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Dietary supplement

Liferoot Ingredients & Drug Interactions

by Red Moon Herbs

Liferoot label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Liferoot against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Liferoot is a dietary supplement by Red Moon Herbs with 1 active ingredient. Its ingredients are commonly taken for menstrual complaints, easing childbirth (traditional), urinary discomfort.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Life Root Flowering Top Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Liferoot by Red Moon Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Liferoot by Red Moon Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Liferoot by Red Moon Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Liferoot contains one active ingredient: life root flowering top extract, derived from golden ragwort. The product also includes water and alcohol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Golden Ragwort product and its label doesn't state a use — see Golden Ragwort's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for this product in our records.

The evidence, ingredient by ingredient Golden Ragwort

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Golden ragwort carries serious safety concerns. It contains pyrrolizidine alkaloids — plant toxins that can damage your liver and lungs.

With regular use, these alkaloids build up and can cause veno-occlusive disease (a condition where liver blood vessels become scarred), leading to belly pain, vomiting, diarrhea, fluid buildup, and an enlarged liver within weeks. The product can also harm your lungs and raise blood pressure in the lung arteries.

The safety data advises against use during pregnancy or while breastfeeding; the toxic alkaloids can harm a developing baby or pass to an infant through breast milk.

Side effects, ingredient by ingredient Golden Ragwort

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Golden Ragwort.
  • The most serious interaction on file is rated Moderate.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take CYP3A4 inducers (drugs that speed up a liver pathway) — which include certain seizure medications and others — check with your pharmacist before starting this product; it may increase your risk of toxicity from the plant's harmful alkaloids.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product carries serious liver and lung toxicity risks from its pyrrolizidine alkaloid content. It is not recommended for routine use, particularly not during pregnancy or breastfeeding.

Talk with your pharmacist before considering it — they can help you weigh any potential benefit against these documented harms.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liferoot, straight from the product label.

Brand Red Moon Herbs
Barcode (UPC) 857999002306
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 319293
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Children (All), Infants/Baby (0 - 1 Year), Seniors/Mature (>50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liferoot by Red Moon Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
857999002306
IngredientAmount% DV
Life Root Flowering Top Extract0 NP--

Other ingredients: Water, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake well. Take 10-30 drops 1-3 times daily in a little water.

Precautions

Consults expert medical advice before using while pregnant or nursing.

Other contraindications may exist.

General Statements

Red Moon Herbs Est. 1994 Still made the wise woman way

FDA Statement of Identity

Dietary Supplement

Formula

Fresh Appalachian extracts for the whole family

Formulation

Fresh Appalachian extracts for the whole family

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Liferoot by Red Moon Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Liferoot label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Liferoot by Red Moon Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Amounts shown are per serving.

Life Root Flowering Top Extract

Interacts with
87 drugs
0 NP per serving Form: Senecio aureus Flowering Top Extract

Golden Ragwort is a flowering plant once used in traditional and folk medicine, mainly for menstrual and female reproductive complaints. It contains p...

Life Root Flowering Top Extract monograph & interactions

Other (inactive) ingredients: Water, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liferoot by Red Moon Herbs Drug Interactions

Want to check YOUR meds against Liferoot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

Life Root Flowering Top Extract 87

Individual Drug Interactions

The ingredients in Liferoot interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in Liferoot interact with drugs. Each result below shows which ingredient is responsible. Life Root Flowering Top Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Liferoot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Life Root Flowering Top Extract1 drug type · 87 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in golden ragwort.
Golden ragwort contains PAs. PAs are substrates of CYP3A4. Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites.

Likelihood Possible Evidence D
Life Root Flowering Top Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Liferoot, from the product label.

Red Moon Herbs

See all Red Moon Herbs products
Name
Red Moon Herbs
City
Asheville
State
NC
Phone Number
888-929-0777
Web Address
redmoonherbs.com
Pharmacist Counseling Corner

Liferoot by Red Moon Herbs: Common Questions

Does Liferoot by Red Moon Herbs interact with any medications?
Yes. Based on its ingredients, Liferoot has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liferoot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Liferoot while I'm pregnant?
The safety data advises against it. The product contains toxic alkaloids that can harm a developing baby. Talk with your doctor or pharmacist about your specific situation.
Can I take Liferoot while breastfeeding?
The safety data advises against it. The toxic alkaloids can pass into breast milk and harm your infant. Discuss this with your doctor or pharmacist before use.
What are pyrrolizidine alkaloids and why are they a problem?
Pyrrolizidine alkaloids are plant toxins found in golden ragwort. They can build up in your body and damage your liver, causing veno-occlusive disease (scarring of liver blood vessels), and can also harm your lungs. This is the main safety concern with this product.
What is veno-occlusive disease and how fast does it develop?
It's a condition where liver blood vessels become scarred and blocked. Early signs — belly pain, vomiting, diarrhea, and fluid buildup — can appear within days of exposure; a persistently enlarged liver shows up within a few weeks of ongoing use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liferoot label
Go deeper

The Full Monographs Behind Liferoot’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Golden Ragwort

Interacts with 87 drugs

Golden Ragwort is a flowering plant once used in traditional and folk medicine, mainly for menstrual and female reproductive complaints. It contains pyrrolizidine alkaloids that can cause se...

Read the full Golden Ragwort monograph →
Sources

Sources & How We Checked

Liferoot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Golden Ragwort 4 references
  1. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  2. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  3. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  4. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed

See these in context on the Golden Ragwort monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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