David Winston's Grief Relief Ingredients & Drug Interactions
What is this page for?
First and foremost: checking David Winston's Grief Relief against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
David Winston's Grief Relief is a dietary supplement by Herbalist & Alchemist with 3 active ingredients. Its ingredients are commonly taken for anxiety and stress, low mood or mild depression, sleep trouble (insomnia).Based on those ingredients, 420 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Mimosa bark extract, Hawthorn berry, flower & leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against David Winston's Grief Relief by Herbalist & Alchemist
Ask about any prescription or over-the-counter medication and we check it for interactions with David Winston's Grief Relief by Herbalist & Alchemist — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of David Winston's Grief Relief by Herbalist & Alchemist
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains three active ingredients. Mimosa bark extract (from Albizia julibrissin) and hawthorn berry, flower, and leaf extract are the primary herbal components; rose petal extract is also included.
The product is delivered in a base of distilled water, ethyl alcohol, and vegetable glycerin.
Does it work?
Not established
We don't have established effectiveness ratings in our data for the conditions this product is marketed for. The evidence for hawthorn itself for heart-related conditions like angina, arrhythmia, and cardiovascular disease is insufficient to rate reliably.
If you're considering this product for a specific health concern, talk with your doctor or pharmacist about whether the evidence supports its use for your situation.
How safe is it?
Well-documented data
Hawthorn is generally well tolerated when used as directed, though anyone with a heart condition needs medical supervision. Mimosa bark extract has limited human safety data, so it should be used carefully and under professional guidance.
The safety data on both ingredients during pregnancy is inadequate—the facts advise against use in pregnancy. There is not enough information to know whether either ingredient is safe while breastfeeding, so talk with your doctor or pharmacist before using this product if you're nursing.
Meds to double-check
Major interaction found
Before taking this, double-check with your doctor or pharmacist if you take: nitrates or phosphodiesterase-5 inhibitors like sildenafil (Major risk of dangerously low blood pressure), blood pressure medications including beta-blockers or calcium channel blockers, blood thinners or antiplatelet drugs like warfarin or aspirin, digoxin for the heart, or any sedatives or sleeping pills.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
This product combines hawthorn and mimosa bark, both of which can interact meaningfully with heart medications, blood pressure drugs, blood thinners, sedatives, and others. If you take any prescription medication—especially for your heart, blood pressure, or bleeding risk—check your exact list with your doctor or pharmacist before starting.
Pregnant people and those breastfeeding should discuss this product with their healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about David Winston's Grief Relief, straight from the product label.
| Brand | Herbalist & Alchemist |
|---|---|
| Barcode (UPC) | 667056134037 |
| Net contents | 2 fl. Oz.; 60 mL |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2019 |
| DSLD ID | 209084 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for David Winston's Grief Relief by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 2.25 mL | -- |
| Mimosa bark extract | 0 NP | -- |
| Rose petal extract | 0 NP | -- |
| Hawthorn berry, flower & leaf extract | 0 NP | -- |
Other ingredients: distilled Water, Ethyl Alcohol, Vegetable Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Supports emotional balance
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Suggested use: 40-45 drops (2-2.25 mL) in juice or water. Take 3 times per day. Shake well before using.
Precautions
Contraindications: Use cautiously and under the care of a qualified expert during pregnancy or when taking antidepressant medications.
Do not use if you have bipolar disorder.
Keep out of children's reach
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
OK
Formula
OK
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David Winston's Grief Relief by Herbalist & Alchemist label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in David Winston's Grief Relief by Herbalist & Alchemist
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container27 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Mimosa bark extract
- › Rose petal extract
- › Hawthorn berry, flower & leaf extract
Other (inactive) ingredients: Distilled Water, Ethyl Alcohol, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.
David Winston's Grief Relief by Herbalist & Alchemist Drug Interactions
HelloPharmacist Interaction Report
David Winston's Grief Relief by Herbalist & Alchemist contains mimosa bark extract and hawthorn berry, flower, and leaf extract—both of which interact with medications.
The most serious interactions are with nitrates and phosphodiesterase-5 inhibitors (like sildenafil for erectile dysfunction), both Major severity: hawthorn may cause additive blood-vessel relaxation and dangerously low blood pressure when combined with either.
Read the full breakdown — every affected drug type, severity by severity
Hawthorn also has Moderate interactions with blood pressure medications (beta-blockers and calcium channel blockers), blood thinners and antiplatelet drugs (aspirin, warfarin), and digoxin (a heart medication). Mimosa bark extract carries a Moderate interaction with central nervous system depressants (sedatives, sleeping pills, anesthetics), which it may enhance.
We could not check rose petal extract—we hold no interaction data for it.
Altogether, these interactions span 420 individual medications. Use the search tool below to check your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against David Winston's Grief Relief?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in David Winston's Grief Relief interact with 420 drugs. Click any drug to see the details.
2 of the 3 ingredients in David Winston's Grief Relief interact with drugs. Each result below shows which ingredient is responsible. Mimosa bark extract Hawthorn berry, flower & leaf extract
AvanafilStendra
How Avanafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry, Flower & Leaf Extract + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry, Flower & Leaf Extract + Vardenafil interactionAbciximabReoPro
How Abciximab interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry, Flower & Leaf Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry, Flower & Leaf Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn Berry, Flower & Leaf Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry, Flower & Leaf Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry, Flower & Leaf Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry, Flower & Leaf ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry, Flower & Leaf Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with David Winston's Grief Relief — through 1 ingredient. Tap an ingredient for the detail:
Mimosa Bark ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice.
Read the full Mimosa Bark Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in David Winston's Grief Relief with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Mimosa bark extract
Cns Depressants
Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice. Theoretically, Albizia julibrissin might enhance the therapeutic and adverse effects of CNS depressants.
Some CNS depressants include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), clonazepam (Klonopin), lorazepam (Ativan), zolpidem (Ambien), and others.
Hawthorn berry, flower & leaf extract
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Brand information
Manufacturer and brand details for David Winston's Grief Relief, from the product label.
Herbalist & Alchemist
See all Herbalist & Alchemist products- Name
- Herbalist & Alchemist, Inc.
- City
- Washington
- State
- NJ
- ZipCode
- 07882
- Phone Number
- 800-611-8235
- Web Address
- www.herbalist-alchemist.com
David Winston's Grief Relief by Herbalist & Alchemist: Common Questions
Does David Winston's Grief Relief by Herbalist & Alchemist interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Is this safe while breastfeeding?
Can I take this with my heart medications?
What does the hawthorn in this product actually do?
Are there any side effects I should know about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if David Winston's Grief Relief is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind David Winston's Grief Relief’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Albizia Julibrissin
Interacts with 248 drugsAlbizia julibrissin (Persian silk tree, He Huan) is a plant used in traditional Chinese medicine, mainly the flower and bark, for calming the mind, lifting mood, and easing sleep problems. H...
Read the full Albizia Julibrissin monograph → Herb & supplement monographHawthorn
Interacts with 191 drugsHawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...
Read the full Hawthorn monograph →Sources & How We Checked
David Winston's Grief Relief's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Albizia Julibrissin 1 reference
- Kang, T. H., Jeong, S. J., Kim, N. Y., Higuchi, R., and Kim, Y. C. Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz. J Ethnopharmacol 2000;71(1-2):321-323. PubMed
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
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