Complete CBDA + CBD Oil 25 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Complete CBDA + CBD Oil 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Complete CBDA + CBD Oil 25 mg is a dietary supplement by Bluebird Botanicals with 4 active ingredients. Its ingredients are commonly taken for skin and hair care, source of dietary fats (mcts), hydration with coconut water.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad-Spectrum Hemp, Distillate, Coconut Oil, Fractionated. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains 4 ingredients: a proprietary blend (whose specific components are listed separately), fractionated coconut oil, broad-spectrum hemp distillate, steam-distilled terpenes, and full-spectrum hemp aerial parts extract. The two hemp components—the distillate and the raw decarboxylated extract—are the active ingredients delivering the CBDA and CBD.
Fractionated coconut oil serves as a carrier and base.
Does it work?
Couldn't assess
The evidence on the hemp ingredients for any health condition isn't established in our data. The facts we hold show insufficient reliable evidence to rate hemp for constipation, eczema, or familial high cholesterol.
Similarly, coconut oil's effectiveness for diabetes, high cholesterol, obesity, or lichen planus isn't established. If you're considering this product for a specific reason, that's a conversation worth having with your doctor or pharmacist.
How safe is it?
Well-documented data
Hemp products are generally well tolerated in food amounts, though concentrated extracts and supplements are less studied. Serious side effects are rare but have been reported, including anaphylaxis, allergic reactions (hives, swelling, shortness of breath), and in one case involving very high doses in a child, elevated liver enzymes and hepatitis.
Allergies to hemp seed, while uncommon, can occur. Coconut is generally safe in normal food amounts but high-dose supplements aren't well studied; allergic reactions to coconut—ranging from hives to anaphylaxis—are possible and more common than you might expect.
The safety data we hold doesn't specify whether these ingredients are safe in pregnancy or while breastfeeding; talk with your doctor or pharmacist for personalized advice on that.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before taking this product if you use estrogen therapy or hormone replacement (Moderate interaction with hemp), blood pressure medications or ACE inhibitors, blood thinners or antiplatelet drugs, or any medication processed by your liver via CYP1A2 or CYP3A4 enzymes. Also double-check if you take diabetes medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a hemp-based CBD and CBDA product that works as a carrier oil with coconut oil. It's most important to check your medications against the search tool on this page, especially if you take estrogen therapy, blood pressure drugs, blood thinners, or medications your liver processes via the CYP1A2 or CYP3A4 pathways.
If you have a tree nut or coconut allergy, flag that before using. Talk it over with your doctor or pharmacist before starting, particularly if you take any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Complete CBDA + CBD Oil 25 mg, straight from the product label.
| Brand | Bluebird Botanicals |
|---|---|
| Barcode (UPC) | 856888005534 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 310069 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 470 mg | -- |
| Coconut Oil, Fractionated | 0 NP | -- |
| Broad-Spectrum Hemp, Distillate | 0 NP | -- |
| Terpenes, Steam-Distilled | 0 NP | -- |
| Full-Spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
CBDA: 12.5 mg per serving CBD: 12.5 mg per serving CBDA: 1500 mg per bottle CBD: 1500 mg per bottle
Non-synthetic cannabinoids derived from USA-grown hemp.
Total THC less than or equal to 114 mg per container Total THC less than or equal to 0.95 mg per serving
FDA Statement of Identity
Hemp Supplement
FDA Disclaimer Statement
This product has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA has not evaluated or approved this product for safety or efficacy.
Precautions
Do not exceed 1 mL (2 servings) per day.
Warning: Do not use if pregnant, nursing, or under 18 years of age. Consult your healthcare provider if you are using any prescription medications or have a medical condition.
Warning: Do not use if pregnant, nursing, or under 18 years of age.
This product contains hemp with <= 0.3% Delta-9-THC on a dry-weight basis. Consumption could result in a failed drug test.
Warning: Consuming this product can expose you to chemicals including Delta-9-THC, which is known to the State of California to cause birth defects or other reproductive harm. See: www.P65Warnings.ca.gov/food.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 serving (15 drops) by mouth, up to twice per day, or as directed by a medical professional.
General Statements
Scan for details
Storage
Store in a cool, dark place.
Seals/Symbols
US Hemp Authority Certified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Coconut Oil, Fractionated
- › Broad-Spectrum Hemp, Distillate
- › Terpenes, Steam-Distilled
- › Full-Spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals Drug Interactions
HelloPharmacist Interaction Report
Bluebird Botanicals' Complete CBDA + CBD Oil 25 mg has documented interactions through its fractionated coconut oil and hemp content (both the broad-spectrum distillate and full-spectrum extract).
The most serious interaction is Moderate: hemp may interfere with estrogen therapy (hormone therapy) by altering how your body handles estrogen.
Read the full breakdown — every affected drug type, severity by severity
Hemp also has Minor interactions with blood pressure medications (antihypertensive drugs and ACE inhibitors), where it may add to the blood-pressure-lowering effect and raise the risk of low blood pressure (hypotension). It may theoretically increase bleeding risk with blood thinners and antiplatelet drugs, though human evidence is limited.
Hemp may also affect how your liver breaks down certain medications that rely on the CYP1A2 and CYP3A4 enzyme systems, potentially making those drugs less effective.
Coconut oil carries a Minor interaction with diabetes medications—theoretically it could increase the risk of low blood sugar (hypoglycemia)—though this is based on animal research. We could not check terpenes; no data is on file for that ingredient.
Altogether, these interactions span 1,019 individual medications.
Use the search tool below to look up your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Complete CBDA + CBD Oil 25 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Complete CBDA + CBD Oil 25 mg interact with 1,018 drugs. Click any drug to see the details.
2 of the 4 ingredients in Complete CBDA + CBD Oil 25 mg interact with drugs. Each result below shows which ingredient is responsible. Broad-Spectrum Hemp, Distillate Coconut Oil, Fractionated
Etonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Etonogestrel, Ethinyl Estradiol interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Levonorgestrel, Ethinyl Estradiol interactionMedroxyprogesterone Acetate, Oestrogens, ConjugatedPremique
How Medroxyprogesterone Acetate, Oestrogens, Conjugated interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Medroxyprogesterone Acetate, Oestrogens, Conjugated interactionNorelgestromin, Ethinyl EstradiolEvra, Ortho Evra
How Norelgestromin, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Norelgestromin, Ethinyl Estradiol interactionNorethindrone Acetate, Ethinyl Estradiol, Ferrous FumarateLoMinastrin FE, Minastrin 24 FE
How Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interactionOestrogenOestrogen
How Oestrogen interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Oestrogen interactionPrasterone (prescription Drug)Intrarosa
How Prasterone (prescription Drug) interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Prasterone (prescription Drug) interactionRelugolix, Estradiol, Norethindrone AcetateMyfembree
How Relugolix, Estradiol, Norethindrone Acetate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Relugolix, Estradiol, Norethindrone Acetate interactionSegesterone Acetate, Ethinyl EstradiolAnnovera
How Segesterone Acetate, Ethinyl Estradiol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Segesterone Acetate, Ethinyl Estradiol interactionTiboloneLivial
How Tibolone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Tibolone interactionDrospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Drospirenone, Ethinyl Estradiol, Levomefolate interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Coconut Oil, FractionatedAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Oil, Fractionated + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Complete CBDA + CBD Oil 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, RawCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full-spectrum Hemp Aerial Parts Extract, Decarboxylated, Raw + Acetaminophen, Butalbital, Codeine Phosphate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Complete CBDA + CBD Oil 25 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Broad-Spectrum Hemp, Distillate
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Coconut Oil, Fractionated
Antidiabetes Drugs
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.
Brand information
Manufacturer and brand details for Complete CBDA + CBD Oil 25 mg, from the product label.
Bluebird Botanicals
See all Bluebird Botanicals products- Name
- Bluebird Botanicals
- City
- Louisville
- State
- CO
- ZipCode
- 80027
- Phone Number
- (720) 726-5132
- Web Address
- BluebirdBotanicals.com
Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals: Common Questions
Does Complete CBDA + CBD Oil 25 mg by Bluebird Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on hormone therapy or birth control?
What's in this oil besides the CBD and CBDA?
Does this product help with anything specific?
Is this safe if I'm allergic to tree nuts?
Are there any side effects I should know about?
Is this safe to take while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Complete CBDA + CBD Oil 25 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Coconut
Interacts with 86 drugsCoconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...
Read the full Coconut monograph → Herb & supplement monographHemp
Interacts with 938 drugsHemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...
Read the full Hemp monograph →Sources & How We Checked
Complete CBDA + CBD Oil 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coconut 10 references
- Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
- Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
- Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
- Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
- Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
- Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
- 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
- Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
- Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
- Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC