Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

CoQ10 60 mg With 200 mg Lecithin Ingredients & Drug Interactions

by NOW

CoQ10 60 mg With 200 mg Lecithin label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CoQ10 60 mg With 200 mg Lecithin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CoQ10 60 mg With 200 mg Lecithin is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CoQ10 60 mg With 200 mg Lecithin by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 60 mg With 200 mg Lecithin by NOW — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of CoQ10 60 mg With 200 mg Lecithin by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: coenzyme Q10 (60 mg) and lecithin (200 mg). CoQ10 is a natural substance your body makes and stores in your cells; it's involved in energy production and has antioxidant properties.

Lecithin is a fatty substance found in foods like eggs and soybeans; it's used in supplements for various health purposes. The product also contains inactive ingredients — rice flour, gelatin, and magnesium stearate — which are fillers and binders that hold the capsule together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: CoQ10 supports healthy cardiovascular and immune function.
  • We looked for evidence on: Cardiovascular disease (CVD), Congestive heart failure (CHF), Myocardial infarction (MI), Angina, Hypertension, Hyperlipidemia — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Likely Effective" for Coenzyme Q10 deficiency (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF), Myocardial infarction (MI).
  • Also on file: Coenzyme Q10 is rated "Insufficient Reliable Evidence To Rate" for Angina, Cardiovascular disease (CVD), Hyperlipidemia, Hypertension.

CoQ10 is likely effective for CoQ10 deficiency itself. It's possibly effective for fibromyalgia, migraine headaches, congestive heart failure (CHF), and diabetic neuropathy, though the evidence isn't conclusive.

Lecithin has been studied for Alzheimer's disease but is likely ineffective for that use. For age-related cognitive decline, anxiety, and bipolar disorder, the evidence on lecithin is too limited to rate.

Neither ingredient has strong proof for most of the conditions they're marketed for, so talk with your doctor about whether this product makes sense for your situation.

The evidence, ingredient by ingredient Lecithin Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

CoQ10 is generally well tolerated. The most common side effects are gastrointestinal — appetite suppression, diarrhea, heartburn, nausea, and vomiting — and these occur in less than 1% of people.

Headache, dizziness, and insomnia have been reported rarely. If you take doses over 100 mg, splitting them throughout the day can help minimize stomach upset.

Lecithin is generally considered safe in food and supplement amounts, though it can cause abdominal pain, diarrhea, fullness, and nausea in some people. If you have an egg or soy allergy, lecithin may trigger allergic skin reactions.

Both ingredients are likely safe in pregnancy. Breastfeeding safety data for CoQ10 is limited — check with your doctor before using.

Lecithin is often used to help with clogged milk ducts, but confirm with your healthcare provider first.

Side effects, ingredient by ingredient Lecithin Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take warfarin or other blood thinners — CoQ10 may reduce their effectiveness. Also double-check if you're on chemotherapy (especially alkylating agents like cyclophosphamide) or blood pressure medications, where CoQ10 could interfere with how they work or cause your blood pressure to drop too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you have CoQ10 deficiency or want to try it for migraine, heart failure, or fibromyalgia — though the evidence is mixed. If you take warfarin, any chemotherapy, or blood pressure medications, you must check with your pharmacist before starting.

CoQ10 can interfere with how these drugs work. Generally, it's mild on your stomach, but gastrointestinal side effects are possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CoQ10 60 mg With 200 mg Lecithin, straight from the product label.

Brand NOW
Net contents 155 Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 13088
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CoQ10 60 mg With 200 mg Lecithin by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Lecithin200 mg--
Coenzyme Q1060 mg--

Other ingredients: Rice Flour, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Good Manufacturing Practices GMP NNfA

35th Anniversary

FDA Statement of Identity

A Dietary Supplement

Formulation

Contains no yeast, wheat, gluten, corn, milk, egg or additives.

General Statements

Bonus 35 Free

Coenzyme Q10 is a vitamin-like compound also called ubiquinone. It is an essential component of cells and is necessary for mitochondrial energy production. Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production. Our Coenzyme Q10 is produced exclusively in Japan through a natural fermentation process. Look for other fine NOW(R) products in health food stores nationwide.

Highest Quality

120 + 35 Free Capsules

This seal certifies that the manufacturer of this product uses quality systems and procedures that comply with NNFA’s Dietary Supplement GMP standards. The quality of individual ingredients, however, has not been certified.

Made in the U.S.A.

35th Anniversary

ACTUAL SIZE

General

CODE 9564

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 capsule 1-2 times daily, preferably with meals.

FDA Disclaimer Statement

*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

CAUTION: PLEASE DISCARD THE INEDIBLE FRESHNESS PACKET ENCLOSED.

Formula

CoQ10 60 mg with 200 mg Lecithin

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CoQ10 60 mg With 200 mg Lecithin by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CoQ10 60 mg With 200 mg Lecithin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CoQ10 60 mg With 200 mg Lecithin by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lecithin

No known
interactions
200 mg per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Lecithin monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
60 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

CoQ10 60 mg With 200 mg Lecithin by NOW Drug Interactions

Want to check YOUR meds against CoQ10 60 mg With 200 mg Lecithin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
26 Moderate 172 Minor

Ingredients driving the most interactions

Coenzyme Q10 198

Individual Drug Interactions

The ingredients in CoQ10 60 mg With 200 mg Lecithin interact with 198 drugs. Click any drug to see the details.

1 of the 2 ingredients in CoQ10 60 mg With 200 mg Lecithin interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q10

Each ingredient & the kinds of drugs it affects

For each ingredient in CoQ10 60 mg With 200 mg Lecithin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CoQ10 60 mg With 200 mg Lecithin, from the product label.

NOW

See all NOW products
Name
NOW FOODS
City
BLOOMINGDALE
State
IL
ZipCode
60108
Pharmacist Counseling Corner

CoQ10 60 mg With 200 mg Lecithin by NOW: Common Questions

Does CoQ10 60 mg With 200 mg Lecithin by NOW interact with any medications?
Yes. Based on its ingredients, CoQ10 60 mg With 200 mg Lecithin has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CoQ10 60 mg With 200 mg Lecithin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any side effects?
CoQ10 can cause gastrointestinal upset — diarrhea, nausea, heartburn, and loss of appetite — though this happens in less than 1% of people. Headache, dizziness, and insomnia have been reported rarely. Lecithin may cause abdominal pain, diarrhea, or nausea, and can trigger allergic skin reactions if you're allergic to eggs or soy. Taking CoQ10 doses above 100 mg in divided amounts throughout the day can help reduce stomach problems.
Is this safe to take while pregnant or breastfeeding?
CoQ10 is likely safe in pregnancy. For breastfeeding, safety data on CoQ10 is limited — check with your doctor first. Lecithin is likely safe in pregnancy and lactation and is often used to help with clogged milk ducts, but confirm with your healthcare provider before starting any supplement while breastfeeding.
What is CoQ10 supposed to do?
CoQ10 is a substance your body naturally produces that helps your cells make energy. It's likely effective for CoQ10 deficiency and possibly effective for migraine headaches, fibromyalgia, congestive heart failure, and diabetic neuropathy — though the evidence isn't conclusive for these uses. Some research suggests it can lower blood pressure, though results vary.
What does lecithin do?
Lecithin is a fatty substance used in supplements for various purposes, including supporting brain and nerve function. It's been studied for Alzheimer's disease but is likely ineffective for that condition. The evidence for its use in age-related cognitive decline, anxiety, and bipolar disorder is too limited to say whether it works.
Can I take this if I'm on blood pressure medication?
CoQ10 may lower blood pressure on its own, so combining it with blood pressure drugs could cause your blood pressure to drop too much. Talk to your pharmacist or doctor before starting this product if you're on any blood pressure medication.
What if I'm taking warfarin?
Do not start this product without checking with your pharmacist first. CoQ10 is chemically similar to vitamin K and may reduce how well warfarin works — four cases of decreased warfarin effectiveness linked to CoQ10 have been reported. Your doctor or pharmacist needs to monitor you closely if you decide to use both.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CoQ10 60 mg With 200 mg Lecithin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CoQ10 60 mg With 200 mg Lecithin label
Go deeper

The Full Monographs Behind CoQ10 60 mg With 200 mg Lecithin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lecithin

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...

Read the full Lecithin monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

CoQ10 60 mg With 200 mg Lecithin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 49 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
  37. Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
  39. Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
  40. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed

See these in context on the Coenzyme Q10 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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