Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Myo-Mag Ingredients & Drug Interactions

by Health Products Distributors

Myo-Mag label
See full label image
Capsule Category: Multi-vitamin And Mineral (mvm)
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Myo-Mag against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Myo-Mag is a dietary supplement by Health Products Distributors with 6 active ingredients. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 515 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Magnesium, Vitamin B-6, Malic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Myo-Mag by Health Products Distributors

Ask about any prescription or over-the-counter medication and we check it for interactions with Myo-Mag by Health Products Distributors — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Myo-Mag by Health Products Distributors

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Myo-Mag contains six active ingredients. Thiamine (vitamin B1), riboflavin (vitamin B2), and vitamin B-6 are B vitamins that support energy and nerve function.

Magnesium is a mineral involved in muscle and bone health, and manganese is a trace mineral. Malic acid is an organic compound.

The product also contains inactive ingredients — glycine, hypromellose, microcrystalline cellulose, and silica — which are excipients that help form and stabilize the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Magnesium and nutrient supplementation.
  • We looked for evidence on: Anxiety, Constipation, Cognitive function, Fatigue, Fibromyalgia, Hypertension — and 4 related terms.
  • The strongest evidence on file: Magnesium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Magnesium is rated "Possibly Ineffective" for Muscle cramps.
  • Also on file: Vitamin B6 is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Cognitive function, Fibromyalgia, Hypertension.

Evidence varies by ingredient and intended use. Thiamine is effective for thiamine deficiency and Wernicke-Korsakoff syndrome (a serious neurological condition from thiamine lack); it's possibly effective for dysmenorrhea (menstrual pain) but possibly ineffective as a mosquito repellent or for heart failure.

Vitamin B-6 is effective for sideroblastic anemia and pyridoxine-dependent epilepsy, and likely effective for lowering homocysteine (a blood marker). Magnesium is effective for dyspepsia (indigestion), constipation, and low magnesium levels.

For manganese deficiency, manganese is effective; for other uses in this product (hay fever, osteoporosis, COPD, obesity, osteoarthritis), the evidence is insufficient to rate. Riboflavin's effectiveness is not rated in our data.

Malic acid is possibly effective for dry mouth but has insufficient evidence for acne, GERD, fatigue, fibromyalgia, or psoriasis.

The evidence, ingredient by ingredient Thiamine Manganese Vitamin B6 Malic Acid Riboflavin Magnesium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients are generally well tolerated at normal doses. Thiamine is very safe orally and is needed in pregnancy and breastfeeding at recommended levels.

Riboflavin is safe and needed during both pregnancy and breastfeeding. Magnesium is safe at recommended amounts, though it's needed in pregnancy and breastfeeding only under a doctor's guidance.

Malic acid is likely safe in pregnancy and breastfeeding but has limited supplement safety data. Vitamin B-6 and manganese require caution at high doses: vitamin B-6 over time at high doses can damage nerves (sensory neuropathy), and manganese at high doses can cause serious nerve damage resembling Parkinson disease and liver injury.

Manganese is generally well tolerated at appropriate doses but amounts in foods and prenatal vitamins are appropriate; avoid extra high-dose supplements unless your doctor advises otherwise. Common side effects from these ingredients may include nausea, diarrhea, headache, and (with riboflavin at higher doses) bright yellow urine.

No pregnancy or breastfeeding rating is on file for manganese or vitamin B-6.

Side effects, ingredient by ingredient Thiamine Manganese Vitamin B6 Malic Acid Riboflavin Magnesium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Manganese, Vitamin B6, Riboflavin, Thiamine, Magnesium, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 515 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Myo-Mag, check your medications against these types: levodopa/carbidopa (Major severity — magnesium reduces its effect); antihypertensive drugs, skeletal muscle relaxants, potassium-sparing diuretics, calcium channel blockers, sulfonylureas, bisphosphonates, and tetracycline antibiotics (all Moderate — magnesium, vitamin B-6, manganese, or malic acid may reduce their effect or increase their side effects); phenobarbital and phenytoin seizure medications (Moderate — vitamin B-6 at high doses may reduce effectiveness); antipsychotic drugs (Moderate — manganese toxicity risk); quinolone antibiotics (Moderate — magnesium and manganese reduce absorption); amiodarone (Moderate — vitamin B-6 may worsen photosensitivity); riboflavin with tetracyclines (Moderate); and trimethoprim (Minor — thiamine may increase levels). Use the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Myo-Mag combines B vitamins, minerals, and malic acid — useful if you're deficient in thiamine, magnesium, or manganese, or seeking support for indigestion or constipation. Be especially cautious if you take Parkinson's medication (levodopa/carbidopa), blood pressure drugs, seizure medications, diabetes drugs, or antibiotics.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or taking any prescription medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Myo-Mag, straight from the product label.

Brand Health Products Distributors
Barcode (UPC) 852347006371
Net contents 100 Veggie Cap(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 254920
Product type Multi-vitamin And Mineral (mvm)
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Myo-Mag by Health Products Distributors, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
852347006371
IngredientAmount% DV
Thiamine10 mg833%
Manganese5 mg217%
Vitamin B-65 mg294%
Malic Acid300 mg--
Riboflavin10 mg769%
Magnesium100 mg24%

Other ingredients: Glycine, Hypromellose, Microcrystalline Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Creating health naturally!

Formula

Magnesium and Malic Acid plus synergistic nutrients

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1 capsule with food one or more times dialy or as directed by a health care professional.

Formulation

Does Not Contain: Wheat, gluten, rye, oats, corn, yeast, egg, dairy, soy, sugar, GMOs, wax, or preservatives.

Storage

Store in a cool, dry place

Precautions

Keep out of reach of children

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Myo-Mag by Health Products Distributors label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Myo-Mag label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Myo-Mag by Health Products Distributors

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Thiamine

Interacts with
3 drugs
10 mg per serving Form: Thiamine Hydrochloride

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Manganese

Interacts with
83 drugs
5 mg per serving Form: Manganese Glycinate

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Vitamin B-6

Interacts with
210 drugs
5 mg per serving Form: Pyridoxal 5-Phosphate

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B-6 monograph & interactions

Malic Acid

Interacts with
172 drugs
300 mg per serving Form: Magnesium Malate

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain....

Malic Acid monograph & interactions

Riboflavin

Interacts with
20 drugs
10 mg per serving Form: Riboflavin, Riboflavin 5-Phosphate

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Magnesium

Interacts with
295 drugs
100 mg per serving Form: Magnesium Carbonate, Magnesium Glycinate, Magnesium Malate

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Other (inactive) ingredients: Glycine, Hypromellose, Microcrystalline Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Myo-Mag by Health Products Distributors Drug Interactions

Want to check YOUR meds against Myo-Mag?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
515Drugs
6 Major 398 Moderate 111 Minor

Ingredients driving the most interactions

Magnesium 295
Vitamin B-6 210
Malic Acid 172
Manganese 83
Riboflavin 20

Individual Drug Interactions

The ingredients in Myo-Mag interact with 515 drugs. Click any drug to see the details.

6 of the 6 ingredients in Myo-Mag interact with drugs. Each result below shows which ingredient is responsible. Magnesium Vitamin B-6 Malic Acid Manganese Riboflavin Thiamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Myo-Mag with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnesium15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B
Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D
Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B
Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D
Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B
Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D
Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D
Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A
Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B
Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B
Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B
Magnesium full monograph & interactions

Vitamin B-65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B-6 full monograph & interactions

Malic Acid1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, malic acid might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that malic acid isolated from tagetes roots can reduce mean arterial blood pressure.

Likelihood Possible Evidence D
Malic Acid full monograph & interactions

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
Thiamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Myo-Mag, from the product label.

Health Products Distributors

See all Health Products Distributors products
Name
Health Products Distributors, Inc.
Street Address
1210 W American Ave
City
Oracle
State
AZ
ZipCode
85623
Pharmacist Counseling Corner

Myo-Mag by Health Products Distributors: Common Questions

Does Myo-Mag by Health Products Distributors interact with any medications?
Yes. Based on its ingredients, Myo-Mag has a known interaction with 515 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Myo-Mag contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Myo-Mag safe to take if I'm pregnant or breastfeeding?
Several ingredients are rated likely safe in pregnancy and breastfeeding at recommended amounts — thiamine, riboflavin, magnesium, and malic acid. Manganese and vitamin B-6 have no safety rating on file for pregnancy or breastfeeding, so there isn't enough data to know either way. Talk with your doctor or pharmacist for personalized advice before using this product while pregnant or breastfeeding.
Will Myo-Mag help with muscle cramps or fibromyalgia?
Magnesium is effective for indigestion and constipation, and the B vitamins support nerve and energy function, but malic acid — sometimes marketed for fibromyalgia — has insufficient evidence to rate its effectiveness for that use. If you're interested in this product for muscle or fibromyalgia symptoms, check with your doctor about whether it's right for you.
What are the main side effects I should watch for?
Most people tolerate these ingredients well at recommended doses. The most common side effects are nausea, diarrhea, headache, and gastrointestinal irritation from magnesium. At higher doses, vitamin B-6 can damage nerves, and manganese can cause serious nerve and liver problems. Riboflavin may turn your urine bright yellow, which is harmless. If you experience nausea, diarrhea, or unusual symptoms, stop and talk to your pharmacist.
Can I take Myo-Mag with my blood pressure medication?
Magnesium, vitamin B-6, and malic acid all have the potential to add to blood-pressure-lowering effects when combined with antihypertensive drugs — a Moderate interaction. Your doctor may need to adjust your dose or monitor your blood pressure more closely. Check with your pharmacist or doctor before adding this product to your routine.
Does Myo-Mag contain any inactive fillers?
Yes. The inactive ingredients are glycine, hypromellose, microcrystalline cellulose, and silica — these help form and stabilize the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Myo-Mag label
Go deeper

The Full Monographs Behind Myo-Mag’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph → Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Malic Acid

Interacts with 172 drugs

Malic acid is a natural acid found in apples and other fruits, often combined with magnesium in supplements marketed for fibromyalgia and muscle pain. The evidence for its health benefits is...

Read the full Malic Acid monograph → Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph →
Sources

Sources & How We Checked

Myo-Mag's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 154 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
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Manganese 21 references
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Vitamin B6 32 references
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Malic Acid 7 references
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Riboflavin 5 references
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See these in context on the Magnesium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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