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Dietary supplement

Corn Silk Ingredients & Drug Interactions

by Herb Pharm

Corn Silk label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Corn Silk against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Corn Silk is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 290 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Corn Silk. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Corn Silk by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Corn Silk by Herb Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Corn Silk by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: corn silk (the fine threads you find inside an ear of corn). It comes as a liquid extract made with certified organic grain alcohol.

The extractives preserve corn silk's compounds in a form your body can absorb quickly.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Urinary tract and kidney health support.
  • We looked for evidence on: Nocturnal enuresis, Prostatitis, Urinary tract infections (UTIs), Kidney stones (nephrolithiasis), Bladder health, Mild fluid retention — and 1 related terms.
  • The closest evidence on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis) (Natural Medicines).
  • Also on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Prostatitis, Urinary tract infections (UTIs), Nocturnal enuresis.

The evidence we hold doesn't establish that corn silk works for the conditions listed — angina, heart disease, heart failure, depression, diabetes, or fatigue all carry a rating of insufficient reliable evidence. That doesn't mean it doesn't help; it means rigorous research in humans hasn't been done yet for these uses.

The evidence, ingredient by ingredient Corn Silk

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Corn silk is generally well tolerated for short-term use, but human safety data are limited, so we don't know as much as we'd like. The most common side effects when taken by mouth are low potassium (hypokalemia) and low sodium (hyponatremia), especially with long-term use.

We don't have enough reliable safety data to recommend it during pregnancy, so it's best avoided then. Safety while breastfeeding is unknown — talk with your doctor or pharmacist before use if you're nursing.

Side effects, ingredient by ingredient Corn Silk

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Corn Silk.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 290 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check blood pressure medications, diabetes drugs, water pills (diuretics), corticosteroids, and warfarin or other blood thinners with your pharmacist or using the tool on this page — all carry Moderate risk interactions with corn silk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Corn silk may be worth considering if you're interested in traditional herbal support, but it's not a casual add-on if you take blood pressure, diabetes, water-pill, corticosteroid, or blood-thinner medications. Check your exact prescriptions with our tool first, and have a conversation with your pharmacist about whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Corn Silk, straight from the product label.

Brand Herb Pharm
Net contents 8 fl. Oz.
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 23370
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Corn Silk by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
40 Drop(s)
IngredientAmount% DV
Corn Silk0 NP--

Other ingredients: certified organic Grain Alcohol, Corn Silk extractives

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep Out of the Reach of Children

General Statements

We prepare our Corn Silk Extract from the fresh stigma & style ('silk') of corn ears (Zea mays) which are Certified Organically Grown without the use of chemical fertilizers, pesticides, or herbicides. To assure optimal extraction of Corn Silk's bioactive compounds, the silk is carefully hand-harvested and is then taken directly to our laboratory and promptly extracted while still fresh and succulent. Our Corn Silk is never fumigated or irradiated.

400027-2W12

LIQUID HERBAL EXTRACT

Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before Using Two to five times per day take 30 to 40 drops in a little water.

Shake Well Before Dispensing From This Bottle

General

003

FDA Statement of Identity

HERBAL DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Corn Silk by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Corn Silk label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Corn Silk by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.

Corn Silk

Interacts with
290 drugs
0 NP per serving

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence...

Corn Silk monograph & interactions

Other (inactive) ingredients: Certified organic Grain Alcohol, Corn Silk extractives. These complete the product’s ingredient list but are not active constituents.

Interaction report

Corn Silk by Herb Pharm Drug Interactions

Want to check YOUR meds against Corn Silk?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
290Drugs
290 Moderate

Ingredients driving the most interactions

Corn Silk 290

Individual Drug Interactions

The ingredients in Corn Silk interact with 290 drugs. Click any drug to see the details.

1 of the 1 ingredient in Corn Silk interact with drugs. Each result below shows which ingredient is responsible. Corn Silk

Each ingredient & the kinds of drugs it affects

For each ingredient in Corn Silk with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Corn Silk5 drug types · 290 drugs

Antidiabetes Drugs

Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.

Likelihood Possible Evidence D
Corticosteroids

Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.

Likelihood Possible Evidence D
Diuretic Drugs

Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.

Likelihood Likely Evidence D
Corn Silk full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Corn Silk, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Corn Silk by Herb Pharm: Common Questions

Does Corn Silk by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Corn Silk has a known interaction with 290 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Corn Silk contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is corn silk, exactly?
Corn silk is the fine, hair-like threads you find inside the husk of corn. In this product, it's extracted and preserved in alcohol so you can take it as a supplement.
Can I take corn silk if I'm pregnant or breastfeeding?
No — there isn't enough reliable safety data during pregnancy, so it's best avoided. If you're breastfeeding, safety is unknown, so talk with your doctor or pharmacist before you use it.
What are the most common side effects?
The main ones reported are low potassium and low sodium in your blood, especially if you take it long-term. Otherwise, adverse effects seem to be rare, though a thorough safety study hasn't been done.
Does corn silk actually work for blood sugar or blood pressure?
Animal research and some studies in people suggest it may lower blood sugar and blood pressure, but we don't have enough reliable human evidence yet to say it's an established treatment for diabetes or high blood pressure.
Why do I need to be consistent with this if I take warfarin?
Corn silk contains vitamin K, which affects how warfarin works. If you suddenly start, stop, or change how much you take, it can throw off your blood-thinning balance — so talk to your pharmacist about keeping your intake steady.
Is this product just corn silk, or are there other ingredients?
The active ingredient is corn silk. It's extracted using certified organic grain alcohol, which helps preserve and deliver the corn silk compounds; alcohol is also listed as an inactive ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Corn Silk is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Corn Silk label
Go deeper

The Full Monographs Behind Corn Silk’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Corn Silk

Interacts with 290 drugs

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...

Read the full Corn Silk monograph →
Sources

Sources & How We Checked

Corn Silk's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Corn Silk 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

See these in context on the Corn Silk monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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