Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Junior Probiotics With DDS-1 Ingredients & Drug Interactions

by Multi Flora Probiotics

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Junior Probiotics With DDS-1 is a dietary supplement by Multi Flora Probiotics with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L. acidophilus DDS(R)-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Junior Probiotics With DDS-1 by Multi Flora Probiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Total Cultures” is listed as a grouped ingredient — the label gives one combined amount (5,000,000,000 CFU) without saying how much of each component you get.

This powder contains 3 active probiotic ingredients: L. acidophilus DDS-1 (a well-studied strain of beneficial bacteria), B. lactis, and a proprietary blend of additional probiotic cultures. These are live microorganisms meant to support gut health.

The product also includes rice dextrin, fructooligosaccharide (a prebiotic fiber that feeds probiotics), and silica as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports digestive and immune health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Colic, Constipation, Helicobacter pylori — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Lactose intolerance.

L. acidophilus DDS-1 is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. For atopic disease (allergic conditions), the evidence suggests it's possibly ineffective.

For acute respiratory distress syndrome, there isn't enough reliable evidence to rate it either way. The other ingredients in this product haven't been rated in the data we hold.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L. acidophilus is generally well tolerated in healthy adults and children. That said, because it contains live microorganisms, there is a theoretical risk of infection in vulnerable patients — cases of bacteremia, sepsis, and other serious infections have been documented in the medical literature, though most occurred in people with existing health conditions.

Common side effects are uncommon but can include stomach discomfort, bloating, flatulence, diarrhea, and burping when taken with other probiotics. If you have a weakened immune system, are hospitalized, or have serious illness, talk with your doctor before starting this product.

Data on use in pregnancy is limited; there isn't enough information to know whether it's safe during pregnancy or breastfeeding, so discuss it with your doctor or pharmacist first.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotics are the key medication type to separate from this product. Taking them at the same time will reduce the probiotic's effectiveness because the antibiotic will kill the live cultures.

Space them out by a few hours — your doctor or pharmacist can help with the best schedule for you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with certain digestive and infection-related conditions, though evidence is mixed. The main caution is timing it away from antibiotics — they'll cancel each other out.

If you're pregnant, breastfeeding, or have a compromised immune system, check with your doctor or pharmacist before starting. Run your medications through our search tool to catch any interactions with your specific prescriptions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Junior Probiotics With DDS-1, straight from the product label.

Brand Multi Flora Probiotics
Net contents 60 Grams Powder; 2.1 oz.; 5000000000 CFU
Market status On market
Date entered into DSLD Dec 24, 2013
DSLD ID 28818
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Junior Probiotics With DDS-1 by Multi Flora Probiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s), 1 Gram(s)
Maximum serving Sizes:
0.25 Teaspoon(s), 1 Gram(s)
Servings per container
60
IngredientAmount% DV
B. lactis0 Not Present--
Total Cultures5000000000 CFU--
A Proprietary Probiotic Blend18 mg--
L. acidophilus DDS(R)-10 Not Present--

Other ingredients: Rice Dextrin, Fructooligosaccharide, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

supports digestive & immune health

Laboratory tested to meet strict standards for potency and identity.

{image}Purely Probiotics Founded in 1979, UAS LifeSciences has delivered the highest quality, science-backed probiotics to health conscious consumers for more than thirty years. Today, UAS LifeSciences remains dedicated to producing only probiotics and is fully integrated to include formulation, testing, blending, packaging and shipping at our state-of-the-art manufacturing facility specifically designed to meet the rigorous requirements for the highest quality probiotics. Our staff includes some of the most experienced scientists in the industry and we regularly participate in clinical studies. Probiotics are not just another product for us, it is all we do, it is all we’ve ever done. UAS LifeSciences is, and always will be, PURELY PROBIOTICS.

This strain is a core component of all Multi-Flora formulations. When combined with other well-tested probiotic strains, the result is a formula that is perfectly designed to maximize the benefits for each individual.

{image} Strain Selection Not all probiotic strains are created equal.

When it comes to probiotics, it's not about the number of strains, it's about selecting the right strains in the first place.

Naturally Acid & Bile Resistant {image} Compatibility with gut microbes is important for probiotics.

Live cultures that can naturally withstand stomach acid and bile without the need for chemical coatings are an integral part of all blends.

{image} Perfecting Probiotics Probiotics must be alive to provide benefits. A combination of science and art is needed to select and manufacture probiotics that remain viable throughout processing and distribution. 30 years of experience has resulted in manufacturing expertise that gives you the top-quality products you can trust.

FDA Statement of Identity

PROBIOTIC SUPPLEMENT

Formulation

NON-DAIRY NON-GMO GLUTEN FREE SOY FREE PRESERVATIVE FREE

VEGAN

Multi-Flora uses tested probiotic strains that thrive in the gut and are non-GMO, non-dairy, gluten free, soy free, corn free, preservative free and vegan.

Multi-Flora uses tested probiotic strains that thrive in the gut and are non-GMO, non-dairy, gluten free, soy free, corn free, preservative free and vegan.

Brand IP Statement(s)

DIRECTIONS: For best results take ¼ Teaspoon with water or food. Consume soon after mixing.

The DDS-1 Difference {image} Lactobacillus acidophilus DDS(R)-1, the trademarked superstrain of UAS LifeSciences, has been the subject of numerous studies on probiotic stability, intestinal compatibility and health benefits.

Precautions

CAUTION: ~ Do not take if seal is broken

~ Keep out of reach of children

~ As with any supplement, if you are pregnant, nursing, have a medical condition or taking medication, consult your health practitioner before use

Storage

Room temperature stable for two years. Refrigerate after opening.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

{crescent moon}M(R)

OK D

Formula

Multi-Flora is formulated with exceptionally resilient, scientifically-validated strains like Lactobacillus acidophilus DDS(R)-1.

See for yourself

Junior Probiotics With DDS-1 by Multi Flora Probiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Junior Probiotics With DDS-1 by Multi Flora Probiotics

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Total Cultures

5000000000 CFU per serving

A Proprietary Probiotic Blend

18 mg per serving

Other (inactive) ingredients: Rice Dextrin, Fructooligosaccharide, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Junior Probiotics With DDS-1 by Multi Flora Probiotics Drug Interactions

Want to check YOUR meds against Junior Probiotics With DDS-1?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Junior Probiotics With DDS-1 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L. acidophilus DDS(R)-11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Junior Probiotics With DDS-1, from the product label.

Multi Flora Probiotics

See all Multi Flora Probiotics products
Name
UASLifeSciences The Probiotic Company
Street Address
555 N 72nd Avenue
City
Wausau
State
WI
ZipCode
54401
Phone Number
715.849.3333
Pharmacist Counseling Corner

Junior Probiotics With DDS-1 by Multi Flora Probiotics: Common Questions

Does Junior Probiotics With DDS-1 by Multi Flora Probiotics interact with any medications?
Yes. Based on its ingredients, Junior Probiotics With DDS-1 has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Junior Probiotics With DDS-1 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
You can take both, but not at the same time. Antibiotics kill the live bacteria in probiotics, so separate the doses by a few hours. Ask your pharmacist or doctor which one to take first — timing matters, and they can give you the right schedule for your specific antibiotic.
Is this safe during pregnancy?
The data on L. acidophilus in pregnancy is limited. There isn't enough information to say whether it's safe or unsafe during pregnancy, so talk with your doctor or pharmacist for personalized advice before taking it.
What does L. acidophilus DDS-1 actually do?
It's a strain of beneficial bacteria that may help with irritable bowel syndrome, antibiotic-related diarrhea, bacterial vaginosis, and certain infections. The evidence is strongest for these conditions, though it's not a cure-all.
What side effects might I notice?
Most people tolerate it fine. A small number of people experience stomach discomfort, bloating, gas, or diarrhea, especially when taking it with other probiotics. These effects are usually mild and uncommon.
Does this product have any fillers?
Yes — it contains rice dextrin, fructooligosaccharide (a fiber that feeds the probiotics), and silica. The fructooligosaccharide is actually a prebiotic, so it helps the live cultures work better.
Is it safe for children?
L. acidophilus is generally well tolerated in children. That said, it contains live microorganisms, so if your child has a weakened immune system or serious illness, check with their doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Junior Probiotics With DDS-1 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Junior Probiotics With DDS-1 label
Sources

Sources & How We Checked

Junior Probiotics With DDS-1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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