Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Scale Down Ingredients & Drug Interactions

by DaVinci Laboratories

Scale Down label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Scale Down against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Scale Down is a dietary supplement by DaVinci Laboratories with 2 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Scale Down by DaVinci Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Scale Down by DaVinci Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Scale Down by DaVinci Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Scale Down is a liquid formula with 2 active ingredients. Stevia leaf extract is a natural sweetener derived from the stevia plant.

The product also contains DygloFit, though we have no detailed information on file about its role or properties. The inactive ingredients — glycerin, water, ethyl alcohol, potassium sorbate, and peppermint oil — serve as the liquid base, preservative, and flavoring.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Stevia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Support weight management and satiety.
  • We looked for evidence on: Obesity, Weight loss, Appetite control, Metabolic health.
  • The closest evidence on file: Stevia is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for stevia leaf extract is limited. According to our data, there is insufficient reliable evidence to rate stevia for obesity, hypertension, or diabetes.

While preliminary research suggests a single dose of stevia extract may lower blood sugar after meals in people with type 2 diabetes, other clinical studies have not confirmed a significant blood pressure-lowering effect. We hold no effectiveness ratings for DygloFit.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Stevia leaf extract appears to be well tolerated when taken by mouth. Most minor side effects — such as abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness — seem to resolve after the first week of use.

Serious adverse effects like allergic reactions are rare. Purified stevia in typical food amounts is generally recognized as safe.

However, whole-leaf stevia and supplement doses at higher levels have not been well studied, so caution is advised with longer-term or high-dose use. Pregnancy and lactation safety data are not on file for this product — talk with your doctor or pharmacist for personalized advice if you are pregnant, nursing, or planning pregnancy.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Scale Down, double-check if you use lithium — stevia may raise its levels (Moderate interaction). Also check any blood pressure or diabetes medications you take; stevia may enhance their effects (Minor interactions).

The second ingredient, DygloFit, is something we cannot evaluate for drug interactions because we hold no data on it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Scale Down may be worth considering if you're looking for a stevia-based product, but the evidence for weight or blood sugar benefits is not yet established. If you take lithium, blood pressure medications, or diabetes medications, check with your pharmacist first.

DygloFit is an unknown ingredient to us, so we can't comment on its role or safety profile.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Scale Down, straight from the product label.

Brand DaVinci Laboratories
Barcode (UPC) 026664013347
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 304035
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Scale Down by DaVinci Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
026664013347
IngredientAmount% DV
Stevia Leaf Extract5 mg--
DygloFit200 mg--

Other ingredients: Glycerin, Water, Ethyl Alcohol, Potassium Sorbate, Peppermint Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Color and flavor of this product may vary due to natural variations of the natural ingredients.

A Liquid Dietary Supplement to Support Weight Management and Satiety

Vegetarian

Gluten free Soy free

Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Caution: Product may stain.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

DygloFit is a registered trademark of Gateway Health Alliances, Inc. and is protected under U.S. Patents 8,241, 682 and 8,623,432; and patents pending.

FDA Statement of Identity

A Liquid Dietary Supplement to Support Weight Management and Satiety

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, hold nozzle 1" from mouth, spray five times and swallow. Use once or twice daily or as directed by your healthcare practitioner. Shake well before each use.

FDA Disclaimer Statement

This statement has not been used by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Scale Down by DaVinci Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Scale Down label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Scale Down by DaVinci Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Stevia Leaf Extract

Interacts with
259 drugs
5 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia Leaf Extract monograph & interactions

DygloFit

200 mg per serving Form: Dichrostachys glomerata Fruit Extract

Other (inactive) ingredients: Glycerin, Water, Ethyl Alcohol, Potassium Sorbate, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Scale Down by DaVinci Laboratories Drug Interactions

Want to check YOUR meds against Scale Down?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia Leaf Extract 259

Individual Drug Interactions

The ingredients in Scale Down interact with 259 drugs. Click any drug to see the details.

1 of the 2 ingredients in Scale Down interact with drugs. Each result below shows which ingredient is responsible. Stevia Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Scale Down with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia Leaf Extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Scale Down, from the product label.

DaVinci Laboratories

See all DaVinci Laboratories products
Name
DaVinci Laboratories a division of FoodScience LLC
Street Address
929 Harvest Lane
City
Williston
State
VT
ZipCode
05495
Phone Number
1-800-325-1776
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

Scale Down by DaVinci Laboratories: Common Questions

Does Scale Down by DaVinci Laboratories interact with any medications?
Yes. Based on its ingredients, Scale Down has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Scale Down contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is stevia in this product?
Stevia is a natural sweetener extracted from the stevia plant leaf. It's a common sugar substitute, though in this product the dose is a supplement level rather than typical food amounts.
Will this help me lose weight?
According to the evidence we have on file, there is insufficient reliable evidence to rate stevia for obesity. So we can't confirm whether it works for weight loss.
What side effects might I get?
Most people tolerate it well. The most common minor effects are bloating, dizziness, headache, muscle aches, nausea, and numbness — but these usually go away after the first week. Serious allergic reactions are rare.
Is it safe to take while pregnant or breastfeeding?
Safety data for this product during pregnancy and lactation isn't on file. Talk with your doctor or pharmacist before using it if you're pregnant, nursing, or planning pregnancy — they can give you personalized advice.
I've never heard of DygloFit. What is it?
We don't have detailed information on DygloFit on file, so I can't tell you what it does or how it works in this formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Scale Down is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Scale Down label
Go deeper

The Full Monographs Behind Scale Down’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Scale Down's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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