Interactions on record — worth a quick check against your medications. Based on 9 of 11 ingredients. Check your meds →
Dietary supplement

Liver Chol Ingredients & Drug Interactions

by Sunshine Naturals

Liver Chol label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Liver Chol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Liver Chol is a dietary supplement by Sunshine Naturals with 11 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 445 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vit. B6, Niacinamide, Inositol Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Liver Chol by Sunshine Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Liver Chol by Sunshine Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Liver Chol by Sunshine Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Liver Chol contains 11 ingredients, most of them B vitamins and amino acids that support liver health. The active ingredients include vitamin B12, pantothenic acid, choline bitartrate, methionine, niacinamide, vitamin B2, vitamin B1, liver concentrate, inositol complex, vitamin B6, and desiccated liver.

There are no other inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Sideroblastic anemia — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Imerslund-Grasbeck disease — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Pantothenic acid deficiency — rated "Effective" (Pantothenic Acid) (Natural Medicines).
  • On file: Vitamin B12 deficiency — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Vitamin B6 deficiency — rated "Effective" (Vitamin B6) (Natural Medicines).

The evidence for this product varies by ingredient. Vitamin B12 is effective for B12 deficiency and likely effective for cyanide poisoning; it's possibly effective for canker sores and a nerve-pain condition called postherpetic neuralgia.

Niacinamide is likely effective for pellagra and possibly effective for acne, high phosphate in blood, osteoarthritis, and diabetes. Vitamin B6 is effective for a type of anemia and B6 deficiency, likely effective for high homocysteine, and possibly effective for pregnancy-related nausea.

Inositol is possibly effective for polycystic ovary syndrome and metabolic syndrome. For most other uses listed in the research, the evidence is either insufficient to rate or shows the ingredient is possibly ineffective—we don't have effectiveness data established for vitamin B2, choline, methionine, liver extract, or pantothenic acid for the conditions listed.

The evidence, ingredient by ingredient Vitamin B12 Pantothenic Acid Choline Methionine Niacinamide Riboflavin Liver Extract Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 9 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated at normal doses. Vitamin B12, pantothenic acid, niacinamide, and vitamin B2 are considered likely safe in pregnancy and lactation at recommended amounts.

Choline and inositol are likely safe in pregnancy but should be used only under a doctor's guidance at supplement doses. Methionine and liver extract carry more caution in pregnancy — methionine supplement doses haven't been proven safe during pregnancy, and liver extract can carry very high vitamin A, which may harm a developing baby.

Vitamin B6 is usually safe in pregnancy at recommended amounts but is listed as possibly unsafe at high doses. The most common side effects are mild: nausea, diarrhea, and stomach upset with several ingredients; vitamin B2 can turn urine bright yellow.

Rare serious effects include nerve damage (sensory neuropathy) from very high doses of vitamin B6 over time, and a very rare severe low potassium (hypokalemia) with B12 when it corrects certain types of anemia. Liver extract carries theoretical concern about contamination from animal sources, though no cases have been reported in humans.

Side effects, ingredient by ingredient Vitamin B12 Pantothenic Acid Choline Methionine Niacinamide Riboflavin Liver Extract Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 9 matched ingredients can interact with medications — Inositol, Choline, Vitamin B12, Vitamin B6, Riboflavin, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; Parkinson's medications.
  • For scale: 445 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Liver Chol, check with your doctor or pharmacist if you take blood thinners like warfarin (niacinamide and liver extract may affect them — Moderate and Minor severity), antihypertensive drugs (vitamin B6 — Moderate), seizure medications like phenytoin, phenobarbital, or carbamazepine (vitamin B6 and niacinamide — Moderate), antidiabetes drugs (inositol may lower blood sugar — Moderate), metformin (vitamin B12 can be depleted by it — Minor), amiodarone for heart rhythm (vitamin B6 — Moderate), atropine (choline — Minor), iron supplements or medications (liver extract — Minor), or levodopa for Parkinson's disease (vitamin B6, though not if you also take carbidopa — Minor). No interactions are documented for the vitamin B1 in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Liver Chol is a B-vitamin and amino-acid supplement aimed at supporting liver function, with some ingredients backed by decent evidence for specific uses like B12 deficiency or B6 for pregnancy nausea. It's generally well tolerated, but it does interact with blood thinners, some blood-pressure and seizure medications, and can add to your iron intake if you're already supplementing.

If you take warfarin, any seizure medication, blood-pressure drugs, metformin, or iron supplements, talk with your own doctor or pharmacist before starting this product to make sure it's safe for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 10 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liver Chol, straight from the product label.

Brand Sunshine Naturals
Barcode (UPC) 789939100875
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 271292
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liver Chol by Sunshine Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
789939100875
IngredientAmount% DV
Vitamin B122 mcg33%
Pantothenic Acid2 mg20%
Choline Bitartrate240 mg--
Methionine110 mg--
Niacinamide10 mg50%
Vitamin B23 mg176%
Vitamin B13 mg200%
Liver concentrate30 mg--
Inositol Complex83 mg--
Vit. B62 mg100%
dessicated Liver56 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily.

Storage

Important: Store tightly closed in a dry place at controlled room temperature of 59 degrees - 86 degrees F (15 degrees - 30 degrees C).

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Metischol is a registered trademark of Propharma Inc.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

FDA Statement of Identity

Dietary Supplement

General Statements

Compare to Metischol

Seals/Symbols

Proudly Made in the USA.

Formulation

Proudly Made in the USA.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Liver Chol by Sunshine Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Liver Chol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Liver Chol by Sunshine Naturals

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
2 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Pantothenic Acid

No known
interactions
2 mg per serving Form: D-Calcium Pantothenate

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Choline Bitartrate

Interacts with
16 drugs
240 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline Bitartrate monograph & interactions

Methionine

No known
interactions
110 mg per serving

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...

Methionine monograph & interactions

Niacinamide

Interacts with
124 drugs
10 mg per serving

Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products. It is well established for preventing and t...

Niacinamide monograph & interactions

Vitamin B2

Interacts with
20 drugs
3 mg per serving Form: Riboflavin

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Vitamin B2 monograph & interactions

Vitamin B1

3 mg per serving Form: Thiamine Hydrochloride

Liver concentrate

Interacts with
3 drugs
30 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver concentrate monograph & interactions

Inositol Complex

Interacts with
86 drugs
83 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol Complex monograph & interactions

Vit. B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vit. B6 monograph & interactions

Dessicated Liver

Interacts with
3 drugs
56 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Dessicated Liver monograph & interactions
Interaction report

Liver Chol by Sunshine Naturals Drug Interactions

Want to check YOUR meds against Liver Chol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
445Drugs
428 Moderate 17 Minor

Ingredients driving the most interactions

Vit. B6 210
Niacinamide 124
Inositol Complex 86
Vitamin B12 20
Vitamin B2 20

Individual Drug Interactions

The ingredients in Liver Chol interact with 445 drugs. Click any drug to see the details.

7 of the 11 ingredients in Liver Chol interact with drugs. Each result below shows which ingredient is responsible. Vit. B6 Niacinamide Inositol Complex Vitamin B12 Vitamin B2 Choline Bitartrate Liver concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Liver Chol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vit. B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vit. B6 full monograph & interactions

Niacinamide4 drug types · 124 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialysis.
Several cases of thrombocytopenia have been reported for hemodialysis patients treated with niacinamide 1 gram daily. Hemodialysis patients receiving niacinamide had almost a three-fold higher risk of developing thrombocytopenia when compared with those receiving placebo.

Likelihood Unlikely Evidence D
Carbamazepine (Tegretol)

Niacinamide might increase the levels and adverse effects of carbamazepine.
Plasma levels of carbamazepine were increased in two children given high-dose niacinamide, 60-80 mg/kg/day. This might be due to inhibition of the cytochrome P450 enzymes involved in carbamazepine metabolism. There is not enough data to determine the clinical significance of this interaction.

Likelihood Possible Evidence D
Primidone (Mysoline)

Niacinamide might increase the levels and adverse effects of primidone.
Case reports in children suggest niacinamide 60-100 mg/kg/day reduces hepatic metabolism of primidone to phenobarbital, and reduces the overall clearance rate of primidone; however, there is not enough data to determine the clinical significance of this potential interaction.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that niacinamide may increase the anticoagulant effects of warfarin.
In a case report, a patient on warfarin developed an elevated international normalized ratio (INR) of 8.4 after taking niacinamide 500 mg twice daily for 10 days. The patient's INR was previously stable, ranging between 2 and 3, with no other changes to current medications or diet reported. The elevated INR returned to the therapeutic range after receiving vitamin K and discontinuing niacinamide.

Likelihood Possible Evidence D
Niacinamide full monograph & interactions

Inositol Complex1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol Complex full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions

Vitamin B21 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Vitamin B2 full monograph & interactions

Choline Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline Bitartrate full monograph & interactions

Liver concentrate2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
Liver concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Liver Chol, from the product label.

Sunshine Naturals

See all Sunshine Naturals products
Name
American Naturavit Inc.
City
Miami
State
FL
ZipCode
33166
Phone Number
305-593-5417
Web Address
www.sunshinenaturals.com
Pharmacist Counseling Corner

Liver Chol by Sunshine Naturals: Common Questions

Does Liver Chol by Sunshine Naturals interact with any medications?
Yes. Based on its ingredients, Liver Chol has a known interaction with 445 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liver Chol contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without checking with your doctor first. The niacinamide and liver extract in this product may increase warfarin's blood-thinning effect, raising your bleeding risk. Your doctor may need to monitor your INR (clotting measure) more closely or adjust your dose.
Is this safe to take during pregnancy?
Some ingredients are safe at normal amounts—B12, B2, and pantothenic acid are considered likely safe, and B6 is typically safe at recommended levels for morning sickness. But liver extract carries very high vitamin A, which can harm a developing baby, and choline and methionine supplement doses haven't been fully tested in pregnancy. Talk with your doctor before taking this while pregnant.
Will this give me energy or help with fatigue?
The product contains liver extract and B vitamins often touted for fatigue, but the research doesn't back this up—liver extract is rated possibly ineffective for chronic fatigue syndrome, and we don't have established evidence for the other ingredients on fatigue specifically.
What's the difference between the two liver ingredients in here?
This product has both liver concentrate and desiccated (dried) liver, which are similar—both are whole-food liver products that can contain high levels of vitamin A and iron. They have the same interactions with warfarin and iron medications.
Can I take this with my metformin?
Metformin can lower B12 levels over time, and this product contains B12, so there's a minor interaction to be aware of. Your doctor may want to monitor your B12 periodically if you take both, but it's not a reason to avoid the combination—just something to track.
What happens if I take too much?
High doses of choline (over 3.5 grams daily) can cause fishy body odor, nausea, and vomiting. High doses of vitamin B6 (above 1,000 mg daily) over time can damage nerves, causing numbness or tingling. The other B vitamins are mostly just removed by your body, though niacinamide at very high doses can cause stomach upset. Stick to the label dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liver Chol label
Go deeper

The Full Monographs Behind Liver Chol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph → Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph → Herb & supplement monograph

Methionine

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a normal diet, and supplements are generally no...

Read the full Methionine monograph → Herb & supplement monograph

Niacinamide

Interacts with 124 drugs

Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products. It is well established for preventing and treating vitamin B3 deficiency, and there...

Read the full Niacinamide monograph → Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph → Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph → Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

Liver Chol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 144 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
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Pantothenic Acid 11 references
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Choline 14 references
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Methionine 12 references
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Niacinamide 22 references
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Riboflavin 5 references
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Liver Extract 4 references
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Inositol 14 references
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Vitamin B6 32 references
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See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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