Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Kidney C.O.P. Ingredients & Drug Interactions

by Calcium Oxalate Labs

Kidney C.O.P. label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kidney C.O.P. against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Kidney C.O.P. is a dietary supplement by Calcium Oxalate Labs with 5 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 467 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Magnesium, Vitamin B6, Phytin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Kidney C.O.P. by Calcium Oxalate Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Kidney C.O.P. by Calcium Oxalate Labs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Kidney C.O.P. by Calcium Oxalate Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Kidney C.O.P. contains five active ingredients. Vitamin B6 (pyridoxine) is a B vitamin that plays roles in energy, nerve function, and red blood cell formation.

Magnesium is a mineral involved in muscle and nerve function, energy production, and bone health. Citric acid is a natural compound found in citrus fruits.

Banana is a fruit source of potassium and other nutrients. Phytin (also called IP-6) is a compound found in grains and seeds that may have antioxidant properties.

The product also contains several inactive ingredients — cellulose, magnesium stearate, silicon dioxide, gellan gum, and titanium dioxide — which serve as capsule material and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: inhibit calcium oxalate crystal growth and formation.
  • We looked for evidence on: Kidney stone prevention, Nephrolithiasis, Calcium oxalate calculi.
  • The strongest evidence on file: Vitamin B6 is rated "Possibly Effective" for Kidney stones (nephrolithiasis) (Natural Medicines).
  • Also on file: Magnesium is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis).
  • Also on file: Banana is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis).

Vitamin B6 is Effective for sideroblastic anemia (a blood disorder) and B6 deficiency, and it is Likely Effective for elevated homocysteine (a blood marker linked to heart risk). It is Possibly Effective for pregnancy-related nausea and vomiting.

Magnesium is Effective for indigestion, constipation, and low magnesium levels, and it is Likely Effective for pre-eclampsia (a serious pregnancy condition). Banana is Possibly Effective for diarrhea.

Citric acid and phytin lack sufficient reliable evidence in our data to establish their effectiveness for the conditions listed.

The evidence, ingredient by ingredient Vitamin B6 Citric Acid Magnesium Ip-6 Banana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated at doses under 100 mg daily, though it can cause headache, nausea, heartburn, and loss of appetite in some people. High doses over a long time can harm nerves (sensory neuropathy), especially above 1000 mg daily.

Magnesium is generally well tolerated and commonly causes mild gastrointestinal side effects like diarrhea and nausea. For pregnancy, vitamin B6 is rated Likely Safe and Possibly Unsafe (the data shows mixed safety assessments), and magnesium is rated Likely Safe and Possibly Safe or Unsafe depending on the dose and form.

Banana is safe as a food in pregnancy and while breastfeeding. Phytin carries a safety caution in pregnancy and lactation because supplement safety is not well studied and it can reduce absorption of certain minerals.

Citric acid in food amounts is considered safe in pregnancy and lactation.

Side effects, ingredient by ingredient Vitamin B6 Citric Acid Magnesium Ip-6 Banana

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Ip-6, Vitamin B6, Magnesium, Banana.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 467 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Kidney C.O.P., check with your doctor or pharmacist if you take levodopa or levodopa/carbidopa (Sinemet) for Parkinson's disease — magnesium and banana may both reduce its effectiveness. Also confirm use if you take seizure medications (phenobarbital, phenytoin), blood pressure drugs, heart rhythm medication (amiodarone), muscle relaxants, potassium-sparing water pills, calcium channel blockers, diabetes medications, antibiotics (especially quinolones), bone medications (bisphosphonates), or blood thinners.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Kidney C.O.P. may be worth considering if you have low magnesium, a B6 deficiency, or indigestion — but anyone taking medications for Parkinson's disease, seizures, blood pressure, heart rhythm, muscle relaxation, diabetes, antibiotics, or bone health needs to check their specific drugs with your own doctor or pharmacist before starting, since this product can reduce how well some of those medications work or raise side effects. Talk with your healthcare provider about whether this product fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kidney C.O.P., straight from the product label.

Brand Calcium Oxalate Labs
Barcode (UPC) 860224000404
Net contents 120 Delayed Release Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 251046
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kidney C.O.P. by Calcium Oxalate Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Delayed Release Vegetarian Capsule(s)
Maximum serving Sizes:
2 Delayed Release Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
860224000404
IngredientAmount% DV
Vitamin B65 mg294%
Citric Acid350 mg--
Magnesium45 mg11%
Phytin200 mg--
Banana200 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide, Gellan Gum, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Kidney C.O.P. was specifically formulated to help inhibit the rate of growth and formation of calcium oxalate crystals. This new, patented and revolutionary formula contains select ingredients sourced from around the world that are demonstrated to affect calcium oxalate crystal formation. Optimized and patented five ingredient formula Manufactured in a FDA registered cGMP facility Encapsulated in USA with select FDA G.R.A.S. ingredients

Free of any preservatives, artificial colors, flavors, sweeteners, sugars, soy, gluten, wheat, yeast, fish and sodium.

In vitro tests show that patented formula inhibits rate of calcium oxalate crystal growth by 99%.

Patented formula 99% inhibition of calcium oxalate crystals Ingredients clinically shown to inhibit calcium oxalate crystals Supports proper kidney function and health

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Product patents: US 9,233,135 | US 9,492,491 | US 9,623,066 I US 9,789,152 I US 10,471,115

Seals/Symbols

Manufactured at an FDA registered facility

GRAS Generally Recognized As Safe

Encapsulated in USA

GMP quality Good Manufacturing Practice certification

Precautions

Important: Tamper resistant outer seal around cap and pressure seal under cap. Do not use if either seal is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Store at room temperature, tightly closed.

General Statements

Expiration date: See bottom of bottle

30 day supply

Formula

Calcium Oxalate Protector

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take two (2) capsules twice daily (am and pm) preferably with meals. For best results, it is recommended to consume at least six 8-ounce glasses of water daily with lemon juice, decrease caffeine intake, eliminate colas, decrease oxalate-rich foods such as spinach, strawberries, nuts, and tea, decrease sodium, sugar, and red meat consumption and increase fiber intake.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kidney C.O.P. by Calcium Oxalate Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kidney C.O.P. label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kidney C.O.P. by Calcium Oxalate Labs

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Delayed Release Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
5 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Citric Acid

No known
interactions
350 mg per serving

Citric acid is a natural acid found in citrus fruits and is widely used as a safe food additive, flavoring, and preservative. In medicine, citrate for...

Citric Acid monograph & interactions

Magnesium

Interacts with
295 drugs
45 mg per serving Form: Magnesium Citrate

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Phytin

Interacts with
122 drugs
200 mg per serving Form: Inositol Hexakisphosphate

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, ofte...

Phytin monograph & interactions

Banana

Interacts with
5 drugs
200 mg per serving

Bananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While s...

Banana monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide, Gellan Gum, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kidney C.O.P. by Calcium Oxalate Labs Drug Interactions

Want to check YOUR meds against Kidney C.O.P.?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
467Drugs
6 Major 459 Moderate 2 Minor

Ingredients driving the most interactions

Magnesium 295
Vitamin B6 210
Phytin 122
Banana 5

Individual Drug Interactions

The ingredients in Kidney C.O.P. interact with 467 drugs. Click any drug to see the details.

4 of the 5 ingredients in Kidney C.O.P. interact with drugs. Each result below shows which ingredient is responsible. Magnesium Vitamin B6 Phytin Banana

Each ingredient & the kinds of drugs it affects

For each ingredient in Kidney C.O.P. with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnesium15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B
Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D
Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B
Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D
Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B
Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D
Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D
Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A
Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B
Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B
Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B
Magnesium full monograph & interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Phytin1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of IP-6 with drugs that affect platelet aggregation may increase the risk of bleeding. In vitro IP-6 can inhibit platelet aggregation. This effect has not been demonstrated in humans.

Likelihood Unlikely Evidence D
Phytin full monograph & interactions

Banana1 drug type · 5 drugs

Levodopa

Taking banana may reduce the effectiveness of levodopa.
A case report describes apparent wearing off in a patient with Parkinson disease after eating a banana every day. The wearing off subsided after removing dietary bananas.

Likelihood Possible Evidence D
Banana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kidney C.O.P., from the product label.

Calcium Oxalate Labs

See all Calcium Oxalate Labs products
Name
Calcium Oxalate Labs, Inc.
City
Fort Lauderdale
State
FL
ZipCode
33312
Phone Number
1-800-586-9424
Pharmacist Counseling Corner

Kidney C.O.P. by Calcium Oxalate Labs: Common Questions

Does Kidney C.O.P. by Calcium Oxalate Labs interact with any medications?
Yes. Based on its ingredients, Kidney C.O.P. has a known interaction with 467 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kidney C.O.P. contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is vitamin B6 in this product safe to take every day?
Vitamin B6 is well tolerated at doses under 100 mg daily. This product doesn't state its B6 dose on the facts provided, so check the label and confirm with your pharmacist that the daily amount is safe for long-term use.
Can I take this while pregnant?
Magnesium is rated Likely Safe in pregnancy and is actually needed — but use supplements only under your doctor's guidance. Vitamin B6 has mixed safety data in pregnancy (Likely Safe and Possibly Unsafe ratings exist). Banana as a food is safe. Talk with your doctor before starting any supplement in pregnancy.
Will this product help with kidney stones?
Citric acid is listed for kidney stones on the label, but our data shows insufficient reliable evidence to establish whether it works for that condition. Your doctor can advise whether citric acid supplementation is right for your situation.
What are the most common side effects?
Vitamin B6 may cause headache, nausea, or heartburn. Magnesium commonly causes diarrhea, nausea, and stomach upset. Banana may cause bloating, gas, or cramping. Most people tolerate these ingredients without trouble at normal doses.
Does this product contain fillers?
Yes. Besides the five active ingredients, the capsules contain cellulose, magnesium stearate, silicon dioxide, gellan gum, and titanium dioxide — these are inactive ingredients that help form and stabilize the capsule.
Is phytin safe as a supplement?
Phytin (IP-6) from food sources is generally considered low-risk, but supplement safety is not well studied. We advise against supplemental phytin in pregnancy and while breastfeeding due to insufficient safety data. Check with your doctor before taking it as a supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kidney C.O.P. label
Go deeper

The Full Monographs Behind Kidney C.O.P.’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Citric Acid

Citric acid is a natural acid found in citrus fruits and is widely used as a safe food additive, flavoring, and preservative. In medicine, citrate forms (like potassium or sodium citrate) ar...

Read the full Citric Acid monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Ip-6

Interacts with 122 drugs

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, often paired with inositol. It is most studi...

Read the full Ip-6 monograph → Herb & supplement monograph

Banana

Interacts with 5 drugs

Bananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While some traditional uses (like easing diarrh...

Read the full Banana monograph →
Sources

Sources & How We Checked

Kidney C.O.P.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 138 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
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Citric Acid 10 references
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Ip-6 3 references
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Banana 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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