Berry Essentials Ingredients & Drug Interactions
by IVL Institute for Vibrant Living
What is this page for?
First and foremost: checking Berry Essentials against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Berry Essentials is a dietary supplement by IVL Institute for Vibrant Living with 21 active ingredients. Its ingredients are commonly taken for vitamin c source, immune support, antioxidant support.Based on those ingredients, 1,543 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Green Tea extract, Lycium Fruit, Grape seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Berry Essentials by IVL Institute for Vibrant Living
Ask about any prescription or over-the-counter medication and we check it for interactions with Berry Essentials by IVL Institute for Vibrant Living — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Berry Essentials by IVL Institute for Vibrant Living
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Berry Essentials is a 21-ingredient powder combining whole-fruit and plant extracts. The active ingredients include acerola (high in vitamin C), blackberry, blueberry, black cherry, green tea extract, grape seed extract, mangosteen, tomato powder, black raspberry, cabbage palm fruit, beet powder, black currants, goji fruit, cranberry powder, elderberries, bilberries, camu-camu, purple carrot, banana powder, and guava.
Several of these are rich in antioxidants, polyphenols, or specific compounds like anthocyanins (in berries) and catechins (in green tea). The inactive ingredients include maltodextrin, citric acid, stevia, and natural flavors.
Does it work?
Moderate evidence
Evidence is mixed and often sparse. Green tea extract is likely effective for human papillomavirus (HPV) and possibly effective for ovarian cancer and high cholesterol.
Acerola is possibly effective for vitamin C deficiency but has insufficient evidence for colds, atherosclerosis, or diarrhea. Blueberry is possibly ineffective for high blood pressure but has insufficient evidence for cognitive decline, anxiety, or heart disease.
Beet powder is possibly effective for athletic performance and exercise-induced muscle soreness. Cranberry is possibly effective for urinary tract infections.
Most other ingredients—blackberry, black cherry, mangosteen, tomato, black raspberry, cabbage palm, black currants, goji, elderberries, bilberries, camu-camu, purple carrot, banana, and guava—either lack effectiveness ratings or show insufficient evidence for their advertised uses. This product is not a proven treatment for any specific condition.
How safe is it?
Well-documented data
Most berries and plant powders in this product are generally well tolerated in food amounts. However, concentrated supplements carry less safety data.
Green tea extract in high doses has caused rare liver injury. Acerola may cause allergic reactions (one case of cross-reactivity with latex proteins) and gastrointestinal upset at doses above 2,000 mg daily.
Black cherry contains cyanide-forming compounds and should not be used in large amounts. Elderberry should be properly cooked to remove toxins—raw or unripe berries can cause nausea, vomiting, and severe diarrhea.
Freeze-dried blueberries have caused constipation, diarrhea, nausea, and vomiting; in one trial, 26% of participants dropped out in the first week due to stomach complaints. Banana, carrot, and several other ingredients may trigger allergic reactions in sensitive individuals.
Beet commonly causes red or black stools—this is harmless but can be alarming.
Meds to double-check
Major interaction found
Green tea extract poses Major risks with nadolol and atorvastatin (reduced drug levels). Acerola, goji, cranberry, and grape seed interact Moderately with blood thinners and with drugs metabolized by your liver (especially CYP3A4, CYP2D6, and CYP2C9 enzymes)—affecting statins, heart medications, anxiety drugs, and others.
Blueberry, bilberry, banana, guava, and cabbage palm theoretically increase blood-sugar-lowering effects of diabetes medications. Check with your pharmacist on your specific prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This is a broad antioxidant blend aimed at general wellness, but it's not proven for any specific disease or condition. If you take prescription medications—especially heart drugs, blood thinners, diabetes medications, or seizure medications—talk to your pharmacist before starting.
The green tea extract and goji berry interactions are the biggest red flags. Even if you're generally healthy, check your exact medications with the tool on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 20 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Berry Essentials, straight from the product label.
| Brand | IVL Institute for Vibrant Living |
|---|---|
| Barcode (UPC) | 893320002676 |
| Net contents | 12.45 oz.; 354 g |
| Market status | On market |
| Date entered into DSLD | Aug 24, 2012 |
| DSLD ID | 12119 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Berry Essentials by IVL Institute for Vibrant Living, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Acerola | 350 mg | -- |
| Blackberry | 600 mg | -- |
| Blueberry | 600 mg | -- |
| Black Cherry | 1000 mg | -- |
| Green Tea extract | 50 mg | -- |
| Grape seed extract | 50 mg | -- |
| Mangosteen | 500 mg | -- |
| Tomato powder | 300 mg | -- |
| Black Raspberry | 1000 mg | -- |
| Cabbage Palm Fruit | 1000 mg | -- |
| Beet powder | 600 mg | -- |
| Black Currants | 600 mg | -- |
| Lycium Fruit | 600 mg | -- |
| Cranberry powder | 500 mg | -- |
| Elderberries | 400 mg | -- |
| Bilberries | 350 mg | -- |
| Camu-Camu | 300 mg | -- |
| Purple Carrot | 300 mg | -- |
| Banana powder | 200 mg | -- |
| Fruit & Vegetable Blend | 50 mg | -- |
| Guava | 50 mg | -- |
Other ingredients: Mixed Natural Berry Flavor, Maltodextrin, Citric Acid, Stevia, natural Vanilla flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
(chart) NUTRITION FACTS Serving Size: 1 Scoop (12 g) Servings Per Container: Approx. 30 AMOUNT PER SERVING Calories 45 Calories From Fat 0 % Daily Value Total Fat (g) 0g 0% Saturated Fat 0g 0% Trans Fat 0g 0% Cholesterol 0mg 0% Sodium 15mg 1% Total Carbohydrate 11g 4% Dietary Fiber 0g 0% Sugars 1g Protein 1g Vitamin A 0% Vitamin C 110% Calcium 0% Iron 2%
Before you take any supplement, please consult your physician or other licensed healthcare professional to determine if it's appropriate for you.
HEALTHY GOODNESS AND GREAT TASTE FOR THE WHOLE FAMILY
Brand IP Statement(s)
Berry Essentials(TM) is a tasty alternative to soft drinks that jam-packed with powerful antioxidants to help keep everyone in your family strong, energetic, and healthy.
Precautions
KEEP OUT OF REACH OF CHILDREN
Pregnant or lactating women should consult a healthcare professional prior to use.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
NOT TESTED ON ANIMALS
(recycle) PLEASE RECYCLE
Suggested/Recommended/Usage/Directions
Directions: Mix approximately 1 rounded tablespoon in 6 to 8 ounces of water or your favorite smoothie.
Storage
For maximum freshness refrigerate Berry Essentials(TM) after opening and use within 90 days.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Berry Essentials by IVL Institute for Vibrant Living label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Berry Essentials by IVL Institute for Vibrant Living
These are the 21 active ingredients this product is made of. Select any to open its full monograph.
Serving size12 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Acerola
Interacts with128 drugs
Acerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and an...
Acerola monograph & interactionsBlackberry
No knowninteractions
Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and r...
Blackberry monograph & interactionsBlueberry
Interacts with88 drugs
Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...
Blueberry monograph & interactionsBlack Cherry
Interacts with643 drugs
Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence p...
Black Cherry monograph & interactionsGreen Tea extract
Interacts with1,293 drugs
Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentra...
Green Tea extract monograph & interactionsGrape seed extract
Interacts with910 drugs
Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and b...
Grape seed extract monograph & interactionsMangosteen
Interacts with125 drugs
Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supp...
Mangosteen monograph & interactionsTomato powder
No knowninteractions
Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people...
Tomato powder monograph & interactionsBlack Raspberry
No knowninteractions
Black raspberry is a nutrient-rich fruit packed with antioxidants like anthocyanins and ellagic acid, and as a food it is generally safe and healthy....
Black Raspberry monograph & interactionsCabbage Palm Fruit
Interacts with325 drugs
Cabbage is a nutritious, low-calorie vegetable that is safe to eat as food and is sometimes applied to the skin as a leaf wrap for breast engorgement...
Cabbage Palm Fruit monograph & interactionsBeet powder
Interacts with861 drugs
Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...
Beet powder monograph & interactionsBlack Currants
Interacts with140 drugs
Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjo...
Black Currants monograph & interactionsLycium Fruit
Interacts with1,000 drugs
Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they...
Lycium Fruit monograph & interactionsCranberry powder
Interacts with712 drugs
Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...
Cranberry powder monograph & interactionsElderberries
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Elderberries monograph & interactionsBilberries
Interacts with275 drugs
Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...
Bilberries monograph & interactionsCamu-Camu
No knowninteractions
Camu camu is an Amazonian berry that is very high in vitamin C and plant antioxidants, which is why it is popular as an immune and antioxidant supplem...
Camu-Camu monograph & interactionsPurple Carrot
No knowninteractions
Carrot is a common food vegetable that is a rich source of beta-carotene (which the body turns into vitamin A) and other nutrients. Eating carrots is...
Purple Carrot monograph & interactionsBanana powder
Interacts with5 drugs
Bananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While s...
Banana powder monograph & interactionsFruit & Vegetable Blend
Guava
Interacts with86 drugs
Guava is a tropical fruit tree whose leaves and fruit have a long history of folk use for diarrhea, blood sugar, and general wellness. The fruit is a...
Guava monograph & interactionsOther (inactive) ingredients: Mixed Natural Berry Flavor, Maltodextrin, Citric Acid, Stevia, Natural Vanilla flavor. These complete the product’s ingredient list but are not active constituents.
Berry Essentials by IVL Institute for Vibrant Living Drug Interactions
HelloPharmacist Interaction Report
Berry Essentials by IVL Institute for Vibrant Living contains several ingredients with documented interactions with medications.
The most serious concern is green tea extract, which carries Major-severity interactions with nadolol (a heart medication) and atorvastatin (a cholesterol drug)—both can lose effectiveness by up to 85% when combined with this ingredient.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions span multiple drug categories. Acerola (vitamin C) may reduce the effectiveness of chemotherapy drugs like alkylating agents and antitumor antibiotics.
Green tea extract also theoretically reduces the effects of seizure medications (felbamate, valproate, ethosuximide, phenytoin) due to its caffeine content. Additionally, grape seed extract, goji berry, cranberry powder, and several other ingredients interact with blood thinners and drugs metabolized by liver enzymes (CYP3A4, CYP2D6, and others), potentially affecting medications for cholesterol, heart rhythm, anxiety, and pain.
Although some ingredients like blueberry and bilberry carry minor interactions with diabetes drugs and anti-inflammatory medications, and several berries theoretically increase bleeding risk with anticoagulants, the overall pattern is dominated by liver-metabolism effects. Altogether, these interactions span 1,521 individual medications.
We could not check Fruit & Vegetable Blend—no data is on file for it. Before you start this product, search your exact medications with the tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Berry Essentials?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Berry Essentials interact with 1,543 drugs. Click any drug to see the details.
15 of the 21 ingredients in Berry Essentials interact with drugs. Each result below shows which ingredient is responsible. Green Tea extract Lycium Fruit Grape seed extract Beet powder Cranberry powder Black Cherry Cabbage Palm Fruit Bilberries Black Currants Acerola Mangosteen Elderberries Blueberry Guava Banana powder
Aminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractEphedrine, Stimulant Drugs Major
Interaction Summary
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Read the full Green Tea Extract + Aminophylline, Amobarbital, Ephedrine interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Berry Essentials — through 7 ingredients. Tap an ingredient for the detail:
Green Tea ExtractAtorvastatin (lipitor), Cytochrome P450 3a4 (cyp3a4) Substrates +2 Major
Interaction Summary
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
Read the full Green Tea Extract + Atorvastatin interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Atorvastatin interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Atorvastatin interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Atorvastatin interactionCranberry PowderAtorvastatin (lipitor), Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
Read the full Cranberry Powder + Atorvastatin interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Atorvastatin interactionCabbage Palm FruitGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Cabbage Palm Fruit + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Berry Essentials — through 7 ingredients. Tap an ingredient for the detail:
Green Tea ExtractAtorvastatin (lipitor), Organic Anion-transporting Polypeptide Substrates (oatp) +2 Major
Interaction Summary
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
Read the full Green Tea Extract + Atorvastatin Calcium interactionCabbage Palm FruitGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Cabbage Palm Fruit + Atorvastatin Calcium interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Atorvastatin Calcium interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Atorvastatin Calcium interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Atorvastatin Calcium interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates, Atorvastatin (lipitor) Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Atorvastatin Calcium interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Atorvastatin Calcium interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Berry Essentials — through 3 ingredients. Tap an ingredient for the detail:
Green Tea ExtractDiuretic Drugs, Nadolol (corgard) Major
Interaction Summary
Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.
Read the full Green Tea Extract + Bendroflumethiazide, Nadolol interactionLycium FruitAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Read the full Lycium Fruit + Bendroflumethiazide, Nadolol interactionBeet PowderAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Powder + Bendroflumethiazide, Nadolol interactionCarbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine TannateQuadratuss, Ry Tuss, Rynatuss, Tri Tannate Plus
How Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Ephedrine +1 Major
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionDyphylline, Ephedrine, Guaifenesin, PhenobarbitalLufyllin-EPG
How Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractPhenobarbital (luminal), Ephedrine +1 Major
Interaction Summary
Theoretically, green tea might reduce the effects of phenobarbital and increase the risk for convulsions.
Read the full Green Tea Extract + Dyphylline, Ephedrine, Guaifenesin, Phenobarbital interactionEphedrine, Guaifenesin (otc Drug)Ephedrine Formula 400, Ephedrine Plus Tabs
How Ephedrine, Guaifenesin (otc Drug) interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Ephedrine Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Guaifenesin (otc Drug) interactionEphedrine, Guaifenesin, Phenobarbital, TheophyllineMudrane GG
How Ephedrine, Guaifenesin, Phenobarbital, Theophylline interacts with Berry Essentials — through 4 ingredients. Tap an ingredient for the detail:
Green Tea ExtractPhenobarbital (luminal), Ephedrine +2 Major
Interaction Summary
Theoretically, green tea might reduce the effects of phenobarbital and increase the risk for convulsions.
Read the full Green Tea Extract + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionCabbage Palm FruitCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, cabbage might decrease levels of drugs metabolized by CYP1A2.
Read the full Cabbage Palm Fruit + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionGrape Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Extract + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionBeet PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Powder + Ephedrine, Guaifenesin, Phenobarbital, Theophylline interactionEphedrine, Hydroxyzine, TheophyllineAmi Rax, Marax
How Ephedrine, Hydroxyzine, Theophylline interacts with Berry Essentials — through 4 ingredients. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Theophylline +1 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Hydroxyzine, Theophylline interactionGrape Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
Read the full Grape Seed Extract + Ephedrine, Hydroxyzine, Theophylline interactionCabbage Palm FruitCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, cabbage might decrease levels of drugs metabolized by CYP1A2.
Read the full Cabbage Palm Fruit + Ephedrine, Hydroxyzine, Theophylline interactionBeet PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Powder + Ephedrine, Hydroxyzine, Theophylline interactionEphedrine, Phenobarbital, Potassium Iodide, TheophyllineMudrane, Quadrinal
How Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractPhenobarbital (luminal), Ephedrine +2 Major
Interaction Summary
Theoretically, green tea might reduce the effects of phenobarbital and increase the risk for convulsions.
Read the full Green Tea Extract + Ephedrine, Phenobarbital, Potassium Iodide, Theophylline interactionEphedrine, Phenobarbital, TheophyllineTedral
How Ephedrine, Phenobarbital, Theophylline interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractStimulant Drugs, Theophylline +2 Major
Interaction Summary
Theoretically, concomitant use might increase stimulant adverse effects.
Read the full Green Tea Extract + Ephedrine, Phenobarbital, Theophylline interactionEzetimibe, AtorvastatinLiptruzet
How Ezetimibe, Atorvastatin interacts with Berry Essentials — through 7 ingredients. Tap an ingredient for the detail:
Green Tea ExtractAtorvastatin (lipitor), Organic Anion-transporting Polypeptide Substrates (oatp) +2 Major
Interaction Summary
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
Read the full Green Tea Extract + Ezetimibe, Atorvastatin interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Ezetimibe, Atorvastatin interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Ezetimibe, Atorvastatin interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates, Atorvastatin (lipitor) Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Ezetimibe, Atorvastatin interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Ezetimibe, Atorvastatin interactionCabbage Palm FruitGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Cabbage Palm Fruit + Ezetimibe, Atorvastatin interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Ezetimibe, Atorvastatin interactionNadololCorgard, Nadolol
How Nadolol interacts with Berry Essentials — through 3 ingredients. Tap an ingredient for the detail:
Green Tea ExtractNadolol (corgard) Major
Interaction Summary
Green tea seems to reduce the levels and clinical effects of nadolol.
Read the full Green Tea Extract + Nadolol interactionLycium FruitAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Read the full Lycium Fruit + Nadolol interactionBeet PowderAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Powder + Nadolol interactionWarfarinWarfarin
How Warfarin interacts with Berry Essentials — through 11 ingredients. Tap an ingredient for the detail:
Lycium FruitWarfarin (coumadin), Cytochrome P450 2c19 (cyp2c19) Substrates +2 Major
Interaction Summary
Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
Read the full Lycium Fruit + Warfarin interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Warfarin interactionCranberry PowderWarfarin (coumadin), Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of warfarin.
Read the full Cranberry Powder + Warfarin interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Warfarin interactionGrape Seed ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Grape Seed Extract + Warfarin interactionCabbage Palm FruitWarfarin (coumadin), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, cabbage might decrease the anticoagulant effects of warfarin.
Read the full Cabbage Palm Fruit + Warfarin interactionBilberriesAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberries + Warfarin interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Warfarin interactionBlack CurrantsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currants + Warfarin interactionMangosteenAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Warfarin interactionAcerolaWarfarin (coumadin) Minor
Interaction Summary
Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Berry Essentials — through 11 ingredients. Tap an ingredient for the detail:
Lycium FruitCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +2 Major
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Warfarin Sodium interactionGreen Tea ExtractWarfarin (coumadin), Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with warfarin.
Read the full Green Tea Extract + Warfarin Sodium interactionGrape Seed ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
Read the full Grape Seed Extract + Warfarin Sodium interactionCranberry PowderWarfarin (coumadin), Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of warfarin.
Read the full Cranberry Powder + Warfarin Sodium interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Warfarin Sodium interactionMangosteenAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Warfarin Sodium interactionBlack CurrantsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currants + Warfarin Sodium interactionBeet PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Powder + Warfarin Sodium interactionCabbage Palm FruitWarfarin (coumadin), Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, cabbage might decrease the anticoagulant effects of warfarin.
Read the full Cabbage Palm Fruit + Warfarin Sodium interactionBilberriesAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberries + Warfarin Sodium interactionAcerolaWarfarin (coumadin) Minor
Interaction Summary
Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola + Warfarin Sodium interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Berry Essentials — through 2 ingredients. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + 6-mercaptopurine interactionElderberriesImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberries + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Grape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Ado-trastuzumab Emtansine interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Ado-trastuzumab Emtansine interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Ado-trastuzumab Emtansine interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Ado-trastuzumab Emtansine interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Ado-trastuzumab Emtansine interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abacavir, Lamivudine interactionAbametapirXeglyze
How Abametapir interacts with Berry Essentials — through 1 ingredient. Tap an ingredient for the detail:
Green Tea ExtractCytochrome P450 1a2 (cyp1a2) Inhibitors Moderate
Interaction Summary
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Read the full Green Tea Extract + Abametapir interactionAbciximabReoPro
How Abciximab interacts with Berry Essentials — through 5 ingredients. Tap an ingredient for the detail:
Grape Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Grape Seed Extract + Abciximab interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Abciximab interactionBilberriesAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberries + Abciximab interactionBlack CurrantsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currants + Abciximab interactionMangosteenAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Lycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Abemaciclib interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Abemaciclib interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Abemaciclib interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Abemaciclib interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Abemaciclib interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Black CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Abiraterone interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Abiraterone interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Inhibitors +1 Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Abiraterone interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Abiraterone interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Abiraterone interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Beet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Abiraterone Acetate interactionGrape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Abiraterone Acetate interactionGreen Tea ExtractHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Abiraterone Acetate interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Abiraterone Acetate interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Abiraterone Acetate interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Berry Essentials — through 8 ingredients. Tap an ingredient for the detail:
MangosteenAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Abrocitinib interactionBlack CurrantsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currants + Abrocitinib interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Abrocitinib interactionGrape Seed ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
Read the full Grape Seed Extract + Abrocitinib interactionElderberriesImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberries + Abrocitinib interactionLycium FruitCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
Read the full Lycium Fruit + Abrocitinib interactionBilberriesAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberries + Abrocitinib interactionCranberry PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
Grape Seed ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
Read the full Grape Seed Extract + Acalabrutinib interactionBeet PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Powder + Acalabrutinib interactionLycium FruitCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
Read the full Lycium Fruit + Acalabrutinib interactionGreen Tea ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Green tea is unlikely to produce clinically significant changes in the levels and clinical effects of CYP3A4 substrates.
Read the full Green Tea Extract + Acalabrutinib interactionBlack CherryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes.
Read the full Black Cherry + Acalabrutinib interactionCranberry PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
Read the full Cranberry Powder + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Berry Essentials — through 6 ingredients. Tap an ingredient for the detail:
GuavaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use with antidiabetes drugs might have additive effects and increase the risk of hypoglycemia.
Read the full Guava + Acarbose interactionBilberriesAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Bilberries + Acarbose interactionCabbage Palm FruitAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cabbage Palm Fruit + Acarbose interactionGreen Tea ExtractHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acarbose interactionBlueberryAntidiabetes Drugs Minor
Interaction Summary
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Blueberry + Acarbose interactionLycium FruitAntidiabetes Drugs Minor
Interaction Summary
Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Read the full Lycium Fruit + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Berry Essentials — through 3 ingredients. Tap an ingredient for the detail:
Green Tea ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full Green Tea Extract + Acebutolol interactionLycium FruitAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Read the full Lycium Fruit + Acebutolol interactionBeet PowderAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Powder + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Berry Essentials — through 5 ingredients. Tap an ingredient for the detail:
BilberriesAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberries + Acenocoumarol interactionGreen Tea ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Green Tea Extract + Acenocoumarol interactionMangosteenAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen + Acenocoumarol interactionBlack CurrantsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Read the full Black Currants + Acenocoumarol interactionGrape Seed ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Grape Seed Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Berry Essentials — through 2 ingredients. Tap an ingredient for the detail:
Black CurrantsPhenothiazines Moderate
Interaction Summary
Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.
Read the full Black Currants + Acepromazine interactionGreen Tea ExtractPhenothiazines Minor
Interaction Summary
Theoretically, phenothiazines might increase the levels and adverse effects of caffeine.
Read the full Green Tea Extract + Acepromazine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Berry Essentials with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Green Tea extract
Atorvastatin (Lipitor)
Green tea extract seems to reduce the levels and clinical effects of atorvastatin.
In healthy humans, taking green tea extract 300 mg or 600 mg along with atorvastatin reduces plasma levels of atorvastatin by approximately 24%. The elimination of atorvastatin is not affected. Atorvastatin is a substrate of organic anion-transporting polypeptides (OATPs). Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs. Some OATPs are expressed in the small intestine and are responsible for the uptake of drugs and other compounds, which may have resulted in reduced plasma levels of atorvastatin. It is not clear if drinking green tea alters the absorption of atorvastatin.
Ephedrine
Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Green tea contains caffeine. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.
Nadolol (Corgard)
Green tea seems to reduce the levels and clinical effects of nadolol.
Preliminary clinical research shows that green tea consumption reduces plasma concentrations of nadolol. Compared to a control group, both peak levels and total drug exposure (AUC) of nadolol were reduced by approximately 85% in subjects who drank green tea daily for two weeks. Drinking green tea with nadolol also significantly reduced nadolol's systolic blood pressure lowering effect. Other clinical research shows that a single dose of green tea can affect plasma nadolol levels for at least one hour. Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is involved in the uptake of nadolol in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
5-Fluorouracil
Theoretically, high doses of green tea might increase the effects and side effects of 5-fluorouracil.
Animal research shows that taking green tea in amounts equivalent to about 6 cups daily in humans for 4 weeks prior to receiving a single injection of 5-fluorouracil increases the maximum plasma levels of 5-fluorouracil by about 2.5-fold and the area under the curve by 425%.
Adenosine (Adenocard)
Theoretically, green tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine is a competitive inhibitor of adenosine at the cellular level. However, caffeine doesn't seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Anticoagulant/Antiplatelet Drugs
Theoretically, green tea may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Conflicting reports exist regarding the effect of green tea on bleeding risk when used with anticoagulant or antiplatelet drugs; however, most evidence suggests that drinking green tea in moderate amounts is unlikely to cause a significant interaction. Green tea contains small amounts of vitamin K, approximately 7 mcg per cup. Some case reports have associated the antagonism of warfarin with the vitamin K content of green tea. However, these reports are rare, and very large doses of green tea (about 8-16 cups daily) appear to be needed to cause these effects. Furthermore, the catechins and caffeine in green tea are reported to have antiplatelet activity.
Beta-Adrenergic Agonists
Green tea contains caffeine. Theoretically, concomitant use of large amounts of caffeine might increase cardiac inotropic effects of beta-agonists.
Bortezomib (Velcade)
Theoretically, green tea might interfere with the effects of bortezomib.
In vitro research shows that green tea polyphenols, such as epigallocatechin gallate (EGCG), interact with bortezomib and block its proteasome inhibitory action. This prevents the induction of cell death in multiple myeloma or glioblastoma cancer cell lines. Advise patients taking bortezomib, not to take green tea.
Carbamazepine (Tegretol)
Theoretically, green tea might reduce the effects of carbamazepine and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.
Celiprolol (Celicard)
Theoretically, green tea might reduce the levels and clinical effects of celiprolol.
In a small human study, taking green tea daily for 4 days appears to decrease blood and urine levels of celiprolol by at least 98%. This interaction is possibly due to the inhibition of organic anion transporting polypeptide (OATP). Green tea catechins have been shown to inhibit organic anion transporting polypeptides (OATP), one of which, OATP1A2, is found in the intestine The interaction is thought to be due primarily to the epigallocatechin gallate (EGCG) content of green tea.
Cimetidine (Tagamet)
Theoretically, concomitant use might increase the effects and adverse effects of caffeine in green tea.
Green tea contains caffeine. Cimetidine can reduce caffeine clearance by 31% to 42%.
Clozapine (Clozaril)
Theoretically, green tea might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Animal research suggests that, although green tea extract does not affect the elimination of clozapine, it delays the time to reach peak concentration and reduces the peak plasma levels. Also, concomitant administration of green tea and clozapine might theoretically cause acute exacerbation of psychotic symptoms due to the caffeine in green tea. Caffeine can increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg daily inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Researchers speculate that caffeine might inhibit CYP1A2. However, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients be more sensitive to the interaction between clozapine and caffeine.
Contraceptive Drugs
Theoretically, concomitant use might increase the effects and adverse effects of caffeine found in green tea.
Green tea contains caffeine. Oral contraceptives can decrease caffeine clearance by 40% to 65%.
Cytochrome P450 1A2 (Cyp1A2) Inhibitors
Theoretically, concomitant use might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Caffeine is metabolized by cytochrome P450 1A2 (CYP1A2),. Theoretically, drugs that inhibit CYP1A2 may decrease the clearance rate of caffeine from green tea and increase caffeine levels.
Dipyridamole (Persantine)
Theoretically, green tea might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Green tea contains caffeine. Caffeine might inhibit dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.
Disulfiram (Antabuse)
Theoretically, disulfiram might increase the risk of adverse effects from caffeine.
In human research, disulfiram decreases the clearance and increases the half-life of caffeine.
Diuretic Drugs
Theoretically, using green tea with diuretic drugs might increase the risk of hypokalemia.
Green tea contains caffeine. In excessive amounts, caffeine can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.
Estrogens
Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Estrogen inhibits caffeine metabolism.
Ethosuximide (Zarontin)
Theoretically, green tea might reduce the effects of ethosuximide and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.
Felbamate (Felbatol)
Theoretically, green tea might reduce the effects of felbamate and increase the risk for convulsions.
Green tea contains caffeine. Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.
Fexofenadine (Allegra)
Green tea can decrease blood levels of fexofenadine.
Clinical research shows that green tea can significantly decrease blood levels and excretion of fexofenadine. Taking green tea extract with a dose of fexofenadine decreased bioavailability of fexofenadine by about 30%. In vitro, green tea inhibits the cellular accumulation of fexofenadine by inhibiting the organic anion transporting polypeptide (OATP) drug transporter. Research shows that two of the major catechins found in green tea, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), inhibit OATPs, specifically OATP1A2, OATP1B1, and OATP2B1. In addition, green tea has been shown to reduce the absorption of some drugs that are OATP substrates.
Flutamide (Eulexin)
Theoretically, green tea might increase the levels and adverse effects of flutamide.
Green tea contains caffeine. In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. Theoretically, concomitant use of caffeine and flutamide might increase serum concentrations of flutamide and increase the risk adverse effects.
Fluvoxamine (Luvox)
Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Green tea contains caffeine. Fluvoxamine reduces caffeine metabolism.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Green tea extract supplements have been linked to several cases of hepatotoxicity and might have additive hepatotoxic effects with other drugs..
Imatinib (Gleevec)
Theoretically, green tea might reduce the levels and clinical effects of imatinib.
In animal research, a single dose of green tea extract reduces the area under the curve (AUC) of imatinib by up to approximately 64% and its main metabolite N-desmethyl imatinib by up to approximately 81%. This interaction has not been shown in humans. The mechanism of action is unclear but may involve multiple pathways.
Lycium Fruit
Warfarin (Coumadin)
Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
There are at least 5 case reports of increased international normalized ratio (INR) in patients stabilized on warfarin who began drinking goji juice, concentrated goji tea, or goji wine. Goji may inhibit the metabolism of warfarin by cytochrome P450 2C9 (CYP2C9).
Antihypertensive Drugs
Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Animal and in vitro research suggest that goji root bark has hypotensive effects. However, goji fruit juice does not appear to reduce systolic or diastolic blood pressure in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, goji berry might inhibit CYP2C19 and reduce metabolism of CYP2C19 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C19 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2C19 substrates. However, this has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C9 enzymes. Additionally, multiple case reports suggest that goji berry concentrated tea and juice inhibit the metabolism of warfarin, a CYP2C9 substrate. Concomitant use with goji may decrease metabolism and increase levels of CYP2C9 substrates.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
In vitro research shows that goji berry juice inhibits CYP2D6 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2D6 substrates. However, this has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
In vitro research shows that goji berry juice inhibits CYP3A4 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP3A4 substrates. However, this has not been reported in humans.
Flecainide (Tambocor)
Theoretically, goji berry might increase the levels and clinical effects of flecainide.
In one case report, a 75-year-old patient stable on flecainide and warfarin presented to the emergency room with fainting and pleomorphic arrhythmia caused by flecainide toxicity. Flecainide toxicity was attributed to drinking 1-2 glasses of concentrated goji tea daily for 2 weeks. Theoretically, goji may have inhibited the cytochrome P450 2D6 (CYP2D6) metabolism of flecainide.
Antidiabetes Drugs
Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Animal and in vitro research show that goji root bark and fruit polysaccharides might have hypoglycemic effects. However, clinical research has only shown that taking goji fruit polysaccharides with or without antidiabetes drugs modestly reduces postprandial glucose when compared with control, with no reports of hypoglycemia.
Grape seed extract
Anticoagulant/Antiplatelet Drugs
Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.
Cyclosporine (Neoral, Sandimmune)
Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.
Midazolam (Versed)
Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.
Phenacetin
Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).
Cytochrome P450 2C9 (Cyp2C9) Substrates
It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.
Beet powder
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.
Antihypertensive Drugs
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.
Cranberry powder
Atorvastatin (Lipitor)
Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.
Nifedipine (Procardia)
Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.
Warfarin (Coumadin)
Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.
Diclofenac (Voltaren, Others)
Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.
Black Cherry
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.
Cabbage Palm Fruit
Acetaminophen (Tylenol, Others)
Cabbage might increase clearance and reduce the effects of acetaminophen.
A small clinical study shows that daily consumption of cabbage and Brussels sprout decreases acetaminophen levels by as much as 16%, with some evidence suggesting that this effect is due to increased elimination through glucuronide conjugation.
Antidiabetes Drugs
Theoretically, cabbage might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vivo research suggests that cabbage might have hypoglycemic effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, cabbage might decrease levels of drugs metabolized by CYP1A2.
Some animal research suggests that cabbage or its constituent indole-3-carbinol might increase drug metabolism and elimination by stimulating CYP1A2 activity.
Glucuronidated Drugs
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
A small clinical study shows that daily consumption of cabbage and Brussels sprout decreases levels of some drugs metabolized through glucuronide conjugation.
Oxazepam (Serax)
Cabbage might increase clearance and reduce the effects of oxazepam.
A small clinical study shows that daily consumption of cabbage and brussels sprout decreases oxazepam levels by as much as 17%, with some evidence suggesting that this effect is due to increased elimination through glucuronide conjugation.
Warfarin (Coumadin)
Theoretically, cabbage might decrease the anticoagulant effects of warfarin.
Cabbage contains vitamin K. If consumed in large quantities, cabbage might decrease the anticoagulant effects of warfarin.
Bilberries
Anticoagulant/Antiplatelet Drugs
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.
Erlotinib (Tarceva)
Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.
Black Currants
Anticoagulant/Antiplatelet Drugs
Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Gamma-linolenic acid (GLA), a constituent of black currant seed oil, appears to have antiplatelet effects.
Phenothiazines
Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.
Black currant seed oil contains gamma-linolenic acid (GLA). There is some concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines, although there is no evidence that black currant seed oil causes seizures. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with GLA, although none experienced an actual seizure. In another report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily, which contains GLA, was added. One of these patients had a prior history of seizures.
Acerola
Alkylating Agents
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as alkylating agents. In contrast, other researchers theorize that antioxidants might make alkylating chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Antitumor Antibiotics
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.
Aluminum
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Acerola contains vitamin C. It is thought that vitamin C chelates aluminum, keeping it in solution and available for absorption. In people with normal renal function, urinary excretion of aluminum likely increases, making aluminum retention and toxicity unlikely. However, patients with renal failure who take aluminum-containing compounds, such as phosphate binders, should avoid acerola in doses that provide more vitamin C than the recommended dietary allowances.
Aspirin
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and aspirin is unlikely.
Estrogens
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Acerola contains vitamin C. Increases in plasma estrogen levels of up to 55% have occurred under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.
Warfarin (Coumadin)
Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and warfarin is unlikely.
Mangosteen
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
In vitro and animal research shows that gamma-mangostin, a constituent of mangosteen, is a potent and competitive antagonist of the serotonin 2A (5-HT2A) receptor. Antagonism of the 5-HT2A receptor is believed to reduce platelet aggregation.
Donepezil (Aricept)
Theoretically, concomitant use of mangosteen with donepezil might increase the effects of donepezil.
Animal research shows that concomitant use of an aqueous extract of mangosteen pericarp with donepezil increases brain concentrations of donepezil at 4 hours by 64% without associated effects on systemic exposure.
Elderberries
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Blueberry
Antidiabetes Drugs
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.
Buspirone (Buspar)
Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.
Flurbiprofen (Ansaid, Others)
Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.
Guava
Antidiabetes Drugs
Theoretically, concomitant use with antidiabetes drugs might have additive effects and increase the risk of hypoglycemia. Animal research shows that guava leaf extract or guava fruit can have hypoglycemic effects. Monitor blood glucose levels closely. Medication dose adjustments may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, metformin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Banana powder
Levodopa
Taking banana may reduce the effectiveness of levodopa.
A case report describes apparent wearing off in a patient with Parkinson disease after eating a banana every day. The wearing off subsided after removing dietary bananas.
Brand information
Manufacturer and brand details for Berry Essentials, from the product label.
IVL Institute for Vibrant Living
- Name
- Institute For Vibrant Living
- Street Address
- P.O. Box 3840
- City
- Camp Verde
- State
- AZ
- ZipCode
- 86322
Berry Essentials by IVL Institute for Vibrant Living: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Berry Essentials’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Acerola
Interacts with 128 drugsAcerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and antioxidants. While vitamin C itself has w...
Read the full Acerola monograph → Herb & supplement monographBlackberry
Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional u...
Read the full Blackberry monograph → Herb & supplement monographBlueberry
Interacts with 88 drugsBlueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...
Read the full Blueberry monograph → Herb & supplement monographWild Cherry
Interacts with 643 drugsWild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...
Read the full Wild Cherry monograph → Herb & supplement monographGreen Tea
Interacts with 1,293 drugsGreen tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentrated green tea extracts are a different s...
Read the full Green Tea monograph → Herb & supplement monographGrape
Interacts with 910 drugsGrapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...
Read the full Grape monograph → Herb & supplement monographMangosteen
Interacts with 125 drugsMangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supplements for inflammation, immune support...
Read the full Mangosteen monograph → Herb & supplement monographTomato
Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...
Read the full Tomato monograph → Herb & supplement monographBlack Raspberry
Black raspberry is a nutrient-rich fruit packed with antioxidants like anthocyanins and ellagic acid, and as a food it is generally safe and healthy. Some early research explores it for canc...
Read the full Black Raspberry monograph → Herb & supplement monographCabbage
Interacts with 325 drugsCabbage is a nutritious, low-calorie vegetable that is safe to eat as food and is sometimes applied to the skin as a leaf wrap for breast engorgement or sore joints. Most medicinal claims ar...
Read the full Cabbage monograph → Herb & supplement monographBeet
Interacts with 861 drugsBeet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...
Read the full Beet monograph → Herb & supplement monographBlack Currant
Interacts with 140 drugsBlack currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjoyed safely as a food and is popular as a...
Read the full Black Currant monograph → Herb & supplement monographGoji
Interacts with 1,000 drugsGoji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they are popular for eye health, immune supp...
Read the full Goji monograph → Herb & supplement monographCranberry
Interacts with 712 drugsCranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...
Read the full Cranberry monograph → Herb & supplement monographElderberry
Interacts with 121 drugsElderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...
Read the full Elderberry monograph → Herb & supplement monographBilberry
Interacts with 275 drugsBilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...
Read the full Bilberry monograph → Herb & supplement monographCamu Camu
Camu camu is an Amazonian berry that is very high in vitamin C and plant antioxidants, which is why it is popular as an immune and antioxidant supplement. Human research is still limited, so...
Read the full Camu Camu monograph → Herb & supplement monographCarrot
Carrot is a common food vegetable that is a rich source of beta-carotene (which the body turns into vitamin A) and other nutrients. Eating carrots is safe and nutritious for most people, but...
Read the full Carrot monograph → Herb & supplement monographBanana
Interacts with 5 drugsBananas are a nutritious, widely eaten fruit that provide potassium, fiber, vitamin B6, and quick energy, and they are part of a healthy diet. While some traditional uses (like easing diarrh...
Read the full Banana monograph → Herb & supplement monographGuava
Interacts with 86 drugsGuava is a tropical fruit tree whose leaves and fruit have a long history of folk use for diarrhea, blood sugar, and general wellness. The fruit is a nutritious food rich in vitamin C, but e...
Read the full Guava monograph →Sources & How We Checked
Berry Essentials's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 434 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Acerola 20 references
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
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