HLC Maintenance Ingredients & Drug Interactions
by Pharmax
What is this page for?
First and foremost: checking HLC Maintenance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HLC Maintenance is a dietary supplement by Pharmax with 4 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Bifidobacterium bifidum CUL-20. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against HLC Maintenance by Pharmax
Ask about any prescription or over-the-counter medication and we check it for interactions with HLC Maintenance by Pharmax — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of HLC Maintenance by Pharmax
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
HLC Maintenance contains 4 active ingredients: Fructooligosaccharides (a type of fiber that feeds beneficial gut bacteria), Lactobacillus acidophilus (a live probiotic strain), Bifidobacterium bifidum CUL-20 (another live probiotic strain), and HLC Consortium (a proprietary blend of additional probiotic organisms). The capsules also contain inactive ingredients—cellulose, hypromellose, sunflower lecithin, and silica—which are binders, coatings, and flow agents.
Does it work?
Moderate evidence
The probiotics in this product—Lactobacillus acidophilus and Bifidobacterium bifidum—are rated Possibly Effective for irritable bowel syndrome (IBS). L. acidophilus is also Possibly Effective for antibiotic-associated diarrhea and bacterial vaginosis.
Bifidobacterium bifidum is Possibly Effective for respiratory tract infections. The evidence for Fructooligosaccharides and several other conditions is insufficient to rate, meaning the data we hold doesn't establish whether they work for osteoporosis, constipation, diabetes, travelers' diarrhea, or high cholesterol.
Talk to your doctor about whether this product fits your specific health goals.
How safe is it?
Well-documented data
Both Lactobacillus acidophilus and Bifidobacterium bifidum are generally well tolerated in healthy adults and children. The main side effects from probiotics are mild: bloating, flatulence, abdominal pain, and occasionally burping or diarrhea when first starting—these are uncommon and usually settle down.
Fructooligosaccharides can cause gas and bloating, especially at higher doses, though clinical trials suggest doses under 10 grams daily are often no worse than placebo. For pregnancy, Lactobacillus acidophilus is rated Possibly Safe.
Bifidobacterium bifidum is also rated Possibly Safe in pregnancy. The safety data for Fructooligosaccharides in pregnancy isn't on file—there isn't enough information to know either way.
People with weakened immune systems should check with their doctor before taking probiotics, since live organisms carry a small theoretical risk in that population. Talk to your doctor or pharmacist about whether this product is right for your situation.
Meds to double-check
Moderate interaction found
Before taking HLC Maintenance, double-check with your doctor or pharmacist if you're on antibiotic drugs. The live probiotics in this product can be killed by antibiotics, making both less effective; timing them several hours apart usually solves this.
No other medication interactions are documented for the ingredients we could check.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
HLC Maintenance is a multi-strain probiotic intended to support gut health, with evidence suggesting benefit for IBS and some digestive conditions. If you take antibiotics, space them apart from this product—ask your doctor or pharmacist for the right timing.
Check your full medication list with your healthcare provider before starting, and let them know if you have a weakened immune system.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HLC Maintenance, straight from the product label.
| Brand | Pharmax |
|---|---|
| Barcode (UPC) | 883196202812 |
| Net contents | 120 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 288291 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HLC Maintenance by Pharmax, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fructooligosaccharides | 100 mg | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Bifidobacterium bifidum CUL-20 | 0 NP | -- |
| HLC Consortium | 0 NP | -- |
| Bifidobacterium animalis lactis CUL-34 | 0 NP | -- |
Other ingredients: Cellulose, Hypromellose, Sunflower Lecithin, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Human Lactic Commensals (HLC) probiotics have been extensively researched, including randomized, placebo-controlled human clinical trials. These proprietary strains are compatible with the human gastrointestinal tract and are selected based on their high quality and viability.
Research Driven Probiotics
Suggested/Recommended/Usage/Directions
Recommended intake: Adults, adolescents and children (6 years and older): One capsule taken 1-2 times daily with meals or as professionally directed.
Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Caution: If you are immunocompromised, consult your health professional before using probiotic-containing products. Use only if safety seal is intact.
Keep out of the reach of children.
Storage
Store under refrigeration (below 46 degrees F).
General Statements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Formulation
Supports gastrointestinal health
Gluten free and Dairy free
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Probiotic Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HLC Maintenance by Pharmax label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HLC Maintenance by Pharmax
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Fructooligosaccharides
No knowninteractions
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...
Fructooligosaccharides monograph & interactionsHLC Consortium
- › Lactobacillus acidophilus
- › Bifidobacterium bifidum CUL-20
- › Bifidobacterium animalis lactis CUL-34
Other (inactive) ingredients: Cellulose, Hypromellose, Sunflower Lecithin, Silica. These complete the product’s ingredient list but are not active constituents.
HLC Maintenance by Pharmax Drug Interactions
HelloPharmacist Interaction Report
HLC Maintenance by Pharmax contains probiotics, and through its Lactobacillus acidophilus and Bifidobacterium bifidum content, it has a documented interaction with antibiotic drugs.
Both probiotics are live organisms that antibiotics can kill, potentially making the probiotic less effective. This is a Moderate-severity interaction, but it's manageable by spacing out when you take them.
Read the full breakdown — every affected drug type, severity by severity
The product also contains Fructooligosaccharides, which we checked and found no documented interactions with medications. We don't hold interaction data for Bifidobacterium animalis lactis CUL-34, so we cannot verify whether it interacts with any drugs.
Altogether, these interactions span 182 individual medications.
If you take antibiotics, talk to your doctor or pharmacist about timing—they may recommend taking the probiotic a few hours apart from your antibiotic dose. Before you start this product, run your exact medications through the tool on this page to see if anything else applies to you.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against HLC Maintenance?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in HLC Maintenance interact with 182 drugs. Click any drug to see the details.
2 of the 4 ingredients in HLC Maintenance interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Bifidobacterium bifidum CUL-20
AmikacinAmikin, Arikayce
How Amikacin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amikacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin Veterinary interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Amphotericin, Tetracycline interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin, Sulbactam interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Avibactam Sodium, Ceftazidime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Azithromycin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Aztreonam interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacampicillin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacitracin interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Benznidazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Capreomycin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Carbenicillin Indanyl Sodium interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefaclor interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefadroxil interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefamandole interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefazolin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefdinir interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefditoren Pivoxil interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefepime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefiderocol Sulfate Tosylate interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefixime interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefmetazole interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefonicid interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefoperazone interactionBifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with HLC Maintenance — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum Cul-20Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum Cul-20 + Cefotaxime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in HLC Maintenance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Bifidobacterium bifidum CUL-20
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
Brand information
Manufacturer and brand details for HLC Maintenance, from the product label.
Pharmax
See all Pharmax products- Name
- Seroyal USA
- City
- Pittsburg
- State
- PA
- ZipCode
- 15275
- Phone Number
- 1-888-737-6925
HLC Maintenance by Pharmax: Common Questions
Does HLC Maintenance by Pharmax interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on antibiotics?
Is this safe in pregnancy?
What are the main side effects?
Will this help with IBS?
Is there filler in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if HLC Maintenance is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind HLC Maintenance’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fructo-oligosaccharides (fos)
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...
Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph →Sources & How We Checked
HLC Maintenance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fructo-oligosaccharides (fos) 6 references
- Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
- Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
- Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
- Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed
See these in context on the Fructo-oligosaccharides (fos) monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC