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Dietary supplement

Shilajit 500 mg Ingredients & Drug Interactions

by youtheory

Shilajit 500 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shilajit 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shilajit 500 mg is a dietary supplement by youtheory with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, male fertility and testosterone support, general vitality and aging.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shilajit. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Shilajit 500 mg by youtheory

Ask about any prescription or over-the-counter medication and we check it for interactions with Shilajit 500 mg by youtheory — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Shilajit 500 mg by youtheory

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Youtheory Shilajit 500 mg is a single-ingredient supplement containing shilajit, a mineral-rich substance traditionally used in Ayurvedic medicine. The capsule also contains inactive ingredients (vegetable cellulose, microcrystalline cellulose, vegetable magnesium stearate, croscarmellose sodium, and silicon dioxide), which are fillers and binders that help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Shilajit's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: adaptogen supporting energy and stress response.
  • We looked for evidence on: Athletic performance, Male infertility, fatigue, cognitive function, aging.
  • The closest evidence on file: Shilajit is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Shilajit is rated "Insufficient Reliable Evidence To Rate" for Male infertility.

The evidence isn't established for shilajit in the data we hold. For Alzheimer disease, sexual dysfunction, athletic performance, benign prostatic hyperplasia (enlarged prostate), and osteoporosis (weak bones), there is insufficient reliable evidence to rate its effectiveness.

Before using this product for any specific health goal, talk with your doctor or pharmacist about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Shilajit

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Shilajit is generally well tolerated, though a small number of cases have been reported: one person developed an allergic reaction (hives and anaphylaxis) at a higher dose, and headache has been reported rarely in clinical research. A case of high blood pressure linked to mineral imbalance was reported in a pregnant person; the role of shilajit couldn't be confirmed, but it raises concern.

The safety data advises against shilajit during pregnancy and while breastfeeding. Additionally, unpurified shilajit may contain heavy metals or other contaminants—use only purified, tested brands.

Side effects, ingredient by ingredient Shilajit

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Shilajit.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, glibenclamide, or others), check with your doctor or pharmacist before adding shilajit—the combination could lower your blood sugar too much. No other medication interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Youtheory Shilajit 500 mg may be considered by people looking for a traditional mineral supplement, but it's not right for anyone on diabetes medication without a conversation first. Pregnant people and those breastfeeding should avoid it.

Talk with your own doctor or pharmacist before starting it, especially if you take any prescription drugs or have diabetes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shilajit 500 mg, straight from the product label.

Brand youtheory
Barcode (UPC) 850502007577
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 253064
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shilajit 500 mg by youtheory, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
850502007577
IngredientAmount% DV
Shilajit500 mg--

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Powerful adaptogen Supports the body during stress Enhances mitochondrial function & energy Boosts collagen production

Boosts energy

Shilajit Country of Origin: India

Formula

Shilajit (shee-la-jeet) is one of the great wonders of Ayurveda. Rich in minerals and nutrients, this revitalizing superfood is sourced from deep within the Himalayan mountains. While authentic shilajit is rare, Youtheory Shilajit is made with PrimaVie - a patented authentic extract that is clinically tested for maximum effectiveness.

500 mg of Shilajit per daily serving.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take two (2) capsules per day with a glass of water.

Precautions

This product is manufactured in a facility that processes whey milk protein and fish extracts.

Usage Warnings: Check with your doctor before using this product if you are taking medication or have any medical conditions. Do not use if you are pregnant or nursing.

Do not exceed the recommended daily intake.

Not intended for persons under 18. Keep out of reach of children.

Warning: Consuming this product can expose you to lead, a chemical known to the State of California to cause reproductive harm. For more information, go to www.P65Warnings.ca.gov.

Brand IP Statement(s)

PrimaVie is a registered trademark of Natreon, Inc.

Storage

Store in a cool and dry place after opening.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shilajit 500 mg by youtheory label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shilajit 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shilajit 500 mg by youtheory

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Shilajit

Interacts with
86 drugs
500 mg per serving

Shilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and v...

Shilajit monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Croscarmellose Sodium, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Shilajit 500 mg by youtheory Drug Interactions

Want to check YOUR meds against Shilajit 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Shilajit 86

Individual Drug Interactions

The ingredients in Shilajit 500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Shilajit 500 mg interact with drugs. Each result below shows which ingredient is responsible. Shilajit

Each ingredient & the kinds of drugs it affects

For each ingredient in Shilajit 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Shilajit1 drug type · 86 drugs

Antidiabetes Drugs

Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Most human and animal research shows that shilajit can decrease fasting plasma glucose levels. In an animal model, shilajit 100 mg per kg daily enhanced the glucose-lowering ability of both glibenclamide and metformin when given in combination over a 4 week period. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Shilajit full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Shilajit 500 mg, from the product label.

youtheory

See all youtheory products
Name
Nutrawise
City
Irvine
State
CA
ZipCode
92618
Phone Number
1.888.271.8976
Web Address
youtheory.com
Pharmacist Counseling Corner

Shilajit 500 mg by youtheory: Common Questions

Does Shilajit 500 mg by youtheory interact with any medications?
Yes. Based on its ingredients, Shilajit 500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shilajit 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Youtheory Shilajit if I'm pregnant?
No. The safety data advises against shilajit during pregnancy, and there's also contamination risk if the product isn't purified. Talk with your doctor before using it.
Can I take it while breastfeeding?
No. Safety is unknown while breastfeeding, so it's best avoided. Your doctor or pharmacist can discuss safer options with you.
Does shilajit actually work for Alzheimer disease, low testosterone, or bone health?
The evidence isn't established in the data we hold. For Alzheimer disease, sexual dysfunction, athletic performance, benign prostatic hyperplasia, and osteoporosis, there is insufficient reliable evidence to rate its effectiveness.
What are the side effects?
Shilajit is generally well tolerated. Headache has been reported rarely. A small number of cases of allergic reactions and one case of high blood pressure have been reported, though the link to shilajit couldn't always be confirmed.
Does the product contain fillers?
Yes, the capsule contains inactive ingredients including vegetable cellulose, microcrystalline cellulose, and magnesium stearate to help hold it together. The active ingredient is shilajit.
Is it safe to use an unpurified shilajit product?
No. Unpurified shilajit may contain heavy metals or other contaminants. Use only purified, tested brands.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Shilajit 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shilajit 500 mg label
Go deeper

The Full Monographs Behind Shilajit 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Shilajit

Interacts with 86 drugs

Shilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and vitality. Human evidence is limited and m...

Read the full Shilajit monograph →
Sources

Sources & How We Checked

Shilajit 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Shilajit 8 references
  1. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
  2. Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
  3. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
  4. Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
  5. Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
  6. Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
  7. Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
  8. Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.

See these in context on the Shilajit monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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