Brahmi Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Brahmi against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Brahmi is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 930 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Brahmi Whole Herb Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Brahmi by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Brahmi by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Brahmi by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: Brahmi Whole Herb Extract, Dry (bacopa). Bacopa is used in traditional medicine for cognition and memory support.
The liquid also contains alcohol, water, and glycerin as inactive ingredients that help deliver and preserve the extract.
Does it work?
Not established
The evidence for bacopa isn't established in our data. We hold insufficient reliable evidence to rate it for Alzheimer disease, sexual dysfunction, ADHD, back pain, or cognitive function and impairment.
If you're considering it for one of these uses, talk with your pharmacist or doctor about whether the current research supports it for your situation.
How safe is it?
Well-documented data
Bacopa is generally well tolerated in studies, though quality and long-term safety data are limited. The most common side effects are abdominal cramps, diarrhea, dry mouth, headache, and nausea.
Some people report drowsiness, insomnia, or vivid dreams. Gastrointestinal complaints (cramping, bloating, diarrhea, nausea, and appetite changes) show up in 12% to 30% of study participants.
There isn't enough safety information to know whether bacopa is safe in pregnancy or while breastfeeding — the data advises against it during both. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
Moderate interaction found
Before you take Brahmi, check if you're on any medications broken down by your liver's CYP1A2, CYP2C9, CYP2C19, or CYP3A4 enzymes — bacopa might slow that process (Moderate severity). Also flag cholinergic drugs (those that boost acetylcholine, like cevimeline), anticholinergic drugs, or thyroid hormone.
Use the search tool on this page to verify your specific medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Brahmi may be worth considering if you're interested in traditional cognitive support and your medications don't overlap with the ones bacopa affects. Anyone taking medications processed through your liver, cholinergic drugs, anticholinergic drugs, or thyroid hormone should double-check with us first.
If you have a history of gastrointestinal problems or are pregnant or breastfeeding, talk with your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Brahmi, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7386004867942 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2024 |
| DSLD ID | 324847 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Brahmi by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Brahmi Whole Herb Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Bacopa monnieri
Organic alcohol
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Brahmi by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Brahmi by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Brahmi Whole Herb Extract, Dry
Interacts with930 drugs
Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...
Brahmi Whole Herb Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Brahmi by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Brahmi by Herbal Terra contains bacopa, which has moderate interactions with several medication categories that work through your liver's drug-processing system.
The most serious concern is with medications broken down by cytochrome P450 enzymes (CYP1A2, CYP2C9, CYP2C19, and CYP3A4 substrates) — bacopa might slow how your liver clears these drugs, raising their levels and risk of side effects. The research here is mixed; some lab studies show bacopa can inhibit these enzymes, while others suggest any real-world effect is unlikely.
Read the full breakdown — every affected drug type, severity by severity
Bacopa also interacts with cholinergic drugs (medications that boost acetylcholine, a brain chemical) — it may add to their effects. On the flip side, anticholinergic drugs (which block acetylcholine) could work against bacopa, and bacopa could work against them.
There's a documented case of one person taking cevimeline (a cholinergic drug for dry mouth in Sjögren syndrome) who experienced sweating, nausea, fast heartbeat, and general malaise shortly after a single dose of bacopa; symptoms cleared within two days. Bacopa may also have minor additive effects with thyroid hormone.
Altogether, these interactions span 919 individual medications. Check your exact prescriptions with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Brahmi?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Brahmi interact with 930 drugs. Click any drug to see the details.
1 of the 1 ingredient in Brahmi interact with drugs. Each result below shows which ingredient is responsible. Brahmi Whole Herb Extract, Dry
Acetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Read the full Brahmi Whole Herb Extract, Dry + Acetylcholine interactionAclidinium BromideTudorza Pressair
How Aclidinium Bromide interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Whole Herb Extract, Dry + Aclidinium Bromide interactionAclidinium Bromide, Formoterol Fumarate DihydrateDuaklir Pressair
How Aclidinium Bromide, Formoterol Fumarate Dihydrate interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Whole Herb Extract, Dry + Aclidinium Bromide, Formoterol Fumarate Dihydrate interactionAdagrasibKrazati
How Adagrasib interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Agomelatine interactionAlfentanilAlfenta
How Alfentanil interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Alprazolam interactionAmantadineGocovri, Osmolex ER, Symmetrel
How Amantadine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Whole Herb Extract, Dry + Amantadine interactionAmbenonium ChlorideMytelase
How Ambenonium Chloride interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Read the full Brahmi Whole Herb Extract, Dry + Ambenonium Chloride interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Brahmi Whole Herb Extract, Dry + Ambrisentan interactionAmifampridineRuzurgi
How Amifampridine interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Read the full Brahmi Whole Herb Extract, Dry + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryCholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Read the full Brahmi Whole Herb Extract, Dry + Amifampridine Phosphate interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Brahmi — through 1 ingredient. Tap an ingredient for the detail:
Brahmi Whole Herb Extract, DryAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, concurrent use might decrease the effectiveness of both agents.
Read the full Brahmi Whole Herb Extract, Dry + Aminoglutethimide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Brahmi with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brahmi Whole Herb Extract, Dry
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Brand information
Manufacturer and brand details for Brahmi, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Brahmi by Herbal Terra: Common Questions
Does Brahmi by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is bacopa, and what's it supposed to do?
Does bacopa actually work for memory or brain function?
What side effects might I notice?
Is bacopa safe to use while I'm pregnant or breastfeeding?
Why does this product interact with so many medications?
What's in this liquid besides the bacopa extract?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Brahmi is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Brahmi’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Brahmi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacopa 12 references
- Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
- Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
- Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
- Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
- Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
- Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
- Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
- Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
- Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
- Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.
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