Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Maintenance Probiotics With DDS-1 Ingredients & Drug Interactions

by Multi Flora Probiotics

Maintenance Probiotics With DDS-1 label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Maintenance Probiotics With DDS-1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Maintenance Probiotics With DDS-1 is a dietary supplement by Multi Flora Probiotics with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are B. longum, L. acidophilus DDS(R)-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Maintenance Probiotics With DDS-1 by Multi Flora Probiotics

Ask about any prescription or over-the-counter medication and we check it for interactions with Maintenance Probiotics With DDS-1 by Multi Flora Probiotics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Maintenance Probiotics With DDS-1 by Multi Flora Probiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 4 active ingredients.

This product contains 4 ingredients, 2 of which are active probiotics. The main strains are Bifidobacterium longum and Lactobacillus acidophilus DDS-1, both live microorganisms meant to support your gut.

The other two ingredients are proprietary blends and total cultures that we don't have full detail on. The inactive ingredients are rice dextrin, vegetable cellulose, fructooligosaccharide, vegetable magnesium stearate, and silica — these are the capsule and fillers that help deliver the probiotics.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and gut balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Constipation, Diarrhea, Helicobacter pylori — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Radiation-induced diarrhea.

The evidence is mixed here. L. acidophilus DDS-1 is rated Possibly Effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis — those conditions have some research support.

For other uses like asthma, allergic rhinitis, and age-related cognitive decline, the evidence for both strains is Insufficient Reliable Evidence To Rate, meaning we don't have enough solid data yet. If you're taking this for a specific condition, ask your pharmacist which strain and how much research backs it for your situation.

The evidence, ingredient by ingredient Bifidobacterium Longum Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both strains are generally well tolerated in healthy people, though data are limited — check with your doctor before starting, especially if you're seriously ill or have a weakened immune system. Rare side effects include abdominal discomfort, pain, bloating, flatulence, constipation, and gastrointestinal motor disorder.

In critically ill patients, there have been very rare cases of these probiotics entering the bloodstream and causing infection (bacteremia or sepsis), usually in preterm infants or patients with severe underlying illness. One person reported a dry cough in a trial.

For pregnancy and breastfeeding, B. longum is rated Possibly Safe; we don't have specific safety data on file for L. acidophilus in pregnancy or lactation, so talk with your doctor or pharmacist before using while nursing or pregnant.

Side effects, ingredient by ingredient Bifidobacterium Longum Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, separate them from this product — antibiotics can kill the live probiotics and make them less effective. Ask your pharmacist exactly when to take each one.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a two-strain probiotic that works best for IBS and antibiotic-associated diarrhea — and if you're on antibiotics, space out the timing so the drugs don't kill the live cultures. It's generally well tolerated in healthy adults, but if you're seriously ill, immunocompromised, or pregnant or breastfeeding, clear it with your healthcare provider first.

Altogether, these interactions span 182 individual medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maintenance Probiotics With DDS-1, straight from the product label.

Brand Multi Flora Probiotics
Net contents 60 Veg Cap(s); 5000000000 CFU
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 28810
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maintenance Probiotics With DDS-1 by Multi Flora Probiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
B. longum0 Not Present--
Total Cultures5000000000 CFU--
A Proprietary Probiotic Blend29 mg--
L. acidophilus DDS(R)-10 Not Present--

Other ingredients: Rice Dextrin, Vegetable Cellulose, Fructooligosaccharide, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

{image}Purely Probiotics Founded in 1979, UAS LifeSciences has delivered the highest quality, science-backed probiotics to health conscious consumers for more than thirty years. Today, UAS LifeSciences remains dedicated to producing only probiotics and is fully integrated to include formulation, testing, blending, packaging and shipping at our state-of-the-art manufacturing facility specifically designed to meet the rigorous requirements for the highest quality probiotics. Our staff includes some of the most experienced scientists in the industry and we regularly participate in clinical studies. Probiotics are not just another product for us, it is all we do, it is all we’ve ever done. UAS LifeSciences is, and always will be, PURELY PROBIOTICS.

This strain is a core component of all Multi-Flora formulations. When combined with other well-tested probiotic strains, the result is a formula that is perfectly designed to maximize the benefits for each individual.

{image} Strain Selection Not all probiotic strains are created equal.

When it comes to probiotics, it's not about the number of strains, it's about selecting the right strains in the first place.

Naturally Acid & Bile Resistant {image} Compatibility with gut microbes is important for probiotics.

Live cultures that can naturally withstand stomach acid and bile without the need for chemical coatings are an integral part of all blends.

{image} Perfecting Probiotics Probiotics must be alive to provide benefits. A combination of science and art is needed to select and manufacture probiotics that remain viable throughout processing and distribution. 30 years of experience has resulted in manufacturing expertise that gives you the top-quality products you can trust.

supports digestive & immune health

Laboratory tested to meet strict standards for potency and identity.

Brand IP Statement(s)

The DDS-1 Difference {image} Lactobacillus acidophilus DDS(R)-1, the trademarked superstrain of UAS LifeSciences, has been the subject of numerous studies on probiotic stability, intestinal compatibility and health benefits.

DIRECTIONS: For best results take 1 capsule per day before or during meals.

Formula

Multi-Flora is formulated with exceptionally resilient, scientifically-validated strains like Lactobacillus acidophilus DDS(R)-1.

Formulation

Multi-Flora uses tested probiotic strains that thrive in the gut and are non-GMO, non-dairy, gluten free, soy free, corn free, preservative free and vegan.

Multi-Flora uses tested probiotic strains that thrive in the gut and are non-GMO, non-dairy, gluten free, soy free, corn free, preservative free and vegan.

NON-DAIRY NON-GMO GLUTEN FREE SOY FREE PRESERVATIVE FREE

VEGAN

FDA Statement of Identity

PROBIOTIC SUPPLEMENT

Precautions

CAUTION: ~ Do not take if seal is broken

~ Keep out of reach of children

~ As with any supplement, if you are pregnant, nursing, have a medical condition or taking medication, consult your health practitioner before use

Storage

Room temperature stable for two years. Refrigerate after opening.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

{crescent moon}M(R)

OK D

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Maintenance Probiotics With DDS-1 by Multi Flora Probiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Maintenance Probiotics With DDS-1 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Maintenance Probiotics With DDS-1 by Multi Flora Probiotics

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

B. longum

Interacts with
182 drugs
0 Not Present per serving

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most...

B. longum monograph & interactions

Total Cultures

5000000000 CFU per serving

A Proprietary Probiotic Blend

29 mg per serving

L. acidophilus DDS(R)-1

Interacts with
182 drugs
0 Not Present per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

L. acidophilus DDS(R)-1 monograph & interactions

Other (inactive) ingredients: Rice Dextrin, Vegetable Cellulose, Fructooligosaccharide, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maintenance Probiotics With DDS-1 by Multi Flora Probiotics Drug Interactions

Want to check YOUR meds against Maintenance Probiotics With DDS-1?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

B. longum 182
L. acidophilus DDS(R)-1 182

Individual Drug Interactions

The ingredients in Maintenance Probiotics With DDS-1 interact with 182 drugs. Click any drug to see the details.

2 of the 4 ingredients in Maintenance Probiotics With DDS-1 interact with drugs. Each result below shows which ingredient is responsible. B. longum L. acidophilus DDS(R)-1

Each ingredient & the kinds of drugs it affects

For each ingredient in Maintenance Probiotics With DDS-1 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

B. longum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
B. longum full monograph & interactions

L. acidophilus DDS(R)-11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
L. acidophilus DDS(R)-1 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Maintenance Probiotics With DDS-1, from the product label.

Multi Flora Probiotics

See all Multi Flora Probiotics products
Name
UASLifeSciences The Probiotic Company
Street Address
555 N 72nd Avenue
City
Wausau
State
WI
ZipCode
54401
Phone Number
715.849.3333
Pharmacist Counseling Corner

Maintenance Probiotics With DDS-1 by Multi Flora Probiotics: Common Questions

Does Maintenance Probiotics With DDS-1 by Multi Flora Probiotics interact with any medications?
Yes. Based on its ingredients, Maintenance Probiotics With DDS-1 has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Maintenance Probiotics With DDS-1 contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic at the same time as my antibiotic?
No — antibiotics can kill the live organisms in the probiotic and make it less effective. Separate them by a few hours, or ask your pharmacist for the best timing based on your specific antibiotic.
Does this probiotic help with IBS?
The L. acidophilus DDS-1 strain in this product is rated Possibly Effective for IBS, meaning there's some research support. Results vary by person, so give it time and talk to your doctor if you're not seeing improvement.
Is it safe to take while breastfeeding?
B. longum is rated Possibly Safe during breastfeeding, but we don't have enough data on L. acidophilus to know either way. Talk with your doctor or pharmacist before using while nursing — they can give you personalized advice.
What are the side effects?
Most people tolerate it well. Rarely, people report abdominal discomfort, bloating, flatulence, or constipation. In one trial, a person reported a dry cough. Serious infections are very rare and mostly happen in critically ill patients.
Can I take this if I'm seriously ill or on immunosuppressants?
Caution is needed — check with your doctor first. There have been rare cases of these probiotics causing serious infections in critically ill or immunocompromised patients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maintenance Probiotics With DDS-1 is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maintenance Probiotics With DDS-1 label
Go deeper

The Full Monographs Behind Maintenance Probiotics With DDS-1’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Maintenance Probiotics With DDS-1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 36 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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