Calming Ingredients & Drug Interactions
by Yogi
What is this page for?
First and foremost: checking Calming against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Calming is a dietary supplement by Yogi with 10 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation and calming.Based on those ingredients, 1,333 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Licorice, organic Fennel, organic Lemongrass. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Calming by Yogi
Ask about any prescription or over-the-counter medication and we check it for interactions with Calming by Yogi — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Calming by Yogi
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 10 active ingredients.
- “Proprietary Blend of Herbs” is a proprietary blend — the label gives one combined amount (1,727 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 5 of the 6 matched ingredients can interact with medications — Fennel, Lemongrass, Gotu Kola, Lavender, Licorice.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
- For scale: 1,334 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 6 of 6.
- General safety write-ups exist for 6 of 6.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Calming, straight from the product label.
| Brand | Yogi |
|---|---|
| Barcode (UPC) | 076950450028 |
| Net contents | 16 Tea Bag(s); 1.02 Oz(s); 29 Gram(s) |
| Market status | Off market |
| Date entered into DSLD | Apr 25, 2017 |
| DSLD ID | 73032 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Calming by Yogi, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| organic Chamomile | 0 NP | -- |
| Proprietary Blend of Herbs | 1727 mg | -- |
| organic Orange | 0 NP | -- |
| organic Rose Hip | 0 NP | -- |
| organic Lavender | 0 NP | -- |
| organic Licorice | 0 NP | -- |
| organic Cardamom | 0 NP | -- |
| organic Lemongrass | 0 NP | -- |
| organic Hibiscus | 0 NP | -- |
| organic Gotu Kola | 0 NP | -- |
| organic Fennel | 0 NP | -- |
Other ingredients: organic toasted Brown Rice, natural Plum flavor, organic Brown Rice flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Love our tea as much as we do or we’ll gladly refund your money. Inspire us and yourself
- Recyclable - Non-irradiated - Oxygen-bleached tea bags Please recycle this box.
Our Calming tea is an exclusive blend based on time-honored Ayurvedic herbs that can help soothe stress and tension, and encourage a state of relaxation.
So sit back and relax with a delicious and soothing cup of Yogi Calming tea - and discover a soothing, natural way to find calm, any time of day.
To help protect our forests and reduce landfill burden, Yogi tea cartons use 100% Recycled Paperboard, 55% post consumer waste, and are printed with environmentally-friendly vegetable-based inks.
Eases mild tension
Yoga for serenity Sit cross-legged or in a chair with spine straight and feet flat. Now, close your eyes and block right nostril with right hand. Take deep, slow breaths through the left nostril. Continue for 1 to 3 minutes. Let the positive and relaxing feeling take over. Before doing this exercise or participating in any exercise program, consult your physician.
Our story began in 1969 when Yogi Bhajan, an inspirational teacher of holistic living, started teaching yoga in the west. He shared with his students his wisdom and knowledge of healthy living and the beneficial properties of herbs, all while serving a comforting and aromatic spiced tea they affectionately named “Yogi Tea”.
Recyclable Compostable tea bags
Brand IP Statement(s)
2014 East West Tea Company, LLC
Find Serenity with Yogi Calming Tea
100% recycled paperboard
Suggested/Recommended/Usage/Directions
Get the most out of every cup Bring water to boiling and steep 5 to 10 minutes. For a stronger tea, use 2 tea bags. Enjoy 2 to 4 cups a day.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
This organic tea combines chamomile - traditionally used by herbalists to help compose the mind and relax the body - with lemongrass and gotu kola. Organic lavender flower and licorice add a pleasant, naturally sweet flavor.
Circle U
General
30766-G4 D730 201866
Formulation
Caffeine free
USDA organic
V vegan
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
USDA organic
V vegan
Certified circle B corporation
Circle U
Quality assurance international Certified organic
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Calming by Yogi label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Calming by Yogi
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend of Herbs
- › Organic Chamomile
- › Organic Orange
- › Organic Rose Hip
- › Organic Lavender
- › Organic Licorice
- › Organic Cardamom
- › Organic Lemongrass
- › Organic Hibiscus
- › Organic Gotu Kola
- › Organic Fennel
Other (inactive) ingredients: Organic toasted Brown Rice, Natural Plum flavor, Organic Brown Rice flavor. These complete the product’s ingredient list but are not active constituents.
Calming by Yogi Drug Interactions
Calming contains 10 ingredients, and 5 of them have known drug interactions. Altogether they interact with 1,333 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Calming?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Calming interact with 1,333 drugs. Click any drug to see the details.
5 of the 10 ingredients in Calming interact with drugs. Each result below shows which ingredient is responsible. organic Licorice organic Fennel organic Lemongrass organic Gotu Kola organic Lavender
AlmotriptanAlmogran, Axert
How Almotriptan interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Almotriptan interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Almotriptan interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Calming — through 4 ingredients. Tap an ingredient for the detail:
Organic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Alogliptin interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Alogliptin interactionOrganic LicoriceCytochrome P450 2c8 (cyp2c8) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
Read the full Organic Licorice + Alogliptin interactionOrganic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Calming — through 4 ingredients. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Alogliptin, Pioglitazone interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Alogliptin, Pioglitazone interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Alogliptin, Pioglitazone interactionOrganic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c8 (cyp2c8) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Alpelisib interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Alpelisib interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Calming — through 5 ingredients. Tap an ingredient for the detail:
Organic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Alprazolam interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Alprazolam interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Alprazolam interactionOrganic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Alprazolam interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Organic Fennel + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Organic Fennel + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Organic Fennel + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAlvimopanEntereg
How Alvimopan interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic LicoriceP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
Read the full Organic Licorice + Alvimopan interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Calming — through 4 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates +1 Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Ambrisentan interactionOrganic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Ambrisentan interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Ambrisentan interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic LicoriceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic LicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Calming — through 2 ingredients. Tap an ingredient for the detail:
Organic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Aminoglutethimide interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Calming — through 2 ingredients. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Aminophylline, Amobarbital, Ephedrine interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Aminophylline, Amobarbital, Ephedrine interactionAminosalicylic AcidPaser
How Aminosalicylic Acid interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Aminosalicylic Acid interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Calming — through 4 ingredients. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Amiodarone interactionOrganic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c8 (cyp2c8) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Amiodarone interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amiodarone interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Calming — through 5 ingredients. Tap an ingredient for the detail:
Organic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amitriptyline interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amitriptyline interactionOrganic LicoriceCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
Read the full Organic Licorice + Amitriptyline interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amitriptyline interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Calming — through 5 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Organic Licorice + Amitriptyline, Chlordiazepoxide interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amitriptyline, Chlordiazepoxide interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amitriptyline, Chlordiazepoxide interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amitriptyline, Chlordiazepoxide interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Calming — through 5 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
Read the full Organic Licorice + Amitriptyline, Perphenazine interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amitriptyline, Perphenazine interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amitriptyline, Perphenazine interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amitriptyline, Perphenazine interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine interactionOrganic LicoriceAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Amlodipine Benzoate interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine Benzoate interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LicoriceAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Amlodipine Besilate interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine Besilate interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine Besylate interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine Besylate interactionOrganic LicoriceAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Amlodipine Besylate, Benazepril interactionOrganic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine Besylate, Benazepril interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LemongrassCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Read the full Organic Lemongrass + Amlodipine, Celecoxib interactionOrganic FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Organic Fennel + Amlodipine, Celecoxib interactionOrganic LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs +1 Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Organic Licorice + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic LicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Organic Licorice + Ammonium Chloride interactionAmobarbitalAmytal
How Amobarbital interacts with Calming — through 2 ingredients. Tap an ingredient for the detail:
Organic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amobarbital interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Calming — through 2 ingredients. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amobarbital, Ephedrine Sulfate interactionOrganic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Calming — through 3 ingredients. Tap an ingredient for the detail:
Organic LavenderCns Depressants Moderate
Interaction Summary
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Read the full Organic Lavender + Amobarbital, Secobarbital interactionOrganic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Amobarbital, Secobarbital interactionOrganic LicoriceCytochrome P450 2b6 (cyp2b6) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
Read the full Organic Licorice + Amobarbital, Secobarbital interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Calming — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Amoxicillin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Calming with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Licorice
Antihypertensive Drugs
Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.
Cisplatin (Platinol-Aq)
Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.
Corticosteroids
Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.
Digoxin (Lanoxin)
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Diuretic Drugs
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.
Estrogens
Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.
Loop Diuretics
Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.
Midazolam (Versed)
Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.
P-Glycoprotein Substrates
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.
Paclitaxel (Abraxane, Onxol)
Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.
Warfarin (Coumadin)
Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.
Methotrexate (Trexall, Others)
Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.
organic Fennel
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
organic Lemongrass
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, lemongrass might decrease the metabolism of CYP3A4 substrates.
Animal research shows that lemongrass and its constituent citral inhibit CYP3A4.
Glucuronidated Drugs
Theoretically, lemongrass might increase the clearance and decrease the levels of glucuronidated drugs.
Animal research shows that lemongrass and its constituent citral induce uridine diphosphoglucuronosyl transferase (UGT), the major phase 2 enzyme that is responsible for glucuronidation.
Pentobarbital (Nembutal)
Theoretically, lemongrass might increase the effects and adverse effects of pentobarbital.
Animal research shows that high doses of lemongrass essential oil increases sleep time and decreases time to fall asleep in animals administered pentobarbital.
organic Gotu Kola
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
organic Lavender
Cns Depressants
Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Laboratory research suggests that lavender has sedative effects. However, clinical studies in patients taking oral lavender oil (Silexan) 160 mg for 10 weeks or taking lavender flower powder 1 gram daily for 2 months have not reported side effects of drowsiness, sedation, or sleepiness. There is still some concern that higher doses or different preparations of lavender might have additive effects with CNS depressant medications.
Brand information
Manufacturer and brand details for Calming, from the product label.
Yogi
See all Yogi products- Name
- YOGI A product of East West Tea Company, LLC
- Street Address
- 950 International Way
- City
- Springfield
- State
- OR
- ZipCode
- 97477
- Web Address
- www.yogiproducts.com
Calming by Yogi: Common Questions
Does Calming by Yogi interact with any medications?
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Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Calming’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lavender
Interacts with 248 drugsLavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for a standardized oral lavender oil product for anxie...
Read the full Lavender monograph → Herb & supplement monographLicorice
Interacts with 1,040 drugsLicorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...
Read the full Licorice monograph → Herb & supplement monographCardamom
Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements...
Read the full Cardamom monograph → Herb & supplement monographLemongrass
Interacts with 708 drugsLemongrass is a fragrant tropical grass widely used as a cooking herb, a tea, and an aromatherapy oil. It is generally considered safe in the small amounts used in food, but most of its clai...
Read the full Lemongrass monograph → Herb & supplement monographGotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph → Herb & supplement monographFennel
Interacts with 740 drugsFennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...
Read the full Fennel monograph →Sources & How We Checked
Calming's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 151 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lavender 20 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:123-7. PubMed
- Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10.
- Coulson IH and Khan AS. Facial 'pillow' dermatitis due to lavender oil allergy. Contact Dermatitis 1999;41(2):111. PubMed
- Woelk, H. and Schlafke, S. A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010;17(2):94-99. PubMed
- Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, plac
- Uehleke, B., Schaper, S., Dienel, A., Schlaefke, S., and Stange, R. Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine. 6-15-2012;19(8-9):665-671. PubMed
- Brandao FM. Occupational allergy to lavender oil. Contact Dermatitis 1986;15(4):249-250. PubMed
- Rademaker M. Allergic contact dermatitis from lavender fragrance in Difflam gel. Contact Dermatitis 1994;31(1):58-59. PubMed
- Kasper S, Gastpar M, Müller WE, et al. Lavender oil preparation Silexan is effective in generalized anxiety disorder--a randomized, double-blind comparison to placebo and paroxetine. Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69. PubMed
- Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract 2018;31:132-8. PubMed
- Bingham LJ, Tam MM, Palmer AM, Cahill JL, Nixon RL. Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic. Contact Dermatitis. 2019;81(1):37-42. PubMed
- Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019;65:153099. PubMed
- Firoozeei TS, Feizi A, Rezaeizadeh H, Zargaran A, Roohafza HR, Karimi M. The antidepressant effects of lavender (Lavandula angustifolia Mill.): A systematic review and meta-analysis of randomized controlled clinical trials. Complement Ther Med 2021;59:102 PubMed
- Kodama T, Watanabe T, Mataki N, Kanoh S, Kichikawa Y. Acute eosinophilic pneumonia following aromatherapy with essential oil. Respir Med Case Rep 2022;37:101657. PubMed
- Barbaud A, Kurihara F, Raison-Peyron N, et al. Allergic contact dermatitis from essential oil in consumer products: Mode of uses and value of patch-tests with an essential oil series. Results of a French study of the DAG (dermato-allergy group of the Fren
- Ozer H, Sayan ZA, Baloglu I, Ozturk Y, Yonet F, Turkmen K. Unknown criminals for kidney: Acute interstitial nephritis due to lavender tea. Explore (NY) 2023. PubMed
- Kasper S, Volz HP, Möller HJ, et al. Lavender oil preparation Silexan is effective in mild-to-moderate major depression: a randomized, placebo- and reference-controlled trial. Eur Arch Psychiatry Clin Neurosci 2024. PubMed
- Simaei SR, Askari VR, Rostami M, et al. Lavender and metformin effectively propagate progesterone levels in patients with polycystic ovary syndrome: A randomized, double-blind clinical trial. Fitoterapia 2023;172:105720. PubMed
Licorice 92 references
- Farese RV Jr, Biglieri EG, Shackleton CH, et al. Licorice-induced hypermineralocorticoidism. N Engl J Med 1991;325:1223-7. PubMed
- Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? J Hum Hypertens 1995;9:345-8.
- Armanini D, Lewicka S, Pratesi C, et al. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. J Endocrinol Invest 1996;19:624-9. PubMed
- Zhang YD, Lorenzo B, Reidenberg MM. Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. J Steroid Biochem Mol Biol 1994;49:81-5.
- Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Birth outcome in relation to licorice consumption during pregnancy. Am J Epidemiol 2001;153:1085-8. PubMed
- Sigurjonsdottir HA, Franzson L, Manhem K, et al. Liquorice-induced rise in blood pressure: a linear dose-response relationship. J Hum Hypertens 2001;15:549-52. PubMed
- Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
- Kent UM, Aviram M, Rosenblat M, Hollenberg PF. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Drug Metab Dispos 2002;30:709-15.. PubMed
- Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Clin Neurol Neurosurg 2003;105:286-7.. PubMed
- Strandberg TE, Andersson S, Jarvenpaa AL, et al. Preterm birth and licorice consumption during pregnancy. Am J Epidemiol 2002;156:803-5.. PubMed
- Hussain RM. The sweet cake that reaches parts other cakes can't! Postgrad Med J 2003;79:115-6.. PubMed
- Morris DJ, Davis E, Latif SA. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:849-50. PubMed
- Quinkler M, Stewart PM. Hypertension and the cortisol-cortisone shuttle. J Clin Endocrinol Metab 2003;88:2384-92. PubMed
- Westman EC, Guthrie GP. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:850. PubMed
- Mu Y, Zhang J, Zhang S, et al. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. J Pharmacol Exp Ther 2006;316:1369-77. PubMed
- Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Intern Med 2007;46:575-8. PubMed
- Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Am J Psychiatry 1994;151:617-8. PubMed
- de Klerk GJ, Nieuwenhuis G, Beutler JJ. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ 1997;314:731-2.
- Dellow EL, Unwin RJ, Honour JW. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. Nephol Dial Transplant 1999;14:218-20. PubMed
- Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc 2003;78:767-8. PubMed
- Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. J Intern Med 1999;245:307-10.
- Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. Neth J Med 2005;63:149-50.
- Lin SH, Yang SS, Chau T, Halperin ML. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Am J Med Sci 2003;325:153-6. PubMed
- van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. Neth J Med 2005;63:146-8.
- van Uum SH. Liquorice and hypertension. Neth J Med 2005;63:119-20.
- Russo S, Mastropasqua M, Mosetti MA, et al. Low doses of liquorice can induce hypertension encephalopathy. Am J Nephrol 2000;20:145-8. PubMed
- Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. Food Chem Toxicol 1993;31:303-12. PubMed
- Sontia B, Mooney J, Gaudet L, Touyz RM. Pseudohyperaldosteronism, liquorice, and hypertension. J Clin Hypertens (Greenwich) 2008;10:153-7. PubMed
- Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. Phytother Res 2008;22:563-5. PubMed
- Lapi F, Gallo E, Bernasconi S, et al. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Br J Clin Pharmacol 2008;66:572-4. PubMed
- Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Endocrinol Jpn 1990;37:331-41. PubMed
- Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Lancet 1990;335(8697):1060-3. PubMed
- Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Klin Wochenschr 1983;61:303-5. PubMed
- Hukkanen J, Ukkola O, Savolainen MJ. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Blood Press 2009;18:192-5. PubMed
- Bisogni V, Rossi GP, Calò LA. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. Blood Press. 2014 Jun;23(3):189-92. PubMed
- Dehours E, Vallé B, Rougé-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. J Telemed Telecare. 2013 Jun;19(4):227-8. PubMed
- Kormann R, Languille E, Amiot HM, Hertig A. Dying for a cup of tea. BMJ Case Rep. 2012 Oct 19;2012. PubMed
- Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Ann Noninvasive Electrocardiol. 2013 Nov;18(6):593-6. PubMed
- Räikkönen K, Seckl JR, Heinonen K, Pyhälä R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Järvenpää AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis fu
- Robles BJ, Sandoval AR, Dardon JD, Blas CA. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). BMJ Case Rep. 2013 Sep 19;2013. PubMed
- Chamberlain, J. J. and Abolnik, I. Z. Pulmonary edema following a licorice binge. West J Med 1997;167(3):184-185.
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