Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pro-Copper S.O.D. Mimetic Ligand Ingredients & Drug Interactions

by Ecological Formulas

Pro-Copper S.O.D. Mimetic Ligand label
See full label image
Capsule Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pro-Copper S.O.D. Mimetic Ligand against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pro-Copper S.O.D. Mimetic Ligand is a dietary supplement by Ecological Formulas with 1 active ingredient. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 31 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: copper. Copper is an essential mineral your body needs for bone health, immune function, and iron metabolism.

The inactive ingredients are cellulose, gelatin, magnesium stearate, glutathione, and silicon dioxide.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Copper supplementation and antioxidant defense.
  • We looked for evidence on: Copper deficiency, Immune function, Connective tissue health, Red blood cell formation.
  • The strongest evidence on file: Copper is rated "Likely Effective" for Copper deficiency (Natural Medicines).

Copper is likely effective for treating copper deficiency — which matters if you've been diagnosed with low copper levels. For Alzheimer disease, the evidence suggests it may be ineffective.

For acne, chemotherapy-induced anemia, and brain tumors, we don't have enough reliable evidence to know whether copper helps or doesn't.

The evidence, ingredient by ingredient Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper from food and standard supplement doses is generally well tolerated. However, excess copper can be toxic, so stay within recommended amounts.

A rare side effect is contact dermatitis — direct skin irritation from copper contact has been reported in a small number of people. There's also evidence that people with diabetes tend to have higher blood copper levels than those without diabetes, though it's unclear whether elevated copper contributes to diabetes developing or getting worse.

Copper is needed in pregnancy, but stick to recommended amounts and avoid high-dose supplements without medical guidance.

Side effects, ingredient by ingredient Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 31 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you're on penicillamine — you'll need to dose copper at least 2 hours away from it to avoid reducing the drug's absorption. Also flag your birth control pills, since long-term copper use may raise your copper levels higher than normal when combined with hormonal contraceptives.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product makes sense if you've been diagnosed with copper deficiency and your doctor or pharmacist has recommended supplementation. If you take penicillamine or birth control pills, talk with your pharmacist before starting — the spacing or interaction risk matters.

Anyone with diabetes should also check in before use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pro-Copper S.O.D. Mimetic Ligand, straight from the product label.

Brand Ecological Formulas
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22922
Product type Mineral
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
IngredientAmount% DV
Copper4 mg200%

Other ingredients: Cellulose, Gelatin, Magnesium Stearate, Glutathione, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

10120074

FDA Statement of Identity

Dietary Supplement

A DIETARY SUPPLEMENT

General Statements

EXP1212

PRO-COPPER LIGAND is a scientifically-designed dietary supplement containing an equimolar complex of copper and sebacic acid, which yields 4mg of elemental copper. Sebacic acid and reduced glutathione protect the cuprous form of copper against oxidation and facilitate passage through cell membranes.

Suggested/Recommended/Usage/Directions

DIRECTIONS Take one or two capsules daily, or as directed by a physician.

FDA Disclaimer Statement

This product has not been evaluated by the FDA. This product is not intended to diagnose, cure, treat or prevent any disease.

Seals/Symbols

ECOLOGICAL FORMULAS

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pro-Copper S.O.D. Mimetic Ligand label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Copper

Interacts with
31 drugs
4 mg per serving Form: Copper Sebacate

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Other (inactive) ingredients: Cellulose, Gelatin, Magnesium Stearate, Glutathione, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas Drug Interactions

Want to check YOUR meds against Pro-Copper S.O.D. Mimetic Ligand?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
31Drugs
1 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Individual Drug Interactions

The ingredients in Pro-Copper S.O.D. Mimetic Ligand interact with 31 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pro-Copper S.O.D. Mimetic Ligand interact with drugs. Each result below shows which ingredient is responsible. Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Pro-Copper S.O.D. Mimetic Ligand with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pro-Copper S.O.D. Mimetic Ligand, from the product label.

Ecological Formulas

See all Ecological Formulas products
Name
ECOLOGICAL FORMULAS
Street Address
1061-B SHARY CIRCLE
City
CONCORD
State
CA
ZipCode
94518
Pharmacist Counseling Corner

Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas: Common Questions

Does Pro-Copper S.O.D. Mimetic Ligand by Ecological Formulas interact with any medications?
Yes. Based on its ingredients, Pro-Copper S.O.D. Mimetic Ligand has a known interaction with 31 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pro-Copper S.O.D. Mimetic Ligand contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is copper safe to take while pregnant?
Copper is actually needed during pregnancy, and recommended amounts are considered acceptable. However, avoid high-dose supplements without your doctor's or pharmacist's guidance. Talk with them to make sure the dose is right for your situation.
Does copper work for Alzheimer disease?
No — the evidence suggests copper may be ineffective for Alzheimer disease. If you're looking at this product hoping to help with cognitive decline, this isn't backed by the data.
What does copper do in my body?
Copper is an essential mineral that supports bone health, immune function, and iron metabolism. It's found naturally in foods like shellfish, nuts, and whole grains, and your body needs it in small amounts.
Can copper cause side effects?
Excess copper can be toxic, so staying within recommended amounts is important. A rare side effect is contact dermatitis — skin irritation from direct contact with copper — reported in a small number of people.
What's an S.O.D. Mimetic Ligand?
S.O.D. stands for superoxide dismutase, an enzyme that helps protect cells from damage. A 'mimetic ligand' means this product is formulated to work similarly to that enzyme. The active ingredient is copper.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pro-Copper S.O.D. Mimetic Ligand is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pro-Copper S.O.D. Mimetic Ligand label
Go deeper

The Full Monographs Behind Pro-Copper S.O.D. Mimetic Ligand’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

Pro-Copper S.O.D. Mimetic Ligand's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team