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Dietary supplement

CoQ-10 100 mg Delicious Orange Flavor Ingredients & Drug Interactions

by TriSorb

CoQ-10 100 mg Delicious Orange Flavor label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CoQ-10 100 mg Delicious Orange Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CoQ-10 100 mg Delicious Orange Flavor is a dietary supplement by TriSorb with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CoQ-10 100 mg Delicious Orange Flavor by TriSorb

Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ-10 100 mg Delicious Orange Flavor by TriSorb — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of CoQ-10 100 mg Delicious Orange Flavor by TriSorb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Coenzyme Q-10, 100 mg per tablet. CoQ-10 is a natural compound your body makes and stores in cells, where it helps generate energy and acts as an antioxidant.

The rest of the tablet is made up of inactive ingredients — dextrose, microcrystalline cellulose, and several binders and flow agents (croscarmellose sodium, crospovidone, stearic acid, magnesium stearate, silicon dioxide), plus sucralose and flavoring to give it the orange taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Coenzyme Q10's overall clinical evidence instead.

Strong

Strong clinical evidence supports Coenzyme Q10 for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coenzyme Q10 deficiency — rated "Likely Effective" (Natural Medicines).
  • On file: Migraine headache — rated "Possibly Effective" (Natural Medicines).
  • On file: Congestive heart failure (CHF) — rated "Possibly Effective" (Natural Medicines).
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Natural Medicines).
  • On file: Fibromyalgia — rated "Possibly Effective" (Natural Medicines).

CoQ-10 is rated likely effective for replacing coenzyme Q-10 deficiency itself. For other uses, the evidence is less certain: it's possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy, based on the clinical research we have on file.

That means there's promise in some studies, but we don't have enough solid evidence to call it proven for these conditions.

The evidence, ingredient by ingredient Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coenzyme Q-10 is generally well tolerated when taken as directed. In clinical trials, no serious side effects were reported.

Mild gastrointestinal upset — nausea, diarrhea, heartburn, or loss of appetite — occurs in less than 1% of people, and dividing daily doses above 100 mg can help minimize this. Headache, dizziness, and insomnia have also been reported occasionally, and skin itching or rash is rare.

There isn't enough safety data for pregnancy, so it's best avoided in pregnancy unless your doctor advises otherwise. Safety data while breastfeeding is limited, so check with your doctor before using it.

Side effects, ingredient by ingredient Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this CoQ-10, double-check with your pharmacist if you take chemotherapy drugs like alkylating agents (serious concern), warfarin or other blood thinners, or medications to lower blood pressure. Altogether, these interactions span 198 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

CoQ-10 is a good choice if you have low CoQ-10 levels or want to try it for heart health or migraines — it's generally well tolerated. If you take warfarin, chemotherapy, or blood pressure medications, have a pharmacist check your specific drugs first.

Talk to your doctor if you're pregnant, breastfeeding, or being treated for cancer.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CoQ-10 100 mg Delicious Orange Flavor, straight from the product label.

Brand TriSorb
Barcode (UPC) 746888785041
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Mar 25, 2014
DSLD ID 31494
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CoQ-10 100 mg Delicious Orange Flavor by TriSorb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
746888785041
IngredientAmount% DV
Coenzyme Q-10100 mg--

Other ingredients: Dextrose, Microcrystalline Cellulose, Croscarmellose Sodium, Crospovidone, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Sucralose, Natural & Artificial Flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) fast dissolve tablets daily, preferably with a meal. For best results, allow each tablet to dissolve in mouth before swallowing

Formulation

NO: Milk, Eggs, Wheat, Gluten, Fish, Shell Fish, Nuts, Tree Nuts.

Precautions

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Seals/Symbols

HNS

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

With our advanced TriSorb(TM) Nutrient Absorption System, there are no more common absorption problems or partially dissolved capsules and tablets that your body can’t use.

Try our Entire Line of TriSorb(TM) Fast Dissolves and Enjoy Good Health! ~ TriSorb(TM) Vitamin B-12 10,000 mcg Fast Dissolves ~ TriSorb(TM) Vitamin D 2000 IU Fast Dissolves ~ TriSorb(TM) CoQ-10 100 mg Fast Dissolves ~ TriSorb(TM) Biotin 10,000 mcg Fast Dissolves ~ TriSorb(TM) Melatonin 10 mg Fast Dissolves

TriSorb(TM) CoQ-10 Fast Dissolves provide antioxidant protection and cardiovascular support in a great tasting orange flavored tablet with TriSorb(TM) technology to help promote fast absorption.

TriSorb(TM) takes daily supplements to a whole new level with our new Fast Dissolves.

TriSorb(TM) Fast Dissolves have been formulated to smoothly melt in your mouth with great tasting flavors and no unpleasant aftertaste. TriSorb(TM) Fast Dissolves are an ideal solution for seniors, and those who have trouble swallowing.

General Statements

A full 100% of your dietary supplement goes to work instantly for you. Some regular tablets and caplets can take over 20 minutes to breakdown in the stomach.

NUTRIENT ABSORPTION SYSTEM

Promotes Heart Health

FAST DISSOLVES 10X Faster Than Regular Tablets MELTS IN YOUR MOUTH

Simply place a fast dissolve tablet on your tongue and feel the tablet disintegrating rapidly, usually in a matter of seconds.

NO WATER NEEDED

As you age, your body’s levels of CoQ-10 naturally decline, sometimes as early as your 20s. Other factors may affect your CoQ-10 levels too, such as inadequate dietary intake of CoQ-10, the use of statin drugs, oxidative stress on your cells, potential effects from illness, and an increased demand from your metabolism.

DISSOLUTION COMPARISON TABLE MINUTES REGULAR TABLETS SOFT GEL TRISORB(TM) FAST DISSOLVES

Plus, they’re perfect for active, busy adults who are traveling and since you don’t need water you can take them with you wherever you go.

CoEnzyme Q-10 (CoQ-10) is found in every cell of your body. Your body makes CoQ-10 and your cells use it to produce energy your body needs for cell growth and maintenance. Additionally, it helps to maintain normal circulation, to support your immune system and to help protect cells from aging.* CoQ-10 helps enzymes work to digest food and perform other body processes, and they help protect the heart and skeletal muscles.

FDA Statement of Identity

DIETARY SUPPLEMENT

Storage

Store at room temperature.

General

B-85041

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CoQ-10 100 mg Delicious Orange Flavor by TriSorb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CoQ-10 100 mg Delicious Orange Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CoQ-10 100 mg Delicious Orange Flavor by TriSorb

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Coenzyme Q-10

Interacts with
198 drugs
100 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Other (inactive) ingredients: Dextrose, Microcrystalline Cellulose, Croscarmellose Sodium, Crospovidone, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Sucralose, Natural & Artificial Flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

CoQ-10 100 mg Delicious Orange Flavor by TriSorb Drug Interactions

Want to check YOUR meds against CoQ-10 100 mg Delicious Orange Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
26 Moderate 172 Minor

Ingredients driving the most interactions

Coenzyme Q-10 198

Individual Drug Interactions

The ingredients in CoQ-10 100 mg Delicious Orange Flavor interact with 198 drugs. Click any drug to see the details.

1 of the 1 ingredient in CoQ-10 100 mg Delicious Orange Flavor interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10

Each ingredient & the kinds of drugs it affects

For each ingredient in CoQ-10 100 mg Delicious Orange Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q-10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CoQ-10 100 mg Delicious Orange Flavor, from the product label.

TriSorb

See all TriSorb products
Name
HEALTHY NATURAL SYSTEMS(R)
Street Address
3750 Investment Lane, Suite 2
City
West Palm Beach
State
FL
ZipCode
33404
Web Address
www.TriSorb.com
Pharmacist Counseling Corner

CoQ-10 100 mg Delicious Orange Flavor by TriSorb: Common Questions

Does CoQ-10 100 mg Delicious Orange Flavor by TriSorb interact with any medications?
Yes. Based on its ingredients, CoQ-10 100 mg Delicious Orange Flavor has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CoQ-10 100 mg Delicious Orange Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Coenzyme Q-10 actually used for in my body?
CoQ-10 is a natural compound that helps your cells make energy and protects them from damage. Your body makes some on its own, but levels can drop with age or certain medications.
Can I take this if I'm on warfarin?
You can, but you'll need to be careful. CoQ-10 may reduce warfarin's blood-thinning effect, so your doctor or pharmacist should monitor your INR (clotting measure) to make sure the warfarin is still working properly.
Does CoQ-10 actually work for heart health?
The evidence shows it's possibly effective for congestive heart failure, meaning some research is promising but we don't have enough solid proof yet. Talk to your doctor about whether it's a good fit for your specific situation.
Is it safe to take during pregnancy?
There isn't enough reliable safety data for pregnancy, so it's best to avoid it unless your doctor advises otherwise. Check with your doctor for personalized guidance.
What side effects should I watch for?
Most people tolerate it well. Mild stomach upset, heartburn, or nausea happens in less than 1% of users — dividing your dose can help. Headache, dizziness, or trouble sleeping have been reported rarely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CoQ-10 100 mg Delicious Orange Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CoQ-10 100 mg Delicious Orange Flavor label
Go deeper

The Full Monographs Behind CoQ-10 100 mg Delicious Orange Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

CoQ-10 100 mg Delicious Orange Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
  37. Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
  39. Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
  40. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed

See these in context on the Coenzyme Q10 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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