Healthy Vata Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Healthy Vata against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Healthy Vata is a dietary supplement by Banyan Botanicals with 8 active ingredients. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 1,552 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Ashwagandha, Long Pepper, Indian Tinospora. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Healthy Vata by Banyan Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Healthy Vata by Banyan Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Healthy Vata by Banyan Botanicals
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 8 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 6 of the 7 matched ingredients can interact with medications — Indian Long Pepper, Gotu Kola, Ashwagandha, Cowhage, Tinospora Cordifolia, among others.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium; Parkinson's medications.
- For scale: 1,553 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 5 of the 7 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 7 of 7.
- General safety write-ups exist for 7 of 7.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 7 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Healthy Vata, straight from the product label.
| Brand | Banyan Botanicals |
|---|---|
| Net contents | 90 Tablet(s) |
| Market status | Off market |
| Date entered into DSLD | Apr 25, 2019 |
| DSLD ID | 199638 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Healthy Vata by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1000 mg | -- |
| Gotu Kola | 0 NP | -- |
| Velvet Bean | 0 NP | -- |
| Indian Tinospora | 0 NP | -- |
| Ashwagandha | 0 NP | -- |
| Long Pepper | 0 NP | -- |
| Cardamom | 0 NP | -- |
| Shatavari | 0 NP | -- |
| Finger-leaf Morning Glory | 0 NP | -- |
Other ingredients: organic Rice Flour, organic Gum Acacia
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Ayurvedic herbs Balancing Formula for Vata
Made in USA
Seals/Symbols
USDA Organic
FDA Statement of Identity
Dietary Supplement
Formulation
Certified Organic
Free of gluten, soy and dairy.
100% vegetarian.
Certified Organic by New Mexico Department of Agriculture
Suggested/Recommended/Usage/Directions
Suggested use: Take 1-2 tablets, once or twice daily, or as directed by your health practitioner.
Precautions
If you are pregnant, nursing, taking medications, or have a medical condition please consult with your health care practitioner prior to the use of this product.
Keep out of the reach of children.
Do not use if seal is broken or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place.
General
Rev. 05
Brand IP Statement(s)
2010 Banyan Botanicals
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Healthy Vata by Banyan Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Healthy Vata by Banyan Botanicals
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Gotu Kola
- › Velvet Bean
- › Indian Tinospora
- › Ashwagandha
- › Long Pepper
- › Cardamom
- › Shatavari
- › Finger-leaf Morning Glory
Other (inactive) ingredients: Organic Rice Flour, Organic Gum Acacia. These complete the product’s ingredient list but are not active constituents.
Healthy Vata by Banyan Botanicals Drug Interactions
Healthy Vata contains 8 ingredients, and 6 of them have known drug interactions. Altogether they interact with 1,552 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Healthy Vata?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Healthy Vata interact with 1,552 drugs. Click any drug to see the details.
6 of the 8 ingredients in Healthy Vata interact with drugs. Each result below shows which ingredient is responsible. Ashwagandha Long Pepper Indian Tinospora Gotu Kola Velvet Bean Shatavari
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Amphetamine interactionIndian TinosporaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Indian Tinospora + Amphetamine interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Velvet BeanLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Velvet BeanLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Velvet BeanLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean + Carbidopa, Levodopa, Entacapone interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Healthy Vata — through 4 ingredients. Tap an ingredient for the detail:
Velvet BeanMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean + Chlorothiazide, Methyldopa interactionAshwagandhaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Chlorothiazide, Methyldopa interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Chlorothiazide, Methyldopa interactionShatavariDiuretic Drugs Moderate
Interaction Summary
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Read the full Shatavari + Chlorothiazide, Methyldopa interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Healthy Vata — through 4 ingredients. Tap an ingredient for the detail:
Velvet BeanMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean + Hydrochlorothiazide, Methyldopa interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Hydrochlorothiazide, Methyldopa interactionAshwagandhaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Hydrochlorothiazide, Methyldopa interactionShatavariDiuretic Drugs Moderate
Interaction Summary
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Read the full Shatavari + Hydrochlorothiazide, Methyldopa interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Isocarboxazid interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Isocarboxazid interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Velvet BeanLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Velvet BeanLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Velvet Bean + Levodopa, Carbidopa interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
Velvet BeanMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Velvet Bean + Methyldopa interactionAshwagandhaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Methyldopa interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Methyldopa interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Moclobemide interactionIndian TinosporaCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
Read the full Indian Tinospora + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Healthy Vata — through 4 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Ozanimod Hydrochloride interactionAshwagandhaHepatotoxic Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Ozanimod Hydrochloride interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Ozanimod Hydrochloride interactionIndian TinosporaImmunosuppressants Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
Read the full Indian Tinospora + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Phenelzine Sulfate interactionAshwagandhaCns Depressants, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha + Phenelzine Sulfate interactionGotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Rasagiline interactionIndian TinosporaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Indian Tinospora + Rasagiline interactionAshwagandhaSerotonergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Safinamide Mesylate interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Selegiline interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Velvet BeanMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Velvet Bean + Tranylcypromine interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Tranylcypromine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
Indian TinosporaImmunosuppressants Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
Read the full Indian Tinospora + 6-mercaptopurine interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + 6-mercaptopurine interactionAshwagandhaHepatotoxic Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Long PepperCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Long Pepper + Ado-trastuzumab Emtansine interactionAshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Abacavir Sulfate, Dolutegravir, Lamivudine interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Abacavir, Lamivudine interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Long PepperAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Long Pepper + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Long PepperCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Long Pepper + Abemaciclib interactionAshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
AshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Abiraterone interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abiraterone interactionLong PepperCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Long Pepper + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
Long PepperCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Long Pepper + Abiraterone Acetate interactionAshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Abiraterone Acetate interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Healthy Vata — through 3 ingredients. Tap an ingredient for the detail:
AshwagandhaImmunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Read the full Ashwagandha + Abrocitinib interactionLong PepperAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Long Pepper + Abrocitinib interactionIndian TinosporaCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
Read the full Indian Tinospora + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Long PepperCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Long Pepper + Acalabrutinib interactionAshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Healthy Vata — through 5 ingredients. Tap an ingredient for the detail:
Long PepperAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Long Pepper + Acarbose interactionGotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acarbose interactionAshwagandhaHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Acarbose interactionIndian TinosporaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Indian Tinospora + Acarbose interactionVelvet BeanAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Velvet Bean + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Healthy Vata — through 2 ingredients. Tap an ingredient for the detail:
Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola + Acebutolol interactionAshwagandhaHepatotoxic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Healthy Vata — through 1 ingredient. Tap an ingredient for the detail:
Long PepperAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Long Pepper + Acenocoumarol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Healthy Vata with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Ashwagandha
Antidiabetes Drugs
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.
Antihypertensive Drugs
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Benzodiazepines
Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.
Cns Depressants
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.
Hepatotoxic Drugs
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.
Immunosuppressants
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.
Thyroid Hormone
Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.
Serotonergic Drugs
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]
Long Pepper
Anticoagulant/Antiplatelet Drugs
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that Indian long pepper extract inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of Indian long pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cyclosporine (Neoral, Sandimmune)
Theoretically, Indian long pepper might increase the effects and adverse effects of cyclosporine.
In vitro research shows that piperine, a constituent of Indian long pepper, increases the bioavailability of cyclosporine.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, inhibits CYP3A4.
Nevirapine (Viramune)
Theoretically, Indian long pepper might increase blood levels of nevirapine.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases the plasma concentration and systemic exposure of nevirapine. However, no adverse effects were associated with the elevated plasma levels of nevirapine.
P-Glycoprotein Substrates
Theoretically, Indian long pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, can inhibit P-glycoprotein.
Pentobarbital (Nembutal)
Theoretically, Indian long pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of Indian long pepper, can increase pentobarbitone-induced sleeping time.
Phenytoin (Dilantin)
Theoretically, Indian long pepper might increase blood levels of phenytoin.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases phenytoin serum levels and slows its elimination.
Propranolol (Inderal)
Theoretically, Indian long pepper might increase blood levels of propranolol.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, accelerates absorption and increases serum concentrations of propranolol.
Rifampin (Rifadin)
Theoretically, Indian long pepper might increase blood levels of rifampin.
Piperine, a constituent of Indian long pepper, seems to increase absorption and serum levels of rifampin.
Theophylline
Indian long pepper might increase blood levels of theophylline.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases serum concentrations and slows elimination of theophylline.
Amoxicillin (Amoxil, Trimox)
Theoretically, Indian long pepper might increase the effects and adverse effects of amoxicillin.
Evidence from animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of amoxicillin when taken concomitantly.
Carbamazepine (Tegretol)
Theoretically, Indian long pepper might increase blood levels of carbamazepine.
A small pharmacokinetic study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that a single 20 mg dose of purified piperine, which is a constituent of Indian long pepper, increases carbamazepine levels. Piperine may increase absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or by cytochrome P450 3A4 (CYP3A4) inhibition in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects.
Cefotaxime (Claforan)
Theoretically, Indian long pepper might increase the effects and adverse effects of cefotaxime.
Animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of cefotaxime when taken concomitantly.
Indian Tinospora
Antidiabetes Drugs
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.
Gotu Kola
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
Velvet Bean
Levodopa
Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.
Methyldopa (Aldomet)
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.
Anesthesia
Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.
Antidiabetes Drugs
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.
Antipsychotic Drugs
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.
Guanethidine (Ismelin)
Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.
Tricyclic Antidepressants (Tcas)
Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.
Shatavari
Diuretic Drugs
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.
Lithium
Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Healthy Vata, from the product label.
Banyan Botanicals
See all Banyan Botanicals products- Name
- Banyan Botanicals
- City
- Albuquerque
- State
- NM
- ZipCode
- 87113
- Phone Number
- 1-800-953-6424
- Web Address
- www.banyanbotanicals.com
Healthy Vata by Banyan Botanicals: Common Questions
Does Healthy Vata by Banyan Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Healthy Vata’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Gotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph → Herb & supplement monographCowhage
Interacts with 193 drugsCowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...
Read the full Cowhage monograph → Herb & supplement monographTinospora Cordifolia
Interacts with 612 drugsTinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...
Read the full Tinospora Cordifolia monograph → Herb & supplement monographAshwagandha
Interacts with 1,372 drugsAshwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...
Read the full Ashwagandha monograph → Herb & supplement monographIndian Long Pepper
Interacts with 896 drugsIndian long pepper (pippali) is a spice long used in Ayurvedic medicine and is best known for its piperine content, which may increase how well the body absorbs certain other substances. Mod...
Read the full Indian Long Pepper monograph → Herb & supplement monographCardamom
Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements...
Read the full Cardamom monograph → Herb & supplement monographAsparagus Racemosus
Interacts with 76 drugsAsparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...
Read the full Asparagus Racemosus monograph →Sources & How We Checked
Healthy Vata's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 93 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Gotu Kola 18 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
- Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
- Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
- Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
- Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
- Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
- Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
- Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
- Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
- Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
- Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
- Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
- Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
- Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
- Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
- Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
- Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed
Cowhage 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
- HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
- Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
- Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
- Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
- Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
- Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
- Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
- Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
- Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed
Tinospora Cordifolia 16 references
- Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
- Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
- Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
- Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
- Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
- Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
- Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
- Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
- Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
- Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
- Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
- Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
- Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
- May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.
See these in context on the Tinospora Cordifolia monograph →
Ashwagandha 32 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
- Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
- Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
- Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
- Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
- Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
- Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
- Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
- Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
- Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
- Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
- Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
- Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
- Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
- Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
- Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
- Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
- Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
- Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
- Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
- Ajgaonkar A, Jain M, Debnath K. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus 2022;14(10):e30787. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Lubarska M, Halasinski P, Hryhorowicz S, et al. Liver Dangers of Herbal Products: A Case Report of Ashwagandha-Induced Liver Injury. Int J Environ Res Public Health 2023;20(5):3921. PubMed
- Tóth M, Benedek AE, Longerich T, Seitz HK. Ashwagandha-induced acute liver injury: A case report. Clin Case Rep 2023;11(3):e7078.
- Bokan G, Glamocanin T, Mavija Z, et al. Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause. Pharmaceuticals (Basel) 2023;16(8):1129. PubMed
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