Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Pump Formula Cotton Candy Ingredients & Drug Interactions

by BPI Sports

Pump Formula Cotton Candy label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pump Formula Cotton Candy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Pump Formula Cotton Candy is a dietary supplement by BPI Sports with 5 active ingredients. Its ingredients are commonly taken for constipation (laxative), dry skin (moisturizer), dry, irritated eyes.Based on those ingredients, 638 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Diindolylmethane, Velvet Bean extract, L-Citrulline Malate 1:1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pump Formula Cotton Candy by BPI Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with Pump Formula Cotton Candy by BPI Sports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pump Formula Cotton Candy by BPI Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Pump Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Anti-Estrogenic Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.01 mg) without saying how much of each component you get.

Pump Formula Cotton Candy contains 5 active ingredients. Diindolylmethane is a plant compound studied for hormone-related effects.

Calcium D-Glucarate provides calcium and a naturally occurring sugar compound. Glycerol is a simple sugar alcohol used to draw fluid into muscle tissue and support hydration.

Velvet Bean extract (also called cowhage) contains levodopa, the same compound used in Parkinson's disease medication. L-Citrulline Malate is an amino acid that converts to arginine in your body and may support blood flow and exercise performance.

The formula also includes a Pump Blend and Anti-Estrogenic Proprietary Blend whose exact components aren't itemized on the label. Beyond the actives, the powder contains natural and artificial flavors, citric acid, silica, sucralose, acesulfame-K, and maltodextrin as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: maximum vasodilation and muscle pump for exercise.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, blood flow, nitric oxide, endurance.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

Evidence for most of this product's ingredients is limited. Diindolylmethane has been studied for prostate health, breast health, and cancer prevention, but the data we hold shows insufficient evidence to rate any of those uses.

Glycerol is likely effective for occasional constipation and possibly effective for athletic performance, though the doses and context matter. L-Citrulline Malate is possibly effective for athletic performance — some research suggests it may help with endurance — but evidence for heart health or muscle-building is insufficient or mixed.

Velvet Bean extract's effectiveness for anxiety, Parkinson's disease, or other conditions we have on file shows insufficient evidence. Calcium D-Glucarate's ingredient, calcium itself, is effective for preventing kidney-related low calcium and likely effective for bone health, but calcium D-glucarate's own role in this product's claimed benefits isn't established in the data we hold.

The evidence, ingredient by ingredient Glycerol L-citrulline Diindolylmethane Calcium Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Diindolylmethane is generally well tolerated in short-term studies, but long-term safety hasn't been established; the most common side effects are gastrointestinal (diarrhea, gas, nausea) and headache. A rare but serious rash condition called DRESS has been reported.

Calcium is well tolerated at recommended doses, though high amounts raise theoretical concerns about kidney stones and cardiovascular risk; common side effects are constipation and gas. Glycerol is well tolerated in normal amounts but can cause bloating, nausea, and diarrhea in larger doses.

Velvet Bean extract contains an active drug-like compound and should be used carefully; reported side effects include flatulence, diarrhea, and headache, with insomnia occurring in a small number of trial participants. L-Citrulline is generally well tolerated, with gastrointestinal discomfort and heartburn as the main reported issues.

Regarding pregnancy, Diindolylmethane is rated likely safe; Calcium is likely safe in adequate amounts; Glycerol and L-Citrulline Malate have insufficient data — there isn't enough information to know either way, so discuss with your doctor. For breastfeeding, safety data advises against Diindolylmethane and Velvet Bean extract (which may reduce milk supply through its levodopa content); data for Calcium, Glycerol, and L-Citrulline is insufficient, so check with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Glycerol L-citrulline Diindolylmethane Calcium Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Calcium, Cowhage, Diindolylmethane, L-citrulline.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 638 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use methyldopa or other blood pressure medications, monoamine oxidase inhibitors (MAOIs) or other antidepressants, HIV medications like dolutegravir or raltegravir, thyroid medication, diabetes medication, heart rhythm drugs, antipsychotic medication, or estrogen-based birth control or hormone therapy. The interactions span Major and Moderate severity levels and can significantly reduce how well some of these drugs work or raise blood pressure dangerously.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient pre-workout powder aimed at muscle pump and performance. If you take blood pressure medication, antidepressants, mood stabilizers, diabetes medication, thyroid medication, HIV drugs, or use birth control or hormone replacement therapy, you need to review your specific medications against this product before starting — the interactions are serious and can affect drug levels or blood pressure significantly.

Even without those, talk with your doctor or pharmacist to make sure this product fits your health picture and current routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pump Formula Cotton Candy, straight from the product label.

Brand BPI Sports
Net contents 8.46 Ounce(s); 240 Gram(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 265872
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pump Formula Cotton Candy by BPI Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.6 Gram(s)
Maximum serving Sizes:
7.6 Gram(s)
Servings per container
30
IngredientAmount% DV
Diindolylmethane0 NP--
Calcium D-Glucarate0 NP--
Glycerol2 Gram(s)--
Pump Blend0 NP--
Velvet Bean extract0 NP--
L-Citrulline Malate 1:13 Gram(s)--
Anti-Estrogenic Proprietary Blend1.01 mg--

Other ingredients: Natural & Artificial Flavors, Citric Acid, Silica, Sucralose, Acesulfame-K, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Maximum Vasodilation & Extreme Cellular Volumization Cotton Candy Natural & Artificial Flavors

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 serving (1 scoop), mix in 8 oz of cold water, pre, intra or post exercise, or as directed by a qualified healthcare practitioner.

Formula

L-Citrulline Malate Increase blood flow Boost nitric oxide levels Endurance Glycerol Monostearate Quick absorption Muscle pumps Exercise efficiency Velvet bean extract (mucuna pruriens) Naturally supports healthy hgh levels Muscle recovery Lean muscle building Sexual libido & performance Dindolylmethane (DIM) Naturally supports healthy testosterone and hormone levels Lean, dry muscle gains Anti-Estrogenic

General Statements

Mike O'Hearn The Titan Series

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pump Formula Cotton Candy by BPI Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pump Formula Cotton Candy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pump Formula Cotton Candy by BPI Sports

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.6 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pump Blend

0 NP per serving

Anti-Estrogenic Proprietary Blend

1.01 mg per serving

Other (inactive) ingredients: Natural & Artificial Flavors, Citric Acid, Silica, Sucralose, Acesulfame-K, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pump Formula Cotton Candy by BPI Sports Drug Interactions

Want to check YOUR meds against Pump Formula Cotton Candy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
638Drugs
24 Major 479 Moderate 135 Minor

Ingredients driving the most interactions

Diindolylmethane 269
Velvet Bean extract 193
L-Citrulline Malate 1:1 178
Calcium D-Glucarate 168

Individual Drug Interactions

The ingredients in Pump Formula Cotton Candy interact with 638 drugs. Click any drug to see the details.

4 of the 5 ingredients in Pump Formula Cotton Candy interact with drugs. Each result below shows which ingredient is responsible. Diindolylmethane Velvet Bean extract L-Citrulline Malate 1:1 Calcium D-Glucarate

Each ingredient & the kinds of drugs it affects

For each ingredient in Pump Formula Cotton Candy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Diindolylmethane3 drug types · 269 drugs

Diuretic Drugs

Theoretically, diindolylmethane might increase the risk of hyponatremia if used with sodium-depleting diuretics.
Large doses of diindolylmethane (600 mg daily) have been associated with two cases of asymptomatic hyponatremia in clinical research.

Likelihood Possible Evidence B
Estrogens

Theoretically, diindolylmethane might increase or decrease the effects of estrogens.
Diindolylmethane might have mild estrogenic or antiestrogenic effects. Theoretically, large amounts of diindolylmethane might interfere with hormone replacement therapy.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, diindolylmethane might lower serum levels of CYP1A2 substrates.
In vitro evidence suggests that diindolylmethane can induce CYP1A2. Theoretically, it might increase metabolism of CYP1A2 substrates and lower serum concentrations. This interaction has not been reported in humans.

Likelihood Unlikely Evidence D
Diindolylmethane full monograph & interactions

Velvet Bean extract8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Velvet Bean extract full monograph & interactions

L-Citrulline Malate 1:12 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline Malate 1:1 full monograph & interactions

Calcium D-Glucarate18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium D-Glucarate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pump Formula Cotton Candy, from the product label.

BPI Sports

See all BPI Sports products
Name
BPI
Pharmacist Counseling Corner

Pump Formula Cotton Candy by BPI Sports: Common Questions

Does Pump Formula Cotton Candy by BPI Sports interact with any medications?
Yes. Based on its ingredients, Pump Formula Cotton Candy has a known interaction with 638 medications, including 24 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pump Formula Cotton Candy contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Velvet Bean extract in this formula have any side effects?
Velvet Bean extract is generally well tolerated, but can cause flatulence, diarrhea, headache, and dry mouth. A small number of trial participants reported insomnia. Since it contains levodopa, an active drug-like compound, it should be used carefully and with professional guidance.
Is this safe to take if I'm pregnant or breastfeeding?
Diindolylmethane is rated likely safe in pregnancy. Calcium is likely safe at adequate amounts. For the other ingredients, there isn't enough safety data to know either way — talk with your doctor or pharmacist for personalized advice. If breastfeeding, Velvet Bean extract may reduce milk supply, so avoid it; Diindolylmethane safety data advises against it; and the others need discussion with your provider.
Does this product help with athletic performance?
L-Citrulline Malate is possibly effective for athletic performance based on the data we hold. Glycerol is also possibly effective for exercise performance. Neither has overwhelming evidence, so results vary between people.
What is Velvet Bean extract used for in this formula?
Velvet Bean extract (cowhage) contains levodopa, an amino acid that converts to dopamine in your body and may support blood flow and muscle pump. It's used here as a pre-workout ingredient, though evidence for its effectiveness in this context is insufficient.
What are the common side effects of the calcium in this product?
Calcium at typical doses usually causes no problems, but common mild side effects include constipation, gas, bloating, and stomach upset. At very high doses, there's theoretical concern about kidney stones, though this is rare.
Can I take this if I'm on thyroid medication?
The calcium in this formula can reduce how much thyroid medication your body absorbs. Talk with your doctor or pharmacist before combining them — they may recommend taking this product several hours apart from your thyroid pill.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pump Formula Cotton Candy label
Go deeper

The Full Monographs Behind Pump Formula Cotton Candy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Diindolylmethane

Interacts with 269 drugs

Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone balance and cancer prevention. Although early lab s...

Read the full Diindolylmethane monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Pump Formula Cotton Candy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 104 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Diindolylmethane 14 references
  1. Natl Inst Health, Natl Inst Environmental Health Sci. Indole-3-carbinol. Available at: http://ntp-server.niehs.nih.gov.
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Glycerol 8 references
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  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
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Cowhage 12 references
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L-citrulline 8 references
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