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Dietary supplement

RapidDrive Amino Series Glutamine 5000 Unflavored Ingredients & Drug Interactions

by GNC Pro Performance

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

RapidDrive Amino Series Glutamine 5000 Unflavored is a dietary supplement by GNC Pro Performance with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine, Micronized. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, micronized (5000 mg per serving, based on the product name). Glutamine is an amino acid — one of the building blocks your body uses to make protein.

It's naturally present in foods and your own body, and it plays roles in immune function, gut health, and muscle recovery, particularly after illness, surgery, or intense physical stress.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and sports performance support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Muscle protein synthesis, Sports recovery — and 1 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Exercise-induced muscle damage.

The evidence supporting glutamine is strongest for sickle cell disease, where it's rated Effective. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is rated Possibly Effective — meaning there's some promise, but more research is needed to be certain.

The data we hold doesn't establish effectiveness for general athletic performance or muscle building.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults when taken by mouth. The most common side effects are digestive: belching, bloating, constipation, flatulence, nausea, vomiting, diarrhea, and abdominal pain.

A small number of users have also reported headache, cough, and musculoskeletal pain. Two cases of mania or hypomania have been reported in people with bipolar disorder taking up to 4 grams daily; if you have bipolar disorder, talk with your doctor before starting.

People with kidney or liver disease should use glutamine only under medical supervision. There isn't enough reliable safety data to recommend supplemental doses during breastfeeding unless your doctor advises it.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure-prevention drugs), check your exact medication names in the search tool below before starting this product, and confirm with your doctor or pharmacist that it's safe to combine. This is a Moderate-severity theoretical interaction.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward single-ingredient glutamine supplement that may help with sickle cell disease, muscle recovery after surgery or trauma, and HIV-related wasting — though the last two need more evidence. The main caution is if you take anticonvulsant medications: check your specific drugs with the tool on this page and confirm with your doctor or pharmacist before adding it.

If you have bipolar disorder, kidney disease, or liver disease, talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about RapidDrive Amino Series Glutamine 5000 Unflavored, straight from the product label.

Brand GNC Pro Performance
Barcode (UPC) 048107090777
Net contents 10.56 oz.; 300 Gram(s)
Market status On market
Date entered into DSLD May 24, 2017
DSLD ID 74473
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
60
UPC/BARCODE
048107090777
IngredientAmount% DV
L-Glutamine, Micronized5000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Daily Post-Workout

Directions: As a dietary supplement, mix one serving (5 g) with 4-6 fl. oz. of water, juice or your favorite sports drink daily or after exercise.

General Statements

Glutamine is one of the most abundant amino acids. It is involved in protein synthesis and plays an important role in hydrating muscle cells. With this amino acid's great benefits in the body, it will support muscle function.

The glutamine molecules have been pulverized, or "micronized", from large molecules into smaller particles that deliver fast fuel for powerful performance and are easier for muscles to absorb. You can expect recovery support with this rapid source of intramuscular nitrogen. The result is a powerful anti-catabolic formula. Best of all, it mixes easily in any beverage or sports drink and tastes absolutely refreshing.

Informed-Choice.org Trusted by sport This product has been tested for banned substances by HFL Sport Science, a world-class anti-doping lab, Product was tested for over 145 banned substances on the 2013 World Anti-Doping Agency (WADA) Prohibited List via HFL skip lot testing protocol #ICP0307. See gnc.com for more information.

60 servings

Notice: Significant product settling may occur.

Brand IP Statement(s)

This unique RapidDrive Technology makes this supplement more advanced than regular glutamine supplements.

Stack with Pro Performance: RapidDrive Arginine 5000, RapidDrive BCAA 5000 and 100% Whey Protein.

Nitro-Factor 6g

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

Micronized Glutamine for recovery & anti-catabolic effects

General

Code 351189 FOG

Formulation

No sugar.

Banned substance free

Precautions

Keep out of reach of children.

Storage

Store in a cool, dry place.

See for yourself

RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

L-Glutamine, Micronized

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine, Micronized monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance Drug Interactions

Want to check YOUR meds against RapidDrive Amino Series Glutamine 5000 Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in RapidDrive Amino Series Glutamine 5000 Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine, Micronized1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for RapidDrive Amino Series Glutamine 5000 Unflavored, from the product label.

GNC Pro Performance

See all GNC Pro Performance products
Name
General Nutrition Corp.
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
www.gnc.com
Pharmacist Counseling Corner

RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance: Common Questions

Does RapidDrive Amino Series Glutamine 5000 Unflavored by GNC Pro Performance interact with any medications?
Yes. Based on its ingredients, RapidDrive Amino Series Glutamine 5000 Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
RapidDrive Amino Series Glutamine 5000 Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
Glutamine is rated Likely Safe in pregnancy, so it's generally considered okay. During breastfeeding, though, there isn't enough reliable safety data. Talk with your doctor or pharmacist before taking supplemental glutamine while nursing.
What does glutamine actually do in my body?
Glutamine is an amino acid your body uses to make protein and support immune function, gut health, and muscle recovery — especially after surgery, illness, or physical stress. It's also naturally present in foods like chicken, beef, dairy, and some vegetables.
Will this help my athletic performance or muscle building?
The data we hold doesn't establish that glutamine is effective for general athletic performance or muscle growth. The strongest evidence supports its use in sickle cell disease and recovery from surgery or critical illness.
What are the most common side effects?
Digestive issues are the most common: bloating, gas, nausea, diarrhea, constipation, and abdominal pain. Headache and cough have also been reported. Most people tolerate it well, but start with a lower dose if you're new to it.
Is there any reason I shouldn't take this?
If you have kidney or liver disease, only take it under your doctor's supervision. If you have bipolar disorder, check with your doctor first — a couple of cases of mania have been reported with glutamine. Also confirm with your doctor if you take anticonvulsant (seizure-prevention) medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if RapidDrive Amino Series Glutamine 5000 Unflavored is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

RapidDrive Amino Series Glutamine 5000 Unflavored label
Go deeper

The Full Monographs Behind RapidDrive Amino Series Glutamine 5000 Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

RapidDrive Amino Series Glutamine 5000 Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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