Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

HLC Maternity Ingredients & Drug Interactions

by Pharmax

HLC Maternity label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking HLC Maternity against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

HLC Maternity is a dietary supplement by Pharmax with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Consortium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against HLC Maternity by Pharmax

Ask about any prescription or over-the-counter medication and we check it for interactions with HLC Maternity by Pharmax — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of HLC Maternity by Pharmax

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Probiotic Consortium” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

HLC Maternity is a four-ingredient probiotic formula designed for pregnancy and postpartum use. It contains live beneficial bacteria: Lactobacillus paracasei, Bifidobacterium animalis subsp. lactis, Bifidobacterium bifidum, and Lactobacillus salivarius.

Each strain is a different type of 'good bacteria' that naturally live in your gut. The capsules also contain two inactive ingredients — potato maltodextrin (a starch-based filler) and hypromellose (the capsule material itself).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports gastrointestinal health and microflora.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Dysbiosis — and 3 related terms.
  • The strongest evidence on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

The Bifidobacterium animalis subsp. lactis in this formula has been rated possibly effective for respiratory tract infections, irritable bowel syndrome (IBS), and constipation. Bifidobacterium bifidum is possibly effective for IBS and respiratory tract infections.

For other uses — like hay fever, Alzheimer disease, and anxiety — the evidence we hold on Bifidobacterium bifidum is insufficient to rate it. We don't have effectiveness data on file for the Lactobacillus strains in this product.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Animalis Subsp. Lactis Bifidobacterium Bifidum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Bifidobacterium ingredients are generally well tolerated by healthy people when taken as directed. The most common side effect reported with Bifidobacterium animalis subsp. lactis is diarrhea; bloating, flatulence, stomach discomfort, and constipation have been reported rarely.

Bifidobacterium bifidum is generally well tolerated, though bloating and flatulence may occur with probiotic use generally. Rare serious concerns include a theoretical risk of infection in people with weakened immune systems, so those with compromised immunity should discuss this product with their doctor first.

For pregnancy, Bifidobacterium bifidum is rated possibly safe. We don't have pregnancy or lactation data on file for the other three ingredients.

If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting this formula.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Animalis Subsp. Lactis Bifidobacterium Bifidum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bifidobacterium Animalis Subsp. Lactis, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start HLC Maternity, check your antibiotic medications — if you're taking any, you'll need to space them several hours apart from this supplement. Antibiotic drugs are the only medication type we have documented interactions for with the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

HLC Maternity is a probiotic blend aimed at supporting digestive and immune health during pregnancy and after delivery, with two ingredients rated possibly effective for IBS and respiratory infections. The main thing to watch: if you're taking antibiotics, separate them from this supplement by several hours, since the antibiotics can kill the live bacteria you're trying to take.

Talk with your doctor or pharmacist about whether this product is right for you and how to time it around any medications you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HLC Maternity, straight from the product label.

Brand Pharmax
Barcode (UPC) 883196214716
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 238924
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Pregnant Women, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HLC Maternity by Pharmax, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Pregnant and Lactating
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
883196214716
IngredientAmount% DV
Lactobacillus paracasei (CUL-08)0 NP--
Bifidobacterium animalis subsp. lactis (CUL-34)0 NP--
Bifidobacterium bifidum (CUL-20)0 NP--
Lactobacillus salivarius (CUL-61)0 NP--
Probiotic Consortium0 NP--

Other ingredients: Potato Maltodextrin, Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Human Lactic Commensals (HLC) probiotics have been extensively researched, including randomized, placebo-controlled human clinical trials. These proprietary strains are compatible with the human gastrointestinal tract and are selected based on their high quality and viability.

Research driven probiotics

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Probiotic Supplement

Formulation

Supports gastrointestinal health and a healthy microflora

Gluten free, dairy free and FOS free

Suggested/Recommended/Usage/Directions

Recommended Intake: Women: One capsule taken daily with a meal or as professionally directed.

Precautions

Warning: If you have an immune-compromised condition, do not use.

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

If symptoms of digestive upset occur, stop use and consult your health professional. This product was sealed for your protection. Do not use if box or contents are open or damaged.

Keep out of the reach of children.

Storage

Store under refrigeration (below 46 degrees F).

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

HLC Maternity by Pharmax label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

HLC Maternity label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in HLC Maternity by Pharmax

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Probiotic Consortium

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Consortium monograph & interactions

Other (inactive) ingredients: Potato Maltodextrin, Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

HLC Maternity by Pharmax Drug Interactions

Want to check YOUR meds against HLC Maternity?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Probiotic Consortium 182

Individual Drug Interactions

The ingredients in HLC Maternity interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in HLC Maternity interact with drugs. Each result below shows which ingredient is responsible. Probiotic Consortium

Each ingredient & the kinds of drugs it affects

For each ingredient in HLC Maternity with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Consortium1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Consortium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for HLC Maternity, from the product label.

Pharmax

See all Pharmax products
Name
Seroyal USA
City
Pittsburg
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

HLC Maternity by Pharmax: Common Questions

Does HLC Maternity by Pharmax interact with any medications?
Yes. Based on its ingredients, HLC Maternity has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HLC Maternity contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Bifidobacterium bifidum, one of the four probiotics in this formula, is rated possibly safe in pregnancy. We don't have enough data to say either way for the other three ingredients. Talk with your doctor or pharmacist before starting it — they can weigh the potential benefit against what they know about your pregnancy and give you personalized advice.
Is it safe to take with antibiotics?
Not at the same time. Antibiotics can kill the live bacteria in this product, which defeats the purpose. If you're prescribed antibiotics, ask your doctor or pharmacist how many hours to wait between taking your antibiotic and this probiotic — usually it's at least a few hours apart.
What side effects might I notice?
Diarrhea is the most commonly reported side effect. Bloating, flatulence, stomach discomfort, and constipation have also been reported, but are less common. Most people tolerate these probiotics well when taken as directed.
Does this product contain any fillers?
Yes — it has potato maltodextrin (a starch-based filler) and hypromellose (the capsule itself). The four active ingredients are the live bacteria; everything else is used to make the capsule and keep the formula stable.
What are these probiotics supposed to do?
The two Bifidobacterium strains in here have been rated possibly effective for irritable bowel syndrome, respiratory tract infections, and constipation. We don't have established effectiveness data for the two Lactobacillus strains in our current information.
Can I take this while breastfeeding?
We don't have safety data on file for the ingredients in this product during lactation. Talk with your doctor or pharmacist before starting it — they can advise you based on your individual situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if HLC Maternity is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HLC Maternity label
Go deeper

The Full Monographs Behind HLC Maternity’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Animalis Subsp. Lactis

Interacts with 182 drugs

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut health. It appears generally safe for most...

Read the full Bifidobacterium Animalis Subsp. Lactis monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph →
Sources

Sources & How We Checked

HLC Maternity's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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