Horebound Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Horebound Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Horebound Extract is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horehound Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Horebound Extract by Nature's Answer
Ask about any prescription or over-the-counter medication and we check it for interactions with Horebound Extract by Nature's Answer — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Horebound Extract by Nature's Answer
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — White Horehound.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: diabetes medications.
- For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Horebound Extract, straight from the product label.
| Brand | Nature's Answer |
|---|---|
| Barcode (UPC) | 083000003523 |
| Net contents | 1 fl. Oz.; 30 mL |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 264005 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Horebound Extract by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Horehound Aerial Parts Extract | 500 mg | -- |
Other ingredients: purified Water, Vegetable Glycerin, certified organic Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Gluten Free
12-15% Certified Organic Alcohol.
Our alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the plant.
Seals/Symbols
K Parve (Kosher)
Bio-Chelated Cold Extraction Process
Formula
K Parve (Kosher)
Marrubium vulgare Made from 2,000mg horehound aerial parts per serving
Low Alcohol
Brand IP Statement(s)
Nature's Answer Since 1972
Discover Nature's Answer
Copyright 2019 Nature's Answer
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement take 1-2 mL (28-56 drops) three (3) times a day in a small amount of water. Shake well.
Precautions
Keep out of reach of children.
Warning: Do not use if pregnant or nursing.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Horebound Extract by Nature's Answer label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Horebound Extract by Nature's Answer
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.
Horehound Aerial Parts Extract
Interacts with258 drugs
White horehound is a traditional bitter herb used mainly for coughs, sore throats, and mild digestive complaints, and it is a common flavoring in old-...
Horehound Aerial Parts Extract monograph & interactionsOther (inactive) ingredients: Purified Water, Vegetable Glycerin, Certified organic Alcohol. These complete the product’s ingredient list but are not active constituents.
Horebound Extract by Nature's Answer Drug Interactions
Horebound Extract contains a single active ingredient, and it has known interactions with 258 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Horebound Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Horebound Extract interact with 258 drugs. Click any drug to see the details.
1 of the 1 ingredient in Horebound Extract interact with drugs. Each result below shows which ingredient is responsible. Horehound Aerial Parts Extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Ammonium Chloride interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that white horehound might lower blood glucose.
Read the full Horehound Aerial Parts Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAprocitentanTryvio
How Aprocitentan interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Horebound Extract — through 1 ingredient. Tap an ingredient for the detail:
Horehound Aerial Parts ExtractAntihypertensive Drugs Moderate
Interaction Summary
Evidence from animal research suggests that taking white horehound extract lowers blood pressure.
Read the full Horehound Aerial Parts Extract + Bendroflumethiazide, Nadolol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Horebound Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Horehound Aerial Parts Extract
Antidiabetes Drugs
Evidence from animal research suggests that white horehound might lower blood glucose. However, preliminary clinical research suggests that white horehound only slightly lowers blood glucose when taken in combination with antidiabetic agents, suggesting that the effect may not be clinically significant. Until more is known, use with caution. Theoretically, white horehound may have additive effects when used by patients taking antidiabetic drugs. The dose of diabetes medications might need to be adjusted. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
Antihypertensive Drugs
Evidence from animal research suggests that taking white horehound extract lowers blood pressure. Theoretically, taking white horehound with antihypertensive drugs might enhance therapeutic effects and increase the risk of hypotension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Brand information
Manufacturer and brand details for Horebound Extract, from the product label.
Nature's Answer
See all Nature's Answer products- Name
- Nature's Answer
- Street Address
- 85 Commerce Drive
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- (800) 439-2324
- Web Address
- www.naturesanswer.com
Horebound Extract by Nature's Answer: Common Questions
Does Horebound Extract by Nature's Answer interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Horebound Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Horebound Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Horebound Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
White Horehound 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Roman, Ramos R., Alarcon-Aguilar, F., Lara-Lemus, A., and Flores-Saenz, J. L. Hypoglycemic effect of plants used in Mexico as antidiabetics. Arch.Med.Res 1992;23:59-64.
- Novaes AP, Rossi C, Poffo C, et al. Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants. Therapie. 2001;56(4):427-30.
- El Bardai, S., Lyoussi, B., Wibo, M., and Morel, N. Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat. Clin Exp Hypertens. 2001;23(4):329-343.
- El Bardai, S., Lyoussi, B., Wibo, M., and Morel, N. Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat. Clin Exp Hypertens. 2004;26(6):465-474 PubMed
- Herrera-Arellano, A., Aguilar-Santamaria, L., Garcia-Hernandez, B., Nicasio-Torres, P., and Tortoriello, J. Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics. Phytomedicine 200 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC