Probiotic 50B Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Probiotic 50B against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic 50B is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic 50B by Pure Encapsulations
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic 50B by Pure Encapsulations — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic 50B by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Probiotic 50B contains five active ingredients, all live probiotic bacteria: Bifidobacterium animalis lactis BL-04, Lactobacillus rhamnosus LR-32, Bifidobacterium longum BL-5, Lactobacillus acidophilus LA-14, and Lactobacillus plantarum LP-115. These strains are chosen to support your digestive and immune health.
The inactive ingredients—cellulose, gellan gum, and water—are the capsule and binding materials.
Does it work?
Moderate evidence
The evidence is mixed. Lactobacillus acidophilus (one strain in this product) is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
However, most of the conditions the other strains are marketed for—like age-related cognitive decline, hay fever, asthma, and athletic performance—have insufficient reliable evidence in our data to rate whether they work. If you're considering this product for a specific health issue, chat with your doctor or pharmacist about whether the science supports it for your situation.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Bifidobacterium longum is also generally well tolerated in healthy people, but caution is needed if you're seriously ill or immune-compromised.
Both strains can rarely cause mild gastrointestinal side effects like abdominal discomfort, bloating, flatulence, or constipation. There have been rare reports of serious infection (bacteremia or sepsis) in critically ill or preterm infants using probiotics, though these cases are uncommon.
The safety data for this product while breastfeeding are limited, so check with your doctor before use. For pregnancy, Bifidobacterium longum is rated possibly safe, and Lactobacillus acidophilus is possibly safe during pregnancy; however, the data are not comprehensive, so talk with your healthcare provider for personalized guidance.
Meds to double-check
Moderate interaction found
If you take antibiotic drugs, separate them from this probiotic by a few hours so the antibiotics don't kill off the live cultures. No other medication interactions are documented for the ingredients we could check.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Probiotic 50B may be worth considering if you're looking for digestive support, especially for antibiotic-related diarrhea or irritable bowel syndrome—though the evidence is strongest for one of its strains. The main thing to watch is timing with antibiotics: space them out by a few hours to protect the live cultures.
If you're seriously ill, immune-compromised, pregnant, breastfeeding, or take medications, check with your own doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic 50B, straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298013770 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 294040 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic 50B by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium animalis lactis BL-04 | 0 NP | -- |
| Lactobacillus rhamnosus LR-32 | 0 NP | -- |
| Bifidobacterium longum BL-5 | 0 NP | -- |
| Lactobacillus acidophilus LA-14 | 0 NP | -- |
| Probiotic Blend | 0 NP | -- |
| Lactobacillus plantarum LP-115 | 0 NP | -- |
Other ingredients: Cellulose, Cellulose, Gellan Gum, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Keep refrigerated
This formula requires refrigeration to maintain culture viability.
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule daily, with or between meals.
Precautions
Warning: Probiotics may be contraindicated for immunocompromised individuals.
If you are pregnant or lactating, have any health condition or are immunocompromised, or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
General Statements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements
Seals/Symbols
GFCO.org (Gluten-Free Certification Organization)
Formulation
Certified gluten free by the Gluten-Free Certification Organization, www.gluten.org
Gluten free, dairy free, soy free Non GMO & hypoallergenic
Gluten free, dairy free, soy free Non GMO & hypoallergenic
Natural color variations may occur
Formula
Acid-resistant capsules with pH targeted release; High-potency probiotic support for healthy intestinal microflora
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic 50B by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic 50B by Pure Encapsulations
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Probiotic Blend
Interacts with182 drugs
Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...
Probiotic Blend monograph & interactions- › Bifidobacterium animalis lactis BL-04
- › Lactobacillus rhamnosus LR-32
- › Bifidobacterium longum BL-5
- › Lactobacillus acidophilus LA-14
- › Lactobacillus plantarum LP-115
Other (inactive) ingredients: Cellulose, Cellulose, Gellan Gum, Water. These complete the product’s ingredient list but are not active constituents.
Probiotic 50B by Pure Encapsulations Drug Interactions
HelloPharmacist Interaction Report
Probiotic 50B from Pure Encapsulations contains several probiotic strains.
Two of them—Bifidobacterium longum and Lactobacillus acidophilus—have documented interactions, both with antibiotic drugs. The most serious concern is a Moderate-severity interaction: taking either strain alongside antibiotics might reduce how well the probiotics work, because antibiotics can kill off the live organisms in the supplement.
Read the full breakdown — every affected drug type, severity by severity
Bifidobacterium longum and Lactobacillus acidophilus interact the same way with antibiotics. Since both strains are living microorganisms, taking them at the same time as an antibiotic may eliminate a large portion of them before they can take effect.
The fix is straightforward: space out your antibiotic and this probiotic by a few hours, or ask your doctor or pharmacist for the best timing.
We could not check three other ingredients in this product—Bifidobacterium animalis lactis BL-04, Lactobacillus rhamnosus LR-32, and Lactobacillus plantarum LP-115—because we hold no interaction data for them. Altogether, these interactions span 182 individual medications.
Use the medication checker below to see if any of your prescriptions are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic 50B?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic 50B interact with 182 drugs. Click any drug to see the details.
1 of the 1 ingredient in Probiotic 50B interact with drugs. Each result below shows which ingredient is responsible. Probiotic Blend
AmikacinAmikin, Arikayce
How Amikacin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amikacin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin Veterinary interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Amphotericin, Tetracycline interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin, Sulbactam interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Avibactam Sodium, Ceftazidime interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Azithromycin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Aztreonam interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacampicillin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacitracin interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Benznidazole interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Capreomycin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Carbenicillin Indanyl Sodium interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefaclor interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefadroxil interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefamandole interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefazolin interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefdinir interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefditoren Pivoxil interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefepime interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefiderocol Sulfate Tosylate interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefixime interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefmetazole interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefonicid interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefoperazone interactionBifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Probiotic 50B — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bl-5Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bl-5 + Cefotaxime interactionProbiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic 50B with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Probiotic Blend
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Probiotic 50B, from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Probiotic 50B by Pure Encapsulations: Common Questions
Does Probiotic 50B by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this probiotic while I'm on antibiotics?
What does this product actually do?
Are there side effects?
Is it safe to take while pregnant or breastfeeding?
How many live cultures does each capsule contain?
Will this help with my allergies or asthma?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic 50B’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph →Sources & How We Checked
Probiotic 50B's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC