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Dietary supplement

NADH 20 mg Ingredients & Drug Interactions

by NOW

NADH 20 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NADH 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

NADH 20 mg is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioenergy Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against NADH 20 mg by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with NADH 20 mg by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of NADH 20 mg by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients. NADH is a coenzyme form of vitamin B3 that plays a role in cellular energy production.

Bioenergy Ribose is a five-carbon sugar involved in energy metabolism and ATP synthesis — the molecule your cells use for fuel. The inactive ingredients are cellulose, cellulose powder, stearic acid, silica, magnesium stearate, and beeswax, which help form and preserve the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cellular energy production and mental alertness.
  • We looked for evidence on: Chronic fatigue syndrome (CFS), Athletic performance, Jet lag, Fibromyalgia, Cognitive function, Parkinson disease — and 3 related terms.
  • The strongest evidence on file: Nadh is rated "Possibly Effective" for Chronic fatigue syndrome (CFS) (Natural Medicines).
  • Also on file: Ribose is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Cognitive function, Fibromyalgia.

NADH is possibly effective for chronic fatigue syndrome based on the evidence we hold. For Parkinson disease, dementia, and alcohol-related liver disease, there isn't enough reliable evidence yet to say whether it helps.

Ribose is possibly ineffective for athletic performance and McArdle disease. For restless legs syndrome, muscle soreness, and heart surgery recovery, the evidence is too limited to rate either way.

The evidence, ingredient by ingredient Ribose Nadh

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated in the short term, though long-term safety data is limited. Ribose can cause diarrhea, nausea, gastrointestinal discomfort, headache, and — because it lowers blood sugar — hypoglycemia; some people have also reported anxiety, lightheadedness, and increased appetite, though lowering the dose resolved these in studies.

Neither ingredient has enough safety information for pregnancy or breastfeeding, so the safety data advises against use in both. If you're pregnant or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Ribose Nadh

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure and blood sugar medications — especially insulin and antidiabetes drugs — before you start this product, because ribose may increase the risk of low blood sugar (hypoglycemia) at a moderate level. No interactions are documented for NADH in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might help if you have chronic fatigue syndrome, though the evidence is still emerging. If you take insulin or a diabetes medication, you need to check your specific drugs with your pharmacist or doctor first — ribose can lower blood sugar.

Long-term safety isn't well established for either ingredient, so don't use it without talking it over with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NADH 20 mg, straight from the product label.

Brand NOW
Barcode (UPC) 733739031044
Net contents 30 Veg Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 14339
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NADH 20 mg by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
733739031044
IngredientAmount% DV
Bioenergy Ribose200 mg--
NADH20 mg--

Other ingredients: Cellulose, Cellulose powder, Stearic Acid, Silica, Magnesium Stearate, Beeswax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Caution: For adults only. Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Produced in a GMP facility that processes other ingredients containing these allergens.

Do Not Eat Freshness Packet. Keep in Bottle.

General Statements

Made in the USA

CELLULAR ENERGY PRODUCTION • Fights Fatigue • Supports Mental Alertness*

For more product information visit www.nowfoods.com/3104

Please Recycle.

NADH (Reduced Nicotinamide Adenine Dinucleotide), is the metabolically active form of Vitamin B3, also known as Niacin. NADH is essential for the production of cellular energy (ATP) from glucose and fat. Therefore, the more NADH a cell has available, the more energy it has available to operate with optimal efficiency. NADH is also directly involved in neurotransmitter production, the maintenance of genetic integrity, and the support of proper immune system function. Although NADH is normally unstable outside of the body, PANMOL(R) NADH uses a patented process to naturally preserve its effectiveness, thereby delivering stable and bioavailable NADH to the body.*

Seals/Symbols

PANMOL(R)

GMP QUALITY ASSURED

Formula

• With 200 mg D-Ribose

FDA Statement of Identity

A Dietary Supplement

Formulation

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Brand IP Statement(s)

PANMOL(R) is a registered trademark of Vis Vitalis GmbH.; Bioenergy RIBOSE(TM) is a trademark of Valen Labs, Inc. Use of ribose is licensed by Valen Labs, Inc. under U.S. Patents 6,159,942; 6,534,480; 6,218,366; 6,339,716, and other U.S. and foreign patents issued and pending.

Storage

Store in a cool, dry place after opening.

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 capsule daily on an empty stomach. Take with 8 oz. of water, 30 minutes before a meal.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

CODE 3104B V2

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NADH 20 mg by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NADH 20 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NADH 20 mg by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bioenergy Ribose

Interacts with
86 drugs
200 mg per serving Form: D-Ribose, Powder

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

Bioenergy Ribose monograph & interactions

NADH

No known
interactions
20 mg per serving Form: reduced Beta-Nicotinamide Adenine Dinucleotide

NADH is the active, electron-carrying form of niacin (vitamin B3) that your body uses to make energy in cells. Some people take it as a supplement for...

NADH monograph & interactions

Other (inactive) ingredients: Cellulose, Cellulose powder, Stearic Acid, Silica, Magnesium Stearate, Beeswax. These complete the product’s ingredient list but are not active constituents.

Interaction report

NADH 20 mg by NOW Drug Interactions

Want to check YOUR meds against NADH 20 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Bioenergy Ribose 86

Individual Drug Interactions

The ingredients in NADH 20 mg interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in NADH 20 mg interact with drugs. Each result below shows which ingredient is responsible. Bioenergy Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in NADH 20 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioenergy Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
Bioenergy Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for NADH 20 mg, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Pharmacist Counseling Corner

NADH 20 mg by NOW: Common Questions

Does NADH 20 mg by NOW interact with any medications?
Yes. Based on its ingredients, NADH 20 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NADH 20 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help with energy and fatigue?
NADH is possibly effective for chronic fatigue syndrome according to the evidence we hold. Ribose doesn't have enough reliable evidence to say it helps fatigue. If fatigue is your main reason for considering it, NADH is the ingredient with the stronger evidence, though even that's still emerging.
Can I take this if I have diabetes?
Not without checking first. Ribose can lower your blood sugar, and if you're on insulin or a diabetes medication, that combination could push your glucose too low. Talk with your doctor or pharmacist about your specific diabetes drugs before you start.
What side effects might I get?
Ribose may cause diarrhea, nausea, gastrointestinal discomfort, headache, or low blood sugar. Some people have also reported anxiety, lightheadedness, and increased appetite — lowering the dose resolved these in studies. NADH has no adverse effects documented in our data.
Is it safe to take this while pregnant or breastfeeding?
There isn't enough safety information for either ingredient during pregnancy or breastfeeding, so the safety data advises against it. Talk with your doctor or pharmacist for personalized advice before taking it.
How long can I take this safely?
Both ingredients are generally well tolerated short-term, but long-term safety data is limited. This isn't a supplement you should take indefinitely without checking in with your doctor or pharmacist about how long it's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NADH 20 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NADH 20 mg label
Go deeper

The Full Monographs Behind NADH 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph → Herb & supplement monograph

Nadh

NADH is the active, electron-carrying form of niacin (vitamin B3) that your body uses to make energy in cells. Some people take it as a supplement for fatigue, mental sharpness, and athletic...

Read the full Nadh monograph →
Sources

Sources & How We Checked

NADH 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Nadh 1 reference
  1. Niacin - Health Professional Fact Sheet — NIH Office of Dietary Supplements Source

See these in context on the Nadh monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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