Hawthorn Berry Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hawthorn Berry Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hawthorn Berry Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for heart failure symptoms, high blood pressure, chest pain (angina).Based on those ingredients, 191 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Hawthorn Berry Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hawthorn Berry Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Hawthorn Berry Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hawthorn Berry Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains a single active ingredient: hawthorn berry extract, a concentrate made from the fruit of the hawthorn plant. Hawthorn has a long history in herbal medicine, particularly for heart and circulation support.
The product is delivered as a powder and contains no other inactive ingredients.
Does it work?
Couldn't assess
The evidence for hawthorn's effectiveness is currently insufficient. Our data rates it as having insufficient reliable evidence for angina, anxiety, heart rhythm problems (arrhythmia), atherosclerosis, cardiovascular disease overall, and cognitive function.
That doesn't mean it doesn't work—it means rigorous trials haven't yet established whether and how well it does. If you're considering hawthorn for any of these reasons, talk with your doctor about whether the current evidence supports a trial and how it fits into your overall care.
How safe is it?
Well-documented data
Hawthorn berry extract is generally well tolerated when used as directed, though anyone with a heart condition should use it only under medical supervision. A small number of trial participants reported side effects such as heart palpitations, rapid heartbeat (tachycardia), and shortness of breath; rare cases of serious allergic reactions affecting multiple organs and kidney failure have been reported.
The safety data is not sufficient for pregnancy or breastfeeding, so those are situations to avoid this supplement unless your doctor advises otherwise. If you experience chest pain, severe shortness of breath, or fainting while taking hawthorn, stop and seek medical attention right away.
Meds to double-check
Major interaction found
Before taking hawthorn, double-check it with your doctor or pharmacist if you take nitrates or phosphodiesterase-5 inhibitors (PDE-5 inhibitors) for erectile dysfunction—both carry Major interaction risk and could lower your blood pressure dangerously. Also flag it if you're on beta-blockers, calcium channel blockers, blood thinners (anticoagulants or antiplatelets), or digoxin for your heart.
All are Moderate interactions. The search tool on this page can help you verify your specific medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Hawthorn berry extract may be worth considering if you're interested in heart health support and have discussed it with your doctor—but it's not a substitute for prescribed heart medications. If you take any drugs for blood pressure, heart rhythm, blood thinning, or erectile dysfunction, you need to clear hawthorn with your doctor or pharmacist first because the interactions can be serious.
Pregnant or breastfeeding? Skip it unless your healthcare provider says otherwise.
Talk it over with your own doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hawthorn Berry Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X001HATNH9 |
| Net contents | 250 Gram(s); 8.8 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2023 |
| DSLD ID | 294910 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hawthorn Berry Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BulkSupplements.com Clean & Pure Bulk Supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten, additives
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Storage
Store in a dry, cool place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hawthorn Berry Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hawthorn Berry Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size500 mg Dosage formPowder Servings per container500 Amounts shown are per serving.
Hawthorn Berry Extract
Interacts with191 drugs
Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when...
Hawthorn Berry Extract monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Hawthorn Berry Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Hawthorn Berry Extract by BulkSupplements.com has documented interactions with several medication types, most seriously with nitrates and phosphodiesterase-5 inhibitors (PDE-5 inhibitors—drugs like sildenafil for erectile dysfunction).
Both carry Major severity ratings. With nitrates, hawthorn's blood-vessel-relaxing effects may add to the drug's own effects and potentially drop your blood pressure too far.
The same additive blood-pressure and blood-vessel-widening risk applies to PDE-5 inhibitors.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions are documented with beta-blockers, blood thinners (anticoagulants and antiplatelets), calcium channel blockers, and digoxin (a heart-rhythm medication). Hawthorn may lower blood pressure and heart rate on top of what beta-blockers and calcium channel blockers already do.
With blood thinners, hawthorn might theoretically increase bleeding risk, though its real effect in humans isn't clear. Digoxin is particularly worth watching: hawthorn may strengthen the drug's effects—both wanted and unwanted—though it doesn't change how your body processes the medication itself.
Additionally, the ingredient has been tested for interactions; no other medication types show documented interactions in our data. Altogether, these interactions span 191 individual medications.
Before you start hawthorn, check your exact medications against the search tool on this page or review them with your doctor or pharmacist, especially if you take heart or blood-pressure drugs.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hawthorn Berry Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hawthorn Berry Extract interact with 191 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hawthorn Berry Extract interact with drugs. Each result below shows which ingredient is responsible. Hawthorn Berry Extract
AvanafilStendra
How Avanafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Berry Extract + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Berry Extract + Vardenafil interactionAbciximabReoPro
How Abciximab interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn Berry Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Berry Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmlodipineNorliqva
How Amlodipine interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Berry Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Berry Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Berry Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Berry Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Hawthorn Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Berry Extract + Amlodipine Besylate, Benazepril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hawthorn Berry Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hawthorn Berry Extract
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Brand information
Manufacturer and brand details for Hawthorn Berry Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Hawthorn Berry Extract by BulkSupplements.com: Common Questions
Does Hawthorn Berry Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take hawthorn if I'm pregnant or breastfeeding?
Does hawthorn actually work for heart problems?
What are the side effects?
I'm on a heart medication. Is hawthorn safe to add?
What is hawthorn berry extract?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hawthorn Berry Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hawthorn Berry Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hawthorn Berry Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
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