Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Regeneration Ingredients & Drug Interactions

by EN Enraged

Regeneration label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Regeneration against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Regeneration is a dietary supplement by EN Enraged with 4 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Regeneration by EN Enraged

Ask about any prescription or over-the-counter medication and we check it for interactions with Regeneration by EN Enraged — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Regeneration by EN Enraged

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Regeneration contains four active ingredients, all branched-chain amino acids (BCAAs) — building blocks your body uses to build and repair muscle and tissue. You get L-Glutamine, L-Leucine, L-Isoleucine, and L-Valine in capsule form.

The capsule itself is made from gelatin, an inactive ingredient used to hold the powder inside.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle growth, recovery and protein synthesis.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Muscle strength, Muscle endurance — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Exercise-induced muscle damage.

L-Glutamine is rated Effective for sickle cell disease. It's rated Possibly Effective for HIV/AIDS-related wasting, postoperative recovery (healing after surgery), and recovery from critical illness or trauma.

The effectiveness ratings for the other three amino acids in this product aren't established in our data.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated in healthy adults. The most common side effects are digestive: belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and stomach pain.

Headache and musculoskeletal pain have also been reported. If you have kidney or liver disease, use this product only under medical supervision.

There isn't enough reliable safety data to recommend it during pregnancy or while breastfeeding unless a doctor advises it — talk to your clinician for personalized guidance. We don't have safety data on file for L-Leucine, L-Isoleucine, or L-Valine in this product.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant (seizure) medications, double-check with your pharmacist before using this product — L-Glutamine might reduce how well they work, though this hasn't been confirmed in patients yet. For your other medications, use the checker on this page to look up your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Regeneration may be worth considering if you're recovering from surgery or critical illness, or managing HIV-related muscle loss — but it's most established for sickle cell disease. If you take seizure medications (anticonvulsants) or have kidney or liver disease, check with your pharmacist first.

Pregnant or breastfeeding? Talk to your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Regeneration, straight from the product label.

Brand EN Enraged
Barcode (UPC) 818423026190
Net contents 150 Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 256635
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Regeneration by EN Enraged, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Capsule(s)
Maximum serving Sizes:
5 Capsule(s)
Servings per container
30
UPC/BARCODE
818423026190
IngredientAmount% DV
L-Glutamine1500 mg--
L-Leucine850 mg--
L-Isoleucine425 mg--
L-Valine425 mg--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

To achieve results you must work hard, and that takes a lot out of you. Fuel your starving muscles with this powerful matrix of branched-chain amino acids-for muscle growth, recovery and protein synthesis.

L-Glutamin helps support immunity

Suggested/Recommended/Usage/Directions

We recommend you take Enraged Regeneration before bed, regenerate yourself with the building blocks your body uses to support lean muscle, and be ready to go again in the morning!

Directions: Take one serving (5 capsules) 20 minutes before bedtime.

Formulation

Promotes efficient muscle recovery Supports lean muscle mass Synthesizes muscle protein

Recovery blast Increase muscle rejuvenation

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Consult with a health care professional before using this product.

Do not use if pregnant or lactating.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Regeneration by EN Enraged label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Regeneration label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Regeneration by EN Enraged

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
1500 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

L-Leucine

850 mg per serving

L-Isoleucine

425 mg per serving

L-Valine

425 mg per serving

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Regeneration by EN Enraged Drug Interactions

Want to check YOUR meds against Regeneration?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Regeneration interact with 50 drugs. Click any drug to see the details.

1 of the 4 ingredients in Regeneration interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Regeneration with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Regeneration, from the product label.

EN Enraged

See all EN Enraged products
Name
Enraged Nutrition, LLC
Street Address
9160 E. Bahia Dr. Suite #200
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
www.enraged.com
Pharmacist Counseling Corner

Regeneration by EN Enraged: Common Questions

Does Regeneration by EN Enraged interact with any medications?
Yes. Based on its ingredients, Regeneration has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Regeneration contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine safe if I'm pregnant or breastfeeding?
The safety data rates glutamine as Likely Safe in pregnancy. However, there isn't enough reliable information for breastfeeding — the data advises against supplement doses unless your doctor or lactation consultant recommends it. Talk to your clinician for advice tailored to your situation.
What are the most common side effects?
Most side effects are digestive: bloating, flatulence, constipation, diarrhea, nausea, vomiting, and stomach pain. Belching, headache, and musculoskeletal pain have also been reported. These were generally manageable in studies, but let your pharmacist know if they bother you.
Will this help me build muscle or recover from a workout?
L-Glutamine is rated Possibly Effective for recovery after surgery and critical illness. The effectiveness data for muscle-building or workout recovery specifically isn't established in our information.
Do I need to worry about the other three amino acids interacting with my medications?
We don't hold interaction data for L-Leucine, L-Isoleucine, or L-Valine, so we can't check them. That doesn't mean they're safe — just that we haven't verified their interactions. Use the medication checker on this page to search your exact drugs.
Can I take this if I have kidney or liver disease?
L-Glutamine should only be used under medical supervision if you have kidney or liver disease. Talk to your doctor before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Regeneration is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Regeneration label
Go deeper

The Full Monographs Behind Regeneration’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Regeneration's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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