Joint Formula By Dr. Mercola Overview & Drug Interactions

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

Astaxanthin is a naturally occurring carotenoid, a class of pigments found in a variety of plants and microorganisms. It is known for its strong antioxidant properties and for giving certain seafood and other organisms their pink or red color. Astaxanthin is commonly used as a dietary supplement and can be found in the form of capsules, tablets, and soft gels. It is promoted for its potential health benefits, including reducing the risk of heart disease, improving skin health, and reducing inflammation. Astaxanthin is a common component in dietary supplements for the eye, marketed to reduce the effects of age-related macular degeneration (AMD).