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Dietary supplement

Copper Gluconate Ingredients & Drug Interactions

by BulkSupplements.com

Copper Gluconate label
See full label image
Powder Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Copper Gluconate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Copper Gluconate is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 31 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Copper Gluconate by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Copper Gluconate by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Copper Gluconate by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: copper, delivered as copper gluconate powder. Copper is an essential mineral your body needs in small amounts for healthy nerves, bones, and immune function.

The inactive ingredient listed is the copper gluconate compound itself.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Copper's overall clinical evidence instead.

Strong

Strong clinical evidence supports Copper for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Copper deficiency — rated "Likely Effective" (Natural Medicines).

Copper supplementation is likely effective for treating copper deficiency — the main reason people take it. For other uses like Alzheimer disease, the evidence currently suggests it's possibly ineffective.

For acne, chemotherapy-related anemia, and brain tumors, we don't have enough reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is safe at the amounts found in food and standard supplements, but too much copper can become toxic, so stick to recommended doses. The data we hold doesn't include pregnancy or breastfeeding safety information for this specific ingredient, so talk with your doctor or pharmacist before taking it if you're pregnant or nursing — though copper is needed during pregnancy, staying within recommended amounts is important.

Rarely, copper contact can cause skin irritation, and in one trial, a small number of children developed superficial burns from topical copper sulfate.

Side effects, ingredient by ingredient Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 31 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take penicillamine (Cuprimine, Depen) — you'll likely need to space doses 2 hours apart. Also double-check if you're on contraceptive drugs, since they can raise your copper level.

Use the medication checker below with your exact drugs to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Copper Gluconate is appropriate if you have a documented copper deficiency or want to ensure adequate intake of this essential mineral. If you take penicillamine or birth control pills, check with us or your pharmacist first — a simple timing shift may be all you need.

Stick to recommended doses and talk to your pharmacist if you're pregnant, nursing, or have diabetes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Copper Gluconate, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) 849720002082
Net contents 250 Gram(s); 8.8 Ounce(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 253674
Product type Mineral
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Copper Gluconate by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
14 mg
Maximum serving Sizes:
14 mg
Servings per container
17857
UPC/BARCODE
849720002082
IngredientAmount% DV
Copper2 mg100%

Other ingredients: pure Copper Gluconate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested Use: Copper is potentially toxic when taken in excess. An analytical milligram scale is required to measure this supplement. Do not exceed 4 milligrams of elemental copper per day.

Formulation

Free Of: Sugar, soy, dairy, yeast, gluten, additives

Storage

Store in a dry, cool, dark place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Copper Gluconate by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Copper Gluconate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Copper Gluconate by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size14 mg Dosage formPowder Servings per container17857 Amounts shown are per serving.

Copper

Interacts with
31 drugs
2 mg per serving Form: Copper Gluconate

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Other (inactive) ingredients: Pure Copper Gluconate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Copper Gluconate by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Copper Gluconate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
31Drugs
1 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Individual Drug Interactions

The ingredients in Copper Gluconate interact with 31 drugs. Click any drug to see the details.

1 of the 1 ingredient in Copper Gluconate interact with drugs. Each result below shows which ingredient is responsible. Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Copper Gluconate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Copper Gluconate, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
bulksupplements.com
Pharmacist Counseling Corner

Copper Gluconate by BulkSupplements.com: Common Questions

Does Copper Gluconate by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Copper Gluconate has a known interaction with 31 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Copper Gluconate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is copper gluconate for?
Copper gluconate is a form of copper supplement, an essential mineral your body needs for nerve, bone, and immune health. It's most proven for treating copper deficiency. If you're not deficient, the benefit of supplementing isn't well established.
Will this help with Alzheimer's disease?
No — the evidence currently suggests copper is possibly ineffective for Alzheimer disease. If you're interested in it for that reason, talk with your doctor about approaches with stronger evidence.
Is copper safe to take every day?
Copper is safe at standard supplement doses, but excess copper can be toxic, so don't exceed recommended amounts. Stick to the label dose and avoid high-dose supplements without medical guidance.
Can I take this if I'm pregnant?
Copper is needed during pregnancy, but we don't have specific safety data on file for this ingredient in pregnancy. Talk with your doctor or pharmacist before starting — they can advise you on whether to supplement and what amount is right for you.
Does copper cause any side effects?
Most people tolerate it well. Copper contact can rarely cause skin irritation. Also, some studies show people with diabetes tend to have higher copper levels than others, though we don't yet know if extra copper worsens diabetes — another reason to check with your pharmacist if that applies to you.
Will birth control change how this works?
Oral contraceptives can raise your copper level, sometimes into the high range. It's usually not a problem, but your pharmacist should know you're on both so they can monitor if needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Copper Gluconate is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Copper Gluconate label
Go deeper

The Full Monographs Behind Copper Gluconate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

Copper Gluconate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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