Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Rice Protein Powder Plain Ingredients & Drug Interactions

by NutriBiotic

Rice Protein Powder Plain label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rice Protein Powder Plain against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rice Protein Powder Plain is a dietary supplement by NutriBiotic with 5 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,043 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Manganese, Iron. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Rice Protein Powder Plain by NutriBiotic

Ask about any prescription or over-the-counter medication and we check it for interactions with Rice Protein Powder Plain by NutriBiotic — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Rice Protein Powder Plain by NutriBiotic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains 3 active ingredients: iron, manganese, and rice protein. Iron is included to help prevent or treat iron deficiency anemia.

Manganese supports normal bone and connective tissue formation, though it's also naturally present in many foods. Rice protein provides amino acids for muscle support and recovery.

The product also contains rice protein as an inactive ingredient (a base for the powder).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: high quality vegan protein powder.
  • We looked for evidence on: muscle health, athletic performance, protein deficiency.
  • The closest evidence on file: Iron is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).

Iron is proven effective for iron deficiency anemia and anemia of chronic disease, as well as for pregnancy-related iron deficiency. It's possibly effective for heart failure.

Manganese is effective for manganese deficiency, but evidence for hay fever, osteoporosis, COPD, weight loss, and osteoarthritis is not reliable enough to rate. Rice protein itself has no effectiveness data on file—this product is formulated as a protein source rather than a therapeutic supplement for a specific condition.

The evidence, ingredient by ingredient Black Psyllium Iron Manganese

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iron and manganese are both generally well tolerated at recommended doses. The main side effects from oral iron are gastrointestinal: abdominal pain, constipation, diarrhea, nausea, and vomiting.

Serious side effects are rare but can include ulceration of the stomach or small intestine. At high doses, manganese can cause neurotoxicity and Parkinson-like symptoms; one severe case linked high-dose manganese use (100 mg daily for 2–4 years) to irreversible Parkinson disease.

There's also concern that excess iron over time may increase the risk of heart problems in some people, though research is mixed on this. Iron should be used only when there's a real need, and excess iron can be toxic.

During pregnancy, iron is often recommended, but dosing should be guided by your prenatal care provider. While breastfeeding, iron at appropriate doses is generally considered acceptable—check with your provider on the right amount for you.

Side effects, ingredient by ingredient Black Psyllium Iron Manganese

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Black Psyllium, Manganese, Iron.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 2,044 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take levodopa (Parkinson's medication), quinolone or tetracycline antibiotics, bisphosphonates, levothyroxine (thyroid hormone), methyldopa (blood pressure drug), mycophenolate mofetil (immunosuppressant), penicillamine (copper-chelating drug), or antipsychotic medications. All are affected Moderately by iron or manganese in this powder through reduced absorption, and doses need to be spaced out by at least 2 to 4 hours to minimize the interaction.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is useful if you have iron deficiency anemia or a true manganese deficiency and want both in one powder. The rice protein makes it work as a general protein supplement too.

However, if you take levodopa, antibiotics, thyroid hormone, bisphosphonates, or blood pressure medications, you'll need to separate your doses carefully to avoid reducing how well those drugs work. Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or taking any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rice Protein Powder Plain, straight from the product label.

Brand NutriBiotic
Barcode (UPC) 728177001513
Net contents 48 Ounce(s); 3 Pound(s); 1.36 Kilogram(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 298593
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rice Protein Powder Plain by NutriBiotic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 Gram(s)
Maximum serving Sizes:
15 Gram(s)
Servings per container
90
UPC/BARCODE
728177001513
IngredientAmount% DV
Dietary Fiber1 Gram(s)4%
Protein12 Gram(s)--
Trans Fat0 Gram(s)--
Cholesterol0 mg--
Phosphorus60 mg4%
Iron1 mg6%
Total Fat0 Gram(s)--
Saturated Fat0 Gram(s)--
Calories60 Calorie(s)--
Total Carbohydrate2 Gram(s)1%
Total Sugars1 Gram(s)--
added Sugars0 Gram(s)--
Manganese585 mcg25%

Other ingredients: Rice Protein

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

NutriBiotic Rice Protein is an excellent source of high quality, vegan protein powder providing an extensive array of naturally occurring amino acids, the building blocks of protein.

Formulation

Boosts your nutrition and energy with this wholesome, protein formula! NutriBiotic Rice Protein is produced by means of a unique enzyme process. A proprietary blend of plant enzymes is used to separate the fiber and carbohydrates from the protein portion of the whole grain, brown rice. Due to the enzyme process, color, taste, and texture may vary.

NutriBiotic Rice Protein is made without artificial flavors, artificial sweeteners, artificial colors, chemicals, pesticides, herbicides, PCBs, MSG, preservatives, milk, eggs, soy, yeast, wheat, corn, and nuts.

Gluten & GMO Free

Non-GMO

Gluten free

Vegan

NitroPak: packaged with nitrogen to help retain freshness Not Tested on Animals

We do not use ingredients that were produced using biotechnology.

General Statements

Typical amino acid profile per serving Alanine 690 mg Methionine 345 mg Arginine 975 mg Phenylalanine 660 mg Aspartic acid 1065 mg Proline 555 mg Cystine 270 mg Serine 600 mg Glutamic acid 2160 mg Threonine 435 mg Glycine 540 mg Tryptophan 165 mg Histidine 270 mg Tyrosine 615 mg Isoleucine 525 mg Valine 615 mg Leucine 1035 mg Lysine 360 mg Essential amino acids

Packaging recyclable

Find us on Facebook Instagram Twitter nutribiotic.com

Precautions

Warning: As with any food supplement, you should consult your physician before using this product.

Keep out of reach of children.

If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare practitioner prior to using this product.

California Residents: Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov/food.

Notice: Use this product as a food supplement only. Do not use for weight reduction.

Not intended for children under the age of 7 years.

Brand IP Statement(s)

Copyright 2021 NutriBiotic. All rights reserved

Suggested/Recommended/Usage/Directions

Directions: As a protein source, add one serving to a shaker bottle or glass. Add water, rice milk, or beverage of your choice. Shake or mix well. You may also adda serving to your favorite smoothie or recipe.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rice Protein Powder Plain by NutriBiotic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rice Protein Powder Plain label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rice Protein Powder Plain by NutriBiotic

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 Gram(s) Dosage formPowder Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

12 Gram(s) per serving

Phosphorus

60 mg per serving

Iron

Interacts with
80 drugs
1 mg per serving

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...

Iron monograph & interactions

Manganese

Interacts with
83 drugs
585 mcg per serving

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Other (inactive) ingredients: Rice Protein. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rice Protein Powder Plain by NutriBiotic Drug Interactions

Want to check YOUR meds against Rice Protein Powder Plain?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,043Drugs
145 Moderate 1,898 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Manganese 83
Iron 80

Individual Drug Interactions

The ingredients in Rice Protein Powder Plain interact with 2,043 drugs. Click any drug to see the details.

3 of the 5 ingredients in Rice Protein Powder Plain interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Manganese Iron

Each ingredient & the kinds of drugs it affects

For each ingredient in Rice Protein Powder Plain with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions

Iron13 drug types · 80 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.

Likelihood Probable Evidence D
Bisphosphonates

Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D
Denosumab (Prolia, Others)

Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.

Likelihood Possible Evidence D
Dolutegravir (Tivicay)

Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.

Likelihood Probable Evidence B
Integrase Inhibitors

Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.

Likelihood Possible Evidence D
Levodopa

Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence B
Methyldopa (Aldomet)

Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.

Likelihood Probable Evidence B
Mycophenolate Mofetil (Cellcept)

Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.

Likelihood Unlikely Evidence D
Penicillamine (Cuprimine, Depen)

Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.

Likelihood Probable Evidence D
Quinolone Antibiotics

Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.

Likelihood Probable Evidence D
Chloramphenicol

Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.

Likelihood Unlikely Evidence D
Iron full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rice Protein Powder Plain, from the product label.

NutriBiotic

See all NutriBiotic products
Name
NutriBiotic
City
Lakeport
State
CA
ZipCode
95453
Web Address
nutribiotic.com
Pharmacist Counseling Corner

Rice Protein Powder Plain by NutriBiotic: Common Questions

Does Rice Protein Powder Plain by NutriBiotic interact with any medications?
Yes. Based on its ingredients, Rice Protein Powder Plain has a known interaction with 2,043 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rice Protein Powder Plain contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
Iron in this product is rated Likely Safe during pregnancy and is often recommended, but the dose should be guided by your prenatal care provider. Manganese amounts in prenatal vitamins are fine, but avoid extra high-dose manganese supplements unless your doctor advises it. Talk with your prenatal care provider before starting any new supplement.
Can I take this while breastfeeding?
Iron at appropriate doses is generally considered acceptable while breastfeeding. Manganese safety while breastfeeding is less clear—data shows it could be possibly unsafe or likely unsafe depending on the dose. Check with your doctor or pharmacist to confirm the right dose for you while nursing.
What's the most common side effect I might notice?
If you take this orally, the most common side effects are stomach-related: abdominal pain, constipation, diarrhea, nausea, or vomiting. These usually go away when you adjust the dose or take it with food, but talk with your pharmacist if they persist.
Does this powder actually work for anemia?
Yes—iron in this product is proven effective for iron deficiency anemia and anemia of chronic disease, and it's also effective for pregnancy-related iron deficiency. It's possibly effective for heart failure. But you should only use iron if you actually have low iron or a diagnosed iron deficiency; excess iron can build up in your body and become harmful.
What is manganese in this product supposed to do?
Manganese supports normal bone and connective tissue formation. It's effective for manganese deficiency. Evidence for other uses—hay fever, osteoporosis, COPD, weight loss, and osteoarthritis—is not strong enough to rate. Most people get enough manganese from their diet.
Can high doses of this powder hurt me?
Yes. At high doses over time, iron can accumulate in the body and cause hemochromatosis (too much iron stored in tissues). High-dose manganese can cause serious neurotoxicity and Parkinson-like symptoms. Use this product only at recommended doses and only when there's a real need for iron or manganese supplementation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rice Protein Powder Plain label
Go deeper

The Full Monographs Behind Rice Protein Powder Plain’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Iron

Interacts with 80 drugs

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...

Read the full Iron monograph → Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph →
Sources

Sources & How We Checked

Rice Protein Powder Plain's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 111 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
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Iron 72 references
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See these in context on the Iron monograph →

Manganese 21 references
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See these in context on the Manganese monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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