Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Power Carb Unflavored Flavor Ingredients & Drug Interactions

by Labrada Nutrition

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Power Carb Unflavored Flavor is a dietary supplement by Labrada Nutrition with 5 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,035 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Power Carb Unflavored Flavor by Labrada Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.

Power Carb Unflavored Flavor contains two active ingredients: sodium and potassium. These are electrolytes — minerals your body needs to keep your heart beating, muscles contracting, and fluids balanced.

The product contains one inactive ingredient, Power Carb (Karbo-Lyn).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: athletic performance and muscle glycogen loading.
  • We looked for evidence on: Exercise performance, Athletic endurance, Muscle energy metabolism.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness data for potassium in this product. For sodium, the evidence shows it's likely effective for cystic fibrosis and possibly effective for reducing kidney damage from amphotericin B (an antifungal drug).

The evidence isn't established for bipolar disorder or heart failure in our data.

The evidence, ingredient by ingredient Black Psyllium Sodium Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated in the amounts you'd normally eat, but too much — especially from supplements — is linked to high blood pressure, heart strain, and kidney problems. Potassium from food is safe, but potassium supplements can cause dangerously high blood levels in some people, especially those with kidney disease.

The facts show sodium has conflicting pregnancy and lactation safety data — one entry rates it likely safe, another possibly unsafe — so talk with your doctor or pharmacist before using this during pregnancy or breastfeeding. Potassium is rated likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Black Psyllium Sodium Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Black Psyllium, Potassium, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,036 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before using this if you take blood pressure medications (especially ACE inhibitors, ARBs, or potassium-sparing diuretics), lithium, corticosteroids, water pills, any HIV medications like didanosine, or any other sodium-containing drugs — all are Moderate severity interactions. Your doctor or pharmacist can tell you whether it's okay to use it alongside your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a source of two electrolytes that need careful handling if you take medications for blood pressure, heart rhythm, kidney disease, or bipolar disorder. If you're on any prescription medication, check with your doctor or pharmacist before adding this supplement — sodium and potassium can change how several drugs work and can cause serious imbalances in your blood.

If you have kidney disease, talk it over first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Power Carb Unflavored Flavor, straight from the product label.

Brand Labrada Nutrition
Barcode (UPC) 710779112810
Net contents 2.2 lbs; 998 Gram(s)
Market status On market
Date entered into DSLD May 23, 2014
DSLD ID 32926
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Power Carb Unflavored Flavor by Labrada Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Gram(s)
Maximum serving Sizes:
50 Gram(s)
Servings per container
40
UPC/BARCODE
710779112810
IngredientAmount% DV
Calories100 NP--
Total Carbohydrates25 Gram(s)10%
Sugar0 Gram(s)--
Calories from Fat0 NP--
Dietary Fiber0 Gram(s)--
Protein0 Gram(s)--
Saturated Fat0 Gram(s)--
Sodium0 mg--
Trans Fat0 Gram(s)--
Potassium0 mg--
Cholesterol0 mg--
Total Fat0 Gram(s)--

Other ingredients: Power Carb(TM) (Karbo-Lyn(R)

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent and disease.

Formulation

Power Carb(TM) is a SUGAR-FREE and completely instant, and easily digestible! It is absorbed very quickly with out stomach bloating or discomfort.

SUGAR-FREE

General Statements

PERFORMANCE ENHANCER* WORKS WITH 1ST DOSE!* Absorbed 1200% FASTER than Other Carbs*

Current Good Manufacturing Practices

Hi-Performance Carbohyrate "Superfood"

Increases Supplement Uptake

Brand IP Statement(s)

Power Carb(TM) is made in a steroid and prohormone free, FDA-inspected pharmaceutical-grade manufacturing facility. This product is pure and unadulterated, and will not cause a positive test result for banned substances, making it perfect for high school, college, Olympic and professional athletes who want to naturally boost their athletic performance.

POWER CARB(TM) Rapid Muscle Glycogen SuperLoader(TM)

What is Power Carb(TM)? Power Carb(TM) is Labrada Nutrition's Designer Carb(TM), a functional carbohydrate "superfood" engineered to rapidly replenish muscle glycogen, increase nutrient uptake, and enhance muscular function. Power Carb(TM) is a nutritional breakthrough that will forever change the way you fuel your muscles. You'll never suffer through a bad workout or flat athletic performance again! What Can Power Carb(TM) Do For Me? Power Carb(TM) can massively increase glycogen stores inside your muscles up to 1200% faster than pasta, rice, or bread. It literally forces glycogen storage, resulting in a huge increase in energy and the ability to exercise harder and longer. And because every gram of glycogen pushed into muscles pulls in 4 grams of water, you can expect your muscles to fully hydrate, with your skin pulled tightly around them, resulting in a more muscular appearance, starting WITH THE FIRST DOSE! How Does Power Carb(TM) Work? Power Carb(TM) is a homopolysaccharide (homogenous, relatively-complex carbohydrate) made up of thousands of monosaccharides (sugar molecules) joined together by glycosidic bonds to form branched macromolecules (large molecules.) The molecular mass (molecule size and weight) of Power Carb(TM) has been engineered to enhance gastric transit through the stomach at a rate much greater than common carbohydrates such as waxy maize, maltodextrins, breads. pasta or rice. Power Carb(TM) is produced from natural complex carbohydrate sources using a newly-developed, patent pending "Enzymatic Milling Process."

Karbo-Lyn(R) is a registered trademark of All American Pharmaceutical.

How Does Power Carb(TM) Increase My Supplement Uptake? Power Carb(TM) increases the effectiveness of any other supplement you take with it. Because Power Carb(TM) passes through the stomach very quickly, it acts like a pump, pulling water and nutrients along with it, which are then shuttled into muscle cells. Nutrient uptake is increased so you get more out of your supplements. Take Power Carb (TM) along with your creatine, BCAA's beta-alanine or other supplements to "express shuttle" them into to your muscles. Is Power Carb(TM) Right for Me? Power Carb(TM) is a powerful performance tool for all athletes including fitness enthusiasts, runners, bicyclists, ball players, tri-athletes, and body builders.

(C) LBN, Inc,

Rapid Muscle Glycogen SuperLoader(TM)

Suggested/Recommended/Usage/Directions

Directions: Training Days- Pre-Workout: Mix 1 to 2 scoops pf Power Carb(TM) in 20 oz. of water and consume 45-60 minutes prior to physical activity. Combine with your pre-and during workout supplement to massively increase their absorption rate. For an extraordinary training experience, stack Power Carb(TM) with Labrada's Super Charge!(R) Xtreme Pre-Workout Drink. Yo may sip Power Carb(TM) during your workout to sustain intensity and muscular energy. Post-Workout- mix 1 to 2 scoops of Power Carb(TM) in 20 oz. of water, and consume immediatley after your workout. You may add amino acids, BCAA's, creatine, or protein powder to rapidly increase their uptake and jump start glycogen replenishment and muscle issue repair and recovery. Non-Training Days- Mix 1 serving of Power Carb(TM) with your favorite protein powder such as Lean Pro8(R) or ProV60(R) to make a great meal replacement shake! Power Carb(TM) will help you with recovery on your days of by optimizing nutrient uptake to ensure muscle recovery and growth.

How Should I use Power Carb(TM)? Use Power Carb(TM) before, during and right after training to boost energy, prevent the onset of fatigue, and then jumpstart the glycogen recharging process to shorten your post workout recovery time. Power Carb(TM) works equally well, whether you are a strength or endurance athlete! Power Carb(TM) is excellent for athletes who have multiple training sessions per day-use it to rapidly increase muscle glycogen, decrease recovery time and increase energy for your for an extra 1-2 hours. Mix Power Carb(TM) with a high quality protein powder such as Lean Pro(R) or Lean Body(R) to increase protein uptake after your workout.

Formula

Calories 2,000 2,500 Total Fat 65g 80g Saturated Fat 20g 25g Cholesterol 300mg 300mg Sodium 2,400mg 2,400mg Potassium 3,500mg 3,500mg Total Carbohydrates 300g 375g Dietary Fiber 25g 30g Calories per gram: Fat 9 Carbohydrates 4 Protein 4

Precautions

If you are diabetic, consult your physician before using Power Carb(TM)

WARNING: Due to extremely fast uptake of Power Carb(TM), it is important to drink plenty of water to maximize its effects. Consume at least 20 ounces of cold water with each serving. Beneficial "muscle fullness" is common, starting with the first dose.

Seals/Symbols

NO BANNED SUBSTANCES STEROID-FREE CERTIFIED cGMP(TM)

See for yourself

Power Carb Unflavored Flavor by Labrada Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Power Carb Unflavored Flavor by Labrada Nutrition

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Gram(s) Dosage formPowder Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
0 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

0 Gram(s) per serving

Sodium

Interacts with
205 drugs
0 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
0 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Power Carb(TM) (Karbo-Lyn(R). These complete the product’s ingredient list but are not active constituents.

Interaction report

Power Carb Unflavored Flavor by Labrada Nutrition Drug Interactions

Want to check YOUR meds against Power Carb Unflavored Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,035Drugs
242 Moderate 1,793 Minor

Ingredients driving the most interactions

Sodium 205

Each ingredient & the kinds of drugs it affects

For each ingredient in Power Carb Unflavored Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Power Carb Unflavored Flavor, from the product label.

Labrada Nutrition

See all Labrada Nutrition products
Name
Labrada Nutrition
Street Address
333 Northpark Central Dr.
City
Houston
State
TX
ZipCode
77073
Web Address
www.labrada.com
Pharmacist Counseling Corner

Power Carb Unflavored Flavor by Labrada Nutrition: Common Questions

Does Power Carb Unflavored Flavor by Labrada Nutrition interact with any medications?
Yes. Based on its ingredients, Power Carb Unflavored Flavor has a known interaction with 2,035 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Power Carb Unflavored Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this product safe during pregnancy?
The data shows conflicting safety ratings for sodium — one says likely safe, another says possibly unsafe — and we don't have enough information to give you a clear answer. Potassium rates as likely safe. Talk with your doctor or pharmacist before using this while pregnant; they can weigh the ingredients against your individual needs.
What are the side effects of potassium from this product?
Potassium is generally well tolerated when you eat it from food, but supplements can cause abdominal pain, belching, diarrhea, nausea, and vomiting. In rare cases, high potassium levels can cause irregular heartbeat, low blood pressure, and mental confusion — which is why it matters to check with your doctor first if you're on certain medications.
Can I take this if I have kidney disease?
No — talk with your doctor or pharmacist first. Sodium and potassium supplements can be risky if your kidneys don't filter electrolytes normally. This is something you need personalized advice on from your own healthcare provider.
Will this raise my blood pressure?
If you take a lot of sodium and you're sensitive to it, yes — high sodium intake is linked to higher blood pressure. If you're already on blood pressure medication, extra sodium can make that medication work less well. Your doctor can advise whether this product fits your situation.
Is it safe to take this with my water pill (diuretic)?
It depends on the type of water pill. Some water pills interact with potassium at Moderate severity and raise the risk of dangerously high potassium levels. Check with your doctor or pharmacist about your specific medication before adding this product.
What is this product meant to do?
Power Carb is a carbohydrate powder — the sodium and potassium in it serve as electrolytes to help with hydration and fluid balance during or after exercise. The effectiveness data we hold shows sodium is likely effective for cystic fibrosis and possibly effective for certain kidney damage, but those aren't the uses this product markets.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Power Carb Unflavored Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Power Carb Unflavored Flavor label
Sources

Sources & How We Checked

Power Carb Unflavored Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 68 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
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Potassium 12 references
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See these in context on the Potassium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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