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Dietary supplement

Organic Bhumiamalaki / Phyllanthus Amarus Ingredients & Drug Interactions

by Herbadiet

Organic Bhumiamalaki / Phyllanthus Amarus label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Bhumiamalaki / Phyllanthus Amarus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Bhumiamalaki / Phyllanthus Amarus is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for kidney stones, gallstones, liver support.Based on those ingredients, 1,020 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Bhumi Amalaki herb powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is pure organic Bhumi Amalaki herb powder — a single active ingredient, also known as chanca piedra. It contains no inactive fillers or other ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Chanca Piedra's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: liver detoxification and support.
  • We looked for evidence on: Hepatitis B, Nonalcoholic fatty liver disease (NAFLD), Gallbladder disease, liver function, hepatic health.
  • The closest evidence on file: Chanca Piedra is rated "Likely Ineffective" for Hepatitis B (Natural Medicines).
  • Also on file: Chanca Piedra is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Gallbladder disease.

The evidence best supports chanca piedra for kidney stones, where it's rated possibly effective. For other uses listed in the research — hepatitis B is rated likely ineffective, and the data on anemia of chronic disease and benign prostatic hyperplasia (enlarged prostate) are too thin to rate.

If kidney stones are what you're considering this for, the evidence suggests it may help; for other conditions, we don't have enough reliable data.

The evidence, ingredient by ingredient Chanca Piedra

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chanca piedra is generally well tolerated in the short term, but high-quality safety studies are limited. The most common side effects reported are abdominal pain, nausea, and vomiting.

One trial also noted fatigue in some people. The product should be avoided during pregnancy — there isn't enough safety information to know either way, and the data advises against it.

The same goes for breastfeeding; there isn't enough information, so talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Chanca Piedra

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chanca Piedra.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 1,021 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your doctor or pharmacist if you're on blood thinners (anticoagulants or antiplatelets like warfarin or aspirin), diuretics, lithium, blood pressure medications, diabetes medications, or any drugs metabolized through your liver. The bleeding risk with anticoagulants and the potential for lithium buildup are the most serious concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking at this for kidney stones, the evidence is moderately supportive. But chanca piedra interacts with a wide range of medications — blood thinners, blood pressure drugs, diuretics, lithium, and many drugs your liver processes — so it's critical to check your exact prescriptions before starting.

Talk it over with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Bhumiamalaki / Phyllanthus Amarus, straight from the product label.

Brand Herbadiet
Net contents 0 Not Present
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243604
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
4 Gram(s)
IngredientAmount% DV
organic Bhumi Amalaki herb powder2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Certified Organic Herb Powder

Liver Detoxifier

Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

V Vegan

Ethically Sourced Scientifically Tested Premium Grade Ingredients

Seals/Symbols

USDA Organic

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement take up to 4 gm, or as directed by your physician

Precautions

Keep out of reach of children.

Warning: Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Batch No. ARK-P95

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Bhumiamalaki / Phyllanthus Amarus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Amounts shown are per serving.

Organic Bhumi Amalaki herb powder

Interacts with
1,020 drugs
2 Gram(s) per serving

Chanca piedra is a tropical herb traditionally used as a 'stone breaker' for kidney and gallstones, and for liver and urinary health. Human evidence f...

Organic Bhumi Amalaki herb powder monograph & interactions
Interaction report

Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet Drug Interactions

Want to check YOUR meds against Organic Bhumiamalaki / Phyllanthus Amarus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,020Drugs
871 Moderate 149 Minor

Ingredients driving the most interactions

organic Bhumi Amalaki herb powder 1,020

Individual Drug Interactions

The ingredients in Organic Bhumiamalaki / Phyllanthus Amarus interact with 1,020 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Bhumiamalaki / Phyllanthus Amarus interact with drugs. Each result below shows which ingredient is responsible. organic Bhumi Amalaki herb powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Bhumiamalaki / Phyllanthus Amarus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Bhumi Amalaki herb powder8 drug types · 1,020 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In vitro research suggests that methyl brevifolincarboxylate, a constituent isolated from chanca piedra, can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that chanca piedra extract increases CYP1A2 activity. Theoretically, chanca piedra might increase metabolism of CYP1A2 substrates and lower serum concentrations. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that chanca piedra extract inhibits CYP3A4. Theoretically, chanca piedra might increase the levels of CYP3A4 substrates. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of chanca piedra with diuretics might increase diuresis.
Some preliminary clinical research in adults with hypertension shows that chanca piedra has diuretic properties. However, higher quality research in adults with kidney stones shows taking chanca piedra does not increase urine volume when compared with placebo. Until more is known, use cautiously in patients taking diuretic drugs.

Likelihood Possible Evidence D
Lithium

Theoretically, chanca piedra might reduce excretion and increase levels of lithium.
Some preliminary clinical research in adults with hypertension shows that chanca piedra has diuretic properties. However, higher quality research in adults with kidney stones shows that taking chanca piedra does not increase urine volume when compared with placebo. Until more is known, use cautiously in patients taking lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Norepinephrine (Levophed)

Theoretically, chanca piedra may reduce the effects of norepinephrine.
Animal research suggests that methyl brevifolincarboxylate, a constituent isolated from chanca piedra, can reverse blood vessel contraction caused by norepinephrine.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use with antidiabetes drugs might affect glucose control and increase the risk of hypoglycemia.
Animal research suggests that chanca piedra can have hypoglycemic effects. However, a small clinical study in adults with diabetes shows that chanca piedra extract 25 grams orally daily for 1 week does not lower fasting or postprandial blood glucose levels.

Likelihood Unlikely Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of chanca piedra with antihypertensive drugs might have additive blood pressure lowering effects.
Animal research suggests that chanca piedra can decrease blood pressure. However, this effect was not observed in most hypertensive patients treated with chanca piedra for 10 days.

Likelihood Unlikely Evidence D
organic Bhumi Amalaki herb powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Bhumiamalaki / Phyllanthus Amarus, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet: Common Questions

Does Organic Bhumiamalaki / Phyllanthus Amarus by Herbadiet interact with any medications?
Yes. Based on its ingredients, Organic Bhumiamalaki / Phyllanthus Amarus has a known interaction with 1,020 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Bhumiamalaki / Phyllanthus Amarus contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does chanca piedra actually work for kidney stones?
The evidence rates it possibly effective for kidney stones. Some clinical research supports it, though more study would be helpful. If you're considering it for this reason, talk with your doctor about whether it fits your situation.
What are the side effects?
The most common ones reported are abdominal pain, nausea, and vomiting. One trial also saw fatigue in some participants. Overall it's generally well tolerated, but long-term safety data are limited.
Can I take this while pregnant or breastfeeding?
No — the safety data advise against use during pregnancy. For breastfeeding, there isn't enough information to know either way, so you'll want to talk with your doctor or pharmacist about whether it's right for you.
Why does this interact with so many medications?
Chanca piedra affects how your body processes drugs through your liver enzymes and can act like a water pill. It also theoretically affects blood clotting and blood pressure. These are broad systems, so the ripple touches many different drug classes.
Is this ingredient the same as what's on the label?
Yes — Bhumi Amalaki and Phyllanthus Amarus (the scientific name) are the same plant, also called chanca piedra. It's a single-ingredient herb powder with no fillers added.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Bhumiamalaki / Phyllanthus Amarus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Bhumiamalaki / Phyllanthus Amarus label
Go deeper

The Full Monographs Behind Organic Bhumiamalaki / Phyllanthus Amarus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chanca Piedra

Interacts with 1,020 drugs

Chanca piedra is a tropical herb traditionally used as a 'stone breaker' for kidney and gallstones, and for liver and urinary health. Human evidence for these uses is limited and mostly smal...

Read the full Chanca Piedra monograph →
Sources

Sources & How We Checked

Organic Bhumiamalaki / Phyllanthus Amarus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chanca Piedra 18 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Indian J Exp Biol 1995; 33:861-4.
  3. Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Phytother.Res 2001;15(3):265-267.
  4. Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. B. The effect of Phyllanthus amarus aqueous extract on blood glucose in non-insulin dependent diabetic patients. Phytother.Res 2001;15(7):577-580.
  5. Nishiura, J. L., Campos, A. H., Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. Urol.Res 2004;32(5):362-366. PubMed
  6. Iizuka, T., Moriyama, H., and Nagai, M. Vasorelaxant effects of methyl brevifolincarboxylate from the leaves of Phyllanthus niruri. Biol.Pharm.Bull. 2006;29(1):177-179. PubMed
  7. Adeneye, A. A., Amole, O. O., and Adeneye, A. K. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice. Fitoterapia 2006;77(7-8):511-514. PubMed
  8. Iizuka, T., Nagai, M., Taniguchi, A., Moriyama, H., and Hoshi, K. Inhibitory effects of methyl brevifolincarboxylate isolated from Phyllanthus niruri L. on platelet aggregation. Biol.Pharm.Bull. 2007;30(2):382-384. PubMed
  9. Amaechina, F. C. and Omogbai, E. K. Hypotensive effect of aqueous extract of the leaves of Phyllanthus amarus Schum and Thonn (Euphorbiaceae). Acta Pol.Pharm. 2007;64(6):547-552.
  10. Okoli, C. O., Obidike, I. C., Ezike, A. C., Akah, P. A., and Salawu, O. A. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharm.Biol. 2011;49(3):248-255.
  11. Moshi MJ, Uiso FC Mahunnah RL et al. A study of the effect of Phyllanthus amarus extracts on blood glucose in rabbits. International Journal of Pharmacognosy 1997;35(3):167-173. DOI
  12. Kumar NG, Nair AN Raghunandanan VR et al. Hypoglycaemic effect of Phyllanthus niruri leaves in rabbits. Kerala Journal of Veterinary Science 1989;20(1):77-80.
  13. Navarro M, Coussio J Hnatyszyn O et al. Hypoglycemic Effect of an Aqueous Extract of Phyllanthus sellowianus ("sarandi blanco") in C57BL/Ks mice. Acta Farmaceutica Bonaerense 2004;23:520-523.
  14. Etta HE, Udoh PB Asuquo BO et al. Effect of Phyllanthus amarus on breeding efficiency of female albino rats. Global Journal of Agricultural Sciences 2007;215-217. DOI
  15. Etta H. Effects of Phyllanthus amarus on litter traits in albino rats. Scientific Research and Essays 2008;370-372.
  16. Pucci ND, Marchini GS, Mazzucchi E, et al. Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. Int Braz J Urol 2018;44(4):758-64. PubMed
  17. Sowjanya K, Girish C, Bammigatti C, Prasanna Lakshmi NC. Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial. Indian J Pharmacol 2021;53(6):448-456. PubMed
  18. Husain I, Abdulrahman B, Dale OR, et al. Interaction of Phyllanthus amarus extract and its lignans with human xenobiotic receptors, drug metabolizing enzymes and drug transporters. J Ethnopharmacol 2025;339:119142. PubMed

See these in context on the Chanca Piedra monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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