Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Lipolean Ingredients & Drug Interactions

by NutraBio

Lipolean label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lipolean against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lipolean is a dietary supplement by NutraBio with 6 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 2,056 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glucomannan, Inositol, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lipolean by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with Lipolean by NutraBio — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lipolean by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Lipolean contains 6 active ingredients. Inositol is a naturally occurring compound studied for blood sugar control and reproductive health.

L-carnitine helps your body produce energy and has been studied for heart and cholesterol support. Choline bitartrate supports cell function and is especially important during pregnancy and lactation.

DL-methionine is an amino acid your body uses for various protein functions. Glucomannan is a soluble fiber from the konjac plant that absorbs water in your digestive tract.

LipoSan Ultra Chitosan is a fiber derived from shellfish shells, studied for weight management and heart health. The capsule itself is made from gelatin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Fat inhibitor and weight management support.
  • We looked for evidence on: Dyslipidemia, Hypercholesterolemia, Hyperlipidemia, Hypertriglyceridemia, Obesity, Metabolic health — and 1 related terms.
  • The strongest evidence on file: Glucomannan is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Chitosan is rated "Possibly Effective" for Obesity.
  • Also on file: L-carnitine is rated "Possibly Effective" for Hyperlipidemia.

Inositol is possibly effective for polycystic ovary syndrome (PCOS), metabolic syndrome, and preterm labor, though the evidence for anxiety, diabetic nerve pain, and depression is not strong. L-carnitine is effective for L-carnitine deficiency and possibly effective for high cholesterol, heart failure, and angina.

Choline has insufficient evidence in our data for athletic performance, age-related cognitive decline, and several other uses. Glucomannan is possibly effective for constipation, diabetes, and high cholesterol.

Chitosan is possibly effective for obesity, recovery after surgery, and blood pressure, though evidence for Crohn disease and dry eye is insufficient. We hold no effectiveness ratings for DL-methionine.

The evidence, ingredient by ingredient Inositol L-carnitine Choline Glucomannan Chitosan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated, though it can cause diarrhea, gas, and nausea at common doses. Safety in pregnancy isn't fully established — use only under medical supervision if you're pregnant.

L-carnitine is generally well tolerated at typical doses but can cause stomach upset and a fishy body odor at high doses; safety data in pregnancy and while breastfeeding are limited. Choline is rated likely safe in pregnancy when used as advised by your doctor, and your needs are actually higher while breastfeeding — but use supplements only under professional guidance.

High doses of choline (over 3.5 grams daily) can cause the same fishy odor, plus nausea, vomiting, and diarrhea. Glucomannan is generally well tolerated with plenty of water but can rarely cause choking or blockage if swallowed improperly; safety data in pregnancy and while breastfeeding are not sufficient to recommend it.

Chitosan is generally well tolerated short-term but should be avoided in pregnancy and while breastfeeding due to insufficient safety data — also watch for shellfish allergy since it's derived from shellfish.

Side effects, ingredient by ingredient Inositol L-carnitine Choline Glucomannan Chitosan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Glucomannan, Inositol, Choline, Chitosan, L-carnitine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 2,057 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take any diabetes medications, blood thinners (warfarin or acenocoumarol), thyroid hormone replacement, the antiviral acyclovir, or atropine. Because glucomannan can reduce absorption of oral drugs in general, it's important to verify your specific medications — a small study showed it reduced levels of an oral diabetes drug, so spacing doses may be needed.

If you're on any prescription medication, verify it against the interaction tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lipolean may be worth considering if you're interested in weight management, cholesterol support, or blood sugar control and have checked your medications against the interaction tool. Be especially cautious if you take diabetes drugs, blood thinners, thyroid hormones, or antivirals.

Pregnant women and those breastfeeding should talk with their doctor or pharmacist before starting — several ingredients have safety gaps in pregnancy and lactation. Run your full medication list through the checker below before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lipolean, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908210908
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50914
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lipolean by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
60
UPC/BARCODE
649908210908
IngredientAmount% DV
Inositol37.5 mg--
L-Carnitine37.5 mg--
Choline Bitartrate37.5 mg--
DL-Methionine37.5 mg--
Glucomannan150 mg--
LipoSan Ultra Chitosan1500 mg--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Fat Inhibitor & Eliminator. Lab Tested for Potency.

60 Servings

Made in a GMP & FDA Inspected Facility

Manufactured in a GMP & FDA inspected facility

WEIGHT LOSS

Formulation

Free of Harmful Impurities.

- No fillers - No excipients - No additives

Non-GMO Gluten free BSE/TSE free

Seals/Symbols

TRUE LABEL FULL LABEL DISCLOSURE

LipoSan Ultra LipoSan ULTRA is a registered trademark of Primex ehf.

NutraBio since 1996

{Flag} Made in the USA

FDA Statement of Identity

Dietary Supplement

Precautions

Allergens: Contains shellfish.

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

Formula

Allergens: Contains shellfish.

With Liposan Ultra Chitosan

Storage

STORE IN A COOL DRY PLACE.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

General

21090-006 B20088-002

Suggested/Recommended/Usage/Directions

3 capsules daily with meals Suggested Use: As a dietary supplement, take 3 capsules with meals or as directed by a physician. Refrain from taking 3 hours before or after ingestion of fat soluble vitamins (A,D,E,K) or medications.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lipolean by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lipolean label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lipolean by NutraBio

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Inositol

Interacts with
86 drugs
37.5 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

L-Carnitine

Interacts with
19 drugs
37.5 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine monograph & interactions

Choline Bitartrate

Interacts with
16 drugs
37.5 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline Bitartrate monograph & interactions

DL-Methionine

37.5 mg per serving

Glucomannan

Interacts with
2,022 drugs
150 mg per serving

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and mo...

Glucomannan monograph & interactions

LipoSan Ultra Chitosan

Interacts with
3 drugs
1500 mg per serving Form: Shellfish

Chitosan is a fiber-like substance made from the shells of shrimp, crabs, and other shellfish, often marketed for weight loss and cholesterol. The evi...

LipoSan Ultra Chitosan monograph & interactions

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lipolean by NutraBio Drug Interactions

Want to check YOUR meds against Lipolean?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,056Drugs
2,052 Moderate 4 Minor

Ingredients driving the most interactions

Glucomannan 2,022
Inositol 86
L-Carnitine 19
Choline Bitartrate 16
LipoSan Ultra Chitosan 3

Individual Drug Interactions

The ingredients in Lipolean interact with 2,056 drugs. Click any drug to see the details.

5 of the 6 ingredients in Lipolean interact with drugs. Each result below shows which ingredient is responsible. Glucomannan Inositol L-Carnitine Choline Bitartrate LipoSan Ultra Chitosan

Each ingredient & the kinds of drugs it affects

For each ingredient in Lipolean with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Glucomannan1 drug type · 2,022 drugs

Oral Drugs

Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.

Likelihood Probable Evidence B
Glucomannan full monograph & interactions

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions

Choline Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline Bitartrate full monograph & interactions

LipoSan Ultra Chitosan2 drug types · 3 drugs

Acyclovir (Zovirax)

Chitosan can reduce the absorption of acyclovir, potentially increasing the risk for treatment failure.
Clinical research in humans shows that taking chitosan along with acyclovir 200 mg reduces acyclovir absorption. Concomitant administration of chitosan 400 mg or 1000 mg reduced the acyclovir area under the curve (AUC) and peak plasma concentration by about 30% and 40%, respectively, compared with control. Concomitant administration with chitosan 1000 mg also increased time to peak concentration from 1 hour to 2 hours. In vitro research suggests that the mechanism for reduced absorption is due to acyclovir entrapment in chitosan-mucus complexes, which reduces intestinal absorption.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Theoretically, chitosan might increase the risk of bleeding when taken with warfarin.
In a case report, a patient taking warfarin had a significantly increased international normalized ratio (INR) after starting chitosan 1200 mg daily. The INR normalized after chitosan was discontinued and vitamin K was administered. The patient once again started taking chitosan and again had a significant increase in INR. The INR stabilized again once chitosan was discontinued. Researchers theorize that this interaction might occur because chitosan decreases absorption of fat-soluble vitamins, including vitamin K, which could increase the anticoagulant effect of warfarin.

Likelihood Possible Evidence D
LipoSan Ultra Chitosan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lipolean, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

Lipolean by NutraBio: Common Questions

Does Lipolean by NutraBio interact with any medications?
Yes. Based on its ingredients, Lipolean has a known interaction with 2,056 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lipolean contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Lipolean safe to take if I'm pregnant or breastfeeding?
Safety varies by ingredient. Choline is rated likely safe in pregnancy and is actually important during lactation, but only use prenatal or supplement doses as your doctor advises. Inositol has been studied in pregnancy but should only be used under medical supervision. Glucomannan and chitosan don't have enough safety data in pregnancy or while breastfeeding — avoid them unless your doctor says otherwise. Talk with your pharmacist or doctor about which ingredients are right for you.
What side effects might I notice?
The most common are digestive — gas, bloating, diarrhea, nausea, and constipation, depending on the ingredient. Some people report a fishy body odor from choline or L-carnitine, especially at higher doses. These tend to be mild, but if you experience severe stomach pain or have trouble swallowing, stop and contact your pharmacist or doctor right away.
Can Lipolean help me lose weight?
Chitosan and glucomannan are both studied for weight management and are rated possibly effective, so there's some evidence. Inositol and L-carnitine may support metabolic health, though that's different from weight loss directly. Results vary, and no supplement replaces diet and exercise — ask your doctor if Lipolean fits your overall plan.
Will this interfere with my diabetes medication?
Inositol can increase the risk of low blood sugar when combined with diabetes drugs, and glucomannan may reduce how well your body absorbs oral diabetes medication like glyburide. If you take any diabetes drug, check it against the interaction tool before starting Lipolean, and let your doctor know you're adding it so they can monitor your blood sugar.
Does Lipolean contain any common allergens?
Chitosan is derived from shellfish shells, so if you have a shellfish allergy, this product is not for you. The gelatin capsule is also derived from animal sources. Check the label for any other allergen warnings specific to your batch.
Why do I need to take this with plenty of water?
Glucomannan is a soluble fiber that swells when it absorbs water — it's actually designed to do that in your digestive tract. Without enough liquid, it can form a blockage in your throat or esophagus, which is rare but serious. Always take it with a full glass of water and make sure you swallow it properly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lipolean is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lipolean label
Go deeper

The Full Monographs Behind Lipolean’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph → Herb & supplement monograph

Glucomannan

Interacts with 2,022 drugs

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...

Read the full Glucomannan monograph → Herb & supplement monograph

Chitosan

Interacts with 3 drugs

Chitosan is a fiber-like substance made from the shells of shrimp, crabs, and other shellfish, often marketed for weight loss and cholesterol. The evidence for these benefits is weak, and an...

Read the full Chitosan monograph →
Sources

Sources & How We Checked

Lipolean's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 101 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

L-carnitine 41 references
  1. Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
  2. Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
  3. Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
  4. Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
  5. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  6. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  7. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  8. Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
  9. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  10. Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
  11. Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
  12. Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
  13. Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
  14. Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
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Choline 14 references
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Glucomannan 15 references
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Chitosan 17 references
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See these in context on the Chitosan monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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