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Dietary supplement

Probiotic Solutions Multi Strain 25 Billion CFUs Ingredients & Drug Interactions

by GNC Probiotic Solutions

Probiotic Solutions Multi Strain 25 Billion CFUs label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic Solutions Multi Strain 25 Billion CFUs against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic Solutions Multi Strain 25 Billion CFUs is a dietary supplement by GNC Probiotic Solutions with 2 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 17 active ingredients.
  • “LAB4 Probiotics” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Multi-Strain Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Probiotic Complex” is a proprietary blend — the label doesn't break down how much of each component you get.

This product has 17 active ingredients: multiple strains of beneficial bacteria (Lactobacillus acidophilus in three forms, Lactobacillus gasseri, Lactobacillus salivarius, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus fermentum, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium lactis, Bifidobacterium animalis subsp. lactis, Pediococcus pentosaceus, and Streptococcus thermophilus), plus fructooligosaccharides — a prebiotic that feeds beneficial bacteria. The 25 billion CFUs refers to the total number of live organisms per serving.

The inactive ingredients are vegetarian capsule shell, silica, magnesium stearate, and titanium dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and gut microbiome balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Diarrhea, Colic, lactose intolerance, gut dysbiosis — and 1 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation, Colic.
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation, Travelers' diarrhea.

The evidence for these probiotics varies by strain and condition. Lactobacillus acidophilus strains are rated Possibly Effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Bifidobacterium bifidum and Bifidobacterium lactis are also rated Possibly Effective for IBS and respiratory tract infections; Bifidobacterium lactis specifically is Possibly Effective for constipation. For most other uses listed in the data—hay fever, asthma, common cold, and various other conditions—the evidence is Insufficient to rate.

Fructooligosaccharides and Streptococcus thermophilus lack established evidence in our data for the conditions we hold information on. Talk with your doctor about whether this product fits your specific health goal.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotics in this formula are generally well tolerated in healthy adults and children. The most common side effects are mild digestive complaints: bloating, flatulence, abdominal discomfort, and diarrhea.

These are uncommon when taken as directed. Fructooligosaccharides can cause gas and bloating, especially at higher doses, though studies show doses under 10 grams daily don't increase these effects compared to placebo.

Because these are live organisms, there's a theoretical concern they could cause infection in people with severely weakened immune systems or critical illness; such cases are rare. Two rashes were reported in one trial combining multiple probiotics, though it's unclear which ingredient was responsible.

For pregnancy and lactation: Lactobacillus acidophilus strains and Bifidobacterium species are rated Possibly Safe in pregnancy. Lactation data aren't on file for most ingredients.

Discuss use during pregnancy or breastfeeding with your doctor.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 7 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Animalis Subsp. Lactis, Bifidobacterium Breve, Bifidobacterium Bifidum, Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, you need to discuss timing with your pharmacist before taking this probiotic. Antibiotics may kill the live organisms in the supplement, reducing its effectiveness.

Separating doses can help. No interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-strain probiotic aimed at supporting digestive and immune health, with Possibly Effective evidence for IBS, antibiotic-related diarrhea, and some bacterial infections. It's generally well tolerated but can cause mild digestive bloating or gas, especially when starting.

The key caution is taking it with antibiotics — you'll want to separate doses to protect the live organisms. If you have a weakened immune system, take blood thinners, or are pregnant or nursing, check with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 17 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic Solutions Multi Strain 25 Billion CFUs, straight from the product label.

Brand GNC Probiotic Solutions
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 77147
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Fructooligosaccharides100 mg--
Lactobacillus rhamnosus HN0010 NP--
Bifidobacterium lactis HN0190 NP--
Lactobacillus paracasei (CUL 08)0 NP--
LAB4 Probiotics0 NP--
Lactobacillus acidophilus (CUL 60)0 NP--
Lactobacillus acidophilus (CUL 21)0 NP--
Bifidobacterium bifidum (CUL 20)0 NP--
Bifidobacterium animalis subsp. lactis (CUL 34)0 NP--
Multi-Strain Blend0 NP--
Lactobacillus salivarius (CUL 61)0 NP--
Lactobacillus plantarum (CUL 66)0 NP--
Lactobacillus acidophilus NCFM0 NP--
Lactobacillus casei (CUL 06)0 NP--
Lactobacillus gasseri (CUL 09)0 NP--
Bifidobacterium breve (CUL 74)0 NP--
Probiotic Complex0 NP--
Lactobacillus fermentum (CUL 67)0 NP--
Pediococcus pentosaceus (CUL 15)0 NP--
Streptococcus thermophilus (CUL 68)0 NP--

Other ingredients: Vegetarian Capsule Shell, Silica, Magnesium Stearate, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

CODE 424631 IRG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily with food.

Formulation

Gluten free, lactose free.

Seals/Symbols

Gf Gluten free

General Statements

Why GNC Probiotic Solutions Multi Strain? 16 strains of live, active probiotic cultures

Guaranteed potency through expiration date

Actual size

Made in the UK

Potency guaranteed 25 billion CFUs

16 unique strains, including clinically studied probiotics Provides a wide range of probiotic strains for digestive & immune support

25 billion active cultures

Guaranteed potency Probiotic Solutions Multi Strain has been tested to ensure the full 25 billion cultures in each dose are live and active when used by the expiration date.

Formula

Prebiotic FOS

Storage

No refrigeration necessary

Store in a cool, dry place. No refrigeration required.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic Solutions Multi Strain 25 Billion CFUs label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fructooligosaccharides

No known
interactions
100 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Fructooligosaccharides monograph & interactions

Probiotic Complex

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Complex monograph & interactions
  • › LAB4 Probiotics
  • › Multi-Strain Blend

Other (inactive) ingredients: Vegetarian Capsule Shell, Silica, Magnesium Stearate, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions Drug Interactions

Want to check YOUR meds against Probiotic Solutions Multi Strain 25 Billion CFUs?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Probiotic Complex 182

Individual Drug Interactions

The ingredients in Probiotic Solutions Multi Strain 25 Billion CFUs interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Probiotic Solutions Multi Strain 25 Billion CFUs interact with drugs. Each result below shows which ingredient is responsible. Probiotic Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic Solutions Multi Strain 25 Billion CFUs with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Complex1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Probiotic Solutions Multi Strain 25 Billion CFUs, from the product label.

GNC Probiotic Solutions

See all GNC Probiotic Solutions products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions: Common Questions

Does Probiotic Solutions Multi Strain 25 Billion CFUs by GNC Probiotic Solutions interact with any medications?
Yes. Based on its ingredients, Probiotic Solutions Multi Strain 25 Billion CFUs has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic Solutions Multi Strain 25 Billion CFUs contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on antibiotics?
Not at the same time. The antibiotic will likely kill the live bacteria in the probiotic, making it ineffective. Ask your pharmacist how many hours to wait between taking them — typically it's a few hours apart, but it depends on which antibiotic you're taking.
What's the difference between these probiotics and prebiotics?
This product has both. The probiotics are the live beneficial bacteria (the Lactobacillus and Bifidobacterium strains). The fructooligosaccharides (FOS) are a prebiotic — they're food for those bacteria to help them grow.
Will this cause bloating or gas?
Mild bloating and gas are possible, especially when you first start taking probiotics or fructooligosaccharides. These side effects are usually uncommon and tend to settle down, but if they bother you, mention it to your pharmacist.
Is this safe to take during pregnancy?
Some of the Lactobacillus and Bifidobacterium strains are rated Possibly Safe in pregnancy, but we don't have full safety data on all ingredients. Talk it over with your doctor before starting — they know your situation and can give you personalized advice.
What is IBS, and does this really help?
IBS is irritable bowel syndrome — a digestive condition with cramping, bloating, and irregular bowel habits. Several of the probiotics here are rated Possibly Effective for IBS based on clinical studies, meaning the evidence suggests they may help, but they don't work for everyone.
What are CFUs, and does 25 billion sound like a lot?
CFU stands for colony-forming units — it's how we count live bacteria in a probiotic. Different products use different doses, and research suggests different amounts work for different purposes. Your doctor can tell you if this dose fits what you need.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic Solutions Multi Strain 25 Billion CFUs is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic Solutions Multi Strain 25 Billion CFUs label
Go deeper

The Full Monographs Behind Probiotic Solutions Multi Strain 25 Billion CFUs’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Probiotic Solutions Multi Strain 25 Billion CFUs's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 78 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
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See these in context on the Lactobacillus Gasseri monograph →

Bifidobacterium Breve 9 references
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See these in context on the Bifidobacterium Breve monograph →

Streptococcus Thermophilus 21 references
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See these in context on the Streptococcus Thermophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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