Extra Strength Ubiquinol 200 mg Ingredients & Drug Interactions
by Qunol
What is this page for?
First and foremost: checking Extra Strength Ubiquinol 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Extra Strength Ubiquinol 200 mg is a dietary supplement by Qunol with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ubiquinol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Extra Strength Ubiquinol 200 mg by Qunol
Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Ubiquinol 200 mg by Qunol — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Extra Strength Ubiquinol 200 mg by Qunol
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Qunol Extra Strength Ubiquinol 200 mg contains one active ingredient: ubiquinol (also known as coenzyme Q10), a form of a naturally occurring compound your body makes that helps cells produce energy. The softgel also includes inactive ingredients—medium chain triglyceride, gelatin, glycerin, ascorbyl palmitate, purified water, beeswax, sunflower lecithin, and annatto suspension—which serve as the capsule and delivery system.
Does it work?
Strong evidence
Coenzyme Q10 is likely effective for treating coenzyme Q10 deficiency. For other uses, the evidence is more mixed: it's considered possibly effective for fibromyalgia, migraine headache, congestive heart failure (CHF), and diabetic neuropathy.
The data we hold rates these as "possibly effective," meaning there's some research support but the evidence isn't yet conclusive.
How safe is it?
Well-documented data
Coenzyme Q10 is generally well tolerated by most adults when used as directed. In clinical studies, no serious adverse effects have been reported.
The most common side effects are gastrointestinal—appetite suppression, diarrhea, heartburn, nausea, or vomiting—and these occur in less than 1% of people; dividing doses above 100 mg across the day may help. Headache, dizziness, and insomnia have been reported occasionally.
A very small number of people have reported skin itching or allergic rash. For pregnancy, the safety data advises against use unless your doctor advises otherwise.
For breastfeeding, there isn't enough reliable safety data, so talk with your doctor before using this product.
Meds to double-check
Moderate interaction found
Before you take this product, double-check with your doctor or pharmacist if you're on chemotherapy drugs (alkylating agents like cyclophosphamide)—coenzyme Q10 may reduce their effectiveness. If you take warfarin (Coumadin) or another blood thinner, talk with them about whether this supplement is safe for you, as it could weaken blood-thinning effects.
And if you take blood pressure medications, your doctor should know you're adding this, since it may lower blood pressure further.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This supplement is worth considering if you have a coenzyme Q10 deficiency or are interested in its possibly effective uses for heart health, migraines, or nerve pain—but only after you've checked with your doctor or pharmacist, especially if you take blood thinners, chemotherapy, or blood pressure medications. Most people tolerate it well, though mild digestive upset can happen.
Your own doctor or pharmacist can tell you whether it's right for your individual health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Extra Strength Ubiquinol 200 mg, straight from the product label.
| Brand | Qunol |
|---|---|
| Barcode (UPC) | 898440001790 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jan 24, 2024 |
| DSLD ID | 304329 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Extra Strength Ubiquinol 200 mg by Qunol, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 7 Calorie(s) | -- |
| Ubiquinol | 200 mg | -- |
Other ingredients: Medium Chain Triglyceride, Gelatin, Glycerin, Ascorbyl Palmitate, Water, Purified, Beeswax, Sunflower Lecithin, Annatto suspension
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Keep out of reach of children
If you are pregnant or nursing, seek the advice of a healthcare professional before using this product.
Tamper Resistant: Do not use if imprinted safety seal under cap is broken or missing.
Storage
Keep bottle tightly closed. Store in a cool, dry place.
Brand IP Statement(s)
The use of Ascorbyl Palmitate in the formulation is covered by the U.S. Patent No. 6,740,338.
Q+, Kaneka Ubiquinol and the Quality Seal are registered trademarks of Kaneka Corp. Qunol is a registered trademark of Quten Research Institute, LLC
Formulation
Manufactured and packaged in cGMP compliant MD and NY USA facilities with USA and imported ingredients.
Non-GMO. Gluten Free.
Free of: Milk or milk by-products, egg or egg by-products, fish or fish by-products, shellfish or shellfish by-products, tree nuts, wheat or wheat by-products, peanuts or peanut by-products and soybeans or soy by-products.
Seals/Symbols
Kaneka Made with Quality Ingredients
General Statements
Money Back Guarantee. Terms & Conditions Apply. See Qunol.com
Actual Pill Size
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Extra Strength Ubiquinol the active form of CoQ10
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults take one (1) softgel daily with or after a meal, or as directed by your healthcare professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Extra Strength Ubiquinol 200 mg by Qunol label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Extra Strength Ubiquinol 200 mg by Qunol
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Ubiquinol
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Ubiquinol monograph & interactionsOther (inactive) ingredients: Medium Chain Triglyceride, Gelatin, Glycerin, Ascorbyl Palmitate, Water, Purified, Beeswax, Sunflower Lecithin, Annatto suspension. These complete the product’s ingredient list but are not active constituents.
Extra Strength Ubiquinol 200 mg by Qunol Drug Interactions
HelloPharmacist Interaction Report
Qunol Extra Strength Ubiquinol 200 mg can interact with several medication types through its coenzyme Q10 content.
The most serious concern is with chemotherapy drugs called alkylating agents (like cyclophosphamide). Because coenzyme Q10 is an antioxidant, it may theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative damage these drugs rely on.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to be careful if you take warfarin (Coumadin), a blood thinner. Coenzyme Q10 is chemically similar to vitamin K and may have blood-clotting effects that could weaken warfarin's ability to prevent clots.
A small number of cases have been reported where coenzyme Q10 reduced warfarin's effectiveness. Additionally, coenzyme Q10 may have minor additive effects with blood pressure medications (antihypertensive drugs), potentially lowering blood pressure further than intended.
Altogether, these interactions span 198 individual medications. Before you start this product, check your exact medications with the search tool on this page to see if any fall into these categories.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Extra Strength Ubiquinol 200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Extra Strength Ubiquinol 200 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Extra Strength Ubiquinol 200 mg interact with drugs. Each result below shows which ingredient is responsible. Ubiquinol
AltretamineHexalen
How Altretamine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Ubiquinol + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Ubiquinol + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Extra Strength Ubiquinol 200 mg — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Extra Strength Ubiquinol 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ubiquinol
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Extra Strength Ubiquinol 200 mg, from the product label.
Qunol
See all Qunol products- Name
- Quten Research Institute, LLC.
- Street Address
- 10 Bloomfield Avenue - Bldg B
- City
- Pine Brook
- State
- NJ
- ZipCode
- 07058
- Phone Number
- 1-877-290-2621
- Web Address
- qunol.com
Extra Strength Ubiquinol 200 mg by Qunol: Common Questions
Does Extra Strength Ubiquinol 200 mg by Qunol interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is ubiquinol, and why is it in this supplement?
Can I take this if I'm on warfarin or a blood thinner?
Does this supplement actually work for heart health or migraines?
What side effects should I watch for?
Is it safe to take if I'm pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Extra Strength Ubiquinol 200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Extra Strength Ubiquinol 200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Extra Strength Ubiquinol 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
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