Kyo-Dophilus Ingredients & Drug Interactions
by Kyo-Dophilus
What is this page for?
First and foremost: checking Kyo-Dophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Kyo-Dophilus is a dietary supplement by Kyo-Dophilus with 3 active ingredients. Its ingredients are commonly taken for digestive health and regularity, diarrhea (including antibiotic-related), irritable bowel syndrome (ibs) symptoms.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium bifidum, Bifidobacterium longum, Lactobacillus gasseri. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Kyo-Dophilus by Kyo-Dophilus
Ask about any prescription or over-the-counter medication and we check it for interactions with Kyo-Dophilus by Kyo-Dophilus — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Kyo-Dophilus by Kyo-Dophilus
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Kyo-Dophilus has three active probiotic ingredients: Bifidobacterium bifidum, Bifidobacterium longum, and Lactobacillus gasseri. These are live beneficial bacteria meant to support your gut health.
The capsule also contains inactive ingredients—gelatin, potato starch, and silica—that help hold the product together.
Does it work?
Moderate evidence
The evidence for these three strains is mixed. Bifidobacterium bifidum is possibly effective for irritable bowel syndrome (IBS) and respiratory tract infections, but for other conditions the evidence is too thin to say.
Bifidobacterium longum and Lactobacillus gasseri have insufficient reliable evidence for the conditions studied so far—we don't have enough data to know whether they work. That doesn't mean they won't help you; it means larger or better studies are needed.
How safe is it?
Well-documented data
These probiotics are generally well tolerated in healthy people. That said, if you have a weakened immune system or are seriously ill, be cautious and check with your doctor first.
Bloating and flatulence have been reported with probiotics in general, though rarely with these specific strains. Rare cases of bacterial blood infection (bacteremia) have occurred in critically ill patients, especially newborns, but these are uncommon.
Bifidobacterium longum is rated possibly safe in pregnancy and lactation, but the other two don't have enough safety data—talk to your doctor if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
The main thing to watch for: antibiotic drugs. Because these are live bacteria, antibiotics taken at the same time can reduce how well the probiotic works.
Separate your doses by a few hours, and let your pharmacist know you're taking this product alongside any antibiotics.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Kyo-Dophilus is a straightforward three-strain probiotic that may help with IBS and respiratory infections, though evidence is limited for many other uses. If you take antibiotics, space out the doses so they don't cancel each other out.
If you have a weakened immune system or are seriously ill, check with your doctor before starting. Talk to your pharmacist about timing if you're on any medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Kyo-Dophilus, straight from the product label.
| Brand | Kyo-Dophilus |
|---|---|
| Barcode (UPC) | 023542600491 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2015 |
| DSLD ID | 42072 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Children (All), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Kyo-Dophilus by Kyo-Dophilus, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium bifidum | 0 NP | -- |
| Bifidobacterium longum | 0 NP | -- |
| Lactobacillus gasseri | 0 NP | -- |
| Proprietary Blend (Non-Nutrient/Non-Botanical) | 0 NP | -- |
Other ingredients: Gelatin, Potato Starch, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General
L600A49N
Brand IP Statement(s)
KYO-DOPHILUS(R) is formulated with three specially cultured, non-dairy, heat-stable, stomach acid resistant, human strains of beneficial bacteria. This Friendly Trio(TM) gives you relief from the inconvenience caused by bad bacteria.
General Statements
Take Kyo-Dophilus during and after a cycle of medication, when you travel, and everyday to boost immunity, promote healthy intestinal function and general well-being.
Guaranteed stable at time of consumption.
Promotes Healthy Intestinal Function
Digestion and Immune Health
Restore Balance Protect
Formulation
Dairy free.
FREE OF: preservatives, sugar, sodium, dairy, yeast, gluten, artificial colors and flavors.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
TAMPER RESISTANT CAP AND SEAL: Do not use if cap drop ring or printed inner seal is broken or missing.
Keep out of reach of children.
Seals/Symbols
GMP Certified
FDA Statement of Identity
PROBIOTIC SUPPLEMENT
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Take one capsule for adults (1/2 capsule for children under four) with a meal twice daily. For infants, sprinkle 1/2 capsule in food or juice.
Storage
Store in a cool, dry place with cap tight. Refrigeration not required.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Kyo-Dophilus by Kyo-Dophilus label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Kyo-Dophilus by Kyo-Dophilus
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend (Non-Nutrient/Non-Botanical)
Other (inactive) ingredients: Gelatin, Potato Starch, Silica. These complete the product’s ingredient list but are not active constituents.
Kyo-Dophilus by Kyo-Dophilus Drug Interactions
HelloPharmacist Interaction Report
Kyo-Dophilus contains three probiotic bacteria strains, and they all interact with the same medication type.
The most serious concern is with antibiotic drugs: because these probiotics are made of live organisms, taking antibiotics at the same time can kill off a significant portion of the beneficial bacteria, making the supplement less effective. The interaction is rated Moderate.
Read the full breakdown — every affected drug type, severity by severity
All three ingredients—Bifidobacterium bifidum, Bifidobacterium longum, and Lactobacillus gasseri—carry this same antibiotic interaction. The solution is straightforward: separate when you take them.
Your pharmacist or doctor can help you space out doses so the antibiotic and the probiotic aren't working against each other.
Always check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Kyo-Dophilus?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Kyo-Dophilus interact with 182 drugs. Click any drug to see the details.
3 of the 3 ingredients in Kyo-Dophilus interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium bifidum Bifidobacterium longum Lactobacillus gasseri
Lefamulin AcetateXenleta
How Lefamulin Acetate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Lefamulin Acetate interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Lefamulin Acetate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Lefamulin Acetate interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Levofloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Levofloxacin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Levofloxacin (ophthalmic) interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Levofloxacin (ophthalmic) interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Levofloxacin (ophthalmic) interactionLincomycin HclLincocin, Lincorex
How Lincomycin Hcl interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Lincomycin Hcl interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Lincomycin Hcl interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Lincomycin Hcl interactionLinezolidZyvox, Zyvox Injection
How Linezolid interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Linezolid interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Linezolid interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Linezolid interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Lomefloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Lomefloxacin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Lomefloxacin interactionLoracarbefLorabid
How Loracarbef interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Loracarbef interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Loracarbef interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Loracarbef interactionMeropenemMerrem IV
How Meropenem interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Meropenem interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Meropenem interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Meropenem interactionMeropenem, VaborbactamVabomere
How Meropenem, Vaborbactam interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Lactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Meropenem, Vaborbactam interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Meropenem, Vaborbactam interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Meropenem, Vaborbactam interactionMethacyclineRondomycin
How Methacycline interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methacycline interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methacycline interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methacycline interactionMethenamine HippurateHiprex, Urex
How Methenamine Hippurate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine Hippurate interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine Hippurate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine Hippurate interactionMethenamine MandelateMandelamine, Methimazole
How Methenamine Mandelate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine Mandelate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine Mandelate interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine Mandelate interactionMethenamine Mandelate, Potassium Acid PhosphateThiacide
How Methenamine Mandelate, Potassium Acid Phosphate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine Mandelate, Potassium Acid Phosphate interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine Mandelate, Potassium Acid Phosphate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine Mandelate, Potassium Acid Phosphate interactionMethenamine Mandelate, Sodium Acid PhosphateUroquid-Acid No. 2
How Methenamine Mandelate, Sodium Acid Phosphate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine Mandelate, Sodium Acid Phosphate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine Mandelate, Sodium Acid Phosphate interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine Mandelate, Sodium Acid Phosphate interactionMethenamine, Phenyl Salicylate, Methylene BlueProsed DS
How Methenamine, Phenyl Salicylate, Methylene Blue interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine, Phenyl Salicylate, Methylene Blue interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine, Phenyl Salicylate, Methylene Blue interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine, Phenyl Salicylate, Methylene Blue interactionMethenamine, Sodium BiphosphateUro-Phosphate
How Methenamine, Sodium Biphosphate interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Methenamine, Sodium Biphosphate interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Methenamine, Sodium Biphosphate interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Methenamine, Sodium Biphosphate interactionMetronidazoleAnabact, Flagyl, Flagyl IV, Flagyl IV RTU, Likmez, Metro IV +12 more
How Metronidazole interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Metronidazole interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Metronidazole interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Metronidazole interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMezlocillinMezlin
How Mezlocillin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Mezlocillin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Mezlocillin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Mezlocillin interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Minocycline interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Minocycline interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Minocycline Hydrochloride interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Minocycline Hydrochloride interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Minocycline Hydrochloride interactionMoxifloxacinAvelox
How Moxifloxacin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Moxifloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Moxifloxacin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Moxifloxacin interactionNafcillinNallpen
How Nafcillin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Nafcillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Nafcillin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Nafcillin interactionNafcillin SodiumUnipen
How Nafcillin Sodium interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Nafcillin Sodium interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Nafcillin Sodium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Nafcillin Sodium interactionNalidixic AcidNegGram
How Nalidixic Acid interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Nalidixic Acid interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Nalidixic Acid interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Nalidixic Acid interactionNeomycinMycifradin, Myciguent, Neo-Fradin
How Neomycin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Neomycin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Neomycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Neomycin interactionNetilmicinNetromycin
How Netilmicin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Netilmicin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Netilmicin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Netilmicin interactionNitrofurantoinFuradantin, Furatoin, Macrobid, Macrodantin
How Nitrofurantoin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Nitrofurantoin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Nitrofurantoin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Nitrofurantoin interactionNorfloxacinNorflox, Noroxin
How Norfloxacin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Norfloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Norfloxacin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Norfloxacin interactionOfloxacinFloxin, Floxin Injection, Floxin Otic, Oflox
How Ofloxacin interacts with Kyo-Dophilus — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ofloxacin interactionLactobacillus GasseriAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Gasseri + Ofloxacin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ofloxacin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Kyo-Dophilus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium bifidum
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
Bifidobacterium longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Lactobacillus gasseri
Antibiotic Drugs
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.
Brand information
Manufacturer and brand details for Kyo-Dophilus, from the product label.
Kyo-Dophilus
See all Kyo-Dophilus products- Name
- Wakunaga of America Co., Ltd.
- Street Address
- 23501 Madero
- City
- Mission Viejo
- State
- CA
- ZipCode
- 92691
- Web Address
- www.kyolic.com
Kyo-Dophilus by Kyo-Dophilus: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Kyo-Dophilus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Kyo-Dophilus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographBifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographLactobacillus Gasseri
Interacts with 182 drugsLactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...
Read the full Lactobacillus Gasseri monograph →Sources & How We Checked
Kyo-Dophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Lactobacillus Gasseri 12 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
- Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
- Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
- Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
- Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
- Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
- Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
- Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
- Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed
See these in context on the Lactobacillus Gasseri monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC