Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

DopaTropic Powder Ingredients & Drug Interactions

by Biotics Research Corporation

DopaTropic Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking DopaTropic Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

DopaTropic Powder is a dietary supplement by Biotics Research Corporation with 2 active ingredients. Its ingredients are commonly taken for parkinson's disease symptoms, male fertility and libido, mood and stress support.Based on those ingredients, 193 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Mucuna pruriens. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against DopaTropic Powder by Biotics Research Corporation

Ask about any prescription or over-the-counter medication and we check it for interactions with DopaTropic Powder by Biotics Research Corporation — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of DopaTropic Powder by Biotics Research Corporation

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

DopaTropic Powder contains one active ingredient: Mucuna pruriens (cowhage), a tropical plant seed that's a natural source of levodopa — the same active compound used in Parkinson's medications. The powder also includes erythritol, a sugar alcohol used as a filler.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cowhage product and its label doesn't state a use — see Cowhage's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence supporting Mucuna pruriens for any condition is insufficient in our data. Claims about its use for anxiety, skin redness (erythema), high prolactin levels (hyperprolactinemia), muscle pain (myalgia), Parkinson disease, and rheumatoid arthritis all lack reliable evidence to establish whether it works.

If you're considering this supplement for a specific condition, talk with your doctor or pharmacist about what the current science actually supports.

The evidence, ingredient by ingredient Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral side effects from cowhage tend to be mild and uncommon — mostly diarrhea, gas, and mouth irritation. Some people taking larger doses (around 23–68 grams daily, split into multiple servings) reported nausea, bloating, vomiting, headaches, and insomnia in about 3% of cases.

The product's safety hasn't been thoroughly evaluated, so use it carefully and with professional guidance. The safety data advises against use during pregnancy because there isn't enough data and levodopa's dopamine effects raise concerns.

L-dopa can also lower prolactin levels and reduce milk supply, so avoid this product while breastfeeding.

Side effects, ingredient by ingredient Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking DopaTropic Powder, double-check with your doctor or pharmacist if you take any monoamine oxidase inhibitors (MAOIs) or methyldopa — these carry the highest risk. Also clear it with them if you use other Parkinson's medications (levodopa), antidiabetes drugs, antipsychotics, tricyclic antidepressants, or are facing surgery that requires anesthesia.

If you take guanethidine (Ismelin) for blood pressure, mention this supplement as well.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is for people familiar with levodopa-containing supplements who want a plant-based source and have no Major-risk medications. If you take any prescription drugs — especially blood pressure meds, antidepressants, antipsychotics, diabetes drugs, or have surgery planned — review your full medication list with your doctor or pharmacist before starting.

Not for pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DopaTropic Powder, straight from the product label.

Brand Biotics Research Corporation
Net contents 132 g
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21682
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DopaTropic Powder by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 tsp
Maximum serving Sizes:
2 tsp
Servings per container
30
IngredientAmount% DV
Calories0 {Calories}--
Total Carbohydrates3 g1%
Sugar0 g--
Mucuna pruriens1.6 g--

Other ingredients: Erythritol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Please Recycle

General Statements

35568A FEB 13

Sealed with an imprinted safety seal for your protection.

Suggested/Recommended/Usage/Directions

RECOMMENDATION: One serving (2 teaspoons) each day as a dietary supplement or as otherwise directed by a healthcare professional.

Precautions

Caution: Not recommended for pregnant or lactating women.

Avoid in patients with psychosis or schizophrenia.

Avoid in patients with diabetes and those taking anticoagulants or monoamine oxidase inhibitors.

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry area.

General

Rev. 06/11

Brand IP Statement(s)

(C) Copyright 2011

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

DopaTropic Powder by Biotics Research Corporation label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

DopaTropic Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in DopaTropic Powder by Biotics Research Corporation

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 tsp Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 g per serving

Mucuna pruriens

Interacts with
193 drugs
1.6 g per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna pruriens monograph & interactions

Other (inactive) ingredients: Erythritol. These complete the product’s ingredient list but are not active constituents.

Interaction report

DopaTropic Powder by Biotics Research Corporation Drug Interactions

Want to check YOUR meds against DopaTropic Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
193Drugs
17 Major 176 Moderate

Ingredients driving the most interactions

Mucuna pruriens 193

Individual Drug Interactions

The ingredients in DopaTropic Powder interact with 193 drugs. Click any drug to see the details.

1 of the 2 ingredients in DopaTropic Powder interact with drugs. Each result below shows which ingredient is responsible. Mucuna pruriens

Each ingredient & the kinds of drugs it affects

For each ingredient in DopaTropic Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mucuna pruriens8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna pruriens full monograph & interactions
The maker

Brand information

Manufacturer and brand details for DopaTropic Powder, from the product label.

Biotics Research Corporation

See all Biotics Research Corporation products
Name
BIOTICS RESEARCH CORP.
City
Rosenberg
State
Texas
Phone Number
(281) 344-0909
Pharmacist Counseling Corner

DopaTropic Powder by Biotics Research Corporation: Common Questions

Does DopaTropic Powder by Biotics Research Corporation interact with any medications?
Yes. Based on its ingredients, DopaTropic Powder has a known interaction with 193 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DopaTropic Powder contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No, the safety data advises against it. There isn't enough research to know it's safe, and levodopa's dopamine effects raise concerns during pregnancy. Talk with your doctor before considering this product.
Can I take this while breastfeeding?
No — L-dopa in this product can lower prolactin and reduce milk supply. Avoid it while nursing.
What are the most common side effects?
Diarrhea, gas, and mouth irritation are the main ones, and they're generally rare. At higher doses, nausea, bloating, vomiting, headaches, and insomnia have been reported by a small number of people in trials.
How much levodopa is actually in this powder?
The product facts don't specify the exact amount per dose, but Mucuna pruriens powders are typically standardized to contain 75–400 mg of levodopa per serving. Check your product label or contact the manufacturer for the precise content.
Does this supplement actually work for anything?
In our data, the evidence for Mucuna pruriens is insufficient for any condition — anxiety, Parkinson disease, high prolactin, muscle pain, skin problems, and rheumatoid arthritis all lack reliable proof. Talk to your doctor about whether it's right for your situation.
What's erythritol doing in this product?
Erythritol is a sugar alcohol used as a filler to make the powder easier to mix and take. It's inactive — the levodopa in Mucuna pruriens is the active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DopaTropic Powder label
Go deeper

The Full Monographs Behind DopaTropic Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

DopaTropic Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cowhage 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
  4. HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
  5. Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
  6. Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
  7. Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
  8. Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
  9. Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
  10. Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
  11. Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
  12. Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed

See these in context on the Cowhage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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