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Dietary supplement

Pure L-Glutamine Powder Free Form Ingredients & Drug Interactions

by Vitamin World

Pure L-Glutamine Powder Free Form label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure L-Glutamine Powder Free Form against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure L-Glutamine Powder Free Form is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pure L-Glutamine Powder Free Form by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure L-Glutamine Powder Free Form by Vitamin World — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pure L-Glutamine Powder Free Form by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine (the free form, meaning it's not bound to other compounds). L-glutamine is an amino acid your body uses for gut health, immune function, and muscle recovery, especially after stress, surgery, or intense exercise.

There are no inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glutamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Natural Medicines).

L-glutamine is rated effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is possibly effective—meaning there's some promise, but more research is needed to be certain.

The facts we hold don't cover every use you might see marketed for this product, so if you're considering it for another reason, that's worth discussing with your doctor.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults. The most common side effects from oral use are digestive—belching, bloating, flatulence, nausea, constipation, and diarrhea—especially at higher doses (10–30 grams daily).

Headache and musculoskeletal pain have also been reported. A small number of people with bipolar disorder have reported mood changes (mania or hypomania) while taking glutamine; if you have bipolar disorder or a history of mood instability, bring that up with your doctor before starting.

If you have kidney or liver disease, use only under medical supervision. The data on safety in pregnancy is rated likely safe, but safety information during breastfeeding is limited, so talk it over with your doctor or pharmacist if you're nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure drugs, or medications prescribed for nerve pain or mood stabilization that are in the anticonvulsant class), check your exact medication with the search tool below before starting this product. This is a moderate-severity concern, and your doctor or pharmacist needs to know you're considering glutamine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

L-glutamine may help with sickle cell disease and shows promise for recovery after surgery or serious illness. If you take anticonvulsant (seizure) medications, check with your own doctor or pharmacist first.

Healthy adults usually tolerate it well, though digestive upset and headache can happen—start with a lower dose if you're new to it. If you have kidney or liver disease, bipolar disorder, or are pregnant or breastfeeding, talk with your doctor before taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure L-Glutamine Powder Free Form, straight from the product label.

Brand Vitamin World
Barcode (UPC) 766443678090
Net contents 14.1 Oz(s); 400 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2016
DSLD ID 62657
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure L-Glutamine Powder Free Form by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
Servings per container
89
UPC/BARCODE
766443678090
IngredientAmount% DV
Calories20 Calorie(s)--
L-Glutamine4400 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Quality Assured

Brand IP Statement(s)

At Vitamin World we ensure the quality of all of our premium nutritional products, every step of the way. Strict quality analysis at world-class facilities guarantees that all Vitamin World products are at the highest standard of potency and purity.

2016 Vitamin World, Inc.

Nutrition from the source

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Suitable for vegetarians

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

General Statements

Contents are sold by weight. Some settling may occur.

To reorder prod. #67809 www.vitaminworld.com 1-800-228-4533

Conditionally essential amino acid important fuel for the GI system protein building block

Amino Acids are the building blocks of protein, which play a role in normal growth and development. Glutamine is the most abundant free form amino acid in blood and skeletal muscle. It can serve as an energy precursor and is involved in more metabolic processes than any other amino acid. Hard training can decrease glutamine levels, which is why it’s used by bodybuilders and athletes everywhere.

General

Product No. 67809 B67808 02B

Formula

Amino Acids

FDA Statement of Identity

Amino Acid Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, mix one (1) teaspoon (4.5 g) into 4-8 ounces of water or your favorite beverage one to two times daily.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure L-Glutamine Powder Free Form by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure L-Glutamine Powder Free Form label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure L-Glutamine Powder Free Form by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 tsp Dosage formPowder Servings per container89 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
4400 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Pure L-Glutamine Powder Free Form by Vitamin World Drug Interactions

Want to check YOUR meds against Pure L-Glutamine Powder Free Form?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Pure L-Glutamine Powder Free Form interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pure L-Glutamine Powder Free Form interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure L-Glutamine Powder Free Form with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure L-Glutamine Powder Free Form, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Holbrook
State
NY
ZipCode
11741
Phone Number
1-800-228-4533
Web Address
www.vitaminworld.com
Pharmacist Counseling Corner

Pure L-Glutamine Powder Free Form by Vitamin World: Common Questions

Does Pure L-Glutamine Powder Free Form by Vitamin World interact with any medications?
Yes. Based on its ingredients, Pure L-Glutamine Powder Free Form has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure L-Glutamine Powder Free Form contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm pregnant or breastfeeding?
During pregnancy, L-glutamine is rated likely safe. During breastfeeding, there isn't enough safety data available—talk with your doctor or pharmacist to decide whether it's right for you.
What's the most common side effect?
Digestive upset is most common: bloating, flatulence, nausea, diarrhea, or constipation. These tend to happen more often at higher doses. Starting with a smaller amount and working up may help.
Does it really work for muscle recovery?
The data we hold rates it effective for sickle cell disease and possibly effective for postoperative recovery and critical illness. For general athletic recovery, the evidence isn't established in our data, so that's a question for your doctor.
Can I take this if I have kidney or liver disease?
You can, but only under medical supervision. Talk with your doctor before starting it.
What is L-glutamine actually used for in the body?
It's an amino acid your body uses to support gut health, immune function, and muscle repair—especially after stress, surgery, or strenuous exercise.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure L-Glutamine Powder Free Form is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure L-Glutamine Powder Free Form label
Go deeper

The Full Monographs Behind Pure L-Glutamine Powder Free Form’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Pure L-Glutamine Powder Free Form's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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