Matrix 5000 Ingredients & Drug Interactions
by Elon
What is this page for?
First and foremost: checking Matrix 5000 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Matrix 5000 is a dietary supplement by Elon with 3 active ingredients. Its ingredients are commonly taken for hair, skin, and nail health, bone health and osteoporosis, joint and connective tissue support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Cysteine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Matrix 5000 by Elon
Ask about any prescription or over-the-counter medication and we check it for interactions with Matrix 5000 by Elon — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Matrix 5000 by Elon
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Matrix 5000 contains 3 active ingredients. Silicon dioxide is a mineral form of silicon used here for possible support of bone health.
Biotin is a B vitamin that's effective for biotin deficiency and may have a role in skin and hair health, though the evidence for some of those uses is limited. L-cysteine hydrochloride is an amino acid that's included for hair and skin support, though the scientific evidence for it remains unproven.
The tablet also contains several inactive ingredients — dicalcium phosphate, microcrystalline cellulose, hypromellose, magnesium stearate, hydroxypropyl methylcellulose, titanium dioxide, and natural flavors — which are fillers, binders, and other agents that hold the tablet together and help it dissolve.
Does it work?
Strong evidence
The evidence for what this product can do is mixed. Biotin is effective for treating biotin deficiency, though that's not common in people eating a normal diet.
Silicon dioxide is possibly effective for osteoporosis, which means the evidence is suggestive but not conclusive. For everything else listed on the label — hair loss, dental health, multiple sclerosis, and dermatitis — the evidence we hold is either insufficient or suggests the ingredient may not work.
Talk to your pharmacist about whether any of these uses fits what you're hoping this supplement will do for you.
How safe is it?
Well-documented data
Silicon dioxide and biotin are both rated likely safe in pregnancy and lactation at normal food and supplement doses. L-cysteine hydrochloride is also rated likely safe in pregnancy and lactation, though long-term high-dose safety hasn't been well studied for any of these ingredients.
Silicon dioxide is generally well tolerated from food and most supplements, but high-dose or long-term safety is not established. Biotin is similarly well tolerated, even at fairly high doses, because your body removes excess in urine — though at very high doses, mild diarrhea has been rarely reported.
With L-cysteine, we have no adverse effects reported in the data we hold, but supplement-level doses haven't been studied extensively either. If you're pregnant, breastfeeding, or taking high-dose versions of any of these, check with your doctor or pharmacist first.
Meds to double-check
Moderate interaction found
If you take antidiabetes drugs—like metformin, insulin, sulfonylureas, or GLP-1 agonists—double-check with your pharmacist before starting this product. L-cysteine may increase the risk of low blood sugar (Moderate severity).
No other interactions are documented for the ingredients we could check, but use the medication search tool on this page to look up your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Matrix 5000 might appeal to you if you're interested in bone, hair, or skin support and you're willing to take a product with unproven claims. The one real caution is if you take diabetes medication — L-cysteine can theoretically lower your blood sugar further.
Run your exact medications through our search tool before you start, and if you're pregnant, breastfeeding, or on any prescription drugs, talk to your pharmacist.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Matrix 5000, straight from the product label.
| Brand | Elon |
|---|---|
| Barcode (UPC) | 058869125013 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 319976 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Matrix 5000 by Elon, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Silicon Dioxide | 10 mg | -- |
| Biotin | 5000 mcg | 16667% |
| L-Cysteine Hydrochloride | 50 mg | -- |
Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Hydroxypropyl Methylcellulose, Titanium Dioxide, Natural Flavors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports healthier and stronger hair Three essential nutritional building blocks to promote hair strength, luster, and body from the root. Our extended-release formula promotes maximum nourishment to support stronger and healthier hair.
Healthier, stronger hair
Extended-release
Seals/Symbols
Made in the USA
Formulated in USA
Formula
Biotin, L-Cysteine, & Silicon Dioxide
General Statements
Dermatologist recommended
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one (1) tablet daily.
Precautions
Caution: Do not exceed recommended serving size.
Keep out of reach of children.
Do not use if safety seal is damaged.
Storage
Store in a cool dry place.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Matrix 5000 by Elon label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Matrix 5000 by Elon
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Silicon Dioxide
No knowninteractions
Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...
Silicon Dioxide monograph & interactionsBiotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsL-Cysteine Hydrochloride
Interacts with86 drugs
L-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and su...
L-Cysteine Hydrochloride monograph & interactionsOther (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Hypromellose, Magnesium Stearate, Hydroxypropyl Methylcellulose, Titanium Dioxide, Natural Flavors. These complete the product’s ingredient list but are not active constituents.
Matrix 5000 by Elon Drug Interactions
HelloPharmacist Interaction Report
Matrix 5000 by Elon contains one ingredient with documented drug interactions: L-cysteine hydrochloride.
This ingredient may increase the risk of low blood sugar (hypoglycemia) if you take antidiabetes medications. The effect is theoretical based on animal research, but it's a Moderate-severity concern worth discussing with your pharmacist before you start, especially if your blood sugar is already hard to control.
Read the full breakdown — every affected drug type, severity by severity
Silicon dioxide and biotin, the other two active ingredients, have no interactions documented in our data. Altogether, these interactions span 85 individual medications.
Because the interaction data we hold is incomplete for some ingredients, and because we can't check every medication combination in real time, use the search tool on this page to look up your exact drugs. That's the fastest way to know if this product is safe for you to take alongside what you're on now.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Matrix 5000?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Matrix 5000 interact with 86 drugs. Click any drug to see the details.
1 of the 3 ingredients in Matrix 5000 interact with drugs. Each result below shows which ingredient is responsible. L-Cysteine Hydrochloride
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Matrix 5000 — through 1 ingredient. Tap an ingredient for the detail:
L-cysteine HydrochlorideAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full L-cysteine Hydrochloride + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Matrix 5000 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Cysteine Hydrochloride
Antidiabetes Drugs
Theoretically, taking L-cysteine supplements with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that L-cysteine can have hypoglycemic effects.
Brand information
Manufacturer and brand details for Matrix 5000, from the product label.
Elon
- Name
- Dartmouth Pharmaceuticals
- Street Address
- 1828 Touby Pike
- City
- Kokomo
- State
- IN
- ZipCode
- 46901
- Phone Number
- 800-414-3566
- Web Address
- www.elonessentials.com
Matrix 5000 by Elon: Common Questions
Does Matrix 5000 by Elon interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is biotin safe if I'm pregnant?
Will this help my hair grow?
Can I take this if I have diabetes and take medication for it?
What is L-cysteine, and why is it in here?
Are there any side effects I should know about?
Does this product have fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Matrix 5000 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Matrix 5000’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Silicon
Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for hair, skin, nail, and bone health. Some s...
Read the full Silicon monograph → Herb & supplement monographBiotin
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...
Read the full Biotin monograph → Herb & supplement monographL-cysteine
Interacts with 86 drugsL-cysteine is a sulfur-containing amino acid your body uses to make proteins and the antioxidant glutathione. Most people get enough from food, and supplements are usually well tolerated, bu...
Read the full L-cysteine monograph →Sources & How We Checked
Matrix 5000's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Silicon 19 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
- Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
- Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
- Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
- Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
- Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
- Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
- McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
- Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
- Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
- Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
- Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
- Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
- McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
- Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
- Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
- Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
- Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
L-cysteine 2 references
- Dowlati Y, Maheux M, Meyer JH. The effect of oral L-cysteine on breast milk and plasma cysteine concentrations. Neuropsychiatr Dis Treat 2020;16:3163-3172.
- Lee S, Han KH, Nakamura Y, et al. Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet. Biosci Biotechnol Biochem 2013;77(7):1430-4.
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