Interactions on record — worth a quick check against your medications. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Boswellia 3K Ingredients & Drug Interactions

by True Botanica

Boswellia 3K label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Boswellia 3K against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Boswellia 3K is a dietary supplement by True Botanica with 7 active ingredients. Its ingredients are commonly taken for flavoring and culinary use, digestive complaints like bloating and indigestion, boosting absorption of other supplements.Based on those ingredients, 1,138 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioperine Nature's Thermonutrient, Boswellin PS, Myrrh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Boswellia 3K by True Botanica

Ask about any prescription or over-the-counter medication and we check it for interactions with Boswellia 3K by True Botanica — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Boswellia 3K by True Botanica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 7 active ingredients.
  • “Bioperine Nature's Thermonutrient” is listed as a grouped ingredient — the label gives one combined amount (1 mg) without saying how much of each component you get.
  • “AKBA 90” is listed as a grouped ingredient — the label gives one combined amount (60 mg) without saying how much of each component you get.
  • “Boswellia 3K Pentas Mix” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

Boswellia 3K contains 7 active ingredients. The main one is Boswellia serrata, a tree resin traditionally used for joint and inflammatory concerns.

It also includes myrrh, another resin with a long history in traditional medicine. The product contains several proprietary blends and concentrated extracts — AKBA 90, Boswellin PS, 3-O-acetyl-11-keto-beta-boswellic acid, and Boswellia 3K Pentas Mix — which are meant to standardize or concentrate specific compounds from boswellia.

Bioperine (a black pepper extract) is included to potentially enhance absorption. The capsules also hold inactive ingredients: inulin, cellulose, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Joint pain and inflammation support.
  • We looked for evidence on: Osteoarthritis, Rheumatoid arthritis (RA), Back pain, Knee pain, Herniated disc, Sciatica — and 4 related terms.
  • The strongest evidence on file: Boswellia Serrata is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Boswellia Serrata is rated "Insufficient Reliable Evidence To Rate" for Asthma, Crohn disease, Ulcerative colitis, Irritable bowel syndrome (IBS), and more.

The evidence for Boswellia 3K's main ingredient, Boswellia serrata, is mixed. It's rated possibly effective for osteoarthritis — that's the strongest claim we have.

For allergic rhinitis (hay fever), asthma, Alzheimer disease, and cluster headache, the evidence isn't established in our data. As for myrrh, the effectiveness data we hold shows it's likely ineffective for schistosomiasis; for back pain, cancer, the common cold, dental issues, and Crohn disease, we have insufficient evidence to rate it one way or the other.

The evidence, ingredient by ingredient Black Pepper Boswellia Serrata Myrrh

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Boswellia serrata is generally well tolerated in the short term, though quality and dose vary widely between products. The most common side effects are mild: abdominal pain, diarrhea, headache, heartburn, itching, and nausea.

In one study, nearly 11% of people reported headache. A rare serious concern is that very large amounts of boswellia gum resin can form a bezoar (a blockage in the gut).

Myrrh's oral safety isn't well studied — topically it's been reported to cause dermatitis, and orally it may cause diarrhea at higher doses. Regarding pregnancy: Boswellia serrata is rated likely safe, but myrrh should be avoided during pregnancy because it's traditionally believed to stimulate the uterus and has caused severe abdominal pain in a pregnant woman.

For breastfeeding, Boswellia serrata safety data isn't on file, and myrrh should be avoided due to insufficient safety information.

Side effects, ingredient by ingredient Black Pepper Boswellia Serrata Myrrh

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Boswellia Serrata, Myrrh, Black Pepper.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,139 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Boswellia 3K, check your medications in the search tool below. The main concerns are drugs broken down by liver enzymes (CYP2D6, CYP2C19, CYP1A2, CYP2C9, CYP3A4 substrates), which may build up to higher levels; diabetes medications, due to myrrh's potential blood-sugar-lowering effect; and warfarin, which myrrh may weaken.

If you take any of these drug types, talk to your pharmacist before adding this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Boswellia 3K may be worth considering if you have osteoarthritis and want to explore botanical options, but the enzyme interactions are significant — talk to your pharmacist before starting, especially if you take any prescription medications. Myrrh interactions also matter if you're on diabetes drugs or warfarin.

Avoid this product if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Boswellia 3K, straight from the product label.

Brand True Botanica
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336209
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Boswellia 3K by True Botanica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Gold0 NP--
Boswellia serrata0 NP--
Bioperine Nature's Thermonutrient1 mg--
Myrrh0 NP--
Piperine0.95 mg--
AKBA 9060 mg--
Boswellin PS60 mg--
3-O-Acetyl-11-Keto-{Beta}-Boswellic Acid54 mg--
Boswellia 3K Pentas Mix10 mg--
Amber0 NP--

Other ingredients: Inulin, Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Contains the most full spectrum frankincense (boswellia) resin. It has the highest concentration of its most active component AKBA (90% AKBA as opposed to 2-3% AKBA normally available in other preparations)! Bioperine and rhythmically prepared myrrh and gold added to increase bioavailability and overall effectiveness.

Formulation

Contains no milk, eggs, fish, Crustacean shellfish, tree nuts, peanuts, wheat, sesame, or soybeans. Gluten free.

Vegetarian capsules.

Ultra-concentrated

Precautions

Consult your health care provider before using this product if you are pregnant, lactating or have other medical concerns or compatibility issues.

Do not use this product if allergies to the listed ingredients are known to exist or if any adverse effects result after taking the first dose.

This product contains a desiccant package, which should not be eaten.

Keep out of the reach of children.

Storage

Keep desiccant in the bottle until all tablets have been taken.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested usage: One capsule three times daily, or as suggested by your health care provider.

Brand IP Statement(s)

Bioperine is a patented product from Sabinsa Corporation. U.S. Patents #5,536,506; 5,744,161; 5,972, 382; & 6,054,585. Boswellin is a registered trademark of Sabinsa Corporation.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Boswellia 3K by True Botanica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Boswellia 3K label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Boswellia 3K by True Botanica

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bioperine Nature's Thermonutrient

Interacts with
1,019 drugs
1 mg per serving Form: Piper nigrum

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to he...

Bioperine Nature's Thermonutrient monograph & interactions

AKBA 90

60 mg per serving Form: Boswellia serrata
  • › 3-O-Acetyl-11-Keto-{Beta}-Boswellic Acid

Boswellin PS

Interacts with
952 drugs
60 mg per serving Form: Boswellia serrata

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

Boswellin PS monograph & interactions

Boswellia 3K Pentas Mix

10 mg per serving

Other (inactive) ingredients: Inulin, Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Boswellia 3K by True Botanica Drug Interactions

Want to check YOUR meds against Boswellia 3K?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,138Drugs
1,136 Moderate 2 Minor

Ingredients driving the most interactions

Bioperine Nature's Thermonutrient 1,019
Boswellin PS 952
Myrrh 88

Individual Drug Interactions

The ingredients in Boswellia 3K interact with 1,138 drugs. Click any drug to see the details.

3 of the 7 ingredients in Boswellia 3K interact with drugs. Each result below shows which ingredient is responsible. Bioperine Nature's Thermonutrient Boswellin PS Myrrh

Each ingredient & the kinds of drugs it affects

For each ingredient in Boswellia 3K with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioperine Nature's Thermonutrient17 drug types · 1,019 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation. This has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, black pepper might increase blood levels of atorvastatin.
Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold. This has not been reported in humans.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, black pepper might increase the effects and side effects of cyclosporine.
In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
In vitro research suggests that some constituents of black pepper inhibit CYP2D6. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
In vitro research and pharmacokinetic simulation data suggest that piperine, a constituent of black pepper, as well as the pepper fruit seem to inhibit CYP3A4. This has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
Black pepper is thought to have diuretic properties.

Likelihood Probable Evidence D
Nevirapine (Viramune)

Black pepper might increase blood levels of nevirapine.
Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study.

Likelihood Probable Evidence D
P-Glycoprotein Substrates

Theoretically, black pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, black pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Black pepper might increase blood levels of phenytoin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin. Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin. Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper.

Likelihood Possible Evidence B
Propranolol (Inderal)

Black pepper might increase blood levels of propranolol.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Black pepper might increase blood levels of rifampin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence B
Theophylline

Black pepper might increase blood levels of theophylline.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline.

Likelihood Possible Evidence D
Amoxicillin (Amoxil, Trimox)

Theoretically, black pepper might increase the effects and side effects of amoxicillin.
Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin. This has not been reported in humans.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects. In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that black pepper induces CYP1A2. This has not been reported in humans.

Likelihood Possible Evidence D
Bioperine Nature's Thermonutrient full monograph & interactions

Boswellin PS6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
Boswellin PS full monograph & interactions

Myrrh2 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.

Likelihood Possible Evidence D
Myrrh full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Boswellia 3K, from the product label.

True Botanica

See all True Botanica products
Name
True Botanica, LLC
Street Address
1005 Richards Road, Suite D
City
Hartland
State
WI
ZipCode
53029
Phone Number
1-800-315-8783
Web Address
www.truebotanica.com
Pharmacist Counseling Corner

Boswellia 3K by True Botanica: Common Questions

Does Boswellia 3K by True Botanica interact with any medications?
Yes. Based on its ingredients, Boswellia 3K has a known interaction with 1,138 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Boswellia 3K contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Boswellia 3K safe during pregnancy or while breastfeeding?
Boswellia serrata itself is rated likely safe in pregnancy. However, the myrrh in this product should be avoided during pregnancy — it's traditionally believed to stimulate the uterus and has caused severe abdominal pain in at least one pregnant woman. For breastfeeding, there isn't enough safety data on either ingredient. Talk with your doctor or pharmacist before using this product if you're pregnant or nursing.
What side effects might I experience?
The most common ones from Boswellia serrata are mild: abdominal pain, diarrhea, headache, heartburn, nausea, and itching. In one study, nearly 11% of people reported headache. Myrrh may cause diarrhea at higher doses. A rare but serious concern with very large amounts of boswellia is bezoar formation (a blockage in the stomach or intestines).
Does this product actually work for arthritis?
Boswellia serrata is rated possibly effective for osteoarthritis — that's the strongest evidence we have for any condition in this product. For other uses like allergic rhinitis, asthma, or Alzheimer disease, the evidence isn't established in our data.
Why are there so many ingredient names I don't recognize?
Several of them — AKBA 90, Boswellin PS, 3-O-acetyl-11-keto-beta-boswellic acid, and Boswellia 3K Pentas Mix — are concentrated or standardized extracts from boswellia designed to isolate specific active compounds. They're meant to make the dose more consistent and potent than whole plant material alone.
Can I check whether this interacts with my medications?
Yes — use the medication checker on this page to search your exact prescriptions. The main concerns are liver-enzyme-dependent drugs, diabetes medications, and blood thinners like warfarin, but the interaction database covers over 1,000 individual medications that may be affected by the ingredients in this product.
What does Bioperine do in this formula?
Bioperine is a black pepper extract included to potentially enhance how your body absorbs the other ingredients, though we don't hold interaction data on it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Boswellia 3K label
Go deeper

The Full Monographs Behind Boswellia 3K’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Pepper

Interacts with 1,019 drugs

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to help the body absorb other ingredients (li...

Read the full Black Pepper monograph → Herb & supplement monograph

Boswellia Serrata

Interacts with 952 drugs

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...

Read the full Boswellia Serrata monograph → Herb & supplement monograph

Myrrh

Interacts with 88 drugs

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...

Read the full Myrrh monograph →
Sources

Sources & How We Checked

Boswellia 3K's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 53 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
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Black Pepper 29 references
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  9. Munakata, M., Kobayashi, K., Niisato-Nezu, J., Tanaka, S., Kakisaka, Y., Ebihara, T., Ebihara, S., Haginoya, K., Tsuchiya, S., and Onuma, A. Olfactory stimulation using black pepper oil facilitates oral feeding in pediatric patients receiving long-term en
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Myrrh 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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  8. Al-Romaiyan A, Huang GC, Jones P, Persaud S. Commiphora myrrha stimulates insulin secretion from mouse and human islets of Langerhans. J Ethnopharmacol. 2021 Jan 10;264:113075. PubMed

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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