Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Just Relax Watermelon Ingredients & Drug Interactions

by Pure TheraPro Rx

Just Relax Watermelon label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Just Relax Watermelon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Just Relax Watermelon is a dietary supplement by Pure TheraPro Rx with 5 active ingredients. Its ingredients are commonly taken for exercise performance and endurance, heart health, energy support.Based on those ingredients, 880 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Suntheanine, Gamma-Aminobutyric Acid, Magnesium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Just Relax Watermelon by Pure TheraPro Rx

Ask about any prescription or over-the-counter medication and we check it for interactions with Just Relax Watermelon by Pure TheraPro Rx — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Just Relax Watermelon by Pure TheraPro Rx

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Just Relax Watermelon is a powder with five active ingredients. Taurine is an amino acid that may support heart and liver function.

Magnesium is a mineral involved in muscle and nerve function. Suntheanine (theanine) is a compound from tea that research suggests may help with focus and calm.

GABA is a neurotransmitter thought to promote relaxation. Myo-inositol is a carbohydrate form that may support metabolic and reproductive health.

The product also contains inactive ingredients—citric acid, malic acid, watermelon flavor, monk fruit extract, and red beet powder—which serve as the base, sweetener, and flavoring.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support stress response and calm relaxation.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Depression, stress management, nervousness, restlessness.
  • The closest evidence on file: Inositol is rated "Possibly Ineffective" for Anxiety (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Depression.
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Depression.

The evidence for this product's ingredients is mixed. Magnesium is effective for constipation and for correcting low magnesium levels (hypomagnesemia).

Taurine is possibly effective for congestive heart failure and hepatitis. Theanine has possibly effective evidence for cognitive function, but evidence for anxiety is insufficient.

GABA's effectiveness for anxiety, ADHD, and other conditions listed has not been reliably established in the data we hold. Myo-inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome, but possibly ineffective for anxiety and depression.

Overall, if you're looking for a relaxation product, the evidence supporting these specific ingredients for that purpose is not clearly established.

The evidence, ingredient by ingredient Taurine Magnesium Theanine Gamma-aminobutyric Acid (gaba) Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Magnesium and taurine are generally well tolerated short-term, though long-term safety for taurine is less certain. Common side effects include diarrhea, constipation, nausea, and digestive upset.

Theanine and GABA are also generally well tolerated but lack long-term safety data. Reported side effects of theanine include headaches and drowsiness.

GABA may cause drowsiness, muscle weakness, or nausea. Myo-inositol is generally well tolerated with mostly mild digestive side effects.

Rare serious adverse effects are possible with any ingredient—taurine has been linked to allergic reactions in sensitive individuals, and magnesium in very high doses over long periods may affect bone health. This product has not been studied in pregnancy or breastfeeding; theanine and GABA should be avoided during pregnancy and lactation due to insufficient safety data.

Magnesium is needed in pregnancy but supplements should be used only under your doctor's guidance. Talk with your doctor or pharmacist about whether this product is appropriate for you.

Side effects, ingredient by ingredient Taurine Magnesium Theanine Gamma-aminobutyric Acid (gaba) Inositol

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Inositol, Gamma-aminobutyric Acid (gaba), Magnesium, Taurine, Theanine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 880 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take Parkinson's medications (especially levodopa/carbidopa), blood pressure drugs, diabetes medications, skeletal muscle relaxants, potassium-sparing diuretics, calcium channel blockers, lithium, quinolone antibiotics, bisphosphonate osteoporosis drugs, sleep aids or other CNS depressants, or acid-reducing medications. Magnesium can significantly reduce how well some of these work, and taurine and theanine may intensify blood pressure effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Just Relax Watermelon may appeal to people looking for a multiingredient relaxation supplement, though the evidence supporting its ingredients for relaxation specifically is not well established. If you take blood pressure medications, Parkinson's drugs, diabetes medications, or antibiotics—or if you're pregnant or breastfeeding—talk with your doctor or pharmacist before starting it.

Check your exact medications against the interactions list on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Just Relax Watermelon, straight from the product label.

Brand Pure TheraPro Rx
Barcode (UPC) X0034OC9TP
Net contents 234 Gram(s); 8.3 Ounce(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 305953
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Children (All), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Just Relax Watermelon by Pure TheraPro Rx, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.9 Gram(s)
Maximum serving Sizes:
3.9 Gram(s)
Servings per container
60
UPC/BARCODE
X0034OC9TP
IngredientAmount% DV
Taurine500 mg--
Magnesium80 mg19%
Suntheanine55 mg--
Gamma-Aminobutyric Acid100 mg--
Myo-Inositol2 Gram(s)--

Other ingredients: Citric Acid, Malic Acid, Watermelon Flavor, Monk Fruit Extract, Red Beet, Natural, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Dissolve one (1) scoop with 6 fl oz of water. Drink one to four times daily, or as directed by a healthcare practitioner.

Precautions

Warning: Individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use.

Warning: individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use.

Do not use if tamper seal is damaged.

Keep out of reach of children.

Formula

Just Relax is a convenient watermelon-flavored drink mix formulated with advanced nutraceuticals that support an optimal stress response and a sense of profound calm and relaxation for adults and children alike. Subtly flavored with watermelon and monk fruit extract, Just Relax is a delicious way to support your brain and adrenals in dealing with the rigors of the day and the acute chronic stress that accompany them.

Suntheanine

Monk fruit sweetened

Kid friendly

Storage

Storage: Keep tightly closed in a cool, dry place.

Formulation

Formulated to exclude: Fillers, gluten, wheat, soy, corn, yeast, animal or dairy products, shellfish, fish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMO's), artificial preservatives, sweeteners or colors.

Please note: Due to the botanical nature of this product, variations in aroma, color and taste may occur.

Promotes a calm state of body & mind

Vegan

Formulated, tested & packaged in the USA

Brand IP Statement(s)

Suntheanine is the patented form of L-theanine and the trademark of Taiyo International, Inc.

Pure TheraPro RX Purity is priority

Albion is a registered trademark of Albion laboratories, Inc. Malate covered by U.S. Patent 6,706,904. Copyright 2023 Pure TheraPro RX

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Certified Good Manufacturing Practice

FDA Statement of Identity

Professional Dietary Supplement

General Statements

Please recycle

New

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Just Relax Watermelon by Pure TheraPro Rx label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Just Relax Watermelon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Just Relax Watermelon by Pure TheraPro Rx

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.9 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Taurine

Interacts with
173 drugs
500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions

Magnesium

Interacts with
295 drugs
80 mg per serving Form: Albion Dimagnesium Malate

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Suntheanine

Interacts with
565 drugs
55 mg per serving Form: L-Theanine

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

Suntheanine monograph & interactions

Gamma-Aminobutyric Acid

Interacts with
419 drugs
100 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma-Aminobutyric Acid monograph & interactions

Myo-Inositol

Interacts with
86 drugs
2 Gram(s) per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Myo-Inositol monograph & interactions

Other (inactive) ingredients: Citric Acid, Malic Acid, Watermelon Flavor, Monk Fruit Extract, Red Beet, Natural, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Just Relax Watermelon by Pure TheraPro Rx Drug Interactions

Want to check YOUR meds against Just Relax Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
880Drugs
6 Major 399 Moderate 475 Minor

Ingredients driving the most interactions

Suntheanine 565
Gamma-Aminobutyric Acid 419
Magnesium 295
Taurine 173
Myo-Inositol 86

Individual Drug Interactions

The ingredients in Just Relax Watermelon interact with 880 drugs. Click any drug to see the details.

5 of the 5 ingredients in Just Relax Watermelon interact with drugs. Each result below shows which ingredient is responsible. Suntheanine Gamma-Aminobutyric Acid Magnesium Taurine Myo-Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Just Relax Watermelon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Suntheanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C
Suntheanine full monograph & interactions

Gamma-Aminobutyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma-Aminobutyric Acid full monograph & interactions

Magnesium15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B
Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D
Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B
Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D
Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B
Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D
Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D
Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A
Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B
Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B
Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B
Magnesium full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

Myo-Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Myo-Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Just Relax Watermelon, from the product label.

Pure TheraPro Rx

See all Pure TheraPro Rx products
Name
Pure TheraPro Rx
Street Address
8781 Sheridan Blvd #6080
City
Westminster
State
CO
ZipCode
80003
Phone Number
888-655-4648
Web Address
Purethera.com
Pharmacist Counseling Corner

Just Relax Watermelon by Pure TheraPro Rx: Common Questions

Does Just Relax Watermelon by Pure TheraPro Rx interact with any medications?
Yes. Based on its ingredients, Just Relax Watermelon has a known interaction with 880 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Just Relax Watermelon contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is this powder supposed to do?
It's marketed as a relaxation supplement containing taurine, magnesium, theanine, GABA, and myo-inositol—ingredients traditionally associated with calm and muscle ease. However, the clinical evidence specifically supporting these ingredients as a relaxation blend is not clearly established in the data we hold.
Can I take this if I'm on blood pressure medication?
Both taurine and theanine may lower blood pressure, so combining them with blood pressure drugs could increase that effect too much. Check with your doctor or pharmacist about your specific medications before starting.
Is this safe during pregnancy?
No. Theanine and GABA should be avoided in pregnancy due to insufficient safety data. Magnesium is needed in pregnancy, but only your doctor should decide whether a supplement is right for you. Talk with your doctor before use.
What are the most common side effects?
Gastrointestinal upset—diarrhea, nausea, constipation, gas—is most common across these ingredients. Theanine and GABA may also cause drowsiness or headaches.
Will this interact with my diabetes medication?
Myo-inositol may lower blood sugar, and magnesium may increase the effect of sulfonylurea diabetes drugs, raising the risk of low blood sugar (hypoglycemia). Check with your doctor or pharmacist before combining this product with any diabetes medication.
Can I take this with antibiotics?
Magnesium can bind to quinolone antibiotics (like ciprofloxacin) and reduce how well they're absorbed. If you're on one of these antibiotics, separate it from this powder by at least 2 to 6 hours. Talk with your pharmacist about your specific antibiotic.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Just Relax Watermelon label
Go deeper

The Full Monographs Behind Just Relax Watermelon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Theanine

Interacts with 565 drugs

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...

Read the full Theanine monograph → Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Just Relax Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 135 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
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Magnesium 82 references
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Inositol 14 references
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See these in context on the Inositol monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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