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Dietary supplement

Flax-O-Mega Ingredients & Drug Interactions

by Flora

Flax-O-Mega label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Flax-O-Mega against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Flax-O-Mega is a dietary supplement by Flora with 3 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Flax-O-Mega by Flora

Ask about any prescription or over-the-counter medication and we check it for interactions with Flax-O-Mega by Flora — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Flax-O-Mega by Flora

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Flax-O-Mega contains 4 active ingredients, all fatty acids. Oleic acid is a monounsaturated fat; linoleic acid and linolenic acid are polyunsaturated fats that your body needs but can't make on its own.

The product also contains polyunsaturated fat. These are supported by inactive ingredients — flaxseed oil, modified food starch, carrageenan, glycerin, sorbitol, water, and caramel color — that act as binders and preservatives in the softgel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: omega-3 and omega-6 essential fatty acids.
  • We looked for evidence on: Coronary heart disease (CHD), Hypercholesterolemia, Hypertension, Stroke, cardiovascular health, lipid management.
  • The strongest evidence on file: Oleic Acid is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Oleic Acid is rated "Possibly Effective" for Hypercholesterolemia.
  • Also on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Stroke.

Oleic acid is rated possibly effective for lowering cholesterol and supporting heart health, based on the evidence we hold. The other three active ingredients — polyunsaturated fat, linolenic acid, and linoleic acid — have no effectiveness ratings in our data, so we cannot speak to what research shows about their role in this product.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid is generally well tolerated in the amounts found in everyday foods like olive oil. When it comes to concentrated supplement doses, though, the safety data is limited, especially in pregnancy and while breastfeeding.

The research we have is not strong enough to say whether supplement-level amounts are safe during pregnancy or lactation. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antidiabetes drugs (blood sugar medications) before taking Flax-O-Mega — oleic acid may increase how well they work and lower your blood sugar more than expected. We could not check three of the four active ingredients against our database, so if you're on any other medications, your pharmacist can help you search those ingredients individually on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Flax-O-Mega is a fatty-acid blend that may help with cholesterol and heart health, though evidence for the full product is limited. If you take antidiabetes medication, you'll want to check your specific drug before starting, because oleic acid may increase its effect and lower your blood sugar further.

Discuss this product with your doctor or pharmacist, especially if you're pregnant, breastfeeding, or managing any chronic condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flax-O-Mega, straight from the product label.

Brand Flora
Barcode (UPC) 061998614181
Net contents 180 Vegetarian Softgel(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 276592
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flax-O-Mega by Flora, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
90
UPC/BARCODE
061998614181
IngredientAmount% DV
Calories20 Calorie(s)--
Polyunsaturated Fat1.5 Gram(s)--
Total Fat2 Gram(s)3%
Linolenic Acid1100 mg--
Linoleic Acid300 mg--
Oleic Acid300 mg--

Other ingredients: Flaxseed Oil, Food Starch, Modified, Carrageenan, Glycerin, Sorbitol, Water, Caramel color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

The oil in Flax-O-Mega softgels is cold-pressed and unrefined from the highest quality, certified organic flax seeds available.

Flax-O-Mega provides omega-3 (1,100 mg) and omega-6 (300 mg) essential fatty acids (EFAs) per serving. These two EFAs are important for the maintenance of good health. Omega-3 EFA is involved with neurological development and growth.

Premium cold-pressed Flax seed oil Omega 3 & 6

Formulation

It is carefully extracted in a low-heat, light- and oxygen-free environment.

Flora tests every batch of flax seeds to make sure they're free of gluten.

What are GreenCaps? GreenCaps are new and innovative vegetarian softgels that replace animal-based gelatin caps.

Non-GMO Gluten-free

Product of USA

The oil in Flax-O-Mega softgels is cold-pressed and unrefined from the highest quality, certified organic flax seeds available.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Flora Premium herbal formulas

Green caps +

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Precautions

Caution: Manufactured in a facility that also processes mustard and wheat.

Keep out of reach of children.

Security sealed for your protection. Do not use if seal is missing or damaged.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 2 capsules three times a day with meals.

Storage

Store at room temperature.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Flax-O-Mega by Flora label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Flax-O-Mega label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Flax-O-Mega by Flora

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Linolenic Acid

1100 mg per serving

Linoleic Acid

300 mg per serving

Oleic Acid

Interacts with
86 drugs
300 mg per serving

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it...

Oleic Acid monograph & interactions

Other (inactive) ingredients: Flaxseed Oil, Food Starch, Modified, Carrageenan, Glycerin, Sorbitol, Water, Caramel color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flax-O-Mega by Flora Drug Interactions

Want to check YOUR meds against Flax-O-Mega?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Oleic Acid 86

Individual Drug Interactions

The ingredients in Flax-O-Mega interact with 86 drugs. Click any drug to see the details.

1 of the 3 ingredients in Flax-O-Mega interact with drugs. Each result below shows which ingredient is responsible. Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Flax-O-Mega with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Flax-O-Mega, from the product label.

Flora

See all Flora products
Name
Flora, Inc.
Street Address
805 E. Badger Rd.
City
Lynden
State
WA
ZipCode
98264
Phone Number
1.800.446.2110
Web Address
www.florahealth.com
Pharmacist Counseling Corner

Flax-O-Mega by Flora: Common Questions

Does Flax-O-Mega by Flora interact with any medications?
Yes. Based on its ingredients, Flax-O-Mega has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flax-O-Mega contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Flax-O-Mega help with cholesterol?
Oleic acid, one of the active ingredients, is rated possibly effective for lowering cholesterol and supporting heart health. The evidence we hold shows promise, but it's not definitive. Talk with your doctor about whether it fits your cholesterol management plan.
Can I take Flax-O-Mega if I'm pregnant?
The safety of supplement-level doses during pregnancy hasn't been well studied. Food amounts of oleic acid are fine, but concentrated supplements are different. Check with your doctor or pharmacist before taking it if you're pregnant or planning to become pregnant.
What are linolenic acid and linoleic acid for?
Both are polyunsaturated fats your body needs but can't produce on its own — you have to get them from food or supplements. They play a role in cell health and other body functions, but we don't have specific effectiveness ratings for them in our data.
Are there any side effects listed for this product?
No adverse effects are documented in our data for Flax-O-Mega. That doesn't guarantee you won't experience any; if something feels off after you start it, let your pharmacist know.
What's the difference between this and just eating flaxseed or olive oil?
This is a concentrated supplement with specific fatty acids extracted and put into softgels. The amounts are higher than what you'd get from a typical serving of food, which is why the safety data for pregnancy and other situations is thinner than it is for food amounts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flax-O-Mega is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flax-O-Mega label
Go deeper

The Full Monographs Behind Flax-O-Mega’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

Flax-O-Mega's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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