Curamin Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Curamin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Curamin is a dietary supplement by Terry Naturally with 5 active ingredients. Its ingredients are commonly taken for heart and circulatory health, blood clot prevention, high blood pressure.Based on those ingredients, 1,126 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BOS-10, Nattokinase. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Curamin by Terry Naturally
Ask about any prescription or over-the-counter medication and we check it for interactions with Curamin by Terry Naturally — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Curamin by Terry Naturally
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Curamin contains 4 active ingredients. Nattokinase is an enzyme derived from fermented soybeans with blood-thinning properties.
DL-Phenylalanine is an amino acid form used in supplements. BOS-10 is a standardized extract of Boswellia serrata (frankincense resin), traditionally used for inflammation.
BCM-95 Curcugreen is a curcumin formulation, the active compound in turmeric. The capsules also contain inactive ingredients: hydroxypropyl methylcellulose (a plant-based capsule material), magnesium stearate (a flow agent), and silica (an anti-caking agent).
Does it work?
Moderate evidence
For Boswellia serrata, evidence shows it is possibly effective for osteoarthritis. The data we hold does not establish effectiveness for allergic rhinitis, Alzheimer disease, asthma, or cluster headache.
For the other ingredients — nattokinase, DL-Phenylalanine, and BCM-95 Curcugreen — the effectiveness ratings in our data cover conditions like angina, atherosclerosis, cardiovascular disease, and cancer, but all carry a rating of insufficient reliable evidence. We cannot answer what Curamin as a complete product is intended to treat based on the facts provided.
How safe is it?
Well-documented data
Nattokinase is generally well tolerated short-term but carries a caution because of its blood-thinning effect — people with bleeding disorders or at high bleeding risk should be cautious. It has caused rare reports of hemorrhage, including one case of brain bleeding when combined with aspirin.
Hypersensitivity reactions, including anaphylaxis, can occur in people sensitive to natto soybeans. Safety data is insufficient during pregnancy and breastfeeding, so both are best avoided.
Boswellia serrata is generally well tolerated short-term, though quality and dose vary widely between products. Common side effects include abdominal pain, diarrhea, headache, heartburn, nausea, and dizziness.
Rarely, large amounts can form a blockage in the stomach. Safety is insufficient during pregnancy and breastfeeding, so both are best avoided.
Meds to double-check
Moderate interaction found
Before taking Curamin, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (like aspirin, warfarin, or clopidogrel) — nattokinase increases bleeding risk. If you take blood pressure medications, nattokinase may lower your pressure further.
Additionally, check any medications your liver breaks down, especially antidepressants, heart drugs, and statins — Boswellia may increase their blood levels. Also check any immunosuppressants used after transplant or for autoimmune conditions.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Curamin may be considered by people looking for anti-inflammatory support, though evidence for specific uses is limited. If you take blood thinners, blood pressure medications, or drugs your liver processes, you need to check with your doctor or pharmacist before starting — the interactions are real and potentially serious.
Anyone with a history of bleeding, natto allergy, or who is pregnant or breastfeeding should talk with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Curamin, straight from the product label.
| Brand | Terry Naturally |
|---|---|
| Barcode (UPC) | 367703102203 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 304502 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Curamin by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Total Fat | 0.5 Gram(s) | 1% |
| Protein | 1 Gram(s) | 1% |
| Nattokinase | 0 NP | -- |
| DL-Phenylalanine | 0 NP | -- |
| BOS-10 | 0 NP | -- |
| Proprietary Complex | 2181 mg | -- |
| BCM-95 Curcugreen | 0 NP | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Money-back guarantee
Visit Curamin.com to read what others have experienced.
For Your Good Health Terry
Color variations are normal.
Formula
Four powerhouse ingredients. One award-winning formula. Curamin combines clinically proven curcumin and boswellia with DLPA and nattokinase to create a product that has been recognized throughout the natural foods industry for pain relief. When pain is the problem, Curamin is the answer!
Clinically studied Curcumin with Turmerones
H Halal
CRC Kosher
Suggested/Recommended/Usage/Directions
Recommendations: Take three capsules daily. May take as one capsule three times daily.
Precautions
If pregnant or nursing, consult a healthcare practitioner before use.
Contains soy (less than 5 parts per million)
Formulation
Occasional muscle pain due to exercise or overuse
Pain relief Safe, effective, non-addictive pain relief Occasional muscle pain due to exercise or overuse
No sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.
Vegan
Non-GMO
All ingredients established in human studies for safety and effectiveness. Does not interfere with stomach, liver or kidney function.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
H Halal
CRC Kosher
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Curamin by Terry Naturally label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Curamin by Terry Naturally
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
Proprietary Complex
- › Nattokinase
- › DL-Phenylalanine
- › BOS-10
- › BCM-95 Curcugreen
Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Curamin by Terry Naturally Drug Interactions
HelloPharmacist Interaction Report
Curamin by Terry Naturally contains nattokinase and Boswellia serrata (BOS-10), both of which interact with medications.
The most serious concern is nattokinase's Moderate risk of bleeding when combined with blood thinners or antiplatelet drugs like aspirin, warfarin, or clopidogrel — there is a documented case of brain bleeding in someone who added nattokinase to low-dose aspirin. Nattokinase also carries a Moderate risk of dangerously low blood pressure if you're on blood pressure medications.
Read the full breakdown — every affected drug type, severity by severity
Boswellia serrata affects how your body breaks down many common drugs through multiple liver enzyme pathways. It can increase blood levels of medications metabolized by CYP2D6, CYP2C19, CYP1A2, CYP2C9, and CYP3A4 enzymes — a Moderate concern with each group.
This matters because these pathways handle a huge range of medications: certain antidepressants, some beta-blockers and other heart drugs, blood thinners, statins, and many others. Boswellia may also theoretically interfere with immunosuppressant medications used after transplant or for autoimmune conditions.
We could not check DL-Phenylalanine or BCM-95 Curcugreen for interactions — no data is on file for either. Altogether, these interactions span 1,127 individual medications.
Before starting Curamin, check your exact medications with your doctor or pharmacist, especially if you take any blood thinner, blood pressure medication, or drugs your liver breaks down.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Curamin?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Curamin interact with 1,126 drugs. Click any drug to see the details.
2 of the 5 ingredients in Curamin interact with drugs. Each result below shows which ingredient is responsible. BOS-10 Nattokinase
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Immunosuppressants Moderate
Interaction Summary
Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Read the full Bos-10 + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
NattokinaseAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Curamin — through 2 ingredients. Tap an ingredient for the detail:
Bos-10Immunosuppressants, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Read the full Bos-10 + Abrocitinib interactionNattokinaseAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Acalabrutinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
NattokinaseAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Nattokinase + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
NattokinaseAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Curamin — through 2 ingredients. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Aspirin interactionNattokinaseAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Curamin — through 2 ingredients. Tap an ingredient for the detail:
NattokinaseAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Nattokinase + Acetaminophen, Aspirin, Caffeine interactionBos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Bos-10 + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
Read the full Bos-10 + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Bos-10 + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Bos-10 + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Curamin — through 1 ingredient. Tap an ingredient for the detail:
Bos-10Cytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
Read the full Bos-10 + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Curamin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
BOS-10
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.
Immunosuppressants
Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.
Nattokinase
Anticoagulant/Antiplatelet Drugs
Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Nattokinase has thrombolytic and anticoagulant effects. There is a case report of intracranial hemorrhage in a patient who added nattokinase to aspirin therapy.
Antihypertensive Drugs
Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.
Some clinical research suggests that nattokinase may reduce systolic and diastolic blood pressure.
Brand information
Manufacturer and brand details for Curamin, from the product label.
Terry Naturally
See all Terry Naturally products- Name
- EuroPharma, Inc.
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- (866) 807-2731
- Web Address
- EuroPharmaUSA.com
Curamin by Terry Naturally: Common Questions
Does Curamin by Terry Naturally interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does nattokinase really thin the blood?
What is BOS-10, and what's it supposed to do?
Can I take Curamin if I'm pregnant or breastfeeding?
Are there common side effects I should know about?
What is DL-Phenylalanine?
Why does this product interact with so many medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Curamin is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Curamin’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Nattokinase
Interacts with 289 drugsNattokinase is an enzyme from the fermented soybean food natto that may have mild blood-thinning and blood-flow effects. Some small studies hint at benefits for blood pressure and circulatio...
Read the full Nattokinase monograph → Herb & supplement monographBoswellia Serrata
Interacts with 952 drugsBoswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...
Read the full Boswellia Serrata monograph →Sources & How We Checked
Curamin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Nattokinase 9 references
- Suzuki Y, Kondo K, Matsumoto Y, et al. Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci 2003;73:1289-98.. PubMed
- Sumi H, Hamada H, Nakanishi K, Hiratani H. Enchancement of fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol 1990;84:139-43.
- Chang, Y. Y., Liu, J. S., Lai, S. L., Wu, H. S., and Lan, M. Y. Cerebellar hemorrhage provoked by combined use of nattokinase and aspirin in a patient with cerebral microbleeds. Intern Med 2008;47(5):467-469. PubMed
- Kim, J. Y., Gum, S. N., Paik, J. K., Lim, H. H., Kim, K. C., Ogasawara, K., Inoue, K., Park, S., Jang, Y., and Lee, J. H. Effects of nattokinase on blood pressure: a randomized, controlled trial. Hypertens.Res 2008;31(8):1583-1588. PubMed
- <p>Maruyama M, Sumi H (eds): Effect of natto diet on blood pressure, in Basic and Clinical Aspects of Japanese Traditional Food Natto II. Japan Technology Transfer Association (JTTAS), 1998, pp 1–3.</p>
- Kurosawa Y, Nirengi S, Homma T, et al. A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles. Sci Rep 2015;5:11601. PubMed
- Ramachandran L, Aqeel A, Jafri A, Sidhu Y, Mohamed Djirdeh T. Nattokinase-associated hemoperitoneum in an elderly woman. Cureus 2021;13(12):e20074. PubMed
- Awatani-Yoshidome K, Hashimoto T, Satoh T. Anaphylaxis from nattokinase in a patient with fermented soybean (natto) allergy. Allergol Int 2022;71(1):153-4. PubMed
- Suzuki K, Nakamura M, Sato N, Futamura K, Matsunaga K, Yagami A. Nattokinase, a subtilisin family serine protease, is a novel allergen contained in the traditional Japanese fermented food natto. Allergol Int 2022.
Boswellia Serrata 16 references
- Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
- Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
- Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
- Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
- Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
- Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
- Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
- Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
- Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
- Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
- El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
- Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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