Interactions on record — worth a quick check against your medications. Based on 4 of 9 ingredients. Check your meds →
Dietary supplement

Organic Longevity Mushrooms Chocolate Fudge Syrup Ingredients & Drug Interactions

by Cymbiotika

Organic Longevity Mushrooms Chocolate Fudge Syrup label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Longevity Mushrooms Chocolate Fudge Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Longevity Mushrooms Chocolate Fudge Syrup is a dietary supplement by Cymbiotika with 9 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 552 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mushroom powder, King Trumpet Mushroom powder, Maitake Mushroom Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 8 of its 9 active ingredients.
  • “organic Mushroom powders” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains 9 active ingredients — four medicinal mushroom powders (reishi, maitake, king trumpet, and turkey tail), plus antrodia mushroom powder, EGCG (a green tea compound), and three fat components (polyunsaturated, monounsaturated, and cholesterol fat). The inactive ingredients are organic sunflower lecithin, organic coconut glycerin, organic sprouted almond butter, mushroom mycelium and fruiting bodies, Himalayan sea salt, organic green tea extract, organic vitamin E, organic vanilla extract, and organic cacao extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Immune support, gut health, stress management.
  • We looked for evidence on: Stress, Psychological well-being, Immune function, Digestive health, Liver function.
  • The closest evidence on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Stress (Natural Medicines).
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Psychological well-being.

For the mushroom ingredients we have data on, the evidence is mixed or sparse. Turkey tail mushroom is possibly effective for cancer support.

Reishi mushroom did not prove effective for high cholesterol (hyperlipidemia) in the studies we hold. The rest — including maitake, king trumpet, and reishi — lack enough reliable evidence to establish whether they work for the conditions they're marketed for, including fatigue, cognitive function, and immune support.

We don't have effectiveness data for antrodia mushroom powder or EGCG in this product's context.

The evidence, ingredient by ingredient Reishi Mushroom Maitake Mushroom Lion's Mane Mushroom Turkey Tail Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The mushroom ingredients are generally well tolerated short-term when taken by mouth. Common side effects reported in trials include gastrointestinal upset (nausea, diarrhea, stomach discomfort), dizziness, dry mouth, rash, and itching — a small number of trial participants experienced these.

Reishi mushroom may rarely cause insomnia or headache. Respiratory allergy to reishi spores is possible, with sore throat and runny nose reported.

During pregnancy, there isn't enough safety data for any of these mushroom concentrates, so they're best avoided — talk with your doctor or pharmacist for personalized guidance. The same holds for breastfeeding.

Long-term safety is not well studied for these ingredients.

Side effects, ingredient by ingredient Reishi Mushroom Maitake Mushroom Lion's Mane Mushroom Turkey Tail Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Maitake Mushroom, Turkey Tail Mushroom, Reishi Mushroom, Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 552 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate bleeding risk), blood pressure medications (moderate risk of low blood pressure), diabetes medications (moderate risk of low blood sugar), chemotherapy drugs like cyclophosphamide or tamoxifen, or any drug metabolized by the liver enzyme CYP2C9. No interactions are documented for the three fat components or antrodia mushroom powder — we simply lack data for them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, blood pressure medications, diabetes medications, or chemotherapy drugs, talk with your doctor or pharmacist before using this product. The mushroom blend is generally well tolerated for short periods, though gastrointestinal upset and dizziness can occur.

Pregnant or breastfeeding — skip it and check with your own healthcare provider about your individual situation. For everyone else, use the medication checker on this page to confirm your exact drugs won't interact.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Longevity Mushrooms Chocolate Fudge Syrup, straight from the product label.

Brand Cymbiotika
Net contents 16 Fluid Ounce(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 253134
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 mL
Maximum serving Sizes:
15 mL
Servings per container
30
IngredientAmount% DV
Calories73 Calorie(s)--
Total Carbohydrates7 Gram(s)2%
Sugar0 Gram(s)--
Calories from Fat45 Calorie(s)--
Protein0 Gram(s)--
Total Fat5 Gram(s)8%
Polyunsaturated Fat1 Gram(s)--
Monounsaturated Fat4 Gram(s)--
Saturated Fat0 Gram(s)--
Cholesterol Fat0 mg--
Reishi Mushroom powder50 mg--
Maitake Mushroom Powder50 mg--
King Trumpet Mushroom powder50 mg--
Turkey Tail Mushroom powder50 mg--
organic Mushroom powders0 NP--
Antrodia Mushroom powder50 mg--
EGCG50 mg--

Other ingredients: organic Sunflower Lecithin, organic Coconut Glycerin, organic sprouted Almond Butter, organic Mushroom Mycelium and Fruiting bodies, Himalayan Sea Salt, organic Green Tea extract, organic Vitamin E, organic Vanilla extract, organic Cacao extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use 1 tbsp daily Squeeze onto a tablespoon & consume or mix into cool or hot beverage for a delicious chocolate additin. Drizzle over your favorite ice cream, yogurt, fruit or dessert.

Storage

Store in the refrigerator for maximum freshness.

Formulation

Promotes Enhanced viral defense Supports gut health Immune & liver support Manage stress

Cymbiotika formulates products with only the highest quality, bioavailable organic and wild crafted ingredients.

This product contains zero chemicals, animal products, GMOs, soy, wheat, gluten, corn, dairy, lactose, eggs, yeast, sugar, solvents, fillers, binders, flavors, additives, coloring, fragrance, silicon or BPA.

Organic

Vegan

Sugar free

Beauty Immunity Balance Micelle liposomal Grown in the USA

FDA Disclaimer Statement

These statemnets have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Consult your healthcare professional before taking any dietary supplements.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Longevity Mushrooms Chocolate Fudge Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Protein

0 Gram(s) per serving

Cholesterol Fat

0 mg per serving

Organic Mushroom powders

0 NP per serving

EGCG

50 mg per serving Form: Green Tea extract

Other (inactive) ingredients: Organic Sunflower Lecithin, Organic Coconut Glycerin, Organic sprouted Almond Butter, Organic Mushroom Mycelium and Fruiting bodies, Himalayan Sea Salt, Organic Green Tea extract, Organic Vitamin E, Organic Vanilla extract, Organic Cacao extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika Drug Interactions

Want to check YOUR meds against Organic Longevity Mushrooms Chocolate Fudge Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
552Drugs
495 Moderate 57 Minor

Ingredients driving the most interactions

Reishi Mushroom powder 375
King Trumpet Mushroom powder 327
Maitake Mushroom Powder 260
Turkey Tail Mushroom powder 187

Individual Drug Interactions

The ingredients in Organic Longevity Mushrooms Chocolate Fudge Syrup interact with 552 drugs. Click any drug to see the details.

4 of the 9 ingredients in Organic Longevity Mushrooms Chocolate Fudge Syrup interact with drugs. Each result below shows which ingredient is responsible. Reishi Mushroom powder King Trumpet Mushroom powder Maitake Mushroom Powder Turkey Tail Mushroom powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Longevity Mushrooms Chocolate Fudge Syrup with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Mushroom powder3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Mushroom powder full monograph & interactions

King Trumpet Mushroom powder3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
King Trumpet Mushroom powder full monograph & interactions

Maitake Mushroom Powder3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
Maitake Mushroom Powder full monograph & interactions

Turkey Tail Mushroom powder4 drug types · 187 drugs

Antidiabetes Drugs

Theoretically, taking turkey tail mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that turkey tail mushroom and a polysaccharide component can have hypoglycemic effects.

Likelihood Possible Evidence D
Cyclophosphamide

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might increase exposure to cyclophosphamide.
Some animal research shows that the PSP component of turkey tail mushroom can increase the area under the concentration-time curve (AUC) of cyclophosphamide by 44% to 50% and the half-life by 34% to 43%. This interaction could potentially increase the effects and adverse effects of cyclophosphamide. However, it is not known whether PSP affects the levels of the active metabolites of cyclophosphamide that are responsible for its clinical activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might interfere with the absorption of tamoxifen.
Animal research suggests that PSP increases the time to reach maximum concentration of a single dose of tamoxifen by about 9.5 hours, or 228%. When repeated doses of tamoxifen were given, the time to reach maximum concentration was increased by about 5.6 hours, or 93%. However, PSP did not affect the maximum concentration or the area under the curve of tamoxifen.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might inhibit CYP2C9.
Laboratory research suggests that the PSP component of turkey tail mushroom dose-dependently inhibits CYP2C9. Theoretically, taking PSP with drugs metabolized by CYP2C9 might increase drug levels and the risk of adverse effects. However, this has not been reported in humans.

Likelihood Possible Evidence D
Turkey Tail Mushroom powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Longevity Mushrooms Chocolate Fudge Syrup, from the product label.

Cymbiotika

See all Cymbiotika products
Name
Cymbiotika
Pharmacist Counseling Corner

Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika: Common Questions

Does Organic Longevity Mushrooms Chocolate Fudge Syrup by Cymbiotika interact with any medications?
Yes. Based on its ingredients, Organic Longevity Mushrooms Chocolate Fudge Syrup has a known interaction with 552 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Longevity Mushrooms Chocolate Fudge Syrup contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The safety data available for these mushroom concentrates isn't enough to say it's okay. The facts advise against it during pregnancy and breastfeeding. Talk with your doctor or pharmacist — they know your situation and can give you personalized advice.
What side effects might I notice?
Most commonly, people report gastrointestinal upset like nausea or diarrhea, dizziness, dry mouth, rash, or itching. Reishi mushroom may rarely cause insomnia or headache. A small number of trial participants had these, so they're not common, but they do happen.
Is it safe to use long-term?
Long-term safety for these mushroom ingredients isn't well studied. The data we hold covers short-term use only. If you're thinking of taking it regularly for months, check in with your doctor or pharmacist first.
What is king trumpet mushroom actually supposed to do?
In our data, we don't have enough reliable evidence to say what king trumpet mushroom does for any specific condition. It's included in this blend, but the research backing its effects isn't established yet.
Does this product help with cancer?
Turkey tail mushroom in this blend is rated possibly effective for cancer support — that's the strongest evidence we hold for any ingredient. The other mushrooms don't have established evidence for cancer or most other conditions.
Can I take this with my warfarin (blood thinner)?
Not without checking first. There's a case report of a patient on warfarin who developed an elevated clotting time after taking a maitake mushroom supplement, and this product contains maitake. Talk with your doctor or pharmacist before combining them — they can decide if it's safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Longevity Mushrooms Chocolate Fudge Syrup is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Longevity Mushrooms Chocolate Fudge Syrup label
Go deeper

The Full Monographs Behind Organic Longevity Mushrooms Chocolate Fudge Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph → Herb & supplement monograph

Turkey Tail Mushroom

Interacts with 187 drugs

Turkey tail is a woodland mushroom rich in polysaccharides like beta-glucans, and it is mainly used to support the immune system. Some of its purified extracts (PSK and PSP) have been studie...

Read the full Turkey Tail Mushroom monograph →
Sources

Sources & How We Checked

Organic Longevity Mushrooms Chocolate Fudge Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 46 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

See these in context on the Maitake Mushroom monograph →

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
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Turkey Tail Mushroom 15 references
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  7. Imaizumi, M., Kondo, T., Kamei, H., and Ichihashi, H. [Cooperative studies on surgical adjuvant immunochemotherapy for prevention of postoperative recurrence of gastric cancer]. Gan To Kagaku Ryoho 1984;11(1):60-68.
  8. Yeung JH and Or PM. Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes. Phytomedicine 2011;18(13):1170-5. PubMed
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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