Mega Lactophilus Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking Mega Lactophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mega Lactophilus is a dietary supplement by DC with 5 active ingredients. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Lactobacillus bulgaricus, Citrus Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mega Lactophilus by DC
Ask about any prescription or over-the-counter medication and we check it for interactions with Mega Lactophilus by DC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mega Lactophilus by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Mega Lactophilus contains 5 active ingredients: four strains of live probiotic bacteria (Lactobacillus acidophilus, Bifidobacterium animalis lactis, Lactobacillus salivarius, and Lactobacillus bulgaricus) plus citrus pectin. The probiotics are meant to support your gut flora; pectin is a soluble fiber.
The capsule also contains inactive ingredients — calcium phosphate, gelatin, vegetable magnesium stearate, and calcium silicate — which are fillers and binders.
Does it work?
Moderate evidence
The evidence is mixed and often limited. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, though it's possibly ineffective for atopic disease and there isn't enough reliable evidence yet for acute respiratory distress syndrome.
Lactobacillus bulgaricus doesn't have solid evidence for the conditions that have been studied — acne, hay fever, antibiotic-associated diarrhea, asthma, fatty liver disease, and the common cold all fall into insufficient evidence territory. Pectin (citrus pectin) is possibly effective for high cholesterol but has insufficient evidence for prediabetes and radiation exposure.
We hold no effectiveness data for the other two probiotic strains.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children, though you should check with your doctor before starting it. The main concern is that in rare cases, the live bacteria have been linked to serious infections like bacteremia or endocarditis — mostly in people whose immune systems were already compromised or in whom the bacteria moved from their normal location in the gut.
More commonly, the combination of multiple probiotics can cause mild gastrointestinal side effects including stomach discomfort, bloating, gas, diarrhea, or vomiting, though these are uncommon. Lactobacillus bulgaricus is generally well tolerated in healthy people but calls for caution in anyone who is very ill or immunocompromised.
Pectin is well tolerated from food and typical supplement amounts; the most common side effects are gas, loose stools, diarrhea, and mild cramping. Rarely, people sensitive to pectin can have allergic reactions including anaphylaxis.
Neither Lactobacillus ingredient has pregnancy or breastfeeding safety data on file; pectin is considered likely safe in pregnancy but only possibly safe during breastfeeding — talk with your doctor or pharmacist before using this product if you are pregnant or nursing.
Meds to double-check
Moderate interaction found
Before you take this, double-check with your pharmacist if you're on digoxin (a heart medication), tetracycline antibiotics, lovastatin for cholesterol, or any antibiotic. All of these have documented Moderate severity interactions with ingredients in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Consider Mega Lactophilus if you have irritable bowel syndrome, antibiotic-associated diarrhea, or related gut issues and your doctor gives the okay. Be extra careful if you take digoxin, antibiotics, tetracycline, or lovastatin — those need a real conversation with your pharmacist first.
Anyone with a compromised immune system should check with their doctor before starting. Run your medications through our checker on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mega Lactophilus, straight from the product label.
| Brand | DC |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 11, 2022 |
| DSLD ID | 266602 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mega Lactophilus by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus acidophilus | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Lactobacillus salivarius | 0 NP | -- |
| Lactobacillus bulgaricus | 0 NP | -- |
| Citrus Pectin | 200 mg | -- |
| Blend of 4 strains of Probiotic Bacteria | 0 NP | -- |
Other ingredients: Calcium Phosphate, Gelatin, Vegetable Magnesium Stearate, Calcium Silicate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 2 capsules daily, preferably with a meal.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing do not take this product.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
New higher potency
Gluten free
Nutritionally supports healthy intestinal flora
No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish and is sodium free.
Made in USA
Storage
Keep tightly closed. Refrigerate after opening.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Quali Pure
Formula
6 billion good bacteria Probiotic freeze-dried with pectin
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mega Lactophilus by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mega Lactophilus by DC
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Citrus Pectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Citrus Pectin monograph & interactionsBlend of 4 strains of Probiotic Bacteria
- › Lactobacillus acidophilus
- › Bifidobacterium animalis lactis
- › Lactobacillus salivarius
- › Lactobacillus bulgaricus
Other (inactive) ingredients: Calcium Phosphate, Gelatin, Vegetable Magnesium Stearate, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.
Mega Lactophilus by DC Drug Interactions
HelloPharmacist Interaction Report
Mega Lactophilus by DC contains live probiotic bacteria and pectin, and it does interact with several medication types.
The most serious concern is with digoxin (Lanoxin), a heart medication: pectin in this product might reduce how much digoxin your body absorbs, potentially making it less effective. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Antibiotics are another key concern — both the Lactobacillus acidophilus and Lactobacillus bulgaricus in this product could theoretically have their effectiveness reduced if you take them at the same time as antibiotics, since antibiotics can kill the live organisms in the product. Tetracycline antibiotics (a specific class) also interact with the pectin here, which might lower how much tetracycline your body absorbs.
Both are Moderate severity.
You'll also want to check lovastatin (Mevacor), a cholesterol medication — pectin may reduce its absorption and lower its effectiveness.
We couldn't check three of the probiotic strains in this product — Bifidobacterium animalis lactis, Lactobacillus salivarius, and the blend label — for interactions, so there may be more we don't have data on. Run your exact medications through the checker below before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mega Lactophilus?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mega Lactophilus interact with 188 drugs. Click any drug to see the details.
3 of the 5 ingredients in Mega Lactophilus interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Lactobacillus bulgaricus Citrus Pectin
AmikacinAmikin, Arikayce
How Amikacin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amikacin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin Veterinary interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Clavulanate Potassium interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Mega Lactophilus — through 3 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Amphotericin, Tetracycline interactionCitrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Amphotericin, Tetracycline interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin, Sulbactam interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Avibactam Sodium, Ceftazidime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Azithromycin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Aztreonam interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacampicillin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacitracin interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Benznidazole interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Mega Lactophilus — through 3 ingredients. Tap an ingredient for the detail:
Citrus PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Citrus Pectin + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Capreomycin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Carbenicillin Indanyl Sodium interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefaclor interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefadroxil interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefamandole interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefazolin interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefdinir interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefditoren Pivoxil interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefepime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefiderocol Sulfate Tosylate interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefixime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefmetazole interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefonicid interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefoperazone interactionLactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Mega Lactophilus — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Bulgaricus + Cefotaxime interactionLactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mega Lactophilus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Lactobacillus bulgaricus
Antibiotic Drugs
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.
Citrus Pectin
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Mega Lactophilus, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
Mega Lactophilus by DC: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mega Lactophilus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Pectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographLactobacillus Delbrueckii
Interacts with 182 drugsLactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...
Read the full Lactobacillus Delbrueckii monograph →Sources & How We Checked
Mega Lactophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 35 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Lactobacillus Delbrueckii 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
- Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
- Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
- Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
- Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
- Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
- Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.
See these in context on the Lactobacillus Delbrueckii monograph →
Pectin 11 references
- Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
- Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
- Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
- Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
- Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC