| NDF | 0 NP | -- |
| Red Root | 0 NP | -- |
Other ingredients: Glycerin, Water, Deionized, Raspberry Flavor, Natural
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Belly Mend ingredients are traditionally used to support healthy gastrointestinal balance and intestinal integrity while enhancing healthy gut/brain connection.
Gluten free Alcohol free Non-GMO Soy free Dairy free
Vegan
Gut support Immunity Replenish
Our probiotics are hypoallergenic, in a dairy free rice base.
Suggested/Recommended/Usage/Directions
For teens & adults Intake instructions: Shake well. Take 2 ml, 1 time per day in water, juice, or tea. Recommended for a minimum of 2-4 months or as needed depending upon individual imbalances.
Daily
Precautions
If pregnant or nursing, consult with a healthcare professional.
Keep out of reach of children.
General Statements
100% recyclable
60 mL (2 fl oz) bottle
Seals/Symbols
Made in the USA cGMP Certified
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
11-strain probiotic blend with medicinal mushrooms & micronized chlorella
FDA Statement of Identity
Daily Dietary Supplement
Brand IP Statement(s)
Bioray and NDF are registered trademarks of Bioray Inc.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Belly Mend by Bioray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Belly Mend by Bioray
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Proprietary Blend
Other (inactive) ingredients: Glycerin, Water, Deionized, Raspberry Flavor, Natural. These complete the product’s ingredient list but are not active constituents.
Belly Mend by Bioray Drug Interactions
HelloPharmacist Interaction Report
Belly Mend by Bioray contains multiple probiotic and herbal ingredients, several of which interact with medications.
The most serious interactions we've documented are Moderate in severity.
Read the full breakdown — every affected drug type, severity by severity
Multiple probiotic strains (Lactobacillus acidophilus, Bifidobacterium longum infantis, Bifidobacterium longum, Bifidobacterium bifidum, and Lactobacillus helveticus) all interact with antibiotic drugs. Because these probiotics contain live organisms, antibiotics can kill them and reduce their effectiveness.
You'll want to separate doses — take your antibiotic at a different time than this product.
Milk thistle in this product interacts with a broad range of medications: blood thinners like warfarin (which may increase bleeding risk), diabetes medications, morphine, several hepatitis C antivirals, and drugs processed through specific liver pathways. Reishi mushroom may lower blood pressure and thin the blood, so it can interact with blood pressure medications and blood thinners.
Cilantro may affect blood sugar control and blood pressure, and could interact with sedating drugs. Both Agaricus and Turkey Tail mushrooms may increase the risk of low blood sugar (hypoglycemia) with diabetes medications.
Turkey Tail also interacts with cyclophosphamide (a chemotherapy drug) and tamoxifen. Maitake mushroom can lower blood pressure and blood sugar.
Chlorella (in the NDF ingredient) contains vitamin K and may reduce warfarin's effectiveness, and it can cause photosensitivity reactions with certain drugs.
We could not check Lactobacillus salivarius, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus casei, and Lactobacillus rhamnosus — we hold no interaction data for these ingredients. Altogether, these interactions span 1,446 individual medications.
Use the medication checker below with your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Belly Mend?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Belly Mend interact with 1,494 drugs. Click any drug to see the details.
1 of the 1 ingredient in Belly Mend interact with drugs. Each result below shows which ingredient is responsible. CytoFlora Probiotics Lystates
AbciximabReoPro
How Abciximab interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Reishi MushroomAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Reishi MushroomAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Abrocitinib interactionTurkey Tail MushroomCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might inhibit CYP2C9.
Read the full Turkey Tail Mushroom + Abrocitinib interactionMilk ThistleCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
It is unclear if milk thistle inhibits CYP2C9; research is conflicting.
Read the full Milk Thistle + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Belly Mend — through 6 ingredients. Tap an ingredient for the detail:
Reishi MushroomAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mushroom + Acarbose interactionMaitake MushroomAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Maitake Mushroom + Acarbose interactionMilk ThistleAntidiabetes Drugs Moderate
Interaction Summary
Taking milk thistle with antidiabetes drugs may increase the risk of hypoglycemia.
Read the full Milk Thistle + Acarbose interactionTurkey Tail MushroomAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking turkey tail mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Turkey Tail Mushroom + Acarbose interactionCilantroAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cilantro + Acarbose interactionAgaricus Blazei MushroomAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Agaricus Blazei Mushroom + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Maitake MushroomAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Maitake Mushroom + Acebutolol interactionReishi MushroomAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mushroom + Acebutolol interactionCilantroAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Cilantro + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Reishi MushroomAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
NdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acepromazine interactionCilantroPhotosensitizing Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Aspirin interactionReishi MushroomAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Reishi MushroomAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mushroom + Acetaminophen, Aspirin, Caffeine interactionMilk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
CilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionMilk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Milk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Butalbital, Caffeine, Codeine interactionCilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Butalbital, Codeine interactionCilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
CilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Butalbital, Codeine Phosphate interactionMilk ThistleGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCilantroCns Depressants, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Caffeine, Codeine interactionCilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
CilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Caffeine, Codeine, Salicylamide interactionMilk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Belly Mend — through 2 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Caffeine, Dihydrocodeine interactionCilantroCns Depressants Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Milk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Belly Mend — through 1 ingredient. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
CilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionMilk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCilantroCns Depressants, Photosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
NdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionMilk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
CilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionMilk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
NdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionMilk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Milk ThistleCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
It is unclear if milk thistle inhibits CYP3A4; research is conflicting.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
Milk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Phenylephrine interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Phenylephrine interactionNdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Belly Mend — through 3 ingredients. Tap an ingredient for the detail:
NdfPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, chlorella might have additive effects with photosensitizing drugs.
Read the full Ndf + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionMilk ThistleGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.
Read the full Milk Thistle + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionCilantroPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Read the full Cilantro + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Belly Mend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
CytoFlora Probiotics Lystates
Antibiotic Drugs
Theoretically, taking antibiotic drugs with certain probiotics might decrease the effectiveness of probiotics.
Many probiotics are bacteria. Since these preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of sensitive organisms. Human research shows that taking probiotic concurrently with antibiotic treatment does not affect the diversity of the gut microbiome compared with antibiotic treatment in the absence of probiotics. Tell patients to separate administration of antibiotics and these preparations by at least two hours.
Antifungals
Theoretically, taking antifungals with certain probiotics might decrease the effectiveness of probiotics.
Some probiotics such as Saccharomyces boulardii are fungi. Therefore, simultaneously taking antifungals might kill a significant number of these organisms.
Brand information
Manufacturer and brand details for Belly Mend, from the product label.
Bioray
See all Bioray products- Name
- BioRay Inc.
- City
- Irvine
- State
- CA
- ZipCode
- 92618
- Phone Number
- (888) 635-9582
- Web Address
- bioray.com
Belly Mend by Bioray: Common Questions
Does Belly Mend by Bioray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Do I need to separate this product from my antibiotics?
Can I take this if I'm on warfarin or other blood thinners?
Is it safe to use while pregnant or breastfeeding?
What are the probiotics supposed to do?
Can I take this if I have diabetes?
Is chlorella (NDF) in this product safe?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Belly Mend is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Belly Mend’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Belly Mend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 264 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Lactobacillus Helveticus 2 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
See these in context on the Lactobacillus Helveticus monograph →
Olive 2 references
- Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
- Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
- Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
- Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
- Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
- Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
- Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
- Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
- Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
- Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
- Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
- Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.
Milk Thistle 69 references
- Ferenci P, Dragosics B, Dittrich H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol 1989;9:105-13. PubMed
- Anon. Milk thistle: Effects on liver disease and cirrhosis and clinical adverse effects. Summary, Evidence Report/Technology Assessment: Number 21, September 2000. Agency for Healthcare Research and Quality, Rockville, MD. Available at: http://www.ahrq.g
- Beckmann-Knopp S, Rietbrock S, Weyhenmeyer R, et al. Inhibitory effects of silibinin on cytochrome P-450 enzymes in human liver microsomes. Pharmacol Toxicol 2000;86:250-6. PubMed
- Venkataramanan R, Ramachandran V, Komoroski BJ, et al. Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures. Drug Metab Dispos 2000;28:1270-3. DOI
- Kim DH, Jin YH, Park JB, Kobashi K. Silymarin and its components are inhibitors of beta-glucuronidase. Biol Pharm Bull 1994;17:443-5. PubMed
- Pares A, Planas R, Torres M, et al. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. J Hepatol 1998;28:615-21. PubMed
- Piscitelli SC, Formentini E, Burstein AH, et al. Effect of milk thistle on the pharmacokinetics of indinavir in healthy volunteers. Pharmacotherapy 2002;22:551-6. PubMed
- Boerth J, Strong KM. The clinical utility of milk thistle (Silybum marianum) in cirrhosis of the liver. J Herb Pharmacother 2002;2:11-7.
- Tanamly MD, Tadros F, Labeeb S, et al. Randomised double-blinded trial evaluating silymarin for chronic hepatitis C in an Egyptian village: study description and 12-month results. Dig Liver Dis 2004;36:752-9. PubMed
- Gurley BJ, Gardner SF, Hubbard MA, et al. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clin Pharmacol Ther 2004;76:428-40. .
- Huseini HF, Larijani B, Heshmat R, et al. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. Phytother Res 2006;20;1036-9.
- Deng JW, Shon JH, Shin HJ, et al. Effect of silymarin supplement on the pharmacokinetics of rosuvastatin. Pharm Res 2008;25:1807-14. PubMed
- Kim CS, Choi SJ, Park CY, et al. Effects of silybinin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen in rats. Anticancer Res 2010;30:79-85.
- Sridar C, Goosen TC, Kent UM, et al. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases. Drug Metab Dispos 2004;32:587-94. PubMed
- van Erp NP, Baker SD, Zhao M, et al. Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan. Clin Cancer Res 2005;11:7800-6.
- Budzinski JW, Trudeau VL, Drouin CE, et al. Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products. Can J Physiol Pharmacol 2007;85:966-78.
- Doehmer J, Weiss G, McGregor GP, Appel K. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities. Toxicol In Vitro 2011;25:21-7. PubMed
- Jiao Z, Shi XJ, Li ZD, et al. Population pharmacokinetics of sirolimus in de novo Chinese adult renal transplant patients. Br.J.Clin.Pharmacol. 2009;68(1):47-60.
- Gurley, B. J., Barone, G. W., Williams, D. K., Carrier, J., Breen, P., Yates, C. R., Song, P. F., Hubbard, M. A., Tong, Y., and Cheboyina, S. Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin phar
- Allain, H., Schuck, S., Lebreton, S., Strenge-Hesse, A., Braun, W., Gandon, J. M., and Brissot, P. Aminotransferase levels and silymarin in de novo tacrine-treated patients with Alzheimer's disease. Dement.Geriatr.Cogn Disord. 1999;10(3):181-185. PubMed
- Angulo, P., Patel, T., Jorgensen, R. A., Therneau, T. M., and Lindor, K. D. Silymarin in the treatment of patients with primary biliary cirrhosis with a suboptimal response to ursodeoxycholic acid. Hepatology 2000;32(5):897-900. PubMed
- Bean, P. The use of alternative medicine in the treatment of hepatitis C. Am.Clin.Lab 2002;21(4):19-21.
- Hussain, S. A. Silymarin as an adjunct to glibenclamide therapy improves long-term and postprandial glycemic control and body mass index in type 2 diabetes. J.Med.Food 2007;10(3):543-547. PubMed
- El-Kamary, S. S., Shardell, M. D., Abdel-Hamid, M., Ismail, S., El-Ateek, M., Metwally, M., Mikhail, N., Hashem, M., Mousa, A., Aboul-Fotouh, A., El-Kassas, M., Esmat, G., and Strickland, G. T. A randomized controlled trial to assess the safety and effic
- Gharagozloo, M., Moayedi, B., Zakerinia, M., Hamidi, M., Karimi, M., Maracy, M., and Amirghofran, Z. Combined therapy of silymarin and desferrioxamine in patients with beta-thalassemia major: a randomized double-blind clinical trial. Fundam.Clin.Pharmaco
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Agaricus Mushroom 5 references
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Turkey Tail Mushroom 15 references
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See these in context on the Turkey Tail Mushroom monograph →
Maitake Mushroom 8 references
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