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Dietary supplement

Organic Mucuna Ingredients & Drug Interactions

by Herbadiet

Organic Mucuna label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Mucuna against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Organic Mucuna is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for parkinson's disease symptoms, male fertility and libido, mood and stress support.Based on those ingredients, 193 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Mucuna, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Mucuna by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Mucuna by Herbadiet — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Organic Mucuna by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Herbadiet's Organic Mucuna Powder contains one active ingredient: mucuna powder, also called cowhage, a legume whose seeds are a natural source of levodopa — the same compound used in Parkinson's disease medications. This product contains no inactive fillers or other ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cowhage's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Natural mood enhancer.
  • We looked for evidence on: Anxiety, Depression, Stress, Emotional balance.
  • The closest evidence on file: Cowhage is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).

We hold no established effectiveness ratings for mucuna in the conditions listed in our data — anxiety, skin inflammation, high prolactin levels, muscle pain, Parkinson's disease, or rheumatoid arthritis — meaning the evidence we have is insufficient to rate how well it works for any of them. If you're considering this product for a specific purpose, that's something to discuss with your doctor or pharmacist.

The evidence, ingredient by ingredient Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mucuna is generally well tolerated when taken by mouth, though a thorough safety evaluation hasn't been done. The most commonly reported side effects are digestive — diarrhea, flatulence, and mucosal irritation.

Some people report dry mouth, nausea, belly bloating, vomiting, headaches, and insomnia; in one clinical trial using specific doses of 22.5 to 67.5 grams per day split across multiple doses, about 3% of participants experienced insomnia. The safety data advises against use during pregnancy because there isn't enough information and mucuna's dopamine effects raise concerns.

Similarly, L-dopa can lower prolactin levels and may reduce milk supply, so the data advises against use while breastfeeding. Because mucuna contains a potent, drug-like compound, use it only with professional guidance.

Side effects, ingredient by ingredient Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 193 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take monoamine oxidase inhibitors (MAOIs) for depression — the risk of dangerously high blood pressure is serious. Also double-check methyldopa or guanethidine (blood pressure drugs), levodopa (Parkinson's medication), blood sugar medications, antipsychotics, tricyclic antidepressants, or if you'll be undergoing surgery with certain anesthetics.

Use the medication search tool on this page to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Mucuna is best for people exploring its traditional or researched uses who don't take MAOIs, methyldopa, guanethidine, or other medications that interact with levodopa, and who are not pregnant or breastfeeding. If you take any prescription medication — especially for blood pressure, depression, Parkinson's disease, blood sugar control, or mental health — run your full medication list through the interaction checker on this page before you start.

Your pharmacist can help you decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Mucuna, straight from the product label.

Brand Herbadiet
Net contents N/A
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 313684
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Mucuna by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2000 mg
Maximum serving Sizes:
4000 mg
IngredientAmount% DV
Mucuna, Powder2000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Natural mood enhancer

Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

Vegan

Ethically sourced Scientifically tested

Premium grade ingredients

USDA Organic

Formula

Certified organic herb powder

Seals/Symbols

USDA Organic

Vegan

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take up to 4000mg daily, or as directed by physician.

Precautions

Keep out of reach of children.

Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

Best before 2 years from the date of Mfg.

FDA Disclaimer Statement

Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Mucuna by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Mucuna label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Mucuna by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2000 mg Dosage formPowder Amounts shown are per serving.

Mucuna, Powder

Interacts with
193 drugs
2000 mg per serving Form: Mucuna pruriens powder

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna, Powder monograph & interactions
Interaction report

Organic Mucuna by Herbadiet Drug Interactions

Want to check YOUR meds against Organic Mucuna?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
193Drugs
17 Major 176 Moderate

Ingredients driving the most interactions

Mucuna, Powder 193

Individual Drug Interactions

The ingredients in Organic Mucuna interact with 193 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Mucuna interact with drugs. Each result below shows which ingredient is responsible. Mucuna, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Mucuna with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mucuna, Powder8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Mucuna, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Organic Mucuna by Herbadiet: Common Questions

Does Organic Mucuna by Herbadiet interact with any medications?
Yes. Based on its ingredients, Organic Mucuna has a known interaction with 193 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Mucuna contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is mucuna and where does it come from?
Mucuna, also called cowhage, is a legume plant whose seeds naturally contain levodopa — the same compound used in Parkinson's disease medications. This powder is made from those seeds.
What side effects might I experience?
Most common are digestive issues like diarrhea, flatulence, and stomach irritation. Some people report dry mouth, nausea, belly bloating, vomiting, headaches, or trouble sleeping. A thorough safety study hasn't been completed, so other effects may occur.
Is it safe to take while pregnant or breastfeeding?
The safety data advises against both. During pregnancy, there isn't enough information and mucuna's dopamine effects raise concerns. While breastfeeding, levodopa can lower prolactin and reduce milk supply.
Will this product work for Parkinson's disease?
We don't have enough evidence to rate how well mucuna works for Parkinson's disease. Because it contains levodopa, it's similar to prescription Parkinson's medications but should only be used under professional guidance.
Why is this product so dangerous with certain medications?
Mucuna contains levodopa, an active drug-like compound that works in your brain and body. When it mixes with certain medications — especially blood pressure drugs or antidepressants — it can cause serious effects like dangerously high or low blood pressure or abnormal heart rhythms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Mucuna is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Mucuna label
Go deeper

The Full Monographs Behind Organic Mucuna’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Organic Mucuna's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cowhage 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
  4. HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
  5. Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
  6. Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
  7. Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
  8. Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
  9. Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
  10. Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
  11. Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
  12. Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed

See these in context on the Cowhage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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